Philips 795200V User Manual Product Whitepaper EPIQ Ultrasound System For Vascular 7 Ff424e23b7774d38ad91a77c014b0374
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Ultrasound EPIQ 7 evolution The of premium vascular ultrasound Philips EPIQ 7 ultrasound system challenges The new in global healthcare Unprecedented advances in premium ultrasound performance can help address the strains on overburdened hospitals and healthcare systems, which are continually being challenged to provide a higher quality of care cost-effectively. The goal is quick and accurate diagnosis the first time and in less time. Premium ultrasound users today demand improved clinical information from each scan, and faster and more consistent exams that are easier to perform and allow for a high level of confidence, even for technically difficult patients. 2 Performance More confidence in your diagnoses even for your most difficult cases EPIQ 7 is the new direction for premium vascular ultrasound, featuring an exceptional level of clinical performance to meet the challenges of today’s most demanding practices. Carotid artery bulb Superficial varicose veins 3 The evolution of premium ultrasound It’s our most powerful architecture ever applied to ultrasound imaging – touching all aspects of acoustic acquisition and processing, allowing you to truly experience ultrasound’s evolution to a more definitive modality. Supported by our family of proprietary xMATRIX and PureWave transducers and our leading-edge Anatomical Intelligence, this platform offers our highest level of premium performance. Key trends in global ultrasound • The need for more definitive premium ultrasound with exceptional image functions to allow for ease of use and quality, performance, and intelligence consistency of exam between users that provides automated views and quantification • A demand for better workflow and greater throughput due to increased ultrasound exam volumes resulting from an aging population 4 • A demand to automate most operator • The need for ultrasound to address the technically challenging patient • A movement to use ultrasound first – even for advanced image-guided therapy – due to concerns about radiation dose and exam cost new realities Creating , redefining clinical expectations nSIGHT Imaging goes beyond conventional ultrasound Penetration Penetrationicons icons performance for new levels of definition and clarity. Conventional Conventional Philips nSIGHT Imaging is a totally new approach Frame rate Uniformity option option44 Penetration The Philips proprietary nSIGHT Imaging architecture introduces a totally new option option55 approach to forming ultrasound images. Unlike conventional systems that form the image line by line, nSIGHT creates images with superb resolution down to the pixel level. Extraordinary architecture nSIGHT Imaging incorporates a custom multi-stage precision beamformer along with massive parallel processing. This proprietary architecture captures an enormous amount of acoustic data from each transmit operation and performs digital beam reconstruction along with mathematically optimized focal processing to create real-time images with exceptional resolution Conventional Users must choose between frame rate and image quality nSIGHT Imaging More than doubles the frame rate without impact to image quality Conventional Best resolution is limited to transmit focal zone nSIGHT Imaging option option66 Corrects focus during beam reconstruction for superb uniformity Conventional Penetration limitations and poor sensitivity to weak signals nSIGHT Imaging Superb penetration across full range of frequencies nSIGHT Imaging nSIGHT Imaging nSIGHT Imaging creates superbly focused achieves superb uniformity architecture’s ultra-wide images with fewer transmit through coherent beam dynamic range and unique operations so you can reconstruction algorithms beam reconstruction experience both highly that apply mathematical reinforces weak tissue detailed ultrasound focal correction coefficients signals allowing enhanced images and extraordinary continually at all depths penetration at higher temporal resolution. of the image. frequencies even on and uniformity. difficult patients. Image quality: the numbers tell the story Comparing EPIQ 7 to conventional premium systems shows breakthrough advances in imaging performance. • Up to 76% increase in penetration (penetration = ability to scan at depths and maintain resolution in order to complete the study* • Up to 213% increase in temporal resolution (ability to maintain resolution at high frame rates)* • Over 85% completion rate for technically challenging exams using nSIGHT Imaging and the PureWave C9-2, as demonstrated in clinical studies** Full range of transducers supports virtually any vascular application. * 2013 quantitative engineering study comparing Philips iU22 ultrasound system with EPIQ 7 ** Summary of results from EMEA technically difficult patient study (EPIQ), 2014 5 Exceptional images for a new era 6 Common carotid artery Posterior tibial veins, technically difficult patient Artery and vein with MicroCPA Common carotid artery plaque Abdominal aorta Carotid bifurcation Greater saphenous vein reflux Common carotid artery Superficial venous thrombosis Venous dialysis access graft Renal vasculature Abnormal Doppler of femoral vein The next generation of Color Flow Imaging Ulnar artery Common femoral artery bifurcation Portal vein/hepatic artery nSIGHT Imaging architecture incorporates new color Doppler technology that increases flow resolution, sensitivity, and frame rate. New proprietary flow algorithms produce exceptional vessel border delineation while preserving 2D imaging characteristics in color Doppler modes. New color map options allow enhanced visualization of flow for color-blind users. New MicroCPA for exceptional small vessel visualization Renal artery Liver capsule vasculature Splenic vasculature In the past, obtaining flow information in small low-flow vascular structures has been a challenge. Now the EPIQ’s MicroCPA feature – visualization of low velocity micro circulation – is quick and simple, allowing for more diagnostic confidence when evaluating organ perfusion or small vascular beds. 7 Maximize extreme clinical capabilities EPIQ 7 offers the ultimate in flexibility to configure any clinical option and application for a true no-compromise cardiovascular imaging system. xMATRIX is our most leading-edge, versatile nSIGHT Imaging makes powerful xMATRIX ultrasound transducer technology technology even more so No other premium ultrasound system can run the complete Achieve ultra-thin 2D slices. Use Live xPlane imaging to suite of the world’s most innovative ultrasound transducers. create two full-resolution planes simultaneously, allowing With the touch of a button xMATRIX offers all modes in a you to capture twice as much clinical information in the single transducer: 2D, 3D/4D, Live xPlane, Live MPR, MPR, same amount of time. Acquire near isovoxel resolution Doppler, color Doppler, and CPA. to reveal images from any plane within the volume. Now it’s all possible. The revolutionary nSIGHT architecture of EPIQ 7 makes xMATRIX even more powerful. See exceptional image quality at all depths and volume rates across all 3D/4D modes and applications with the X6-1 transducer. Leading-edge xMATRIX transducers for cardiology include X5-1 for adult cardiology and X7-2t for TEE applications. 8 Philips pioneered xMATRIX advanced technology Thin slice 2D With xMATRIX, you can achieve ultra-thin, 2D slices. Live xPlane imaging With xMATRIX, you can use Live xPlane imaging to create two full-resolution planes simultaneously, allowing you to capture twice as much clinical information in the same amount of time. 3D/4D Acquire near isovoxel resolution that reveals superb images from any plane within the volume. Send 3D MPRs in the X, Y, and Z plane to any PACS system with MPR DICOM export. Present smooth, real-time 4D volume data. Exclusive panoramic volume imaging with xMATRIX Panoramic volume imaging uses Live xPlane imaging to acquire a calibrated volume over an extended field of view. Easily capture, visualize, and quantify a full organ. Femoral artery Abdominal aorta and iliac arteries xMATRIX panoramic volume imaging allows for whole organ acquisition, visualization, and quantification of anatomical structures and better correlation with other imaging modalities. 9 The power of PureWave to image technically difficult patients PureWave crystal technology represents the biggest breakthrough in piezoelectric transducer material in 40 years. The pure, uniform crystals of PureWave are 85% more efficient than conventional piezoelectric material, resulting in exceptional performance. This technology allows for improved penetration in difficult patients with a single transducer and for excellent detailed resolution. All xMATRIX transducers incorporate PureWave technology. 10 PureWave offers enhanced technology for imaging technically difficult patients in a wide range of applications Liver, technically difficult patient (BMI=55) Apical four-chamber view with mitral regurgitant jet PureWave transducers offer the solution for imaging technically difficult patients in a wide range of applications • PureWave C5-1 and C9-2 for difficult-to-image abdominal and lower extremity applications • PureWave S5-1 for difficult-to-image cardiology patients and transcranial applications PureWave crystals have virtually perfect uniformity for greater bandwidth and twice the efficiency of conventional ceramic materials. The result is excellent imaging and Doppler performance. Conventional (x800) PureWave (x800) 11 Elastography for more definitive information about tissue stiffness The EPIQ platform supports both strain and shear wave methods of elastography. Highly sensitive strain imaging can be used to rapidly assess relative tissue stiffness values across a variety of applications. Shear wave elastography utilizes a unique pulsing scheme to generate and detect the propagation speed of shear waves, providing an absolute measure of tissue stiffness. In addition, the EPIQ platform is designed to support the future of elastography including quantitative real-time shear wave imaging across a variety of transducers and applications. Shear wave elastography ElastPQ uses ultrasound shear wave elastography to provide a non-invasive, reproducible, and easily performed method of assessing tissue stiffness. A special pulse sequence technique using existing transducers produces shear waves in tissue and measures the propagation speed of the waves. Now tissue stiffness samples can be acquired during a routine ultrasound examination of the liver. According to Elasto point quantification the latest studies,1 using shear wave elastography may help reduce or avoid conventional liver biopsies. Many studies are suggesting that instead of a costly and painful biopsy procedure, an easy ultrasound exam becomes the routine method to assess liver disease status. 1 Ferraioli G, et al. Point shear wave elastography method for assessing liver stiffness. World J Gastroenterol 2014 April 28;20(16):4787-4796. 12 Revolutionize your contrast exam EPIQ 7 provides instant optimization of contrast-enhanced ultrasound (CEUS)* studies and exceptional performance across multiple agents and applications. nSIGHT Imaging allows higher sensitivity to lower bubble concentrations while providing exceptional temporal resolution during critical wash-in/wash-out phases. Among leading ultrasound manufacturers, Philips offers the world’s only live 3D images using contrast for general imaging with real-time 3D contrast data for dynamic clinical assessment. Carotid bulb Kidney Aortic Type II endoleak Liver abscess * In the U.S. contrast is only approved for cardiac use. 13 Fast and effective image fusion and needle navigation Make confident decisions even in challenging diagnostic By combining imaging modalities directly on the ultrasound cases with fully integrated fusion capabilities that feature system, you now have access to an even more powerful streamlined workflows to allow clinicians to achieve fast diagnostic tool with advanced visualization allowing for fast and effective fusion of CT/MR/PET with live ultrasound. clinical decisions. 14 Fusion and navigation Expand vascular fusion and navigation capabilities through a range of PureWave transducers including the X6-1 xMATRIX, Cerebral artery assessment using transcranial ultrasound and CT fusion Post EVAR assessment using ultrasound and CT fusion Fast and effective image fusion Advanced needle navigation Make confident decisions even in Needle navigation is a performance- challenging diagnostic cases with enhancing tool for challenging fully integrated fusion capabilities interventional cases such as a that feature streamlined workflows hard-to-visualize small-lesion biopsy to allow clinicians to achieve fast or difficult-to-access ablations that are and effective fusion of CT/MR/PET close to critical structures. Procedures with live ultrasound. may now be completed in less time S5-1 (abdominal and transcranial), C5-1, and C9-2. By combining imaging modalities and with fewer confirmatory scans.2 directly on the ultrasound system, A reusable adaptive needle tracker and you now have access to an even more an expanded range of coaxial needle-tip powerful diagnostic tool with advanced tracked instruments offer you a wide visualization, allowing for fast decisions range of compatibility with biopsy and compared to without fusion. ablation devices depending on the degree of procedure complexity. 2 Kim E, et al. CT-Guided liver biopsy with electromagnetic tracking: results from a single-center prospective randomized controlled trial. American Journal Roentgenology 2014;203:W715-723. 15 Designed to reinvent the user experience EPIQ 7 has completely reinvented the premium ultrasound user experience. Ease of use, workflow, ergonomics, portability – we’ve revolutionized how you interact with an ultrasound system from every standpoint, and kept it beautifully intuitive. More than 80% of sonographers experience work-related pain, and more than 20% of these suffer a career-ending injury.3 The EPIQ tablet-like interface results in dramatic reduction in reach and button pushes, with 40% to 80% less reach and 15% fewer steps.* Advanced workflow Amazingly portable The design of the platform features At just 104 kg (230 lb), EPIQ 7 is lightest “walk-up usability,” meaning that in its class and 40% lighter than the users can perform an exam with heaviest competitive premium system. minimal training.4 The system offers Easily transport EPIQ 7 on both carpet the automation to drive efficiency and tile floors. Place it in sleep mode, throughout exams with features such move it, and boot up in seconds. as Real Time iSCAN (AutoSCAN), The monitor folds down to reduce which automatically enhances gain overall system height for transport, and TGC continuously to provide and the integrated cable hooks and excellent images in 2D, 3D, or 4D. catch tray are ideal for portable Tablet-like touch interface allows studies. Wireless DICOM further quick navigation to system functions aids workflow.† with 40% to 80% less reach and 15% fewer steps to complete an exam. 16 in complete studies, less focus on requirements, less repetitive motion, less stress, and improved schedule maintenance and department efficiencies. Auto Doppler for vascular imaging Auto Doppler takes time-consuming color box positioning and sample volume placement from ten steps Library quiet to three steps and reduces the number EPIQ 7 is almost silent when running. of repetitive button pushes by an A noise test determined that EPIQ 7 average of 68%.6 runs at 37-41 dB, which is equivalent to the sound of a library. Active native data Active native data allows for post- Scanning comfort processing of many exam parameters. Multiple degrees of articulation for both the control panel and 54.6 cm Set-up Wizard (21.5 in) LCD monitor with 720° Set-up Wizard allows users to step of freedom allows for ergonomic up to the system, easily establish user alignment, whether sitting or standing, configurations, and get running quickly. Easy viewing and efficient use even in darker scanning environments with a large 54.6 cm (21.5 in) wide screen and ambient lighting that provides subtle visual cues for the keyboard, OEMS, and transducer ports. for scanning comfort. Access to multimodality images SmartExam Use multimodality query retrieve to SmartExam decreases exam time view DICOM images such as CT, NM, by 30-50%, keystrokes by as many MR, mammography, and ultrasound. as 300 per exam, and results in Easily compare past and current a high level of consistency among studies without the use of an external users.5 It is fast and easy to customize, reading station and even review these providing consistent annotation, multimodality images while live imaging. automatic mode switching, and missed view alerts to streamline exams. The result is more time to focus on your patients, increased confidence EPIQ 7 makes it easy to be green 25% less power EPIQ 7 is one of the greenest systems we have ever designed. It consumes 25% less power than our legacy premium ultrasound. Society of Diagnostic Medical Sonography, Industry Standards for the Prevention of Musculoskeletal Disorders in Sonography, May 2003. External user study where all users had over 90% success (gold standard in usability) on their set tasks with no training on EPIQ, Jan 2013. 5 University of Colorado, Protocols Study, Apr. 2007. 6 Auto Doppler Clinical Study, Dec. 2011. * 2013 engineering study comparing Philips iU22 ultrasound system with EPIQ 7. † Check for availability in your geography. 3 4 17 Intelligence turning images into answers a2DQ A.I. with ZeroClick for fast, reproducible EF on all your patients. 18 aCMQA.I. with ZeroClick technology provides both EF and GLS from the same 2D images. Anatomical Intelligence is the heart of EPIQ 7 At the heart of the powerful EPIQ 7 architecture is our Philips exclusive Anatomical Intelligence Ultrasound (AIUS), designed to elevate the ultrasound system from a passive to an actively adaptive device. With advanced organ modeling, image slicing, and proven quantification, exams are easy to perform, more reproducible, and deliver new levels of clinical information. AIUS ranges from automating repetitive steps to full-blown computerdriven analysis with minimal user interaction – all using anatomic intelligence and all providing the results you need. In fact, many of our tools come with ZeroClick technology, which means that once loaded, the tool does it all for you.* Q-App quantification applications EPIQ 7 offers a wide variety of sophisticated Q-Apps to quantify ultrasound image information. Vascular Q-Apps Cardiology Q-Apps • Intima Media Thickness (IMT) • Strain Quantification (SQ) • General Imaging 3D Quantification (GI 3DQ) • Cardiac 3D Quantification (3DQ) • Region of Interest (ROI) • Cardiac 3D Advanced Quantification (3DQ Advanced) • MicroVascular Imaging (MVI) • CMQ Stress • Vascular Plaque Quantification (VPQ) • Mitral Valve NavigationA.I. (MVNA.I.) • Automated 2D Cardiac QuantificationA.I. (a2DQA.I.) • Automated Cardiac Motion QuantificationA.I. (aCMQA.I.) *Edit option 19 Anatomical Intelligence Achieve new levels of simplicity Automation Automated 2D Cardiac QuantificationA.I. (a2DQA.I.) Automated Cardiac Motion QuantificationA.I. with ZeroClick technology for adult and pediatric echo (aCMQ A.I.) with ZeroClick technology for adult echo The ideal tool of every echo lab, Automated 2D Cardiac The ZeroClick technology of the Automated Cardiac Motion QuantificationA.I. (a2DQA.I.) with ZeroClick technology uses QuantificationA.I. (aCMQA.I.) uses speckle mechanics to AIUS for an Auto-ROI to drive the Q-App and provide rapid provide reproducible 2D Global Longitudinal Strain (GLS) access to proven 2D EF and volumes. AutoEF is available speckle measurements. A proven EF is also calculated by during the study and so fits in with an everyday echo protocol. using the Auto-ROI that drives the automation within the aCMQA.I. Q-App. 20 Automatic registration for image fusion and navigation CT and ultrasound vessel and surface registration allow you to complete the challenging task of registering a CT volume with ultrasound in less Anatomical Intelligence liver vessel segmentation for CT and ultrasound provides image fusion in less than one minute. than one minute – 1/10 the standard alignment time. Navigation The Mitral Valve Navigator A.I. (MVNA.I.) The Mitral Valve NavigatorA.I. (MVNA.I.) is designed to take a Live 3D volume of the mitral valve and turn it into an easyto-interpret model in eight guided steps, providing access to a comprehensive list of MV measurements and calculations. Internal comparison of MVQ to MVNA.I. tools measures 89% fewer clicks.3 MVNA.I. saves steps at each part of the process Annulus data is acquired with 74% fewer clicks,3 which also provides leaflet tracing with no user interaction. MVNA.I. MVNA.I. takes a Live 3D volume of the mitral valve and turns it into an easy-to-interpret model in just eight guided steps. guides the entire process using simple commands and clear graphics, making this a much easier tool to use than previous mitral quantification tools. Results derived from MVNA.I. can be seen on the screen as they become available, speeding the process of accessing required data. Vascular Plaque Quantification (VPQ) Vascular Plaque Quantification is a non-invasive tool that uses 3D technology to visualize and quantify both the overall volume of vascular plaque in the carotid artery and the percent area of vessel reduction, as well as other characteristics of plaque composition. VPQ may prove to be a valuable tool to aid in determining who is at an increased risk of stroke or cardiovascular disease based on this important measurement of plaque buildup in the VPQ and the VL13-5 transducer allow advanced analysis of plaque volume and morphology. carotid artery. 3. 2013 QLAB 9 MVQ and QLAB 10 MVN click comparison internal study. 21 Advanced support services are proactive and predictive We understand your challenges: uncertain economic times, changing healthcare landscapes, and the impact of healthcare reform. We know that efficient workflows and system uptime are critical success factors in running an effective healthcare business. Philips is committed to offering innovative solutions to provide you with world-class services that move from reactive to proactive and with predictive service models that provide high system availability and enhanced workflow to help you deliver high quality patient care. Remote services mean we’re closer than ever* Remote desktop Spend less time on the phone with a Philips “Virtual Visit” with remote system interaction for fast technical and clinical troubleshooting and guided scanning options. iSSL technology This industry-standard protocol meets global privacy standards and provides a safe and secure connection to the Philips remote services network using your existing Internet access point. Online support request Enter a support request directly from your EPIQ system for a fast, convenient communication mechanism that reduces workflow interruption and keeps you at the system and focused on your patient. Utilization reports Data intelligence tools that can help you make informed decisions to improve workflow, deliver quality patient care, and decrease the total cost of ownership. This ultrasound utilization tool provides individual transducer usage and the ability to sort by exam type. Proactive monitoring Proactive monitoring allows for the detection and repair of anomalies before they become problems and helps us to better predict potential failures and proactively act on them. Increase system availability, optimize workflow, and promote patient satisfaction by scheduling downtime as opposed to reacting to an unexpected problem. 22 *Check for availability in your geography. The remote desktop allows Philips service engineers to gain a live view of your system’s console for remote operation, real-time clinical troubleshooting, and issue resolution. Exceptional serviceability Philips offers the only ultrasound utilization tool that provides individual transducer usage and the ability to sort by exam type. The system features superior modular design for rapid repair, getting your system up and running quickly. Intelligent software architecture Software is easily optimized, maintained, and restored by the service user without risk to patient data, giving you peace of mind when dealing with software anomalies and confidence that your data is safe. This software architecture takes patient data privacy to a new level. Patient data is stored on a separate partition and physical location to provide protection and ease of removal, providing you total control of your data. Clinical education solutions Our comprehensive, clinically relevant courses, programs, and learning paths are designed to help you improve operational efficiency and enhance patient care. 23 © 2016 Koninklijke Philips N.V. All rights are reserved. Philips reserves the right to make changes in specifications and/or to discontinue any product at any time without notice or obligation and will not be liable for any consequences resulting from the use of this publication. Trademarks are the property of Koninklijke Philips N.V. or their respective owners Please visit www.philips.com/epiq Printed in The Netherlands. 4522 991 17771 * FEB 2016
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xmp.iid:9ED996E7A72068118C14DF41AD074C43, xmp.iid:CFAAB33DA82068118C14DF41AD074C43, xmp.iid:D1AAB33DA82068118C14DF41AD074C43, xmp.iid:4BB7A962A92068118C14DF41AD074C43, xmp.iid:4CB7A962A92068118C14DF41AD074C43, xmp.iid:C978DC280E206811822ACC30980EB629, xmp.iid:9C9A1D7C0E206811822ACC30980EB629, xmp.iid:D42DF2130F206811822ACC30980EB629, xmp.iid:31AB058A10206811822ACC30980EB629, xmp.iid:F98ACA0115206811822ACC30980EB629, xmp.iid:7350715316206811822ACC30980EB629, xmp.iid:7650715316206811822ACC30980EB629, xmp.iid:7750715316206811822ACC30980EB629, xmp.iid:D3A16AC045206811822ACC30980EB629, xmp.iid:F31B2BAA49206811822ACC30980EB629, xmp.iid:4D697C6A5C206811822ACC30980EB629, xmp.iid:DEA2D9D65C206811822ACC30980EB629, xmp.iid:BF70A1A668206811822ACC30980EB629, xmp.iid:222E507A302068118083DA97FB71045B, xmp.iid:94305E9D312068118083DA97FB71045B, xmp.iid:95305E9D312068118083DA97FB71045B, xmp.iid:FCF8F98007206811808399E0D0D16B12, xmp.iid:3B990FAE0A206811808397FBA8774BB0, xmp.iid:837C81010B206811808397FBA8774BB0, xmp.iid:3CA515B20B206811808397FBA8774BB0, xmp.iid:F7497A190C206811808397FBA8774BB0, xmp.iid:9210E4470C206811808397FBA8774BB0, xmp.iid:46D2D84B0C206811808397FBA8774BB0, xmp.iid:4B98E35B0C206811808397FBA8774BB0, xmp.iid:3243027F0C206811808397FBA8774BB0, xmp.iid:E8CD429E0C206811808397FBA8774BB0, xmp.iid:C1E84DE40C206811808397FBA8774BB0, xmp.iid:283335130D206811808397FBA8774BB0, xmp.iid:2A3335130D206811808397FBA8774BB0, xmp.iid:5C967B640D206811808397FBA8774BB0, xmp.iid:5D967B640D206811808397FBA8774BB0, xmp.iid:5E967B640D206811808397FBA8774BB0, xmp.iid:5F967B640D206811808397FBA8774BB0, xmp.iid:60967B640D206811808397FBA8774BB0, xmp.iid:27F1FA110E206811808397FBA8774BB0, xmp.iid:0EC2D27973206811808397FBA8774BB0, xmp.iid:EF13B10274206811808397FBA8774BB0, xmp.iid:F013B10274206811808397FBA8774BB0, xmp.iid:0BE8DC7774206811808397FBA8774BB0, xmp.iid:0CE8DC7774206811808397FBA8774BB0, xmp.iid:3AF44FE2072068118083A3A944D5256D, xmp.iid:3BF44FE2072068118083A3A944D5256D, xmp.iid:135F6DF00A2068118083A3A944D5256D, xmp.iid:145F6DF00A2068118083A3A944D5256D, xmp.iid:D798AFFB0A2068118083A3A944D5256D, xmp.iid:FBCD27530B2068118083A3A944D5256D, xmp.iid:94E9AEA20B2068118083A3A944D5256D, xmp.iid:95E9AEA20B2068118083A3A944D5256D, xmp.iid:F7A6A5CF152068118083A3A944D5256D, xmp.iid:961831C3162068118083A3A944D5256D History When : 2012:10:29 11:26:30+01:00, 2012:10:29 11:26:30+01:00, 2012:10:29 11:33:22+01:00, 2012:10:29 11:33:22+01:00, 2012:11:05 11:07:34+01:00, 2012:11:05 11:07:34+01:00, 2013:05:14 16:53:01+02:00, 2013:05:14 16:53:01+02:00, 2013:05:14 16:56:15+02:00, 2013:05:17 07:38:49+02:00, 2013:05:17 07:38:49+02:00, 2014:05:14 10:12:15+02:00, 2014:05:14 10:12:15+02:00, 2014:05:14 10:26:07+02:00, 2014:06:10 15:36:51+02:00, 2014:06:10 15:37:18+02:00, 2014:06:10 15:37:18+02:00, 2014:07:10 12:16:42+02:00, 2014:07:10 12:16:42+02:00, 2014:07:10 12:18:31+02:00, 2014:07:10 12:31:54+02:00, 2014:07:10 12:40:38+02:00, 2014:07:10 12:40:38+02:00, 2014:07:16 12:41:14+02:00, 2014:07:16 12:41:14+02:00, 2014:07:16 12:52:38+02:00, 2014:07:16 13:44:49+02:00, 2014:07:16 13:46:57+02:00, 2014:07:16 13:46:57+02:00, 2014:09:08 14:23:19-04:00, 2014:09:08 14:23:19-04:00, 2014:09:08 14:40:24-04:00, 2014:09:08 14:42:34-04:00, 2014:09:09 15:13:50-04:00, 2014:09:09 15:30:21-04:00, 2014:09:09 17:40:56-04:00, 2014:09:12 16:37:57-04:00, 2014:09:12 17:13:22-04:00, 2014:09:12 17:26:26-04:00, 2014:09:12 17:26:26-04:00, 2014:09:12 17:33:36-04:00, 2014:09:16 11:40:58-04:00, 2014:09:16 11:40:58-04:00, 2014:09:16 11:45:51-04:00, 2014:09:16 12:04:30-04:00, 2014:09:16 12:15:32-04:00, 2014:09:16 12:19:08-04:00, 2014:09:16 12:19:57-04:00, 2014:09:16 12:26:36-04:00, 2014:09:16 12:46:25-04:00, 2014:09:16 12:50:09-04:00, 2014:09:16 13:48:57-04:00, 2014:09:16 13:52:04-04:00, 2014:09:16 22:45:06-04:00, 2014:09:16 22:57:41-04:00, 2014:09:16 23:06:15-04:00, 2014:09:16 23:10:03-04:00, 2014:09:17 13:39:36-04:00, 2014:09:17 14:00:09-04:00, 2014:09:17 14:49:29-04:00, 2014:09:17 14:57-04:00, 2014:09:18 10:29:13-04:00, 2014:09:18 10:30:16-04:00, 2014:09:21 11:20:07-04:00, 2014:09:21 11:20:07-04:00, 2014:10:23 11:57:48-04:00, 2014:10:28 12:43:53-04:00, 2014:10:28 12:44:29-04:00, 2014:10:28 12:44:29-04:00, 2014:11:10 21:38:52-05:00, 2014:11:10 21:38:52-05:00, 2014:11:12 14:12:24-05:00, 2014:11:17 13:07:17-05:00, 2014:11:17 13:11:12-05:00, 2014:11:17 13:11:12-05:00, 2014:11:18 11:49:26-05:00, 2014:11:18 11:49:26-05:00, 2014:11:18 11:58:49-05:00, 2015:01:03 15:57:48-05:00, 2015:01:03 15:59:57-05:00, 2015:01:03 15:59:57-05:00, 2015:01:03 16:33:16-05:00, 2015:01:03 17:35:30-05:00, 2015:01:03 17:35:30-05:00, 2015:01:03 17:36:22-05:00, 2015:01:03 17:36:22-05:00, 2015:01:09 15:47:12-05:00, 2015:01:09 18:38:21-05:00, 2015:01:09 18:38:21-05:00, 2015:02:05 16:01:15-05:00, 2015:02:09 15:53:09-05:00, 2015:02:09 15:53:09-05:00, 2015:02:17 17:20:22-05:00, 2015:02:18 15:36:46-05:00, 2015:02:18 15:36:47-05:00, 2015:02:27 15:06:16-05:00, 2015:02:27 16:04:15-05:00, 2015:02:27 16:04:16-05:00, 2015:03:05 16:34:55-05:00, 2015:03:10 16:03:58-04:00, 2015:03:10 16:03:59-04:00, 2015:03:13 11:57:58-04:00, 2015:03:13 11:58:09-04:00, 2015:03:13 11:58:09-04:00, 2015:03:30 12:27:17-04:00, 2015:03:30 12:27:27-04:00, 2015:03:30 12:27:27-04:00, 2015:03:31 13:24:43-04:00, 2015:03:31 13:24:43-04:00, 2015:03:31 18:55:28-04:00, 2015:03:31 19:03:50-04:00, 2015:03:31 19:03:50-04:00, 2015:03:31 16:58:03-07:00, 2015:03:31 16:58:03-07:00, 2015:04:01 10:06:18-07:00, 2015:04:01 10:07:16-07:00, 2015:04:01 10:07:28-07:00, 2015:04:01 10:08:49-07:00, 2015:04:01 10:17:55-07:00, 2015:04:01 10:18:23-07:00, 2015:04:01 10:19:16-07:00, 2015:04:01 10:20:55-07:00, 2015:04:01 10:23:31-07:00, 2015:04:01 10:24:34-07:00, 2015:04:01 10:34:06-07:00, 2015:04:01 10:54:46-07:00, 2015:04:01 11:02:18-07:00, 2015:04:01 11:27:09-07:00, 2015:04:01 12:03:19-07:00, 2015:04:01 12:30:49-07:00, 2015:04:01 13:07:30-07:00, 2015:04:01 13:57:41-07:00, 2015:04:01 13:57:46-07:00, 2015:04:02 16:25:39-07:00, 2015:04:02 17:05:30-07:00, 2015:04:02 17:06:09-07:00, 2015:04:02 17:10:19-07:00, 2015:04:02 17:10:59-07:00, 2015:04:02 17:17:56-07:00, 2015:04:02 17:18:53-07:00, 2015:04:02 17:20:08-07:00, 2015:04:02 17:20:35-07:00, 2015:04:02 17:21:04-07:00, 2015:04:02 17:22:26-07:00, 2015:04:02 17:22:39-07:00, 2015:04:02 17:42:58-07:00, 2015:04:02 17:44:47-07:00, 2015:04:02 17:57:08-07:00, 2015:04:02 18:23:40-07:00, 2015:04:02 18:29:13-07:00, 2015:04:02 18:29:13-07:00, 2015:04:02 18:32:29-07:00, 2015:04:02 18:33:17-07:00, 2015:04:02 18:56:39-07:00, 2015:04:02 19:00:45-07:00, 2015:04:02 19:02-07:00, 2015:04:09 12:47:36-07:00, 2015:04:09 12:47:42-07:00, 2015:04:09 12:47:42-07:00, 2015:04:09 12:48:35-07:00, 2015:04:09 12:56:23-07:00, 2015:04:09 13:08:58-07:00, 2015:04:09 13:34:28-07:00, 2015:04:09 15:58:13-07:00, 2015:04:09 15:58:54-07:00, 2015:04:09 16:01:12-07:00, 2015:04:09 16:02:51-07:00, 2015:04:09 16:07:06-07:00, 2015:04:09 16:09:56-07:00, 2015:04:09 18:31:59-07:00, 2015:04:13 17:59:08-07:00, 2015:04:13 18:01:13-07:00, 2015:04:13 18:01:27-07:00, 2015:04:13 18:02:02-07:00, 2015:04:13 18:02:18-07:00, 2015:04:13 18:02:29-07:00, 2015:04:13 18:02:45-07:00, 2015:04:13 18:02:56-07:00, 2015:04:13 18:03:10-07:00, 2015:04:13 18:32:26-07:00, 2015:04:13 18:32:38-07:00, 2015:04:13 18:32:47-07:00, 2015:04:13 18:34:24-07:00, 2015:04:13 18:37:38-07:00, 2015:04:14 10:49:35-07:00, 2015:04:14 11:00:03-07:00, 2015:04:14 11:06:23-07:00, 2015:04:14 11:08:07-07:00, 2015:04:14 11:09:49-07:00, 2015:04:14 11:12:54-07:00, 2015:04:14 11:18:02-07:00, 2015:04:14 11:22:51-07:00, 2015:04:14 16:33:47-07:00, 2015:04:14 16:33:54-07:00, 2015:04:15 09:41:05-07:00, 2015:04:15 09:45:14-07:00, 2015:04:15 09:52:21-07:00, 2015:04:15 09:52:47-07:00, 2015:04:15 09:54:47-07:00, 2015:04:15 09:55:50-07:00, 2015:04:15 09:56:14-07:00, 2015:04:15 09:56:14-07:00, 2015:04:15 09:58:32-07:00, 2015:04:15 10:00:12-07:00, 2015:04:15 10:00:51-07:00, 2015:04:15 10:01:14-07:00, 2015:04:15 10:02:18-07:00, 2015:04:15 10:03:15-07:00, 2015:04:15 10:04:51-07:00, 2015:04:15 10:05:17-07:00, 2015:04:15 10:05:17-07:00, 2015:04:15 10:08:07-07:00, 2015:04:15 10:39:48-07:00, 2015:04:15 11:04:50-07:00, 2015:04:15 15:33:27-07:00, 2015:04:16 10:59:25-07:00, 2015:04:16 11:18:06-07:00, 2015:04:16 11:26:04-07:00, 2015:04:16 11:28:06-07:00, 2015:04:16 15:35:27-07:00, 2015:04:16 15:44:43-07:00, 2015:04:16 15:47:38-07:00, 2015:04:16 15:48:15-07:00, 2015:04:16 15:51:47-07:00, 2015:04:16 16:01:49-07:00, 2015:04:16 16:03:54-07:00, 2015:04:16 16:22:03-07:00, 2015:04:16 16:28:43-07:00, 2015:04:16 16:28:43-07:00, 2015:04:17 10:19:12-07:00, 2015:04:18 11:31:22-07:00, 2015:04:18 11:31:36-07:00, 2015:04:18 11:45:07-07:00, 2015:04:18 11:46:23-07:00, 2015:04:18 11:46:50-07:00, 2015:04:18 11:58:50-07:00, 2015:04:18 12:00:04-07:00, 2015:04:18 12:00:44-07:00, 2015:04:18 12:01:30-07:00, 2015:04:18 12:02:24-07:00, 2015:04:18 12:03:07-07:00, 2015:04:18 12:04:01-07:00, 2015:04:20 10:40:22-07:00, 2015:04:20 10:43-07:00, 2015:04:20 10:43-07:00, 2015:04:20 12:57:40-07:00, 2015:04:20 13:28:29-07:00, 2015:04:20 13:31:34-07:00, 2015:04:20 13:33:54-07:00, 2015:04:20 13:41:31-07:00, 2015:04:20 13:43:20-07:00, 2015:04:20 13:43:47-07:00, 2015:04:20 14:04:59-07:00, 2015:04:20 14:36:57-07:00, 2015:04:20 14:38:31-07:00, 2015:04:20 14:38:50-07:00, 2015:04:20 14:41:16-07:00, 2015:04:20 14:45:21-07:00, 2015:04:20 14:52:38-07:00, 2015:04:20 14:53:58-07:00, 2015:04:20 15:04:40-07:00, 2015:04:20 15:05:16-07:00, 2015:04:21 12:47:27-07:00, 2015:04:21 12:48-07:00, 2015:04:21 12:48-07:00, 2015:04:21 12:55:21-07:00, 2015:04:21 13:36:34-07:00, 2015:04:22 13:29:09-07:00, 2015:04:22 13:29:09-07:00, 2015:04:22 13:38:17-07:00, 2015:04:22 13:48:08-07:00, 2015:04:22 13:49:01-07:00, 2015:04:22 13:50:34-07:00, 2015:04:22 13:52:10-07:00, 2015:04:22 14:01:31-07:00, 2015:04:22 14:05:10-07:00, 2015:04:22 14:07:16-07:00, 2015:04:22 14:08:05-07:00, 2015:04:22 14:08:58-07:00, 2015:04:22 14:09:42-07:00, 2015:04:22 14:09:42-07:00, 2015:04:22 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