VT Symposium 2015 Brochure

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10th International Symposium on

VENTRICULAR
ARRHYTHMIAS:
Pathophysiology & Therapy
www.vtsymposium.com
Friday & Saturday
October 9-10, 2015
Hyatt at the Bellevue
200 South Broad Street
Philadelphia, PA 19102

A CME-CERTIFIED COURSE

Co-hosted by:

Hospital of the
University of Pennsylvania
The Mount Sinai Hospital
Co-sponsored with:

Course Directors
Francis Marchlinski, MD
David Callans, MD
Vivek Reddy, MD
Andre d’Avila, MD, PhD

10th International Symposium on

VE NT RICUL AR ARRHYT HMIAS:
Pathophysiology & Therapy
www.vtsymposium.com
A CME-certified Course

Friday & Saturday, October 9-10, 2015

Program Overview
The purpose of this educational activity is to provide a
current review of new information on the basic
pathophysiology of ventricular arrhythmias; to provide
an in-depth understanding of the various management
strategies that are currently being developed for the management of ventricular
arrhythmias in various disease states, including non-pharmacologic therapies such as
an implantable device therapy and advances in catheter ablation techniques.

Hosting Organizations
The 10th International Symposium on Ventricular Arrhythmias: Pathophysiology
& Therapy is hosted by the Department of Medicine, Division of Cardiology,
University of Pennsylvania Health System, Philadelphia, PA and the Division of
Cardiology, The Mount Sinai Hospital, New York, NY.

Target Audience
This course has been developed to meet the educational needs of electrophysiologists,
cardiologists and other physicians and associated professionals with an interest in the
pathophysiology and management of ventricular arrhythmias.

Program Objectives
1. Provide a current review of new information on the basic pathophysiology
of ventricular arrhythmias.
2. Provide an in-depth understanding of the various management strategies that are
currently being developed for the management of ventricular arrhythmias in
various disease states, including non-pharmacological therapies such as implantable
device therapy and advances in catheter ablation techniques.
At the conclusion of this symposium, participants should be able to:
• Describe the science critical to the understanding of ventricular arrhythmias and
treatment of ventricular arrhythmias including:
-The role of the autonomic nervous system in ventricular arrhythmogenesis.
-Biophysics of ablation.
-Anatomic substrate for ventricular tachycardia (VT).
• Understand the current status and future role for implantable cardioverterdefibrillators (ICD) in the management of sudden cardiac death.
• Describe the role of remote hemodynamic monitoring.
• Discuss the use of and techniques for ECGi, MRI in the EP lab, voltage guided
biopsy, high density mapping of VT circuits.
• Describe risk stratification and treatment including ablation, ICD, and
genetic testing in hypertrophic cardiomyopathy.
• Discuss strategies to improve treatment of patients with ventricular
arrhythmias and structural heart disease including “bail out” strategies after
failed catheter ablation.

Hyatt at the Bellevue
200 South Broad Street
Philadelphia, PA 19102
215-893-1234

• Understand the current state of the use of antiarrhythmic drug therapy for
ventricular arrhythmias.
• Identify techniques to improve ablation success for idiopathic arrhythmias
including use of advanced imaging.
• Describe the status of ongoing multicenter VT related trials and discuss
which questions need to be answered by trials in the future.

Accreditation
Physicians: The Perelman School of Medicine at the University of Pennsylvania
is accredited by the Accreditation Council for Continuing Medical Education
(ACCME) to provide continuing medical education for physicians.
Nurses: The Hospital of the University of Pennsylvania, Department of
Nursing Education, Innovation and Professional Development is an approved
provider of continuing nursing education by the PA State Nurses Association,
an accredited approver by the American Nurses Credentialing Center’s
Commission on Accreditation.

Designation of Credit
Physicians: The Perelman School of Medicine at the University of Pennsylvania
designates this live activity for a maximum of 18.25 AMA PRA Category 1
Credits™. Physicians should claim only the credit commensurate with the
extent of their participation in the activity.
Nurses: The Hospital of the University of Pennsylvania, Department of Nursing
Education, Innovation and Professional Development awards this activity
18.25 contact hours.
Certificates and Transcripts: A few days prior to the symposium, pre-registered
participants will receive an email containing directions, additional symposium
information and a link to the symposium pre-test, a short questionnaire that will be
used to gauge participant knowledge. After the symposium has concluded, all
participants will receive a follow-up email containing a link to the post-test,
symposium evaluation and request for credit. Once participants submit the request
for credit, the credit can be viewed on a transcript or a certificate can be printed by
logging onto www.penncmeonline.com once the conference concludes.

Disclosures
Perelman School of Medicine at the University of
Pennsylvania, Office of Continuing Medical Education,
adheres to the ACCME Standards for Commercial
Support. Faculty disclosure information will be made
available in the conference materials and syllabi. Faculty members are also expected
to disclose to participants any discussions of off-label and/or investigational uses of
pharmaceutical products during their presentations.

Registration Fees
Prior to September 6, 2015 the early registration fees for the 10th International
Symposium on Ventricular Arrhythmias: Pathophysiology & Therapy are
$525 for physicians, $525 for industry employees and $275 for all other healthcare
professionals, residents and fellows. On or after September 6, 2015 the registration
fees for the 10th International Symposium on Ventricular Arrhythmias:
Pathophysiology & Therapy are $600 for physicians, $600 for industry employees
and $350 for all other healthcare professionals, residents and fellows.
The registration fee includes tuition, a course booklet with access to presentations
online, continental breakfasts, breaks and lunches.
You may register online for the course by visiting www.vtsymposium.com and click
on CME Activities. You may also mail or fax your completed registration form
and payment. Please see the top of the registration form for mailing and faxing
information. All registrations will be confirmed in writing if your registration form
and fee are received by October 2, 2015.

Meeting Location and Parking
The 10th Annual International Symposium on
Ventricular Arrhythmias: Pathophysiology & Therapy
will take place at the Hyatt at the Bellevue,
200 South Broad Street, Philadelphia, PA 19102.
The hotel’s main number is 215-893-1234. Please visit the Hyatt website at
www.philadelphia.hyatt.bellevue.com for directions and additional information.
A block of rooms has been reserved at the Hyatt at the Bellevue at a special group
rate of $235 per night single/double occupancy. Taxes are 15.2% per room per night
and are subject to change. We recommend you make a reservation as soon as possible
since there are a limited number of rooms available. Please call the Bellevue at the
Hyatt reservations directly at 215-893-1234 or 1-800-GO-HYATT. Identify yourself
as a “Penn VT Symposium” participant. This limited room block is available until
September 18, 2015 or until the block is full.
The Hyatt at the Bellevue Philadelphia offers valet services and a self-parking
garage. Parking and associated fees are not included in the registration fee and
will not be validated.
For information on additional overnight accommodations or what to do or see
while you’re in Philadelphia, please go to www.gophila.com.

For VT Symposium Information Contact:
Carolyn Siwinski or Erica Zado
Hospital of the University of Pennsylvania
Tel: 215-662-6005 | Fax: 215-662-2879
Website: www.vtsymposium.com
Email: carolyn.siwinski@uphs.upenn.edu or
erica.zado@uphs.upenn.edu (Subject: VT Symposium)

Cancellation and Refund Policy
In order to process refunds for course withdrawals, cancellations must be received in
writing by October 2, 2015 (subject to a service charge equivalent to 10% of the
registration fee, but no less than $25.00). No refunds will be issued thereafter.
The University reserves the right to cancel or postpone any course due to unforeseen
circumstances. In the event of cancellation or postponement, the University will
refund registration fees but is not responsible for related costs or expenses to
participants, including cancellation fees assessed by hotels, airlines, and travel agencies.

Services for the Disabled If special arrangements are required for an individual with a disability to attend this meeting, please
contact the Office of Continuing Medical Education no later than October 2, 2015 at 215-898-6400.
Nondiscrimination Statement The University of Pennsylvania values diversity and seeks talented students, faculty, and staff from
diverse backgrounds. The University of Pennsylvania does not discriminate on the basis of race, sex, sexual orientation,
gender identity, religion, color, national or ethnic origin, age, disability, or status as a Vietnam Era Veteran or disabled veteran in the
administration of educational policies, programs or activities; admissions policies; scholarship and loan awards; athletic, or other
University administered programs or employment. Questions or complaints regarding this policy should be directed to
Executive Director, Office of Affirmative Action and Equal Opportunity Programs, 3600 Chestnut Street, Sansom Place East Suite 228,
Philadelphia PA 19104-6106 or 215-898-6993 (Voice) or 215- 898-7803 (TDD). www.upenn.edu/affirm-action

Sanjay Dixit, MD
University of Pennsylvania Health System
Philadelphia, PA

Jacob Koruth, MD
Mount Sinai Hospital
New York, NY

John Sapp, MD
QEII Health Sciences Center
Halifax, NS, Canada

Srinivas Dukkipati, MD
Mount Sinai Hospital
New York, NY

Andrew Krahn, MD
University of British Columbia
Vancouver, British Columbia

William Sauer, MD
University of Colorado School of Medicine
Aurora, CO

Francis Marchlinski, MD
University of Pennsylvania Health System
Philadelphia, PA

Kenneth Ellenbogen, MD
Medical College of Virginia
Richmond, VA

David Lin, MD
University of Pennsylvania Health System
Philadelphia, PA

David Callans, MD
University of Pennsylvania Health System
Philadelphia, PA

Andrew Epstein, MD
University of Pennsylvania Health System
Philadelphia, PA

Nassir Marrouche, MD
University of Utah Hospitals and Clinics
Salt Lake City, UT

Peter J. Schwartz, MD
Center for Cardiac Arrhythmias
of Genetic Origin
Milan, Italy

Vivek Reddy, MD
Mount Sinai Hospital
New York, NY

David Frankel, MD
University of Pennsylvania Health System
Philadelphia, PA

Barry Maron, MD
Minneapolis Heart Institute Foundation
Minneapolis, MN

Andre d’Avila, MD, PhD
Hospital Cardiologico
Santa Catarina, Brazil

Fermin Garcia, MD
University of Pennsylvania Health System
Philadelphia, PA

John Miller, MD
Indiana University Health
Indianapolis, IN

Faculty

Edward Gerstenfeld, MD
University of California San Francisco
San Francisco, CA

Marc Miller, MD
Mount Sinai Hospital
New York, NY

Roderick Tung, MD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA

Henry Halperin, MD, MA
Johns Hopkins Medical Center
Baltimore, MD

Andrea Natale, MD
St. David’s Medical Center
Austin, TX

Wendy Tzou, MD
University of Colorado School of Medicine
Aurora, CO

Gerhard Hindricks, MD
University of Leipzig Heart Center
Leipzig, Germany

Anjali Owens, MD
University of Pennsylvania Health System
Philadelphia, PA

Mathew Hutchinson, MD
University of Pennsylvania Health System
Philadelphia, PA

Eric Prystowsky, MD
The Care Group
Indianapolis, IN

Miguel Valderrabano, MD
Houston Methodist DeBakey Heart
& Vascular Center
Houston, TX

Pierre Jais, MD, PhD
Central Hospital University of Bordeaux
Bordeaux, France

Michael Riley, MD, PhD
University of Pennsylvania Health System
Philadelphia, PA

Mark Josephson, MD
Beth Israel Deaconess Medical Center
Boston, MA

Yoram Rudy, PhD
Washington University
St. Louis, MO

Suraj Kapa, MD
Mayo Clinic
Rochester, MN

Luis C. Sáenz, MD
Fundación Cardio Infantil-Instituto
de Cardiología
Bogotá, Colombia

Course Directors

Jesus Almendral, MD, PhD
Hospital Madrid Monteprincipe
Madrid, Spain
Elad Anter, MD
Beth Israel Deaconess Medical Center
Boston, MA
Samuel Asirvatham, MD
Mayo Clinic
Rochester, MN
Frank Bogun, MD
University of Michigan Health System
Ann Arbor, MI
Alfred Buxton, MD
Beth Israel Deaconess Medical Center
Boston, MA
Christian de Chillou, MD, PhD
University Hospital
Nancy, France
Paolo Della Bella, MD
Institute of Cardiology –
Centro Cardiologico
Milan, Italy
Timm Dickfeld, MD, PhD
University of Maryland Medical Center
Baltimore, MD

Josef Kautzner, MD, PhD
Institute for Clinical &
Experimental Medicine
Prague, Czech Republic

Pasquale Santangeli, MD
University of Pennsylvania Health System
Philadelphia, PA

Kalyanam Shivkumar, MD, PhD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA
William Stevenson, MD
Brigham & Women’s Hospital
Boston, MA
Gregory Supple, MD
University of Pennsylvania Health System
Philadelphia, PA

Marmar Vaseghi, MD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA
David Wilber, MD
Loyola University Medical Center
Maywood, IL
Fred Wittkampf, PhD
University Medical Center Utrecht
Utrecht, The Netherlands

AGENDA
Friday, October 9, 2015
6:45 – 7:25 AM
Registration and Continental Breakfast
7:25 – 7:30 AM
Welcome: Year 10 – A Decade
of Scientific Progress
Francis Marchlinski, MD

Saturday, October 10, 2015
10:45 – 11:00 AM
Is Stopping Amiodarone an
Achievable Goal of Ablation?
David Frankel, MD
11:00 – 11:20 AM Panel Discussion

3:00 – 3:15 PM
High Density Mapping of VT Circuits
Elad Anter, MD
3:15 – 3:30 PM
Fragmentation Mapping
Edward Gerstenfeld, MD

11:20 – 11:30 AM Pick up box lunch

Session I
Science Relevant to the Understanding
of Ventricular Arrhythmias
Moderator – David Callans, MD
7:30 – 7:45 AM
Anatomy of Substrate for VT
in Structural Heart Disease
Samuel Asirvatham, MD
7:45 – 8:00 AM
Interpretation of
Bipolar/Unipolar Electrograms
John Miller, MD
8:00 – 8:15 AM
ECG of Ventricular Tachycardia
Mark Josephson, MD
8:15 – 8:30 AM
Biophysics of Ablation in Scar
Andre d’Avila, MD, PhD
8:30 – 8:45 AM
Left Cardiac Sympathetic Denervation
in the Presence of VT/VF
Peter Schwartz, MD
8:45 – 9:15 AM
Panel Discussion/Audience Participation
9:15 – 9:45 AM

Break

Session II
Antiarrhythmic Drug Therapy for VT/VF
Moderator – Andrew Epstein, MD
9:45 – 10:00 AM
Acute Pharmacologic Therapy for VT
Jesus Almendral, MD, PhD
10:00 – 10:15 AM
AAD Therapy for Inherited
Arrhythmia Syndromes
Andrew Krahn, MD
10:15 – 10:45 AM
Debate: How Should First Appropriate
ICD Shock be Treated?
Antiarrhythmic Therapy –
Andrew Epstein, MD
Catheter Ablation – Vivek Reddy, MD

11:30 – 1:30 PM

Lunch and Live Cases
Moderator – Francis Marchlinski, MD
EP Lab I
Mathew Hutchinson, MD;
Sanjay Dixit, MD; Michael Riley MD, PhD
EP Lab 2
Fermin Garcia, MD; David Lin, MD;
Gregory Supple, MD
Expert Panel Commentary
Vivek Reddy, MD; William Stevenson, MD;
John Miller, MD; Kalyanam Shivkumar,
MD, PhD; Paolo Della Bella, MD;
Josef Kautzner, MD, PhD
1:30 – 1:45 PM

Break

Session III
How to/What to Look Forward To –
Part 1: Imaging/Noninvasive
ECG Mapping
Moderator – Vivek Reddy, MD
1:45 – 2:00 PM
MR Imaging of the Ventricle in
AF Patients – New Insights
Nassir Marrouche, MD
2:00 – 2:15 PM
MR Imaging in the EP Lab to
Guide VT Ablation
Henry Halperin, MD
2:15 – 2:30 PM
Noninvasive ECG Imaging (ECGi) to
Identify VT Substrate
Yoram Rudy, PhD
2:30 – 2:45 PM
Panel Discussion: Imaging for VT

Session IV
How to/What to Look Forward To –
Part 2: Mapping
Moderator – Vivek Reddy, MD
2:45 – 3:00 PM
VT Substrate Mapping and Electrogram
Analysis in Chagas Disease
Luis C. Sáenz, MD

3:30 – 3:45 PM
Pace Mapping to Localize VT –
“Nancy Technique”
Christian de Chillou, MD, PhD
3:45 – 4:00 PM
Voltage Map Guided Biopsy
Suraj Kapa, MD
4:00 – 4:25 PM
Panel Discussion: Mapping for VT –
What are the Unmet Needs?
David Callans, MD;
Paolo Della Bella, MD
4:25 – 4:45 PM

Break

Session V
How to/What to Look Forward To –
Part 3: Ablation
Moderator – Andre d’Avila, MD, PhD
4:45 – 5:00 PM
Hemodynamic Support Devices:
Patient Selection/Implementation
Gregory Supple, MD
5:00 – 5:15 PM
Important Anticoagulation Issues
Pre, During, and Post VT Ablation
Mathew Hutchinson, MD
5:15 – 5:30 PM
Core Isolation of Critical VT Substrate
Wendy Tzou, MD
5:30 – 5:45 PM
Electroporation in the Ventricle
Fred Wittkampf, PhD
5:45 – 6:00 PM
Bipolar Ablation for Intramural Scar
Srinivas Dukkipati, MD
6:00 – 6:25 PM
Panel Discussion: Ablation for VT –
What are the Unmet Needs?
William Stevenson, MD
David Wilber, MD
Josef Kautzner, MD, PhD
6:30 – 7:30 PM

Reception

7:00 – 7:30 AM
Registration and Continental Breakfast

Session VI
Hypertrophic Cardiomyopathy and VT/VF
Moderator – David Callans, MD
7:30 – 7:45 AM
Imaging for Diagnosis and SCD Risk
Timm Dickfeld, MD, PhD
7:45 – 8:00 AM
Genetic Counseling and
Heart Failure Treatment
Anjali Owens, MD
8:00 – 8:15 AM
Impact of ICD Therapy on Mortality in HCM
Barry Maron, MD
8:15 – 8:30 AM
Catheter Ablation of VT in HCM
Marc Miller, MD
8:30 – 8:50 AM

Discussion

8:50 – 9:15 AM

Break

10:15 – 10:30 AM
NIPs to Program ICDs Post Ablation
Paolo Della Bella, MD
10:30 – 10:50 AM Discussion

Session VIII
Ablation of Focal VT
Moderator – Andre d’Avila, MD, PhD
10:50 – 11:05 AM
ECG and Anatomic Imaging
for LV Summit VT
Pasquale Santangeli, MD
11:05 – 11:20 AM
Ablation of ParaHisian VT
Fermin Garcia, MD
11:20 – 11:35 AM
PVC Triggered VF/LQTS/Brugada
Pierre Jais, MD, PhD
11:35 – 11:50 AM
PVC Ablation in Scarred Myocardium
Frank Bogun, MD
11:50 AM – 12:10 PM

Session VII
Device Therapy
Moderator – Vivek Reddy, MD
9:15 – 9:45 AM
Debate: Do We Implant:
Too many ICDs? – Alfred Buxton, MD
Too few ICDs? – Eric Prystowsky, MD
9:45 – 10:00 AM
ICD Data: What More is Needed
for VT/VF Patient?
Kenneth Ellenbogen, MD
10:00 – 10:15 AM
Combining VT Ablation with Sub-Q ICD:
Important Considerations
David Callans, MD

12:10 – 12:15 PM

Discussion

Pick up box lunch

12:15 – 1:15 PM

2:00 – 2:30 PM
Panel Discussion: What are the Optimal
Targets and Endpoints of VT Ablation?
Vivek Reddy, MD; Frank Bogun, MD;
Andrea Natale, MD; Paolo Della Bella, MD;
David Callans, MD; Pierre Jais, MD, PhD
2:30 – 2:45 PM
Successful Catheter Ablation Improves
Survival – Results From an International
VT Center Collaboration
Roderick Tung, MD
2:45 – 3:00 PM
Mortality Following VT Ablation:
A Glass Half Full?
David Wilber, MD
3:00 – 3:20 PM
Panel Discussion: What Outcome Studies
Will Move the Needle on VT Ablation?
David Wilber, MD; Roderick Tung, MD;
William Sauer, MD; Andre d’Avila, MD, PhD
3:20 – 3:30 PM

Break

Working Lunch
Moderator – David Callans, MD
Summary of Live Cases:
Findings/outcomes from 2014 (20 mins)
Jacob Koruth, MD
Findings/outcomes from 2015 (20 mins)
Mathew Hutchinson, MD

Session IX
Treatment of Ventricular Arrhythmias
Present and Future

Session X
“Bail Outs” for Failed VT
AblationProcedures
Moderator – David Callans, MD
3:30 – 3:45 PM
Stepwise Therapy
William Stevenson, MD

Moderator – Francis Marchlinski, MD

3:45 – 4:00 PM
Neuraxial Ablation
Kalyanam Shivkumar, MD, PhD

1:15 – 1:30 PM
What is the Effect of Early VT Ablation?
Gerhard Hindricks, MD

4:00 – 4:15 PM
Alcohol VT Ablation
Miguel Valderrabano, MD

1:30 – 2:00 PM
Trial Updates: Panel Discussion
STAR VT – Andrea Natale, MD
VANISH – John Sapp, MD
PREVENT VT – Marmar Vaseghi, MD

4:15 – 4:30 PM
Surgical VT Ablation
Sanjay Dixit, MD
4:30 – 4:55 PM
Discussion
4:55 – 5:00 PM
Wrap up and Adjourn
Francis Marchlinski, MD

CME Registration Form
10th International Symposium on

VENTRICULAR ARRHYTHMIAS:
PATHOPHYSIOLOGY & THERAPY

Friday and Saturday
October 9-10, 2015

To register online for the course please visit www.vtsymposium.com
You May Also Mail or Fax Payment and Registration Information to:
VT Symposium Conference Coordinator
Perelman School of Medicine at the University of Pennsylvania
Office of Continuing Medical Education
150 Anatomy/Chemistry Building, 3620 Hamilton Walk, Philadelphia, PA 19104-6061
Phone: 215-898-6400 or 215-898-8005; Fax: 215-898-1888
penncme@mail.med.upenn.edu
Please print or type

Name (First)

(Last)

Academic Degree
Medical Specialty
Affiliation (Hospital, Office, or Company)
■ affiliation ■ home)
Address (■
City

State

Phone

Fax

Zip

E-mail

Registration Fee (pre-payment is required to be officially registered)
Before 9/6/15

On or after 9/6/15

Physicians

■ $525

■ $600

Biomedical, pharmaceutical or medical device
industry employees

■ $525

■ $600

Residents, fellows, and allied health professionals

■ $275

■ $350

Payment Method
Make check payable to the Trustees of the University of Pennsylvania/CME
■ MasterCard
■ Discover
■ American Express

■ Visa

Authorization Signature
Cardholder Name

Security Code

Card #

Exp. Date

For VT Symposium Questions Contact
Phone: 215-662-6005; 215-898-6400 or email: erica.zado@uphs.upenn.edu
or carolyn.siwinski@uphs.upenn.edu (Subject: VT symposium)
Please Note: Walk-in registrants must bring payment to the program.

Hyatt at the Bellevue
200 South Broad Street
Philadelphia, PA 19102

Friday & Saturday
October 9-10, 2015

A C M E - C E RT I F I E D C O U R S E

VENTRICULAR ARRHYTHMIAS:
Pathophysiology & Therapy

10th International Symposium on

150 Anatomy/Chemistry Building
3620 Hamilton Walk
Philadelphia, PA 19104-6061

Non-Profit Org.
U.S. Postage
PA I D
Permit No. 2563
Phila., PA 19104



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