CSDP Curriculum Vitae Richard Lange 2020

r lange UT Southwestern Medical Center

CSDP-2020-Curriculum-Vitae-Richard-Lange
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Curriculum Vitae (updated January 2020)
RICHARD A. LANGE, M.D., M.B.A.

Position

President, Texas Tech University Health Sciences Center El Paso Dean, Paul L. Foster School of Medicine

Office Address

Texas Tech University Health Sciences Center El Paso 5001 El Paso Dr Suite 3200 El Paso, TX 79905

Office: Mobile FAX: Email:

915-215-4300 210-218-2706 915-783-5533 Richard.Lange@ttuhsc.edu

Personal Data

Birthplace: Citizenship: Marital Status: Spouse:

Anchorage, Alaska U.S. Married Joy Bobette Lange

Certification and Licensure

Medical Licensure:

Texas Maryland

G3543 D0061138

Board Certifications:

Internal Medicine (#105140), 9/85 Cardiovascular Disease (#105140), 11/87 Interventional Cardiology (#105140), 09/03

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Education

1974-1978

B.S.

North Texas State University

Biochemistry, Summa Cum Laude, GPA 4.0

1978-1982

M.D.

Univ of TX Southwestern Med Ctr (UTSWMC) Alpha Omega Alpha, rank 13/208

2004-2008

M.B.A.

Carey Business School, Johns Hopkins University GPA 3.96

Postdoctoral Training

1982-1983

Internship, Internal Medicine, The Johns Hopkins Hospital

1983-1985

Residency, Internal Medicine, The Johns Hopkins Hospital

1985-1988

Fellowship, Cardiovascular Medicine, UTSWMC

Faculty Appointments

1988-1992

Assistant Professor of Internal Medicine, UTSWMC

1992-1999

Associate Professor of Internal Medicine, UTSWMC

1993- 2003

Co-Director, Adult Congenital Heart Disease Clinic, UTSWMC

1999-2003

Professor of Internal Medicine (Tenured), UTSWMC

1999-2003

Director, Cardiology Fellowship Training Program, UTSWMC

2001-2003

Director, Bernard & Audrey Rapoport Center for CV Research, UTSWMC

2004-2008

Professor of Medicine (Tenured) Johns Hopkins University School of Medicine (SOM)

2004-2008 2004-2007
2005-2008 2008-2014 2008-2014 2008-2014 2014-current 2014-current 2014-current

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Chief, Clinical Cardiology Johns Hopkins University SOM
Associate Director, Donald W. Reynolds Cardiovascular Clinical Research Center Training Program Johns Hopkins University SOM
Co-Director, Cardiology Fellowship Program Johns Hopkins University SOM
Professor of Internal Medicine (Tenured) Univ of Texas Health Science Center San Antonio
Executive Vice Chairman, Dept of Medicine Univ of Texas Health Science Center San Antonio
Director, Office of Educational Programs, Department of Medicine Univ of Texas Health Science Center San Antonio
President Texas Tech University Health Science Center El Paso
Dean, Paul L. Foster School of Medicine Texas Tech University Health Science Center El Paso
Professor of Internal Medicine (Tenured) Texas Tech University Health Science Center El Paso

Hospital and Administrative Appointments

1988-1991

Associate Director, Cardiac Pacing Service, Parkland Memorial Hospital, UTSWMC

1988-1991

Associate Director, Cardiac Catheterization Laboratory Parkland Memorial Hospital, UTSWMC

1991-1992

Director, Cardiac Pacemaker Service, Parkland Memorial Hosp, UTSWMC

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1991-1999

Director, Cardiac Catheterization Laboratory, Parkland Memorial Hospital, UTSWMC

2000-2002

Chief of Staff Zale-Lipshy University Hospital

2014-current

Board Member (Ex-Officio) University Medical Center, El Paso

2014-current

Board Member (Ex-Officio) El Paso Children's Hospital

2014-current

Joint Advisory Board The Hospitals of Providence, Transmountain Campus

2016-current

Board Member (Ex-Officio) Tenet Hospitals

Awards/Honors

1979 1981 1983 1985 1986 1994 1996 1998 1998 1999 1999 1999
2000 2000 2000 2000 2001 2002

Chilton Foundation Fellowship Alpha Omega Alpha Outstanding Housestaff Teaching Award, The Johns Hopkins Hospital Daniel Baker Award (Outstanding Senior Resident), The Johns Hopkins Hospital National Institutes of Health Training Fellowship Jonsson-Rogers Chair in Cardiology (held until 2004) Best Doctors in America (1996-2018) Merit Award, American Heart Association, Dallas Division Marquis Who's Who in Medicine and Healthcare (1998-2012) Outstanding Teacher Award, UTSWMC, Sophomore Class of 2001 Outstanding Teacher Award, UTSMWC, Freshman Class of 2002 Outstanding Teacher Award, UTSWMC School of Allied Health, PA class of 1999 Outstanding Teacher Award, UTSWMC, Sophomore Class of 2002 Outstanding Intellectuals of the 21stCentury American Clinical and Climatological Association (2000-2010) Richard A. Lange Chair in Cardiology (Inaugural holder, 2000-2003) Outstanding Teacher Award, UTSWMC, Sophomore Class of 2003 Outstanding Teacher Award, UTSWMC, Sophomore Class of 2004

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2002 2002 2002 2003 2003 2003 2004 2004 2004 2004 2004 2005 2005 2007 2008 2008 2008
2008 2009 2010 2010 2011 2011 2012 2012 2013 2013 2013 2013
2014 2015 2015 2015 2016 2017
2017

Outstanding Teacher Award, 2002, Freshman Class of 2005 Internal Medicine Housestaff Outstanding Teacher Award, UTSWMC Marquis Who's Who in America 2002-2015 Best Doctors in Dallas, D Magazine (peer selected), 2003-08 Outstanding Teaching Award, UTSWMC, Sophomore Class of 2005 Outstanding Teaching Award, UTSWMC, Freshman Class of 2006 Academic Keys Who's Who in Medical Sciences Education Outstanding Teaching Award, UTSWMC, Sophomore Class of 2006 Outstanding Teaching Award, UTSWMC, Freshman Class of 2007 Theodore E. Woodward Award, American Clinical and Climatologic Association E. Cowles Andrus Professorship, Johns Hopkins University (2004-2008) Leadership Development Program, Johns Hopkins University Fortuin Teaching Award, Johns Hopkins University Best Doctors in Baltimore, Baltimore Magazine (peer selected) 1st Annual Johns Hopkins Cardiology Teaching Award NIH Master Teacher International Health and Medical Media Awards (Finalist, in the Audio Programming category for www.hopkinsmedicine.org/mediaII/podcasts.html.) Best Doctors in Baltimore, Baltimore Magazine (peer selected) L. David Hillis Distinguished Professorship AMWA Barbara Sanford Equity Teaching Award, UTHSCSA Best Doctors in San Antonio, San Antonio Magazine (peer selected, 2010-2013) Commencement speaker, UTHSCSA Medical School Graduation Award for Excellence in Medical Education, UTHSCSA, Senior Class of 2011 Outstanding Faculty Award, UTHSCSA Senior Class of 2012 Who's Who in North American Education Best Doctors in San Antonio, San Antonio Magazine, (peer selected, since 2010) Outstanding Faculty Award, UTHSCSA Senior Class of 2012 Arnold B Gold Humanism Award America's Top Cardiologists (Consumer's Research Council of America, 20132017) Outstanding Faculty Award, UTHSCSA Senior Class of 2013 Commencement speaker, TTUHSC El Paso Paul L. Foster School of Medicine Commencement speaker, Univ of Texas School of Public Health, MPH program Southern Society for Clinical Investigation Commencement speaker, TTUHSC El Paso Paul L. Foster School of Medicine America's Top Cardiologists (Consumer's Research Council of America, annually since 2013) Nominee, El Pasoan of the Year

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2019 Best Doctors in America (peer selected, annually since 1996) 2019 Texas Super Doctors, Texas Monthly (peer selected, annually since 2016) 2019 Vision of Excellence Award, El Paso Hispanic Chamber Commerce

Visiting Professorships

1998 1999 2004 2007 2007 2013 2013 2018

University of Virginia (Charlottesville) Cleveland Clinic Medical Institution (Cleveland) Univ of Texas Southwestern Medical Center (Dallas) Baylor School of Medicine (Houston, TX) University of North Carolina (Craige Memorial Lecture) Texas A&M, Scott and White (Temple, TX) Baylor School of Medicine (Houston, TX) Chief Residents' Visiting Professor, Baylor School of Medicine (Houston, TX)

Organizations

American Clinical and Climatological Association (Secretary-Treasurer) American College of Cardiology (Fellow) American College of Physicians (Fellow) American Heart Association
- Council on Clinical Cardiology (Fellow) - Council on Atherosclerosis, Thrombosis and Vascular Biology Association of Academic Health Centers Association of University Cardiologists Association of American Medical Colleges - Council of Deans Association of Subspecialty Professors Council of Public University Presidents and Chancellors - Legislative Session Advisory Committee - Economic Impact Work Group International Society for Adult Congenital Cardiac Disease International Institute of Medicine - Continuing Education Advisory Committee National Marfan Foundation Rotary International Society of Cardiac Angiography and Intervention (Fellow) Southern Society for Clinical Investigation

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Texas Club of Cardiologists

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Federal Committees

2010-2012

Consultant, Food and Drug Administration (FDA), Circulatory System Devices Panel, Medical Devices Advisory Committee, Center for Devices and Radiological Health, Department of Health and Human Services Jan 2011 ­ AED 510K system Jan 2011 - RX Acculink Carotid Stent System Jun 2011 - Panel Sapien-Edwards Percutaneous Aortic Valve Jun 2011 - Berlin Pediatric LVAD Oct 2011 - Zilver-PTX-Drug-Eluting Peripheral Stent Dec 2011 - CRT-D Dec 2011 - CardioMEMS Apr 2012 - Heartware VAS Apr 2012 - Cameron ICD May 2012 - ASD occluder devices (Gore, AGA/St Jude) Jun 2012 - TAVR (Sapien)

2012-2016 2016-2018

Permanent Member, FDA, Circulatory System Devices Panel, Medical Devices Advisory Committee, Center for Devices and Radiological Health, Department of Health and Human Services Sept 2013 ­ ECMO and external pacemaker pulse generators (EPPGs) Oct 2013 ­ CRT-P/CRT-D indications, CardioMEMS Nov 2013 ­ Orbital atherectomy system (OAS) ­ special consultant Dec 2013 ­ Watchman LA appendage closure device May 2014 ­ ECMO and ResQCPR® System active
compression/decompression (ACD) CPR device June 2014 ­ Lutonix drug-coated balloon PTA device Oct 2014 - Watchman LA appendage closure device
Minimally manipulated allograft heart valves Feb 2016 ­ Leadless Pacemakers, Medtronic/St Jude Mar 2016 ­ Bioresorbable Vascular Scaffold (BVS) System Mar 2016 ­ AngelMed ST monitoring system June 2016 ­ (Chaired) Heater Cooler Devices and Nontuberculous
mycobacterial infections SGA (Consultant), FDA, Circulatory System Devices Panel, Medical Devices Advisory Committee, Center for Devices and Radiological Health, Department of Health and Human Services July 2018 ­ Cordis AAA Incraft Stent Graft System

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2018-current

Chair, FDA Circulatory System Devices Panel, Medical Devices Advisory Committee, Center for Devices and Radiological Health, Department of Health and Human Services Dec 2018 ­ OPTIMIZER Cardiac Contractility Modulation
(Impulse Dynamics) Dec 2018 ­ Anti-Hypertensive Devices Jun 2019 ­ Paclitaxel eluting stents/balloons in peripheral vascular disease

University Committees/Assignments

1992-1994 1993-2003 1992-2003 1996-2003 2002 2003 2003-2004 2005-2008 2005-2008 2005-2008 2005-2008 2005-2008 2005-2008 2004-2008 2005-2006
2005-2008 2005-2008 2006-2008
2008-curr 2008-curr 2008-2009 2008-curr 2009-2010 2010-2011 2012-2014 2013-2014

Clinical Practice Steering Committee, UTSWMC Internal Medicine Internship Advisor, UTSWMC Advisory Committee, Invasive CV Tech Program, Dallas Cou Comm Coll Medical Student Selection Committee, UTSWMC Pediatric Chairman Search Committee, UTSWMC IRB Review Committee Ad Hoc Task Force, UTSWMC Clinical Task Force, UTSWMC Curriculum Reform Committee, Johns Hopkins Univ SOM Intern Selection Committee, Johns Hopkins University SOM Cardiology Fellowship Selection, Director, Johns Hopkins Univ SOM Co-Director, MS2 CV Pathophysiology, Johns Hopkins University SOM Women's Multidisciplinary Strategy Team, Johns Hopkins Univ SOM Safety & Operations Committee, Johns Hopkins Univ SOM Clinical Practice Assn Contracting Committee, Johns Hopkins Univ SOM Clinical Practice Association Contracting Committee, Vice Chairman, Johns Hopkins Univ SOM Medicare Strategy Committee, Johns Hopkins Univ SOM Medicine, LOS Committee, Johns Hopkins Univ SOM Clinical Practice Association Contracting Committee, Chairman, Johns Hopkins Univ SOM Joint Affiliation Operating Management Committee, UTHSCSA Research Equipment and Space Allocation Committee, UTHSCSA XYZ Compensation Task Force, UTHSCSA Clinical Competence Committee, UTHSCSA Promotions and Tenure Advisory Committee, UTHSCSA Chair, Hematology/Oncology Chairman Search Committee, UTHSCSA Specialty Access Committee, UTHSCSA Chair, Search Committee, RAHC-DHR Int Medicine Program Director

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2013-2014 2013-2014 2013-2014 2014 2014-curr
2014-curr 2014-curr 2016 2016 2016-curr 2017-curr
2019-curr

Chair, Search Committee RAHC-VBMC Int Medicine Assoc Program Dir Clinical Advisory Board, Doctor of Medical Physics Program NIH institutional reviewer (KL2 awards) AOA, Selection Committee, UTHSCSA Higher Education Fund Formula Study Committee Texas Higher Education Coordinating Board (THECB) Texas Tech University Foundation Texas Tech Physician Associates, Executive Committee Presidential Search Committee (ad hoc member), Texas Tech Univ School of Public Health Dean's Search Committee, Univ of Texas El Paso
Facilities and Planning Committee, TTUHSC El Paso Temporary Faculty, Metallurgical, Materials and Biomedical Engineering Department, Univ of Texas El Paso Presidential Search Committee (ex officio), TTUHSC

Hospital Committees

1989- 2003 1996-1998
1997-2003
1998-2000
2000-2002
2004-2008
2005-2008
2013-2014 2014-curr 2014-curr 2014-2015
2014-curr 2015

Quality Assurance Committee, Zale-Lipshy Univ Hosp, Dallas, TX Secretary-Treasurer, Medical Executive Committee, Zale-Lipshy U Hosp, Dallas, TX Performance Improvement Committee, Zale-Lipshy Univ Hosp, Dallas, TX Vice Chairman, Medical Executive Committee, Zale-Lipshy Univ Hosp, Dallas, TX Chairman, Medical Executive Committee, Zale-Lipshy University Hosp, Dallas, TX Heart Institute Board of Governors, The Johns Hopkins Hospital, Baltimore, MD Women's Multidisciplinary Strategy Team, The Johns Hopkins Hospital, Baltimore, MD Heart Vascular Institute, University Hospital, San Antonio, TX Board Member (Ex-Officio), El Paso Children's Hospital, El Paso, TX Board Member (Ex-Officio), University Medical Center, El Paso, TX Medical Executive Committee (Ex-Officio), Univ Medical Center, El Paso, TX Joint Advisory Board, Providence Hospital Network, El Paso, TX CEO Search Firm Selection Committee, University Medical Center, El Paso, TX

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2016 2016-curr 2016 2016-curr 2017-curr

CEO Search Committee, University Medical Center, El Paso, TX Medical Executive Committee, Univ Medical Center, El Paso, TX CEO Search Committee, El Paso Children's Hospital, El Paso, TX Neonatal ICU Committee, El Paso Children's Hospital, El Paso, TX Cardiovascular Committee, The Hospitals of Providence Transmountain, El Paso, TX

Organizational Leadership

1994-2002
1996-1998
1998-2002
1999-2002
2000-2001
2001-2002
2000-2004
2000-2004
2000-2002 2001-2007 2002-2003 2003-2004 2005-2009 2006-2008
2008-2009 2011-2012 2012-curr 2013-2015 2013-curr 2014-curr 2014-curr

Research Advisory and Allocation Committee, American Heart Associate, Texas Affiliate Vice Chairman, Research Advisory and Allocation Committee, American Heart Association, Texas Affiliate Chairman, Research Advisory and Allocation Committee, American Heart Association, Texas Affiliate National Scientific Classification Task Force American Heart Association Vice Chairman, Research Committee, Western Affiliates American Heart Association Chairman, Research Committee, Western Affiliates American Heart Association Board of Directors, American Heart Association, Texas Affiliate Working Group on Extramural Program Evolution American College of Cardiology Scientific Advisory Board, Intl Academy of Cardiology Scientific Advisory Panel, Doris Duke Charitable Foundation CV Panel Vice President, American Heart Association, Texas Affiliate President, American Heart Association, Texas Affiliate, 2003-2004 Samuel Levine Award Committee, Council on Clinical Cardiology, AHA Sister-To-Sister, Everyone Has a Heart Foundation Executive Leadership Committee ACC Spotlight Session Planning Committee Chair, Scientific Session Program Committee, Am College of Cardiology Secretary/Treasurer, American Clinical and Climatological Association Assoc Editor, Lifelong Learning Program, Am College of Cardiology Sarnoff Foundation, Scientific Committee El Paso County Medical Society, Ex-Officio Member Medical Center of Americas, Board Member

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2014-curr
2014-curr 2015-curr 2015-curr 2015-curr 2016-curr 2018-curr
2019-curr

Higher Education Fund Formula Study Committee Texas Higher Education Coordinating Board (THECB) AziCATS (Univ of Arizona CTSA) Executive Council Greater El Paso Chamber of Commerce, Governing Board Borderplex Economic Alliance, Life Sciences Task Force PHIX (Paso del Norte Health Information Exchange), Board of Directors Executive Leadership Committee, AHA, El Paso Affiliate FEMAP Foundation (Federacion Mexicana de Asociaciones Privadas, Mexican Federation of Health and Community Development) ­ Board of Directors Council of Public University Presidents and Chancellors o 86th Legislative Session Follow-up Work Group o 87th Legislative Session Planning Session Work Group o Economic Impact/Outcomes Study Coordination Work Group

Writing Committees (National Organizations)

2008 2010 2010 2011
2011 2011
2012 2013 2013 2014 2015 2015 2016
2016 2016
2016 2019

ACC/AHA Task force: Training in Clinical Cardiology ACCF/AHA Guidelines for Coronary Artery Bypass Graft Surgery ACCF/AHA Guidelines for Percutaneous Coronary Revascularization ACCF/AHA Appropriate Use Criteria For Diagnostic Catheterization (External Reviewer) ACCF/AHA, Sexual Activity and Heart Disease ACCF/AHA Science Advisory on Latency of Visual ECG Displays of Hospital Telemetry Systems (External Reviewer) ACCF/AHA Pet Ownership and Cardiovascular Disease ACCF/AHA Stable Ischemic Heart Disease Update ACCF/AHA Perioperative Guidelines (External Reviewer) ACCF/AHA Valvular Heart Disease Guidelines (External Reviewer) ACCF/AHA Focused Update on Primary PCI for Patients with STEMI ACCF/AHA Dual Antiplatelet Therapy in Patients with CAD ACCF Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation (External Reviewer) ACCF/AHA, Vice Chair, Meditation and Cardiovascular Risk Reduction AHA/ACC Focused Update on the Management of Patients With Valvular Heart Disease (External Reviewer) AHA Meditation and Cardiovascular Disease SCAI, Finances and Economics of Cardiac Catheterization Laboratories (External Reviewer)

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Grant Reviews

1994-2004 2001-2007 2012- curr 2012- curr 2013- curr 2013- curr 2013- curr

American Heart Association Doris Duke Charitable Foundation Ministry of Education and Science, Russian Federation Qatar National Research Foundation Sarnoff Foundation Health Research Board (Ireland) NIH (KL2 awards)

Doctoral Thesis Committees

2008 2019 2019

Nima Kasraie, Biomedical Engineering (Univ of Texas HSC San Antonio) Beu Oropeza, Biomedical Engineering (Univ of Texas El Paso) Michael Jiang, Biomedical (Cleveland Clinic University)

Course Director

1996-2002 2004-2008 2006-2008 2008-2014

Co-Director, Problems in Clinical Cardiology American College of Cardiology Course, Sante Fe, NM Topics in Cardiovascular Medicine, Johns Hopkins University, Baltimore, MD Cardiovascular Pathophysiology (MS2) Johns Hopkins SOM Co-Director, Cardiovascular Medicine (MS2) UTHSCSA

Editorial Boards

Emedicine/Medscape ­ Chief Editor (2011-current)
Catheterization and Cardiovascular Intervention - Associate Editor (2011-current)
Journal of Investigative Medicine - Associate Editor (2017-current) - Editorial Board (2015-17)
Circulation - Editorial Board (2016-current)
JACC Cardiovascular Intervention - Editorial Consultant (2017-current)

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American Journal of Cardiology - Editorial Board (2010-current)
Journal of Cardiovascular Pharmacology & Therapeutics - Editorial Board (2010-current)
American College of Cardiology, Lifelong Learning Program - E-Learning Activities Editor (2015-current)
Cardiology Review - Editorial Advisory Board (2014-current)
Cardiovascular System (current) - Editorial Board (2016-current)
American College of Cardiology, Lifelong Learning Program - Associate Editor (2013-2015)
CardioExchange (NEJM) - Interventional Moderator (2011-2015)
CardioExchange (NEJM) - Interventional Moderator (2011-2015)
Theheart.org (past) - Editorial Board
Practical Reviews, Cardiology (past) - Administrative Editor
Cardiology, Oakstone Medical Publishing (past) - Editor
Manuscript Review American Heart Journal American Journal of Cardiology American Journal of Physiology Annals of Internal Medicine Biological Psychiatry BioMed Central Research Notes BMJ Open Catheterization and Cardiovascular Intervention Chest Cleveland Clinic Journal Clinical Infectious Disease Consultant Circulation Circulation: Cardiovascular Interventions Expert Review of Cardiovascular Therapy Future Cardiology

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Journal of the American College of Cardiology JACC Cardiovascular Intervention JAMA Cardiology Journal of Cardiac Failure Journal of Cardiovascular Pharmacology and Therapeutics Journal of Heart Valve Disease Journal of Invasive Cardiology Journal of Investigative Medicine Kidney International International Journal of Cardiology Italian Heart Journal Lancet The Medical Letter Molecular Biology and Medicine National Geographic New England Journal of Medicine Pediatrics Preventive Medicine Science and Perspectives (NIDA)
Funded Projects (Multicenter or Industry-Sponsored Trials)
Co-investigator, TIMI, phase II (completed)
Clinical Evaluation of the Velcom-100, Waters Instr, Inc., $16,000 (completed)
Recombinant Platelet Factor 4 After Cardiac Catheterization Repligen Corporation, $209,280 (completed)
Co-investigator, SHOCK Trial (PTCA in patients with myocardial infarction and cardiogenic shock), NIH funded $2800 per patient (completed).
Co-Investigator TIMI 18, TACTICS Trial (completed).
Primary Investigator, A to Z Trial (completed).
Primary Investigator and U.S. Steering Committee, TARGET Trial (completed).
Co-Investigator, OAT Trial (Open Artery Trial) (completed)

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Co-Investigator, SYNERGY Trial (completed) Primary Investigator, RESPECT Trial (completed) Merlin-TIMI 36, CVT 3036, Sub-investigator (completed) CORE-64, MDCT vs Cath (Toshiba) (completed) Funded Projects (Agencies)

American Heart Assn, Texas Affiliate, BGIA

11/89-10/91

Role (Primary Investigator)

Direct: $55,000

"Local Fibrinolytic Potential in Patients with Unstable Angina

GOAL: The aim of this project was to investigate the role of tissue plasminogen

activator and its inhibitor in the development of unstable angina.

NIH (PI: Victor, Ron)

9/96-8/99

(Role: Co-Investigator, 10%)

$774,000

"Cocaine and Sympathetic Nerve Activity in Humans"

GOAL: The aim of this project was to establish the role of central and peripheral

sympathetic nerve activation in the cardiovascular effects of cocaine in healthy

human volunteers

Donald W. Reynolds Foundation (Weiss)

07/03-6/10

Reynolds Cardiovascular Clinical Research Program

$3,512,693

Sudden Cardiac Death

GOALS: The Johns Hopkins Reynolds Center is a broad, multidisciplinary

approach to the problem of sudden cardiac death (SCD) associated with

atherosclerosis. The primary goal is to develop new means to identify individuals at

risk for SCD and to develop novel therapies to prevent SCD in those individuals.

HL081028-01 (PI: Hare, Marban, Lange)

09/30/05 - 08/31/10

NIH

$9.2 million

(Role: Primary Investigator)

Cellular Cardiomyoplasty for Acute and Chronic Ischemia"

GOALS: This Specialized Center for Cell Therapeutics proposal aims to develop

cellular cardiomyoplasty for the treatment of ischemic heart disease, both post-

myocardial infarction, left ventricular dysfunction as well as chronic ischemic

cardiomyopathy.

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5 R01DA12777-07(PI: Lai, Shenghan)

9/1/05 ­ 11/30/10

NIH/NIDA (Role: Co-investigator, 5%)

$431,180

"Subclinical Atherosclerosis in HIV + Black Cocaine Users"

GOALS: The aim of this project is to describe prospectively the etiology and natural

history of atherosclerosis and the ability of non-invasive tools to measure

atherosclerotic burden in black men and women with HIV infection who abuse

cocaine, and to investigate whether HIV infection, cocaine abuse, and protease

inhibitor treatment accelerate atherosclerosis.

Cardiovascular Care Initiative

1/07-12/12

Govt of Trinidad and Tobago

$30 million/5 yrs

(Role: Originator )

GOALS: To assess and improve CV care in Trinidad and Tobago, and provide

training to local physicians, nurses, and technicians in the areas of preventive,

electrophysiology, invasive, and noninvasive cardiology.

Rbt J Kleberg and Helen C Kleberg Foundation

5/10-4/16

" A Model for Excellence in Medical Research

$2.475 million/6yrs

For the Future of Health in South Texas"

GOALS: To provided MPH degree to 42 medical students and MPH certificate

training to 25 residents and to implement formalized training, mentorship, and

research models that will impact patient care in South Texas.

N01-HV-0024 (PI Lindsey)

08//10-08//15

NIH

$11.6 million

(Role: Co-Investigator)

UTHSCSA Cardiovascular Proteomics Center

GOALS: To develop novel proteomic technologies to identify predictive markers of

adverse remodeling of the left ventricle following myocardial infarction, focusing

on extracellular matrix generation as a key initiating event.

Publications

Articles

1. Lange RA, Jacobson MK. Synthesis of pyridine nucleotides by mitochondrial fractions of yeast. Biochem Biophys Res Commun 1977; 76:424-428.

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2. Jacobson EL, Lange RA, Jacobson MK. Pyridine nucleotide synthesis in 3T3 cells. J Cell Physiol 1979; 99:417-426.
3. Albright SC, Wiseman JM, Lange RA, Garrard WT. Subunit structures of different electrophoretic forms of nucleosomes. J Biol Chem 1980; 255:36733684.
4. Van den Berg E, Pacifico A, Lange RA, Wheelan KR, Winniford MD, Hillis LD. Measurement of cardiac output without right heart catheterization: reliability, advantages, and limitations of a left-sided indicator dilution technique. Cathet Cardiovasc Diagn 1986; 12:205-208.
5. McBride W, Lange RA, Hillis LD. Restenosis after successful coronary angioplasty: pathophysiology and prevention. N Engl J Med 1988; 318:17341737.
6. Lange RA, Katz J, McBride W, Moore DM, Hillis LD. Effects of supine and lateral positions on cardiac output and intracardiac pressures. Am J Cardiol 1988; 62:330-333.
7. Lange RA, Hillis LD. How calcium antagonists affect various types of angina. Cardiovasc Rev & Rep 1988; 9:30-33.
8. Lange RA, Hillis LD. Evolving concepts in the treatment of acute myocardial infarction. Am J Med Sci 1988; 31:143-152.
9. Malloy CR, Lange RA, Klein DL, Jeffrey FM, Peshock RM, Willerson JT, Nunnally RL. Spatial localization of NMR signal with a passive surface gradient. J Magn Res 1988; 80:364-369.
10. Lange RA, Moore DM, Cigarroa RG, Hillis LD. Use of pulmonary capillary wedge pressure to assess severity of mitral stenosis: Is true left atrial pressure needed in this condition? J Am Coll Cardiol 1989; 13:825-829.
11. McBride W, Hillis LD, Lange RA. Complete heart block during retrograde leftsided cardiac catheterization. Am J Cardiol 1989; 63:375-376.

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12. Cigarroa RG, Lange RA, Williams RH, Bedotto JB, Hillis LD. Underestimation of cardiac output by thermodilution in patients with tricuspid regurgitation. Am J Med 1989; 86:417-420.
13. Cigarroa RG, Lange RA, Williams RH, Hillis LD. Dosing of contrast material to prevent contrast nephropathy in patients with renal disease. Am J Med 1989; 86:649-652.
14. Lange RA, Hillis LD. Short and long-term complications of coronary angioplasty. Chest 1989; 96:151-157.
15. Cigarroa RG, Lange RA, Hillis LD. Prognosis after acute myocardial infarction in patients with and without residual anterograde coronary blood flow. Am J Cardiol 1989; 64:155-160.
16. Cigarroa RG, Lange RA, Hillis LD. Oximetric quantitation of intracardiac left-toright shunting: Limitations of the Qp/Qs ratio. Am J Cardiol 1989; 64:246-247.
17. Schaefer S, Lange RA, Kulkarni PV, Katz J, Parkey RW, Willerson JT, Peshock RM. In-vivo nuclear magnetic resonance imaging of myocardial perfusion using the paramagnetic agent manganese gluconate. J Am Coll Cardiol 1989; 14:472480.
18. Cigarroa RG, Lange RA, Hillis LD. Quantitative assessment of coronary arterial diameter before and after coronary artery bypass grafting. Am J Cardiol 1989; 64:261-263.
19. Lange RA, Cigarroa RG, Hillis LD. Angiographic characteristics of the infarctrelated coronary artery in patients with angina pectoris after myocardial infarction. Am J Cardiol 1989; 64:257-260.
20. Lange RA, Dehmer GJ, Wells PJ, Tate DA, Jain A, Flores ED, Nichols TC, Hillis LD. Measurement of oxygen consumption and cardiac output: limitations of the metabolic rate meter. Am J Cardiol 1989; 64:783-786.
21. Flores ED, Lange RA. Anomalous origin of the right coronary artery from the left sinus of valsalva. Cardiol Guide 1989; Oct:22-24.

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22. McBride W, Lange RA. Intimal hyperplasia and restenosis after coronary angioplasty. J Vasc Surgery 1989; 10: 579-581.
23. Flores ED, Lange RA, Hillis LD. Endomyocardial biopsy in patients with idiopathic dilated cardiomyopathy. Cardiovasc Rev & Rep 1989; 10:33-39.
24. Lange RA, Cigarroa RG, Yancy CW, Willard JE, Popma JJ, Sills MN, Hillis LD. Cocaine-induced coronary artery vasoconstriction. N Engl J Med 1989; 321:15571562.
25. Flores ED, Lange RA. Acute coronary occlusion following PTCA. Cardiology Guide, 1989; Dec:23-4.
26. Lange RA, Cigarroa RG, Hillis LD. Influence of residual antegrade coronary blood flow on prognosis after myocardial infarction in patients with multivessel coronary artery disease. Coronary Artery Disease 1990; 1:59-63.
27. Cigarroa RG, Lange RA, Popma JJ, Yurow G, Sills MN, Firth BG, Hillis LD. Ethanol induced coronary vasodilation in patients with and without coronary artery disease. Am Heart J 1990; 119:254-259.
28. Hillis LD, Lange RA, Cigarroa RG. Cardiac catheterization. Cardiovasc Rev & Rep 1990; 11:56-74.
29. Lange RA, Cigarroa RG, Wells PJ, Kremers MS, Hillis LD. Influence of antegrade flow in the infarct artery on the incidence of late potentials in acute myocardial infarction. Am J Cardiol 1990; 65:554-558.
30. Flores ED, Lange RA, Bedotto JB, Danziger RS, Hillis LD. Assessment of the sensitivity of hydrogen inhalation in the detection of left-to-right shunting. Cathet Cardiovasc Diagn 1990; 20:94-98.
31. Lange RA, Cigarroa RG, Flores ED, McBride W, Kim AS, Wells PJ, Bedotto JB, Danziger RS, Hillis LD. Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade. Ann Int Med 1990; 112:897-903.
32. Flores ED, Lange RA, Cigarroa RG, Hillis LD. Therapy of acute myocardial infarction in the 1990s. Am J Med Sci 1990; 299:415-24.

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33. Flores ED, Lange RA, Cigarroa RG, Hillis LD. Effect of cocaine on coronary arterial dimensions in atherosclerotic coronary artery disease: enhanced vasoconstriction at sites of significant stenoses. J Am Coll Cardiol 1990; 16:7479.
34. Lange RA, Flores ED, Hillis LD. Cocaine-induced myocardial ischemia and infarction . Cardio 1990; 7:74-79.
35. Lange RA. The cardiovascular complications of cocaine use. Medical Grand Rounds: The University of Texas Southwestern Medical Center. June 28, 1990.
36. Flores ED, Lange RA, Hillis LD. Vasoconstrictive effect of cocaine on coronary arteries. Cardiol Board Rev 1990; 7:47-53.
37. Flores ED, Lange RA, Hillis LD. Relation of mean pulmonary arterial wedge pressure and left-ventricular end-diastolic pressure. Am J Cardiol 1990; 66:15321533.
38. Kremers MS, Black WH, Lange RA, Wells PJ, Solo M. Electrocardiographic signal-averaging during atrial pacing: effect of cycle length on the terminal QRS in patients with and without inducible ventricular tachycardia. Am J Cardiol 1990; 66:1095-1098.
39. Brogan WC, Lange RA, Hillis LD. Simplified formula for the calculation of mitral valve area: Potential inaccuracies in patients with tachycardia. Cathet Cardiovasc Diagn 1991; 23:81-83.
40. Hillis LD, Lange RA. Serotonin and acute ischemic heart disease. N Engl J Med 1991; 324:688-690.
41. Brickner ME, Grayburn PA, Carry MM, Fadel B, Carry MM, Eichhorn EJ, Lange RA, Taylor AL. Detection of patent foramen ovale by Doppler color flow mapping in patients undergoing cardiac catheterization. Am J Cardiol 1991; 68:125-129.
42. Schaefer S, Lange RA, Gutekunst DP, Parkey RW, Willerson JT, Peshock RM. Contrast-enhanced magnetic resonance imaging of hypoperfused myocardium. Invest Radiol 1991; 26:551-556.

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43. Brogan WC, Lange RA, Kim AS, Moliterno DJ, Hillis LD. Alleviation of cocaine-induced coronary vasoconstriction by nitroglycerin. J Am Coll Cardiol 1991; 18; 581-586.
44. Glamann DB, Lange RA, Hillis LD. Beneficial effect of long-term beta-blockade after myocardial infarction in patients without antegrade flow in the infarct artery. Am J Cardiol 1991; 68:150-154.
45. Lange RA, Flores ED, Hillis LD. Restenosis after coronary balloon angioplasty. Annual Review of Medicine 1991; 42:127-132.
46. Brogan WC III, Hillis LD, Lange RA. Stenotic valvular area: Gorlin equation versus the "simplified formula." Cardio 1991; 8:40-44.
47. Glamann DB, Lange RA, Hillis LD. Incidence and significance of a "step-down" in oxygen saturation from superior vena cava to pulmonary artery. Am J Cardiol 1991; 68:695-697.
48. Brogan WC III, Lange RA, Hillis LD. Contrast agents for catheterization: conceptions and misconceptions. Am Heart J 1991; 122:1129-1135.
49. Brogan WC III, Kemp PM, Bost RO, Glamann DB, Lange RA, Hillis LD. Collection and handling of clinical blood samples to assure the accurate measurement of cocaine concentration. J Anal Toxicol 1992; 16:152-154.
50. Brogan WC, Lange RA, Hillis LD. Accuracy of various methods of measuring the transvalvular pressure gradient in aortic stenosis. Am Heart J 1992; 123:948953.
51. Boehrer JD, Lange RA, Willard JE, Hillis LD. Influence of collateral filling of the occluded infarct-related coronary artery on prognosis after acute myocardial infarction. Am J Cardiol 1992; 69:10-12.
52. Glamann DB, Lange RA, Corbett JR, Hillis LD. Utility of various radionuclide techniques for distinguishing ischemic from nonischemic dilated cardiomyopathy. Arch Int Med 1992; 152:769-772
53. Brogan WC III, Hillis LD, Flores ED, Lange RA. The natural history of isolated left ventricular diastolic dysfunction. Am J Med 1992; 92:627-630.

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54. Brogan WC III, Glamann DB, Lange RA, Hillis LD. Comparison of single plane and biplane ventriculography for determination of left ventricular volume and ejection fraction. Am J Cardiol 1992; 69:1079-1082.
55. Brogan WC III, Lange RA, Glamann DB, Hillis LD. Recurrent coronary vasoconstriction caused by intranasal cocaine. Ann Int Med 1992; 116:556-561.
56. Boehrer JD, Moliterno DJ, Willard JE, Snyder RW II, Horton RP, Glamann DB, Lange RA, Hillis LD. Hemodynamic effects of intranasal cocaine in man. J Am Coll Cardiol 1992; 20:90-93.
57. Boehrer JD, Lange RA, Willard JE, Grayburn PA, Hillis LD. Advantages and limitations of methods to detect, localize, and quantitate intracardiac left-to-right shunting. Am Heart J 1992; 124:448-455.
58. Moliterno DJ, Lange RA, Willard JE, Boehrer JD, Hillis LD. Does restoration of antegrade flow in the infarct-related coronary artery days to weeks after acute myocardial infarction improve long-term survival? Coronary Artery Disease 1992; 4:299-304.
59. Willard JE, Lange RA, Hillis LD. The use of aspirin in ischemic heart disease. N Engl J Med 1992; 327:175-181.
60. Lange RA, Hillis LD. Nonionic contrast media: Is it for everyone undergoing cardiovascular angiography? Coronary Artery Disease 1992; 4:345-346.
61. Hillis LD, Lange RA. Time for a prospective randomized trial of the "open artery hypothesis" in survivors of myocardial infarction. Am J Cardiol 1992; 69:13591360.
62. Boehrer JD, Lange RA, Willard JE, Hillis LD. Lack of relation of coronary sinus oxygen content to extent of coronary artery disease or left ventricular dysfunction. Am J Cardiol 1992; 70:1623-1625.
63. Boehrer JD, Lange RA, Willard JE, Hillis LD. Markedly increased periprocedure mortality of cardiac catheterization in patients with severe narrowing of the left main coronary artery. Am J Cardiol 1992; 70:1388-1390.

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64. Boehrer JD, Glamann DB, Lange RA, Willard JE, Brogan WC III, Eichhorn EJ, Grayburn PA, Anwar A, Hillis LD. Effect of coronary angioplasty on late potentials one to two weeks after myocardial infarction. Am J Cardiol 1992; 70:1515-1519.
65. Boehrer JD, Lange RA, Willard JE, Grayburn PA, Hillis LD. Advantages and limitations of methods to detect, localize, and quantitate intracardiac right-to-left and bidirectional shunting. Am Heart J 1993; 125:215-220.
66. Boehrer JD, Moliterno DJ, Willard JE, Hillis LD, Lange RA. Influence of labetalol on cocaine-induced coronary vasoconstriction in man. Am J Med 1993; 94: 608-610.
67. Moliterno DJ, Lange RA, Meidell RS, Willard JE, Leffert CC, Gerard RD, Boerwinkle E, Hobbs HH, Hillis LD. Relation of plasma lipoprotein(a) to infarct artery patency in survivors of myocardial infarction. Circulation 1993; 88:935940.
68. Brogan WC III, Grayburn PA, Lange RA, Hillis LD. Prognosis after valve replacement in subjects with severe aortic stenosis and a low transvalvular gradient. J Am Coll Cardiol 1993; 21:1657-1660.
69. Lange RA, Willard JE, Hillis LD. Restenosis: The Achilles heel of coronary angioplasty. Am J Med Sci 1993; 306:265-275.
70. Lange RA, Hillis LD. Management of dilated cardiomyopathy. Hosp Practice 1993; 28: 45-53.
71. Glamann DB, Lange RA, Willard JE, Landau C, Hillis LD. Hydrogen inhalation for detecting intracardiac left-to-right shunting in adults. Am J Cardiol 1993; 72:711-714.
72. Lange RA, Willard JE. The cardiovascular effects of cocaine. Heart and Stroke 1993; 2:136-141.
73. Jacobsen TN, Morgan BJ, Scherrer U, Vissing SF, Lange RA, Johnson N, Ring WS, Rahko PS, Hanson P, Victor RG. Relative contributions of cardiopulmonary and sinoaortic baroreflexes in causing sympathetic activation in the human muscle circulation during orthostatic stress. Circ Res 1993; 73:367-378.

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74. Lange RA, Hillis LD. Immediate angioplasty for myocardial infarction. N Engl J Med 1993; 328:726-728.
75. Lange, RA, Hillis LD. Cocaine and the heart. Resident and Staff Physician 1993; 39(12): 49-52
76. Willard JE, Hillis LD, Lange RA. The importance of a patent infarct-related artery for survival following myocardial infarction. Cardio 1993; 10:33-36.
77. Moliterno DJ, Lange RA, Willard JE, Boehrer JD, Hillis LD. Surgical restoration of antegrade flow in the occluded infarct artery after myocardial infarction improves long-term survival in patients with mulitvessel coronary artery disease. Coronary Artery Disease 1993; 4: 995-999.
78. Negus BH, Snyder RW, Willard JE, Glamann DB, Landau C, Hillis LD, Lange RA. Alleviation of cocaine-induced vasoconstriction by verapamil. Am J Cardiol 1994; 73:510-512.
79. Snyder RW II, Glamann DB, Lange RA, Willard JE, Landau C, Negus BH, Hillis LD. Predictive value of prominent pulmonary arterial wedge v waves in assessing the presence and severity of mitral regurgitation. Am J Cardiol 1994; 73:568-570.
80. Snyder RW II, Lange RA, Willard JE, Glamann DB, Landau C, Negus BH, Hillis LD. Frequency, cause, and effect on operative outcome of depressed left ventricular ejection fraction in mitral stenosis. Am J Cardiol 1994; 73:65-69
81. Landau C, Lange RA, Glamann DB, Willard JE, Hillis LD. Vasovagal reactions in the cardiac catheterization laboratory. Am J Cardiol 1994; 73:95-97.
82. Moliterno DJ, Willard JE, Lange RA, Negus BH, Boehrer JD, Glamann DB, Landau C, Rossen JD, Winniford MD, Hillis LD. Coronary artery vasoconstriction induced by cocaine, cigarette smoking, or both. N Eng J Med 1994; 330:454-459.

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83. Lange RA. The role of percutaneous transluminal coronary angioplasty in the patient with acute myocardial infarction. Medical Grand Rounds: The University of Texas Southwestern Medical Center. Feb 24, 1994.
84. Jacobsen TN, Lange RA, Olivari M-T, Yancy CW, Horn VPH, Ring WS, Baldwin BJ, Cooley RA,Victor RG. Differential reflex control of forearm and calf resistance vessels by chemosensitive cardiac afferent activation. J Appl Physiol 1994; 76:1123-1129.
85. Landau C, Glamann DB, Willard JE, Hillis LD, Lange RA. Coronary angioplasty in patients with acute myocardial infarction. Am J Med 1994; 96:536-543.
86. Landau C, Lange RA, Hillis LD. Percutaneous transluminal coronary angioplasty. N Engl J Med 1994; 330:981-993.
87. Negus BH, Willard JE, Glamann DB, Landau C, Snyder RW II, Hillis LD, Lange RA. Gender-related differences in coronary anatomy of young survivors of myocardial infarction. Am J Cardiol 1994; 74:814-815.
88. Pirwitz MJ, Lange RA, Willard JE, Landau C, Glamann DB, Hillis LD. Use of the left ventricular peak systolic pressure/end-systolic volume ratio in patients with aortic regurgitation and enlarged end-systolic volumes. J Am Coll Cardiol 1994; 24:1672-1677.
89. Negus BH, Willard JE, Glamann DB, Landau C, Snyder RW II, Hillis LD, Lange RA. Coronary anatomy and prognosis of young, asymptomatic survivors of myocardial infarction. Am J Med 1994; 96:354-358.
90. Moliterno DJ, Lange RA, Gerard RD, Willard JE, Lackner C, Hillis LD. Influence of intranasal cocaine on plasma constituents associated with endogenous thrombosis and thrombolysis. Am J Med 1994; 96:492-496.
91. Pirwitz MJ, Lange RA, Willard JE, Landa C, Glamann DB, Foerster EH, Todd E, Hillis LD. Effects of intravenous ethanol on diameter of epicardial coronary arteries. Am J Cardiol 1995; 75:77-79.
92. Daniel WC, Lange RA, Willard JE, Landau C, Hillis LD. Oximetric versus indicator dilution techniques for quantitating intracardiac left-to-right shunting in adults. Am J Cardiol 1995; 75:199-200.

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93. Hundley WG, Clarke GD, Landau C, Lange RA. Willard JE, Hillis LD, Peshock RM. Noninvasive determination of infarct artery patency by cine magnetic resonance angiography. Circulation 1995; 91:1347-1353.
94. Moliterno DJ, Leffert CC, Lange RA, Willard JE, Boerwinkle EA, Hillis LD, Hobbs H. No association between plasma lipoprotein(a) concentrations and the presence of absence of coronary atherosclerosis in African-Americans. Arterioscl Thromb Vasc Biol 1995; 15:850-855.
95. Pirwitz MJ, Willard JE, Landau C, Lange RA, Glamann DB, Kessler DJ, Foerster EH, Todd E, Hillis LD. Influence of cocaine, ethanol, or their combination on epicardial coronary arterial dimensions in man. Arch Int Med 1995; 155:11861191.
96. Hundley WG, Hong FL, Hillis LD, Meshack BM, Lange RA, Willard JE, Landau C, Peshock RM. Quantitation of cardiac output with velocity-encoded, phase difference magnetic resonance imaging. Am J Cardiol 1995; 75:1250-1255.
97. Hundley WG, Hong FL, Lange RA, Pfeifer DP, Meshack BM, Willard JE, Landau C, Willett D, Hillis LD, Peshock RM. Assessment of left-to-right intracardiac shunting by velocity encoded, phase-difference magnetic resonance imaging: A comparison with oximetric and indicator dilution techniques. Circulation 1995; 91:2955-2960.
98. Hundley WG, Li HF, Willard JE, Landau C, Lange RA, Meshack BM, Hillis LD, Peshock RM. Magnetic resonance imaging assessment of the severity of mitral regurgitation: A comparison with invasive techniques. Circulation 1995; 92:1151-1158.
99. Daniel WC, Pirwitz MJ, Horton RP, Landau C, Glamann DB, Snyder RW II, Wells PJ, Willard JE, Hillis LD, Lange RA, Page RL. Electrophysiologic effects of intranasal cocaine in man. Am J Cardiol 1995; 76:398-400.
100. Keeley EC, Lange RA, Landau C, Willard JE, Hillis LD. Quantitative assessment of coronary arterial diameter before and after balloon angioplasty of severe stenoses. Am J Cardiol 1995; 75:939-940.

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101. Keeley EC, Lange RA. Acute myocardial infarction - role of medical therapy versus primary PTCA. Coron Artery Dis 1995; 6:759-764.
102. Daniel WC, Meidell RS, Hillis LD, Lange RA. Transmyocardial fibrinolytic activity in patients with unstable angina pectoris. Coronary Artery Disease 1996; 7:45-49.
103. Pirwitz MJ, Lange RA, Landau C, MeShack BM, Hillis LD, Willard JE. Utility of the 12-lead electrocardiogram in identifying underlying coronary artery disease in patients with depressed left ventricular systolic function. American Journal of Cardiology 1996; 77:1289-1292.
104. Vongpatanasin W, Hillis LD, Lange RA. Prosthetic heart valves. New England Journal of Medicine 1996; 335:407-416.
105. Daniel WC, Pirwitz MJ, Willard JE, Lange RA, Hillis LD, Landau C. Incidence and treatment of elastic recoil occurring in the 15 minutes following successful percutaneous transluminal coronary angioplasty. Am J Cardiol 1996 78:253-259.
106. Daniel WC, Lange RA, Landau C, Willard JE, Hillis LD. Effects of the intracoronary infusion of cocaine on coronary arterial dimensions and blood flow in humans. Am J Cardiol 1996; 78:288-291.
107. Lange RA, Hillis LD. Should thrombolysis or primary angioplasty be the treatment of choice for acute myocardial infarction? Thrombolysis -- The preferred treatment. N Engl J Med 1996 335:1311-1317.
108. Keeley EC, Pirwitz MJ, Landau C, Lange RA, Hillis LD. Foerster EH, Conrad K, Willard JE. Intranasal nicotine spray does not augment the adverse effects of cigarette smoking on myocardial oxygen demand or coronary arterial dimensions. Am J Med 1996; 101:357-363.
109. Hundley WG, Meshack BM, Willett DL, Sayad DE, Lange RA, Willard JE, Landau C, Hillis LD, Peshock RM. Comparison of quantitation of left ventricular volume, ejection fraction, and cardiac output in patients with atrial fibriliation by cine magnetic resonance imaging versus invasive measurements. Am J Cardiol 1996; 78:1119-1123.

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110. Keeley EC, Page RL, Lange RA, Willard JE, Landau C, Hillis LD. Influence of metoprolol on heart rate variability in survivors of remote myocardial infarction. Am J Cardiol 1996; 77:557-560.
111. Hundley WG, Lange RA, Clarke GD, Meshack BM, Payne J, Landau C, McColl R, Sayad DE, Willett DL, Willard JE, Hillis LD, Peshock RM. Assessment of coronary arterial flow and flow reserve in humans with magnetic resonance imaging. Circulation 1996; 93:1502-1508.
112. Dehmer GJ, Lange RA, Tate DA, Pirwitz M, Daniel W, Fisher M, Bonnem EM. A randomized trial of recombinant platelet factor 4 versus protamine for the reversal of heparin anticoagulation in man. Circulation 1996; 94 [Suppl II]:II347-II-352.
113. Keeley EC, Lange RA, Hillis LD, Joglar JA, Page RL. Correlation between timedomain measures of heart rate variability and scatterplots in patients with healed myocardial infarcts and the influence of metoprolol. Am J Cardiol 1997; 79:412414.
114. Vongpatanasin W, Lange RA, Hillis LD. Comparison of cocaine-induced vasoconstriction of left and right coronary arterial systems. Am J Cardiol 1997; 79:492-493.
115. Jacobsen TN, Grayburn PA, Snyder RW II, Hansen J, Chavoshan B, Landau C, Lange RA, Hillis LD, Victor RG. Effects of intranasal cocaine on sympathetic nerve discharge in humans. J Clin Invest 1997; 99:628-634.
116. Pirwitz MJ, Willard JE, Landau C, Hillis LD, Lange RA. A critical reappraisal of the oximetric assessment of intracardiac left-to-right shunting in adults. Am Heart J 1997; 133:413-417.
117. Vongpatanasin W, Willard JE, Hillis LD, Lange RA, Landau C. Acquired myocardial bridging. Am Heart J 1997; 133:463-465.
118. Lange RA, Cigarroa JE, Hillis LD. Thrombolysis or primary PTCA for acute myocardial infarction. ACC Educational Highlights 1997; 12:1-4.
119. Pitts WR, Cigarroa JE, Lange RA, Hillis LD. The "open artery hypothesis" in survivors of myocardial infarction. Clin Cardiol 1997; 20:522-524.

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120. Pitts WR, Lange RA, Cigarroa JE, Hillis LD. Preoperative left ventricular peak systolic pressure/end-systolic volume ratio and functional status following valve surgery in patients with mitral regurgitation and enlarged end-systolic volumes. Am J Cardiol 1997; 79:1493-1497.
121. Pitts WR, Lange RA, Cigarroa JE, Hillis LD. Cocaine-induced myocardial ischemia and infarction: Pathophysiology, recognition, and management. Progr Cardiovasc Dis 1997; 40:65-76.
122. Pitts WR, Lange RA, Cigarroa JE, Hillis LD. Repeat coronary angiography in patients with chest pain and previously normal coronary angiogram. Am J Cardiol 1997; 1086-1087.
123. Hillis LD, Lange RA. Controversies in clinical cardiology. Primary PTCA or thrombolytic therapy: A debate on the preferred therapy of acute MI. Univ. of TX Southwestern Med. Ctr. Grand Rounds; April 1997.
124. Pitts WR, Vongpatanasin W, Cigarroa JE, Hillis LD, Lange RA. Effects of the intracoronary infusion of cocaine on left ventricular systolic and diastolic function in humans. Circulation 1998; 97:1270-1273.
125. Vongpatanasin WP, Brickner ME, Hillis LD, Lange RA. The Eisenmenger syndrome in adults. Ann Int Med 1998; 128;745-755.
126. Kessler DJ, Pirwitz MJ, Horton RP, Canby RC, Welch PJ, Joglar JA, Hamdan MH, Lange RA, Page RL. Intracardiac shunts resulting from transseptal catheterization for ablation of accessory pathways in otherwise normal hearts. Am J Cardiol, 1998; 82;391-392.
127. Devaraj S, Vega G, Lange R, Grundy S, Jialal I. Remnant-like lipoprotein cholesterol levels in patients with dysbetalipoproteinemia and coronary artery disease patients. Am J Med 1998; 104:445-450.
128. Pitts WP, Lange RA, Cigarroa JG, Hillis LD. Coronary arterial anatomy in patients with left ventricular systolic dysfunction without previous chest pain or myocardial infarction. Am J Cardiol 1998; 82:1530-1531.

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129. Lange RA, Hillis LD. Use and overuse of angiography and revascularization for acute coronary syndromes. N Engl J Med 1998; 38;1838-1839.
130. Hillis LD, Cigarroa JE, Lange RA. Infarct artery patency and survival following myocardial infarction. Trans Am Clin Climat Assn. 1999:110:93-104.
131. Pitts WR, Lange RA, Cigarroa JE, Hillis LD. Predictive value of prominent right atrial v waves in assessing the presence and severity of tricuspid regurgitation. Am J Cardiol 1999; 83:671-618.
132. Hillis LD, Cigarroa JE, Lange RA. Late revascularization reduces mortality in survivors of myocardial infarction. Cardiol Rev 1999; 7:144-148.
133. Lange RA, Cigarrroa JE, Hillis LD. Thrombolysis versus primary PTCA for acute myocardial infarction. Cardiol Rev 1999:7; 77-82.
134. Pitts WR, Lange RA. Platelet glycoprotein IIb/IIIa receptor blockade: lessening the risk of coronary interventions. Thromb Haem 1999; 82 (Suppl):136-138.
135. Hundley WG, Hamilton CA, Clarke GD, Hillis LD, Herrington DM, LangeRA, Applegate RJ, Thomas MA, Payne J, Link KM, Peshock RM. Visualization and functional assessment of proximal and middle left anterior descending coronary stenoses in humans with magnetic resonance imaging. Circulation 1999; 99:3248-3254.
136. Rapp AH, Lange RA. Acute Management of acute myocardial infarction. Family Practice Recertification 1999; 21:69-80.
137. Lange RA, Hillis LD. Transmyocardial laser revascularization. N Engl J Med 1999; 341:1075-1076.
138. Mayes CE, Cigarroa JE, Lange RA, Hillis LD. Percutaneous mitral balloon valvuloplasty. Clin Cardiol 1999; 22:501-503.
139. Brickner ME, Hillis LD, Lange RA. Adult congenital heart disease. First of two parts. N Engl J Med 2000:342; 256-263.
140. Brickner ME, Hillis LD, Lange RA. Adult congenital heart disease. Second of two parts. N Engl J Med 2000:342; 334-342.

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141. Saland K, Cigarroa JE, Lange RA, Hillis LD. Rotatational atherectomy. Cardiol Rev 2000; 8:174-179.
142. Hundley WG, Hillis LD, Hamilton CA, Applegate RJ, Herrington DM, Clarke GD, Braden GA, Thomas MS, Lange RA, Peshock RM, Link KM. Assessment of coronary arterial restenosis with phase contrast magnetic resonance measurements of coronary flow reserve. Circulation 2000; 101:2375-2381.
143. Wong SC, Sanborn T, Sleeper LA, Webb JG, Pilchik R, Hart D, Mejnartowicz S, Antonelli TA, Lange R, French JK, Bergman G, LeJemtel T, Hochman J. Angiographic findings and clinical correlates in patients with cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry. J Am Coll Cardiol 2000; 36:1077-1083.
144. Lange RA, Hillis LD. Cardiovascular complications of cocaine Use. N Engl J Med 2001; 345: 351-358.
145. Cannon CP, Weintraub WS, Demopoulos LA, Viari R, Frey MJ, Lakkis N, Neumann F-J, Robertson DH, DeLucca PT, DiBattiste P, Gibson M, Braunwald E TACTICS-TIMI 18 Investigators. Comparison of early invasive versus conservative strategies in patients with unstable angina and non-ST elevation myocardial infarction treated with the glycoprotein IIb/IIIa inhbitor tirofiban. N Engl J Med 2001; 344:1879-1887.
146. Rapp AH, Lange RA, Cigarroa JE, Keeley EK, Hillis LD. Relation of pulmonary arterial diastolic and mean pulmonary capillary wedge pressure in patients with and without pulmonary hypertension. Am J Cardiol 2001; 88: 823-824.
147. Rapp AH, Hillis LD, Lange RA, Cigarroa JE. Prevalence of coronary artery disease in patients with aortic stenosis with and without angina pectoris. Am J Cardiol 2001;87:1216-1217.
148. Rapp AH, Cigarroa JE, Lange RA, Keeley EC, Hillis LD. Hemodynamic characteristics and procedural outcome of patients with mitral stenosis and a depressed cardiac output. Am J Cardiol 2001; 88:1212-1213.

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149. Moliterno DJ, Yakubov SJ, DiBattiste PM, Herrmann HC, Stone GW, Macaya C, Neumann FJ, Ardissino D, Bassand JP, Borzi L, Yeung AC, Harris KA, Demopoulos LA, Topol EJ; TARGET investigators. Outcomes at 6 months for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularization with stent placement: the TARGET study. Lancet 2002; 360: 355-360.
150. Lange RA, Hillis LD. Reperfusion therapy in acute myocardial infarction. N Engl J Med 2002; 346:954-55.
151. Saland KE, Hillis LD, Lange RA, Cigarroa JE. Influence of morphine sulfate on cocaine-induced coronary vasoconstriction. Am J Cardiol 2002;90: 810-811.
152. Lange RA, Hillis LD. Cardiology patient pagers. Diagnostic cardiac catheterization. Circulation. 2003; 107:e111-e113.
153. Casserly IP, Topol EJ, Jia G, Lange RA, Hamm C, Meier B, DiBattiste PM, Lakkis N, Chew DP, Stone GW, Cohen DJ, Moliterno DJ. Effect of abciximab versus tirofiban on activated clotting time during percutaneous intervention and its relation to clinical outcomes--observations from the TARGET trial. Am J Cardiol. 2003; 92:125-129
154. Lange RA, Hillis LD, et al. Antiplatelet therapy for ischemic heart disease. N Engl J Med 2004; 350:277-280.
155. Nguyen K, Cigarroa JE, Lange RA, Hillis LD, Keeley EC. Presence and extent of angiographic coronary narrowing in patients with left bundle branch block referred for coronary angiography Am J Cardiol 2004;93:1426-1427.
156. Lange RA, Cigarroa JE, Hillis LD. Theodore E. Woodward award: cardiovascular complications of cocaine use. Trans Am Clin Climat Assn. 2004;115:99-114.
157. Stauffenberg MT, Lange RA, Hillis LD, Cigarroa J, Hsu RM, Devaraj S, Jialal I. Hyperhomocysteinemia measured by immunoassay: a valid measure of coronary artery atherosclerosis. Arch Pathol Lab Med 2004; 128:1263-1266.

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158. Addo T, Keeley EC, Cigarroa JE, Lange RA, DeLemos JA, Dobbins RL, McGuire DK. Effect of glucose-insulin-potassium infusion on plasma free fatty acid concentrations in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction. Am J Cardiol 2004; 94:1288-1289.
159. Lange RA, Hillis LD. Acute pericarditis. N Engl J Med 2004; 351:2195-2202.
160. Lange RA, Hillis LD. Concurrent antiplatelet and fibrinolytic therapy. New Engl J Med 2005; 352:1248-1250.
161. Michos ED, Ardehali R, Blumenthal RS, Lange RA, Hossein A. Aspirin and clopidogrel resistance; a review. Mayo Clin Proceed 2006; 81:518-526.
162. Lange RA, Hillis LD. Dobutamine stress echocardiography in patients with lowgradient aortic stenosis. Circulation 2006; 113:1718-1720.
163. Hillis LD, Lange RA. Myocardial infarction and the open-artery hypothesis. N Engl J Med 2006; 355: 2475-2477.
164. Lange RA. Cardiovascular biomarkers: Pathophysiology and disease management (book review). N Engl J Med 2006; 355:2796-2797.
165. Musunuru K, Kral BG, Blumenthal RS, Fuster V, Campbell CY, Gluckman TJ, Lange RA, Topol EJ, Willerson JT, Desai MY, Davidson MH, Mora S. The use of high sensitivity C-reactive protein in clinical practice. Nature Clin Practice Cardiovasc Med 2008; 5:621-635.
166. Ahmed S, Lange RA, Hillis LD. Inaccuraries of oximetry in identifying the location of intracardiac left-to-right shunting in adults. Am J Cardiol 2008; 101:245-247.
167. Baughman KL, Duffy FD, Eagle KA, FAxon DP, Hillis LD, Lange RA. Task force 1: training in clinical cardiology. J Am Coll Cardiol 2008; 51:339-348.
168. Lange RA, Lindsey ML. HDL cholesterol levels and cardiovascular risk: acCETPing the context. Eur Heart J 2008; 29:2708-2709.

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169. Arbab-Zadeh A, Levine BD, Trost J, Lange RA, Keeley EC, Hillis LD, Cigarroa JE. The effect of hypoxemia on coronary arterial dimensions in subjects with and without coronary artery disease. Cardiology 2009; 113:149-154.
170. Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, Lardo AC, Lai S, Steenbergen S, Gerstenblith G, Lange R, Marbán E. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived celss in porcine ischemic myocardium. Circulation 2009; 120:1075-1083.
171. Lawal L, Lange R, Schulman S. Acute myocardial infarction in two young women without significant risk factors. J Invasive Cardiol 2009; 21:E3-E5.
172. Hillis LD, Lange RA. Optimal management of acute coronary syndromes. N Engl J Med 2009; 360:2237-2240.
173. Lange RA, Hillis LD. Coronary revascularization in context. N Engl J Med 2009; 360:1024-1026.
174. Lange RA, Hillis LD. Sudden death in cocaine users. Eur Heart J 2010; 31:271273.
175. Lange RA, Hillis LD. Second generation drug-eluting coronary stents. N Engl J Med 2010; 362:1728-1730.
176. Arbab-Zadeh A, Texter J, Ostbye KM, Kitagawa K, Brinker J, George RT, Miller JM, Trost JC, Lange RA, Lima JAC, Lardo AC. Quantification of lumen stenoses with known dimensions by conventional angiography and computed tomography: implications of using conventional angiography as gold standard. Heart 2010; 96:1358-1363.
177. Muscogiuri G, Sorice G, Tripathy D, Chavez A, Lange R, Folli F. Medical therapy of aortic aneurysms. A pathophysiology-based approach. Curr Vasc Pharmacol 2011;9:572-584.
178. Trost JC, Lange RA. Treatment of acute coronary syndrome (ACS). Part 1: nonST segment elevation ACS. Crit Care Med 2011;39:236-235.

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179. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2011;58:25502583.
180. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention. Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124:2574-2609.
181. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the Society for Coronary Angiography and Interventions. Circulation 2011;124:e574-651.
182. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the Society for Coronary Angiography and Interventions. J Am Coll Cardiol 2011;58:e44-122.
183. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guidelines for coronary artery bypass graft surgery: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124:e652-735.

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184. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guideline for coronary artery bypass graft surgery: Executive Summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2011;58:2584-2614.
185. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guideline for coronary artery bypass graft surgery: Executive Summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124:2610-2642.
186. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guidelines for coronary artery bypass graft surgery: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2011;58:e123-210.
187. Lange RA, Hillis LD. The hazards of comparative effectiveness when we can't effectively compare. JACC Cardiovasc Interv 2011;4:1028-1029.
188. Turer AT, Addo TA, Martin JL, Sabatine MS, Lewis GD, Gerszten RE, Keeley EC, Cigarroa JE, Lange RA, Hillis LD, de Lemos JA. Myocardial ischemia induced by rapid atrial pacing causes troponin T release detectable by a highly sensitive assay: insights from a coronary sinus sampling study. J Am Coll Cardiol 2011;57:2398-2405.

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189. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the Society for Coronary Angiography and Interventions. Cathet Cardiovasc Interv 2012;79:453-495.
190. Levine GN, Steinke EE, Bakaeen FG, Bozkurt BM, Cheitlin MD, Conti JB, Foster E, Kloner RA, Lange RA, Lindau S, Maron B, Moser DK, Ohman EM, Seftel AD, Stewart WJ. Sexual activity and cardiovascular disease: A Scientific Statement From the American Heart Association. Circulation 2012;125:10581072.
191. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guideline for coronary artery bypass graft surgery: Executive Summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg 2012;143:4-34.
192. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guideline for coronary artery bypass graft surgery: Executive Summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Anesth Analg 2012;114:11-45.
193. DeLeon KY, de Castro Bras L, Lange RA, Lindsey ML. Extracellular matrix proteomics in cardiac ischemia/reperfusion: The search is on. Circulation 2012;125:746-748.
194. Lindsey ML, Weintraub ST, Lange RA. Using extracellular matrix proteomics to understand left ventricular remodeling. Circ Cardiovasc Genet 2012;5:o1-7.
195. Trost JC, Lange RA. Treatment of acute coronary syndrome (ACS). Part 2: ST segment elevation MI. Crit Care Med 2012;40:1939-1945.

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196. Lange RA. Coronary angiography is not picture perfect for determining perioperative MI pathophysiology. Cathet Cardiovasc Interv 2012;80:777-778.
197. Lange RA. Confidence in ASD occlude devices is eroding. Cathet Cardiovasc Interv 2012;80:175-176.
198. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI Guideline for percutaneous intervention. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the Society for Coronary Angiography and Interventions. Cathet Cardiovasc Interv 2013;82:e266-355.
199. Blankenship JC, Marshall JJ, Pinto DS, Lange RA, Bates ER, Holper EM, Grines CL, Chambers CE. Effect of percutaneous coronary intervention on quality of life: A consensus statement from the Society for Cardiovascular Angiography and Interventions. Catheter Cardiovasc Interv 2013;81:243-250.
200. Lange RA. Preoperative risk assessment with cardiac CT: all dressed up and nowhere to go. J Am Coll Cardiol 2013;61:669-671.
201. Lange RA. Can you predict what happens when EuroSCORE weds biomarker? J Am Coll Cardiol 2013;61:682-684.
202. Lange RA, Hillis LD. The duel between dual antiplatelet therapies. N Eng J Med 2013;368:156-157.
203. Patterson NL, Iyer RP, Bras LDC, Li YJ, Andrews T, Aune G, Lange RA, Lindsey. Using proteomics to uncover extracellular matrix interactions during cardiac remodeling. Proteomics Clin Appl 2013;7:516-527.
204. Lange RA, Hillis LD. JAMA Clinical Challenge. JAMA 2014 (in print).
205. Levine GN, Allen K, Braun L, Christian H, Friedmann E, Taubert KA, Thomas SA, Wells DL, Lange RA. Pet ownership and cardiovascular risk; a scientific statement from the American Heart Association. Circulation 2013; 127:23532363.

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206. Andrews TG, Lindsey ML, Lange RA, Aune GJ. Cardiac assessment in pediatric mice: strain analysis as a diagnostic measurement. Echocardiography 2014; 31:375-384.
207. Draeger HT, Assassi S, Sharif R, Gonzalez EB, Harper BE, Arnett FC, Manzoor M, Lange RA, Mayes MD. Fascicular block: a predictor of mortality in early systemic sclerosis. PLoS One 2013; 8:e78808.
208. Narang N, Thibodeau J, Levine BD, Gore MO, Ayers CR, Lange RA, Cigarroa JE, Turer AT, de Lemos JA, McGuire DK. Inaccuracy of estimated resting oxygen uptake in the clinical setting. Circulation 2014;129:203-210.
209. Lange RA, Levine GN. Sexual activity and ischemic heart disease. Curr Cardiol Rep 2014;16:445-453.
210. Nguyen N, Zhang X, Wu C, Lange RA, Chilton RJ, Lindsey ML, Jin Y-F. Integrative computational and experimental approaches to establish a postmyocardial infarction knowledge map. PLoS Comput Biol 2014; 10(3): e1003472. doi:10.1371/journal.pcbi.1003472.
211. Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ. The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure. Am J Physiol Heart Circ Physiol. 2014 Nov 15; 307:H1379-389.
212. Ma Y, de Castro Bras LE, Toba H, Iyer RP, Hall M, Winniford M, Lange RA, Tyagi S, Lindesy ML. Myofibroblasts and the extracellular matrix network in post-mocardial infarction cardiac remodeling. Eur J Physiol 2014; 466:1113-1127.
213. Richards JR, Derlet RW, Albertson TE, Horowitz BZ, Lange RA. Methamphetamine, "bath salts," and other amphetamine-related derivatives: progressive treatment update. Enliven: Toxicol Allied Clin Pharmacol 2014; 1: 001.
214. Finn SD, Blankenship JC, Alexander KP, Bittl JA, Byrne JG, Fletcher BJ, Fonarow GC, Lange RA, et al. 2014 ACC/AHA/AATS/PCNA/SCAI/STS Focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease. JACC 2014, doi: 10.1016/j.jacc.2014.07.017.

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215. Lindsey ML, Mayr M, Gomes AV, Delles C, Arrell K, Murphy AM, Lange RA, Costello CE, Yu-Fang , Laskowitz DT, Sam F, Terzic A, Van Eyk J, Srinivas PR. The transformative impact of proteomics on cardiovascular disease and health. Circulation 2015; 132:852-872.
216. Lindsey ML. DeLeon-Pennell KY, Zamilpa R, Zouein F, Bratton D, Flynn ER, 2 Cannon PL, Tian Y, Jin Y-F, Lange RA, Fields GB, Iyer PR, de Castro Brás LE. A novel collagen matricryptin reduces left ventricular dysfunction postmyocardial infarction by preserving left ventricular geometry and integrity. JACC 2015; 66: 1364-1374.
217. Richards, JR, Albertson TE, Darlet RW, Lange RA, Olson KR, Horowitz BZ. Treatment of toxicity from amphetamines, related derivatives, and analogues: A systematic clinical review. Drug Alcohol Depend. 2015; 150:1-13.
218. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Ting HH. 2015 Focused update on primary PCI for patients with STEMI: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 2016; 133:1135-47.
219. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Ting HH. 2015 Focused update on primary PCI for patients with STEMI: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2016; 67:1235-50.

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220. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Ting HH. 2015 Focused update on primary PCI for patients with STEMI: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cathet Cardiovasc Interv 2016; 87:1001-19.
221. Levine GN, Bates ER, Bittl J, Brindis R, Lange RA, Mack M, Mauri L, Mehran R, Mukherhee D, Sabatine M, Smith P, Smith S. ACC/AHA Focused update on duration of dual antiplatelet therapy in patients with coronary artery disease. An update of the 2011 ACC/AHA/SCAI guideline for PCI, the 2011 ACC/AHA guideline For CABG, the 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for SIHD, the 2013 ACC/AHA guideline for STEMI, the 2014 ACC/AHA guideline for NSTE-ACS, and the 2014 ACC/AHA perioperative guideline. Circulation 2016; 134:123-55.
222. Levine GN, Bates ER, Bittl J, Brindis R, Lange RA, Mack M, Mauri L, Mehran R, Mukherhee D, Sabatine M, Smith P, Smith S. ACC/AHA Focused update on duration of dual antiplatelet therapy in patients with coronary artery disease. An update of the 2011 ACC/AHA/SCAI guideline for PCI, the 2011 ACC/AHA guideline For CABG, the 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for SIHD, the 2013 ACC/AHA guideline for STEMI, the 2014 ACC/AHA guideline for NSTE-ACS, and the 2014 ACC/AHA perioperative guideline. JACC 2016; 68:1082-1115.
223. Levine GN, Bates ER, Bittl J, Brindis R, Lange RA, Mack M, Mauri L, Mehran R, Mukherhee D, Sabatine M, Smith P, Smith S. ACC/AHA Focused update on duration of dual antiplatelet therapy in patients with coronary artery disease. An update of the 2011 ACC/AHA/SCAI guideline for PCI, the 2011 ACC/AHA guideline For CABG, the 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for SIHD, the 2013 ACC/AHA guideline for STEMI, the 2014 ACC/AHA guideline for NSTE-ACS, and the 2014 ACC/AHA perioperative guideline. J Thor Cardiovasc Surg 2016; 152:1243-1275.
224. Richards JR, Lange RA. Labetalol and cardiovascular consequences of cocaine use (Letter to the Editor). Trends in Cardiovasc Med 2016; 26:202-203.

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225. Richards JR, Garber D, Laurin EG, Albertson TE, Derlet RW, Amsterdam EA, Olson KR, Ramoska EA, Lange RA. Treatment of cocaine cardiovascular toxicity: a systematic review. Clin Toxicol 2016; 54;345-364.
226. Richards JR, Lange RA. Acute toxicity from topical cocaine for epistaxis: treatment with labetalol. Ann Emerg Med 2017; 52:311-313.
227. Richards JR, Lange RA. Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol. Am J Emerg Med 2017; 35:519.e1-e4.
228. Richard JR, Lange RA, Ramoska EA, Sand IC, Heusch G. Beta-blockers, cocaine and the unopposed alpha-stimulation phenomenon. J Cardiovasc Pharmacol Ther. 2017; 22:239-249.
229. Allen KB, Yuh DD, Schwartz SB, Lange RA, Hopkins R, Bauer K, Marders J, Donayre JD, Milligan N, Wentz C. Nontuberculous mycobacterium infections associated with heater-cooler devices used during cardiothoracic surgery: an emerging public health concern. Ann Thorac Surg 2017; 104:1237-42.
230. Lange RA, Brickner ME. Improving survival in patients with Eisenmenger syndrome; are we any closer. Circulation 2017; 135:1441-3.
231. Richards JR, Laurin EG, Tabish N, Lange RA. Response to beta-blocker in acute cocaine toxicity: is it safe. J Emerg Med 2017; 53:571-572.
232. Agrawal H, Lange R, Montanez R, Wali S, Mohammad KO, Kar S, Teleb M, Mukherjee D. The role of percutaneous coronary intervention in the treatment of chronic total occlusions: rationale and review of the literature. Curr Vasc Pharmacol 2018. Jan 16. doi: 10.2174/1570161116666180117100635. [Epub ahead of print]
233. Levine GN, Lange RA, Bairey-Merz CN, Davidson RJ, Jamerson K, Mehta PK, Michos ED, Norris K, Ray IB, Saban KL, Shah T, Stein R, Smith SC Jr; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; and Council on Hypertension. Meditation and cardiovascular risk reduction: a scientific statement from the American Heart Association. J Am Heart Assoc 2017; 6: pii: e002218. doi: 10.1161/JAHA.117.002218.

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234. Menezes A, Atkinson T, Lange RA, Cigarroa J. The evolving paradigm concerning antiplatelet and anticoagulation therapy after percutaneous coronary intervention (in preparation).
235. Andrews TG, Lindsey ML, Lange RA, Aune GJ. Cardiac strain quantifies doxorubicin-induced cardiotoxicity in pediatric mice. Echocardiography 2018 (submitted).
236. Andrews TG, Lindsey ML, Lange RA, Aune GJ. Acute doxorubicin exposure in pediatric mice directly induces the DNA damage response and collagen I production in cardiac fibroblasts. J Mol Cell Cardiol 2018 (submitted).
237. Agrawal H, Lange RA, Montanez R, Wali S, Mohammad KO, Kar S, Teleb M, Mukherjee D. The role of percutaneous coronary intervention in the treatment of chronic total occlusions: rationale and review of the literature. Curr Vasc Pharmacol. 2019; 17:278-290.
238. Brower RD, Hogg T, Francis M, Lange RA, Ogden PE. Snapshots of medical student education in the United States and Canada. Academic Medicine 2020 (submitted).
Book Chapters
1. Lange RA, Hillis LD. The evaluation of cardiovascular function. In: Pepine CJ (ed). "Diagnostic and Therapeutic Cardiac Catheterization." Baltimore: Williams and Wilkins, pp 346-378, 1989.
2. Hillis LD, Lange RA, Cigarroa RG. Cardiac catheterization. In Kloner RA (ed). "The Guide to Cardiology." New York: Wiley Medical, pp 113-138, 1989.
3. Firth BG, Lange RA. Pathophysiology and management of primary pump failure. In: Rahimtoola SH and Gersh BG (eds). "Management of Acute Myocardial Infarction." New York: Elsevier Science Publishing Company, 1990, pp 218-235.
4. Lange RA, Flores ED, Hillis LD. Restenosis after balloon angioplasty. In: Creger WP, Coggins CH, Hancock EW (eds). "Annual Review of Medicine." Palo Alto, CA: Annual Reviews Inc, 1991, vol 42, pp 127-132.

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5. Flores ED, Lange RA, Hillis LD. Triage and management strategies for acute myocardial infarction: Roles of the community and referral hospitals. In: Anderson JL (ed). "Modern Management of Acute Myocardial Infarction in the Community Hospital." New York: Marcel Dekker Inc, 1991, pp 65-86.
6. Hillis LD, Lange RA, Wells PJ, Winniford MD. Manual of Clinical Problems in Cardiolog (fourth edition). Little, Brown, & Co., Boston, 1992 (authored 32 chapters)
7 Lange RA, Hillis LD. Assessment of cardiovascular function. In: Pepine CJ, Hill CJ, Lambert CR (ed). "Diagnostic and Therapeutic Cardiac Catheterization." Baltimore: Williams and Wilkins, 1994, pp 394-429.
8. Hillis LD, Lange RA, Wells PJ, Winniford MD. Manual of Clinical Problems in Cardiology (fourth edition). Little, Brown, & Co., Boston, 1994 (authored 34 chapters)
9. Willard JE, Lange RA, Hillis LD. Cardiac Catheterization. In Kloner RA (ed). "The Guide to Cardiology." New York: Wiley Medical, 1995, pp 145-164.
10. Lange RA, Hillis LD. Cardiac effects of electrolyte disorders, drugs, and toxins. In: Braunwald EB, Crawford MH, Goldhaber SZ, Freedom R, Brown V, Colucci W, Beller G, Hollenberg NK, Rahimtoola SH, Creager M, Califf R, Abelmann WH, Scheinman M (eds). "Atlas of Heart Diseases." Philadelphia: Current Medicine, pp 8.1-8.21, 1996.
11. Lange RA, Hillis LD. Diagnostic and Therapeutic Catheterization. Chapter 94 in Textbook of Internal Medicine, third edition, edited by Kelly WN, LippincottRaven, Philadelphia and New York, pp 528-538, 1997.
12. Lange RA, Keely EC, Daniel WC, Hillis LD. Cardiomyopathy. In Conn RB, Borer WZ, Snyder JW (eds). "Current Diagnosis 9." WB Saunders Co, pp 436441, 1997.
13. Lange RA, Hillis LD. Assessment of cardiovascular function. In: Pepine CJ, Hill CJ, Lambert CR (ed). "Diagnostic and Therapeutic Cardiac Catheterization." Baltimore: Williams and Wilkins, 1998, pp 480-515.

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14. Lange RA, Hillis LD. Cardiac catheterization and hemodynamic assessment. In: Topol EJ (ed). "Textbook of Cardiovascular Medicine." Philadelphia: LippincottRaven, 1998, pp 1957-1976.
15. Lange RA, Hillis LD. Cardiac catheterization and hemodynamic assessment. In: Topol EJ (ed). "Comprehensive Cardiovascular Medicine." Philadelphia: Lippincott-Raven, 1998, pp 2231-2249.
16. Lange RA, Hillis LD. Aggressive vs conservative therapy in unstable angina. In: Uretsky BF, Runge M (eds). "Cardiology Clinics of North America." Philadelphia; WB Saunders, 1999, pp 387-99.
17. Lange RA, Hillis LD. Diagnostic and Therapeutic Catheterization. Chapter 87 in Humes Hd (ed) "Kelleys' Textbook of Internal Medicine, Fourth Edition," Lippincott-Raven, Philadelphia and New York, 2000, 623-634.
18. Lange RA, Hillis LD. Cardiac catheterization and hemodynamic assessment. In: Topol EJ (ed). "Comprehensive Cardiovascular Medicine." Second Edition." Philadelphia: Lippincott-Raven, 2002, pp 2231-2250.
19. Lange RA. Medical Treatment of Chronic Ischemic Heart Disease. ACC-SAP, American College of Cardiology, 2002.
20. Hillis LD, Lange RA, Page R, Winniford MD. Manual of Clinical Problems in Cardiology (sixth edition). Philadelphia; Lippincott-Raven, Boston, 2002 (authored 35 chapters).
21. Lange RA, Hillis LD. Cardiac catheterization and hemodynamic assessment. In: Topol EJ (ed). "Textbook of Cardiovascular Medicine. Second Edition." Philadelphia: Lippincott-Raven, 2002, pp 1651-1664.
22. Rapp AH, Lange RA Hillis LD. Cocaine and Other Environmental Causes of Acute Coronary Syndromes. In Theroux P (ed). "Acute Coronary Syndromes. A Companion to Braunwald's Heart Disease." Philadelphia; W.B. Saunders, 2003, pp 594-600.
23. Lange RA. Priestly Trust. In "Stroke As Metamorphosis." R Patton Howell, Boise; "Teas Road Press, 2003.

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24. Benjamin IJ, Lange RA, Hillis LD. Alcohol and Substance Abuse In: Andreoli T, Carpenter CC JR, Griggs RC, and Loscalzo J. (eds) "Cecils Essentials of Medicine. Sixth Edition." Philadelphia; W.B. Saunders, 2004, pp1109-1121.
25. Lange RA, Hillis LD. Toxins and The Heart In: Zipes DP, Libby P, Bonow RO and Braunwald E (eds) "Braunwald's Heart Disease: A Textbook of Cardiovascular Disease. Seventh Edition." Philadelphia; Elsevier Saunders, 2004, pp 1731-40.
26. Lange RA, Hillis LD. Valvular Heart Disease In; Wachter RM, Goldman L, Hollander H. (eds) "Hospital Medicine. Second Edition." Lippincott Williams & Wilkins, Philadelphia, 2005, Chapter 41, pp 381-391.
27. Gluckman TJ, Lange RA, Blumenthal RS. Postoperative therapies to reduce longterm cardiovascular risk. In: The Johns Hopkins Manual of Cardiothoracic Surgery. New York, McGraw-Hill, New York, 2007, Chapter 24, pp 413-428.
28. Frey PF, Yang EH, Ardehali H, Mudd JO, Waters R, Cheng A, Lange RA. Acute Coronary Syndromes 2004. In: "The Osler Medical Handbook. Second Edition." Philadelphia; Mosby, 2006, 86-102.
29. Lange RA, Hillis LD. Cardiac Catheterization and Hemodynamic Assessment. In: Topol EJ (ed). "Textbook of Cardiovascular Medicine. Third Edition." Philadelphia: Lippincott-Raven, 2006, pp 1243-1257.
30. Lange RA, Hillis LD. Anatomy and Physiology In: Mukherjee D, Cho L, Moliterno D (eds). "900 Questions: An Interventional Cardiology Board Review." Philadelphia: Wolters Kluwer/Lippincott, Williams & Wilkins, 2007, Chapter 2, pp 6-11.
31. Lange RA, Hillis LD. Toxins and The Heart In: Zipes DP, Libby P, Bonow RO and Braunwald E (eds) "Braunwald's Heart Disease: A Textbook of Cardiovascular Disease. Eighth Edition." Philadelphia; Elsevier Saunders, 2007, 1805-1814.
32. Lange RA. Pericardial Disease, In: Miller RG, Ashar BH, Sisson SD (eds) "Johns Hopkins Internal Medicine Board Review 2008-2009, Second Edition." Philadelphia: Mosby Elsevier, 2007, Chapter 61, pp 61-66.

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33. Lange RA, Hillis LD. Coronary Heart Disease. In: Andreoli T, Carpenter CC JR, Griggs RC, and Loscalzo J. (eds) "Cecils Essentials of Medicine. Seventh Edition." Philadelphia; W.B. Saunders, 2007, Chapter 9, 97-117.
34. Lange RA, Hillis LD. Alcohol and Substance Abuse. In: Andreoli T, Carpenter CC JR, Griggs RC, and Loscalzo J. (eds) "Cecils Essentials of Medicine. Seventh Edition." Philadelphia: W.B. Saunders, 2007, Chapter 133, 1179-1188.
35. Lange RA. Medical Treatment of Chronic Ischemic Heart Disease In: O'Gara Pt, Hirsch GA, Fang JC (eds). ACCSAP 7. Washington DC: American College of Cardiology; 2009. p. 11.4.1 - 11.4.9.
36. Lange RA, Hillis LD, Bailey SR. Introduction to Cardiac Catheterization In: Coronary & Peripheral Angiography and Interventional Procedures. Mukherjee D, Bates ER, Roffi M, Moliterno DJ (eds). London: Informa Healthcare; 2010, Chapter 1, 1-12.
37. Lange RA, Hillis LD. Alcohol and Substance Abuse. In: Andreoli T, Carpenter CC JR, Griggs RC, and Loscalzo J. (eds) "Cecils Essentials of Medicine, Eighth Edition." Philadelphia: WB Saunders, 2010, Chapter 135, 1220-33.
38. Lange RA and Hillis LD. Chronic Stable Angina. In: Nabel EG, Antman KH, Fitz JG, Fox DA, Maguire J, Haynes RB, Henrich JB, Wolinsky JS. "ACP Medicine." Ontario: Decker Intellectual Properties; 2011, Chapter 9, 1-21.
39. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Rakel RE, Kellerman RD (eds). "Conn's Current Therapy 2011 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2011, 337-342.
40. Lange RA and Hillis LD. Cardiovascular Testing. In: DiPirio JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM (eds). "Pharmacotherapy: A Pathophysiologic Approach, Eighth Edition." New York: McGraw Hill; 2011, Chapter 17, 55-81.
41. Lange RA and Hillis LD. Acute Coronary Syndrome: Unstable Angina and NonST Elevation MI. In Goldman L, Schaefer AI (eds). "Cecil Medicine, 24th edition." Philadelphia: Elsevier; 2011. Chapter 72, 425-34.

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42. Lange RA and Hillis LD. Toxins and the Heart In: Bonow RO Mann DL, Zipes DP, Libby P and Braunwald E (eds). "Braunwald`s Heart Disease: A Textbook of Cardiovascular Medicine. Ninth Edition," Philadelphia: Elsevier Saunders; 2011, Chapter 73, 1628-1637.
43. Lange RA, Hillis LD. Anatomy and Physiology In: Mukherjee D, Cho L, Moliterno DJ (eds). "1001Questions: An Interventional Cardiology Board Review." Philadelphia: Lippincott, Williams & Wilkins, 2012, Chapter 2, 13-22.
44. Lange RA. Medical Treatment of Chronic Ischemic Heart Disease In: O'Gara Pt, Hirsch GA, Fang JC (eds). ACCSAP 8. Washington DC: American College of Cardiology; 2012, Chapter 7, 2.1-2.8.
45. Lange RA. History and Physical Exam. In: O'Gara Pt, Hirsch GA, Fang JC (eds). ACCSAP 8. Washington DC: American College of Cardiology; 2012, Chapter 3, 1.1-1.14.
46. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2012 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2012, 422-427.
47. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2013 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2013, 425-429.
48. Lange RA. Chronic Stable Angina. In: Levine GN. "Cardiac Secrets. Fourth Edition" Philadelphia, Mosby Elsevier, 2013, Chapter 16, 117-123.
49. Lange RA and Hillis LD. Cardiovascular Testing. In: DiPirio JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM (eds). "Pharmacotherapy: A Pathophysiologic Approach, Ninth Edition." New York: McGraw Hill; 2014, Chapter 1, 1-28 and eChapter 13.
50. Lange RA and Hillis LD. Chemical Cardiomyopathies In: Bonow RO Mann DL, Zipes DP, Libby P and Braunwald E (eds). "Braunwald`s Heart Disease: A Textbook of Cardiovascular Medicine. Tenth Edition," Philadelphia: Elsevier Saunders; 2014, Chapter 68, 1603-1612.

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51. DeLeon KY, Yabluchanskiy A, Winniford MD, Lange RA, Chilton RJ, Lindsey ML. Modifying Matrix Remodeling to Prevent Heart Failure In: Li R-K, Weisel Richard D (eds). "Cardiac Regeneration and Repair: Volume 1: Pathology and Therapies. First Edition," Kidlington, UK: Elsevier/Woodhead Publishing; 2014, Chapter 3, 41-60.
52. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2014 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2014, 431-436.
53. Rahnama-Moghadam S, Hillis LD, Lange RA. Chemical Toxins And The Heart. In: Meenakshisundaram R (ed). "Heart and Toxin." Philadelphia, Elsevier; 2015, Chapter 3, 75-132.
54. Ma Y, Iyer RP, de Casto Bras LE, Toba H, Yabluchanskiy A, Deleon-Pennell KY, Hall ME, Lange RA, Lindsey ML. Cross Talk Between Inflammation And Extracellular Matrix Following Myocardial Infarction In: Blanesteijn WM, Altara R (eds). "Inflammation in Heart Failure." Philadelphia, Elsevier; 2014, Chapter 4, 67-80.
55. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2015 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2015, 455-460.
56. Lange RA, Hillis LD. Alcohol and Substance Abuse. In: Andreoli T, Carpenter CC JR, Griggs RC, and Loscalzo J. (eds) "Cecils Essentials of Medicine, Ninth Edition." Philadelphia: WB Saunders, 2015, Chapter 126.
57. Qunibi WY, Lange RA, Henrich WL. Coronary Artery Disease And Sudden Death In Patients With End-Stage Renal Disease. In: Henrich WL (ed)." Principles and Practice of Dialysis (5th ed)" Philadelphia, PA: Lippincott, Williams & Wilkins; 2016. Chapter 17, 268-297.
58. Lange RA and Hillis LD. Acute Coronary Syndrome: Unstable Angina and NonST Elevation Myocardial Infarction. In Goldman L, Schaefer AI (eds). "Cecil Medicine, 25th edition." Philadelphia: Elsevier; 2015. Chapter 73, 432-440.

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59. Lange RA, Stable Ischemic Heart Disease. In Levine G (ed). "Illustrated Guide to Cardiovascular Disease." New Delhi: Jaypee Brothers Medical Publishers (P) LTD; 2015. Chapter 5, 86-99.
60. Lange RA Cardiovascular Testing. In: DiPirio JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM (eds). "Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition." New York: McGraw Hill; 2017, Chapter 11, p 21 and eChapter 11.
61. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2017 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2017. Chapter 28, 103-108.
62. Lange RA and Hillis LD. Drug and Toxin Induced Cardiomyopathies. In: Mann DL, Zipes DP, Libby P, Bonow RO,and Braunwald E (eds). "Braunwald`s Heart Disease: A Textbook of Cardiovascular Medicine. Eleventh Edition," Philadelphia: Elsevier Saunders; 2018 (in print).
63. Lange RA. Chronic Stable Angina. In: Levine GN. "Cardiac Secrets. Fifth Edition" Philadelphia, Elsevier, 2017, Chapter 15, 135-142.
64. Lange RA and Hillis LD. Congenital Heart Disease. In: Bope ET, Kellerman RD (eds). "Conn's Current Therapy 2018 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2018, Section 3, pages 106-111.
65. Lange RA, Hillis LD, Bailey SR. Introduction to Cardiac Catheterization In:.Mukherjee D, Bates ER, Lange, RA Roffi M, Moliterno DJ (eds). Cardiovascular Catheterization and Intervention. A Textbook of Coronary, Peripheral and Structural Heart Disease (second edition). Informa Healthcare, London, 2017 (in print).
66. Cigarroa JE, Lange RA. Anatomy and Physiology In: Mukherjee D, Chatterjee S, Cho L, Lange, RA, Moliterno D, (eds). 1111 Questions: An Interventional Cardiology Board Review (third edition). Philadelphia: Wolters Kluwer/Lippincott, Williams & Wilkins, 2017 (in preparation).

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67. Lange RA and Cigarroa JE. Congenital Heart Disease. In: Kellerman RD, Rakel DP (eds). "Conn's Current Therapy 2019 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2019, Section 3, pages 105-110.
68. Lange RA and Mukherjee D. Acute Coronary Syndrome: Unstable Angina and Non-ST Elevation Myocardial Infarction. In Goldman L, Schaefer AI (eds). "Goldman-Cecil Medicine, 26th edition." Philadelphia: Elsevier; 2020. Chapter 63, 379-388.
69. Lange RA and Cigarroa JE. Congenital Heart Disease. In: Kellerman RD, Rakel DP (eds). "Conn's Current Therapy 2020 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2020, Section 3, "Chapter 28, pages 108-113.
70. Lange RA and Cigarroa JE. Congenital Heart Disease. In: Kellerman RD, Rakel DP (eds). "Conn's Current Therapy 2020 (Expert Consult: Online and Print)." Philadelphia: Elsevier; 2021, submitted.
Web-Based "Book" Chapters
71. Basson CT, Lim LK, Vaughan CJ. Carney Complex. In: Pearlman JD, Talavera F, Sheridan FM, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated May 2007. Available at: http://www.emedicine.com/med/TOPIC2941.HTM.
72. Hilkert RJ, Yoo H. Aortic Regurgitation. In: Keane M, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2006. Available at: http://www.emedicine.com/med/TOPIC156.HTM.
73. Talano JV, Melek BH. Aortic Stenosis. In: Forker AD, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated May 2006. Available at: http://www.emedicine.com/med/TOPIC157.HTM.
74. Jha SH, Dave J, Desai K, Kocheril AG. Mitral Regurgitation. In: Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Feb 2006. Available at: http://www.emedicine.com/med/TOPIC1485.HTM.

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75. Nachimuthu S, Balasundaram K, Salazar HP. Mitral Stenosis. In: Prisant LM, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Jan 2007. Available at: http://www.emedicine.com/med/TOPIC1486.HTM.
76. Thakkar BV, Forker AD, Schussheim AE. Mitral Valve Prolapse. In: Pearlman JD, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Nov 2006. Available at: http://www.emedicine.com/med/TOPIC1484.HTM.
77. Ren X, Saavedra PJ, Cannistra LB. Pulmonic Regurgitation. In: Forker AD, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2006. Available at: http://www.emedicine.com/med/TOPIC1964.HTM.
78. Ren X, Saavedra PJ, Cannistra LB. Pulmonic Stenosis. In: Willis PW, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated May 2006. Available at: http://www.emedicine.com/med/TOPIC1965.HTM.
79. Mancini MC, Sheridan FM. Tricuspid Atresia. In: Willis PW, Talavera F, OudizRJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2006. Available at: http://www.emedicine.com/med/TOPIC2313.HTM.
80. Mancini MC, Sheridan FM. Tricuspid Regurgitation. In: Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Feb 2006. Available at: http://www.emedicine.com/med/TOPIC2314.HTM.
81. Mancini MC, Sheridan FM. Tricuspid Stenosis. In: Willis PW, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2006. Available at: http://www.emedicine.com/med/TOPIC2315.HTM.
82. Hanson I, Alfonso LC. Mitral regurgitation. In Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds) eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC1485.HTM.

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83. Thakkar BV, Forker AD, Schussheim AE. Mitral Valve Prolapse. In Pearlman JD, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC1484.HTM.
84. Ren X, Saavedra PJ, Cannistra LB. Pulmonic Stenosis. In Willis PW, Talavera F, Runge MS, Suleman A, Lange RA (eds) eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC1965.HTM.
85. Mancini MC. Tricuspid Atresia. In Willis PW, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC1965.HTM.
86. Mancini MC. Tricuspid Regurgitation. In Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC2314.HTM.
87. Mancini MC. Tricuspid Stenosis In Willis PW, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://www.emedicine.com/med/TOPIC2315.HTM.
88. Hilkert RJ, Yoo H. Aortic Regurgitation In Keane M, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2008. Available at: http://www.emedicine.com/med/TOPIC156.HTM.
89. Ren X, Saavedra PJ, Cannistra LB. Pulmonic Regurgitation. In Forker AD, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated. April 2008. Available at: http://www.emedicine.com/med/TOPIC1964.HTM.
90. Talano JV, Meleck BH. Aortic Stenosis In Forker AD, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2007. Available at: http://www.emedicine.com/med/TOPIC157.HTM.
91. Mancini M. Tricuspid Atresia. In Willis PW IV, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=158359.

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92. Mancini M. Tricuspid Regurgitation. In Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=158484.
93. Mancini M. Tricuspid Stenosis. In Willis PW IV, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated July 2008. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=158604.
94. Ren X, Cannistra LB. Pulmonic stenosis. In Wills PW IV, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Mar 2009. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=157737.
95. Dima C, Desser KB, Nachimuthu S, Balasundaram K. Mitral Stenosis. In Prisant LM, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Nov 2009. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=155724.
96. Hassan SA, Maria V, Kim H. Loeffler Endocarditis. In Deshmukh H, Talavera F, Runge MS, Suleman A, Lange (eds). eMedicine from WebMD. Updated Oct 2008. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=155340.
97. Basson CT, Kim LK, Vaughan CJ. Carney Complex. In Pearlman JD, Talavera F, Sheridan FM, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated March 2009. Available at: http://emedicine.medscape.com/article/160000overview.
98. Hanson I, Afonso LS. Mitral Regurgitation. In Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA. (eds). eMedicine from WebMD. Updated Jan 2010. Available at: http://progps1.emedicine.com/gps/userhome.gps?show=doc&docid=155618.
99. Ren X, Cannistra LB, Pulmonic Regurgitation. In Forker AD, Talavera F, Runge MS, Sulmen A, Lange RA. (eds). eMedicine from Web MD. Updated April 2010. Available at: http://emedicine.medscape.com/article/157639-overview

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100. Ren X, Foster E, Ryan EW. Libman Sacks Endocarditis. In Basson CT, Talavera F, Sheridan FM, Suleman A, Lange RA (eds). eMedicine from Web MD. Updated April 2010. Available at: http://emedicine.medscape.com/article/155230overview.
101. Dima C, Desser KB. Mitral Stenosis. In Prisant LM, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated June 2010. Available at: http://emedicine.medscape.com/article/155724-overview.
102. Wang SS. Aortic Regurgitation. In Keane M, Talavera F, Compton SJ, Sulmen A, Lange RA (eds). eMedicine from WebMD. Updated June 2010. Available at: http://emedicine.medscape.com/article/150490-overview.
103. McPherson JA. Aortic Stenosis. In Forker AD, Talavera F, Compton SJ, Sulmen A, Lange RA (eds). eMedicine from WebMD. Updated June 2010. Available at: http://emedicine.medscape.com/article/150638-overview.
104. Kanjanauthai S, Sharma GK. Mitral Valve. In Lange RA (ed). eMedicine from WebMD. Updated July 2010. Available at: http://emedicine.medscape.com/article/1878301-overview.
105. Ren X, Cannistra LB. Pulmonic Regurgitation. In Forker AD, Talavera F, Runge MS, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Aug 2010. Available at: http://emedicine.medscape.com/article/157639-overview.
106. Mancini MC. Tricuspid Regurgitation. In Keane M, Talavera F, Oudiz RJ, Suleman A, Lange RA (eds). eMedicine from WebMed. Updated Nov 2010. Available at: http://emedicine.medscape.com/article/158484-overview
107. Dima C, Desser KB. Mitral Stenosis. In Prisant LM, Talavera F, Compton SJ, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated Nov 2010. Available at: http://emedicine.medscape.com/article/155724-overview.
108. Shah-Khan FM, Singh NK, Nallamothu N, Marino T. In Lange RA (ed). Anticoagulants and Thrombolytics in Pregnancy. eMedicine from WebMD. Updated Jan 2011. Available at: http://emedicine.medscape.com/article/164069overview.

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109. Assadi R, Motabar A. Conduction System of the Heart. In Lange RA (ed). eMedicine from WebMD. Updated Jan 2011. Available at: http://emedicine.medscape.com/article/1922987-overview.
110. Assadi R, Motabar A. Nerves of the Heart. In Lange RA (ed). eMedicine from WebMD. Updated Jan 2011. Available at: http://emedicine.medscape.com/article/1923077-overview.
111. Barnett MA. Tricuspid Valve. In Lange RA (ed). eMedicine from WebMD (in press). Updated Jan 2011. Available at: http://emedicine.medscape.com/article/1923232-overview.
112. Mansi IA, Slim AM. Echocardiography. In Windle ML, Lange RA (eds). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1820912-overview
113. Assadi R, Motabar A, Hilliard AA. Percutaneous Mitral Balloon Valvuloplasty. In Windle ML, Lange RA (eds). eMedicine from WebMD. August 2011. Available at: http://emedicine.medscape.com/article/1839677-overview
114. Lin J. Bioprosthetic Heart Valve Replacement. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1971075-overview
115. Lin J. Cardiac Imaging Contrast. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1971009-overview
116. Lin J. Cardiac Imaging Isotopes. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1971031-overview
117. Lin J. Implantable Defibrillators. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1971119-overview

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118. Ren X. Libman-Sacks Endocarditis. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/155230overview
119. Lin J. MRI Safe Pacemakers. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1978229-overview
120. Lin J. Mechanical Heart Valve Repair. In Lange RA (ed). eMedicine from WebMD. Updated April 2011. Available at: http://emedicine.medscape.com/article/1971053-overview
121. Hanson I. Mitral Regurgitation. In Lange RA (ed). eMedicine from WebMD. Updated May 2011. Available at: http://emedicine.medscape.com/article/155618overview
122. Sovari AA. Transcutaneous Cardiac Pacing. In Lange RA (ed). eMedicine from WebMD. Updated May 2011. Available at: http://emedicine.medscape.com/article/98939-overview
123. Basson CT, Lim LK, Vaughan CJ. Carney Complex. In: Pearlman JD, Talavera F, Sheridan FM, Suleman A, Lange RA (eds). eMedicine from WebMD. Updated May 2007. Available at: http://emedicine.medscape.com/article/160000-overview
124. Robinett DA. External Cardioverter Defibrillators. In: Lange RA (ed). eMedicine from WebMD. June 2011. Available at: http://emedicine.medscape.com/article/1982648-overview.
125. Barnett MA, McPherson JA. Tricuspid Valve Anatomy. In: Lange RA (ed). eMedicine from WebMD. June 2011. Available at: http://emedicine.medscape.com/article/1923232-overview
126. Zenn MR. Laser Angiography Device. In: Lange RA (ed). eMedicine from WebMD. June 2011. Available at: http://emedicine.medscape.com/article/1986666-overview
127. Assadi R. Heart nerve anatomy. In: Lange RA (ed). eMedicine from WebMD. June 2011. Available at http://emedicine.medscape.com/article/1923077-overview

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128. Rodriguez JFB. Pulmonic valve anatomy. In: Lange RA (ed). eMedicine from WebMD. June 2011. Available at: http://emedicine.medscape.com/article/1923144-overview
129. Xiushui R, Aggarwal K, Balentine J, BEssman E, Lombardi DP, Mc Pherson JA, Nanda NC, Pearlman JD, Reddy HK, Setnik G, Singh VN, Steiner RM, Strom JA. Aortic Stenosis. In Brown DFM, Talavera F, Compton SJ, Lin EC, Lange RA (eds). eMedicine from WebMD. Updated July 2011. Available at: http://emedicine.medscape.com/article/150638-overview.
130. Shurmer SW. Coronary Drug Eluting Stent. In: Lange RA (ed). eMedicine from WebMD. August 2011. Available at: http://emedicine.medscape.com/article/1970984-overview.
131. Levine E. Electrocardiography. In Lange RA (ed). eMedicine from WebMD. August 2011. Available at: http://emedicine.medscape.com/article/1894014overview.
132. Bilal RH, O'Neill BR, Duncan AH. Sternotomy. Electrocardiography. In Lange RA (ed). eMedicine from WebMD. August 2011. Available at: http://emedicine.medscape.com/article/1894058-overview.
133. Mohamad TN, Fakhri HA, Thatia D. Cardiovascular Disease and Pregnancy. In Lange RA (ed). Medscape. Nov 2014 . Available at: http://emedicine.medscape.com/article/162004-overview
134. Bilal R. Sternotomy. eMedicine from WebMD. Updated October 20, 2011. Available at: http://emedicine.medscape.com/article/1894058-overview.
135. Bilal R. Coronary Artery Bypass Grafting. In Lange RA (ed). Medscape. Updated September 2012. Available at: http://emedicine.medscape.com/article/1893992overview.
136. Bhimji S. Vascular Access in Cardiac Catheterization and Intervention. In Lange RA (ed). Medscape. Dec 2015. Available at: http://emedicine.medscape.com/article/1894124-overview

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137. Acharjee S. Slipczuk L, Codolosa JN, Contreras JFC, Figueredo VM, Pressman GS. Mitral Annular Calcification. In Talavera F, Lange RA (ed). Medscape. June 2014. Available at: http://emedicine.medscape.com/article/1967024-overview.
138. Strimal W, Ayub B, Contractor T. Pericardial Effusion. In Lange RA (ed). Medscape. June 2016.
139. Spangler S, Gentles. Acute Pericarditis. In Lange RA (ed). Medscape. June 2016.
140. Yarlagadda C. Cardiac Tamponade. In Lange RA (ed). Medscape. June 2016.
141. Hanson I, Keane M. Mitral Regurgitation. In Lange RA (ed). Medscape. June 2016.
142. Ren X. Aortic Stenosis. In Lange RA (ed). Medscape. June 2016.
143. Wong S. Aortic Regurgitation. In Lange RA (ed). Medscape. June 2016.
144. Gyanendra, S. Atrial myxoma. In Lange RA (ed). Medscape. June 2019. Available at: https://emedicine.medscape.com/article/151362-overview
145. Pearlman J, Okada M. Aortitis. In Lange RA (ed). Medscape. July 2019 . Available at: https://emedicine.medscape.com/article/150755-overview
Books
1. Hillis LD, Lange RA, Wells PJ, Winniford MD. Manual of Clinical Problems in Cardiology (fourth edition). Little, Brown, & Co., Boston, 1992.
2. Hillis LD, Lange RA, Page R, Winniford MD. Manual of Clinical Problems in Cardiology (fifth edition). Little, Brown, & Co., Boston, 1994.
3. Hillis LD, Lange RA, Page R, Winniford MD. Manual of Clinical Problems in Cardiology (fifth edition). Lippincott-Raven, Boston, 2003.

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4. Mukherjee D, Bates ER, Lange, RA Roffi M, Moliterno DJ (eds). Cardiovascular Catheterization and Intervention. A Textbook of Coronary, Peripheral and Structural Heart Disease (second edition). Informa Healthcare, London, 2018.
5. Mukherjee D, Lange, RA, Chatterjee S, Cho L, Moliterno D (eds). 1133 Questions: An Interventional Cardiology Board Review (third edition). Philadelphia: Wolters Kluwer/Lippincott, Williams & Wilkins, 2018.
6. Mukherjee D, Lange RA (eds). Approach to Cardiovascular Medicine and Surgery. Wolters Kluwer/Lippincott, Williams & Wilkins, 2020 (in process).
Audio/Audiovisual Presentations
1. Lange RA. An update on hypertrophic cardiomyopathy. Audio-Digest Internal Medicine. Vol 52, issue 21, Nov 2005.
2. Lange RA. Weekly podcasts. JHH, 2005-current (first and longest running medical podcast, #1 listenership)
3. Lange, RA. Cardiology, Oakstone Medical Publishing, 2007-2008.
4. Advanced Directives (actor). UTHSCSA Video Production and The Center for Medical Humanities & Ethics.
5. Winner of The Warren Sturgis Motion Media Award and The Motion Media:Video Award of Excellence from BioImages 2010 Media Competition (http://www.bca.org/gallery/bioimages2010.html)
6. PodMed-Johns Hopkins Medicine's Weekly News Round-Up. YouTube 2010 at http://www.youtube.com/watch?v=0g7SiX9E5_E.
7. Evaluation of Second Generation Drug-Eluting Stents. ReachMD/ ACC, 2/2011 http://reachmd.com/xmradioseries.aspx?sid=37
Abstracts

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1. Lange RA, Jeffrey FMH, Nunnally RL, Malloy CR: Influence of amiloride and extracellular calcium on intracellular buffering capacity and H+ extrusion rate in the intact rat heart. Clin Res 35(3):A294, 1987.
2. Schaefer S, Lange RA, Kulkarni PV, Katz J, Jansen DE, Parkey RW, Willerson JT, Peshock RM: Nuclear magnetic resonance imaging of partial coronary artery occlusion. Clin Res 35(3):A324, 1987.
3. Lange RA, Jeffrey FMH, Nunnally RL, Malloy CR: Intracellular acidosis in the intact heart: influence of calcium on recovery of pH and mechanical function. Soc Magn Reson Med 1:514, 1987.
4. Schaefer S, Lange RA, Kulkarni PV, Katz J, Jansen DE, Parkey RW, Willerson JT, Peshock RM: Nuclear magnetic resonance imaging of partial coronary artery occlusion. Soc Magn Reson Med 1:329, 1987.
5. Lange RA, Jeffrey FMH, Nunnally RL, Malloy CR: Contribution of amiloride sensitive Na+-H+ exchange to the apparent buffering capacity in the intact rat heart. Circulation 76:IV-18, 1987.
6. Malloy CR, Jeffrey FMH, Klein DL, Lange RA, Babcock EE, Vaughan JT, Peshock RM, Nunnally RL: Single and double coil methods for 31P NMR spectroscopy of the human myocardium. Circulation 76:IV-245, 1987.
7. Nunnally RL, Babcock EE, Malloy CR, Lange RA, Klein DL, Vaughan JT: Difficulties with concentric surface coils for spatial localization of in vivo NMR spectroscopy. Radiology 165:154, 1987.
8. Lange RA, Moore DM, Cigarroa RG, Hillis LD. The use of pulmonary capillary wedge pressure to assess the severity of mitral stenosis: is a true left atrial pressure needed in these patients? J Am Coll Cardiol 13:146A, 1989.
9. Meidell RS, Gerard RD, Lange R, Hillis LD, Buja LM, Sambrook JF, Willerson JT. Experimental coronary thrombosis increases local coronary plasminogen activator expression. Clin Res 37:592A, 1989.
10 Lange RA, Cigarroa RG, Yancy CW, Willard JE, Popma JJ, Sills MN, Hillis LD. Cocaine-induced coronary vasoconstriction in man and its alleviation by alphaadrenergic blockade. Circulation 80:II-351, 1990.

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11 Lange RA, Cigarroa RG, Hillis LD. Cocaine-induced reduction in cross-sectional area of coronary artery stenoses in man: a quantitative assessment. Circulation 80:II-351, 1990.
12. McGhia AI, Lange RA, Kahn JK, Faber TL, Akers MS, Willerson JT, Corbett JR. Assessment of relative myocardial perfusion reserve in patients with maximal exercise Tc-99m MIBI gated tomography: correlations with quantitative coronary arteriography. Circulation 80:II-545, 1990.
13. Brogan WC, Lange RA, Kim AS, Moliterno DJ, Hillis LD. Alleviation of cocaine-induced coronary vasoconstriction by nitroglycerin. J Am Coll Cardiol 17:174A, 1991.
14. Brogan WC, Lange RA, Hillis LD. Limitations of the simplified formula for calculating valve area in patients with mitral stenosis. J Am Coll Cardiol 17:254A, 1991.
15. Brogan WC, Lange RA, Glamann DB, Hillis D. Prolonged coronary vasoconstriction after intranasal cocaine. Circulation 84:II-346, 1991.
16. Jacobsen TN, Lange RA, Converse RL, Obregon TM, Victor RG. Differential control of forearm and calf vascular resistance during intracoronary injection of ionic contrast material. Circulation 84:II-556, 1991.
17. Glamann DG, Boehrer JD, Lange RA, Willard JE, Brogan WC III, Eichhorn EJ, Grayburn PA, Anwar A, Hillis LD. A prospective study of the effect of coronary angioplasty on established late potentials after acute myocardial infarction. J Am Coll Cardiol 19:384A, 1992.
18. Moliterno DJ, Lange RA, Meidell RS, Willlard JE, Leffert CC, Boerwinkle EA, Gerard RD, Hobbs HH, Hillis LD. Relation of plasma lipoprotein(a) to infarct artery patency in survivors of myocardial infarction. Circulation 86:I-803, 1992.
19. Moliterno DJ, Leffert CC, Lange RA, Willard JE, Boerwikle EA, Hillis LD. Plasma lipoprotein(a) is not a risk factor for coronary atherosclerosis in blacks. Circulation 86:I-337, 1992.

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20. Negus BH, Willard JE, Hillis LD, Glamann DB, Landau C, Snyder RW, Lange RA. Alleviation of cocaine-induced coronary vasoconstriction in man with intravenous verapamil. Circulation 88:I-297, 1993.
21. Negus BH, Willard JE, Glamann DB, Landau C, Snyder RW, Hillis LD, Lange RA. Utility of routine cardiac catheterization in young, asymptomatic survivors of myocardial infarction. Circulation 88:I-60, 1993.
22. Jacobsen TN, Snyder RW II, Grayburn PA, Lange RA, Victor RG. Intranasal cocaine decreases sympathetic nerve activity in humans. Circulation 88:I-85, 1993.
23. Moliterno DJ, Willard JE, Lange RA, Negus BH, Boehrer JD, Glamann DB, Landau C, Rossen JD, Winniford MD, Hillis LD. Potentiation of cocaine-induced coronary vasoconstriction by cigarette smoking,. Circulation 88:I-254, 1993.
24. Hundley WG, Clarke GD, Landau C, Lange RA, Willard JE, Hillis LD, Peshock R. Determination of infarct artery patency by cine magnetic resonance imaging. Circulation 90:I-300, 1994.
25. Hundley WG, Lange RA, Lee HF, Landau C, Willard JE, Pfeiffer D, Peshock RM. Identification of significant left-to-right intracardiac shumts by velocityencoded, phase differnce, cine magnetic resonance imaging: A comparison with oximetry and indocyanine green dye. J Am Coll Cardiol 1994.
26. Daniel WC, Pirwitz MJ, Horton RP, Landau C, Glamann DB, Willard JE, Wells PJ, Hillis LD, Lange RA, Page RL. Electrophysiologic effects of cocaine in humans. PACE 1995.
27. Daniel WC, Lange RA, Willard JE, Landau C, Hillis LD. Effects of intracoronary cocaine on coronary arterial dimensions and flow. Circulation 92(Suppl I):I-531, 1995.
28. Hundley WG, Lange RA, Clarke GD, Meshack B, Payne J, Landau C, Sayad D, Willett D, Willard JE, Hillis LD, Peshock RM. Assessment of absolute coronary artery flow and flow reserve in humans with magnetic resonance imaging. Journal of the American College of Cardiology 27:4A, 1996.

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29. Johnston P, Sasano T, Mills K, Youssef A, Pittenger M, Lange R, Marbán E. Isolation, Expansion and Delivery of Cardiac Derived Stem Cells in a Porcine Model of Myocardial Infarction. Circulation 114_II-125, 2006.
30. Narang N, Lange RA. "Can VO2 be Accurately Estimated in a Contemporary Clinical Setting" for which you are a co-author has been accepted for presentation at the AHA QCOR conference this May in Atlanta.
31. Allen K, Lange RA. Nontuberculous Mycobacterium (NTM) Infections Associated with Heater-Cooler Devices (HCD) Used During Cardiothoracic Surgery: An Emerging Public Health Concern. Soc Thoracic Surgery 2016.


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