Curriculum Vitae: Raymond Kwong
FDA/CDER
Kwong-Raymond-Unredacted-CV-20190525 Work Phone: Work Email:
Harvard Medical School 857-307-1960
rykwong@bwh.harvard.edu
Education 1988 B.Sc.
Biochemistry (2 years of a 3-year program completed due to acceptance to Medical School)
Curriculum Vitae
Date Prepared: May 25th, 2019
Name:
Raymond Y. Kwong
Office Address: 75 Francis Street, Boston, Massachusetts, USA 02115
1992 M.D. Medicine 2006 M.P.H. Clinical Effectiveness
University of Toronto, Toronto, Ontario, Canada University of Toronto Harvard School of Public Health (HSPH), Boston, MA
Postdoctoral Training
07/92- Rotating 06/93 Intern
Medicine/Surgery
Saint Joseph Health Center, University of Toronto, Toronto, Ontario
Resident 07/9306/97
Fellow 07/9706/00
Internal Medicine
Cardiovascular Cardiovascular Medicine
Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia
Diseases, George Washington University Medical Center, Washington, DC
07/99- Research 08/01 Fellow
Cardiovascular Magnetic Resonance Imaging
Faculty Academic Appointments
National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD
1
07/01-12/07
01/08-04/13 05/13-present
Instructor
Assistant Professor Associate Professor
Medicine
Medicine Medicine
Harvard Medical School (HMS), Boston, MA HMS HMS
Appointments at Hospitals/Affiliated Institutions
09/01-04/13
Associate Physician
Cardiovascular Medicine
05/13-present 09/01-present
Physician Associate Radiologist
Cardiovascular Medicine Radiology
Brigham and Women's Hospital (BWH), Boston, MA BWH
BWH
Other Professional Positions
2011 2011-present
2013-2017 2017 2017-2021
Scientific Advisory Board
Lantheus Medical Imaging, Inc., N. Billerica, MA
Magnetic Resonance Imaging St. Jude Medical, St. Paul, MN
Steering Committee
(2 days per year)
Special Government Employee United States Food and Drug Administration
(FDA)
Scientific Advisory Board
Heart Failure Scientific Advisory Board Meeting,
Amgen Inc., Washington DC
Special Government Employee United States Food and Drug Administration
(1 day per year)
(FDA) Medical Imaging Drugs Advisory
Committee
Major Administrative Leadership Positions
Local 2001-2007
2007-present
Co-Director, Cardiac Magnetic Resonance BWH Imaging/Computed
Tomography
Director, Cardiac Magnetic Resonance Imaging
BWH
Committee Service
Local 2002-2004 2004-present
2006-present 2007-present
Member, Emerging Clinical Leaders Joint Cardiology/Radiology Advanced Cardiovascular Imaging Committee Clinical Magnetic Resonance Service Committee Member, Non-invasive Cardiovascular Imaging
BWH BWH
BWH BWH
2
National 2009-2014
Section
Data Safety Monitoring Board (DSMB),
NIH
Protocol: Vascular impairment in type II diabetes
mellitus with co-morbid obstructive sleep apnea, NIH
(NHLBI) Protocol Number: R01 HL110350, PI:
Atul Malhotra, M.D.
Professional Societies 1999-present Society for Cardiovascular Magnetic Resonance (SCMR)
2003-present Abstract Grader for the SCMR Annual Scientific Meetings 2006-2007 Member, SCMR Finance Committee 2008/2009 Representative for SCMR 2009 appropriate use criteria for cardiac
radionuclide imaging: a report of the American College of Cardiology (ACC) Foundation Appropriate Use Criteria Task Force 2008-2010 Member, SCMR Annual Scientific Meeting Program Planning Committee 2010-2011 Co-Chair, SCMR Annual Scientific Meeting Program Planning Committee 2010-2013 Member, Board of Trustees and Executive Committee 2011-2012 Chair, SCMR Annual Scientific Meeting Program Planning Committee 2011-present Member, SCMR United States Advisory Committee 2011-present Mentor, SCMR Mentorship Program for Fellows 2012-2016 Member, SCMR Gold Medalist Award Committee 2013-2016 Co-Chair, SCMR International Outreach Committee 2013-2018 Chair, SCMR Global Registry Committee 2019-2022 Member, SCMR Global Registry Committee 2019-2022 Chair, SCMR Clinical Trial Committee
1999-present
American Heart Association (AHA) 2004-present Abstract Grader for the AHA Annual Scientific Meetings
2017-2019 Member, Cardiovascular Imaging Council
2019-2020
Co-Chair, AHA Writing Group: State of the Art: Imaging for Myocardial Viability
2000-2004 2004-present
International Society of Magnetic Resonance in Medicine (ISMRM)
American College of Cardiology (ACC)
2004-present 2006-2007
Abstract Grader for the ACC Annual Scientific Meetings Member, Integrated Imaging Spotlight Program Planning Committee
3
2005-2008 2017-2019
2012-present ACC Foundation (ACCF)/AHA Task Force on Clinical Data Standards, Writing Group for Standards Related to Ischemia and Risk
2018-2019 Writing Group Member as the representative appointed by SCMR, 2018 Appropriate Use Criteria for Stable Ischemic Heart Disease: a report of the American College of Cardiology (ACC) Foundation Appropriate Use Criteria Task Force
Society of Cardiac Computed Tomography (SCCT), Member American Society of Nuclear Cardiology (ASNC) Writing group member, Multimodality Imaging of Cardiac Amyloidosis, as the representative appointed by SCMR
Grant Review Activities
2010; 2012 2010; 2013 2011
2011 2012
2012 2013; 2014 2014 2014-2020
Clinical Innovation Grant Selection
BWH
Committee, Department of Medicine
Ad hoc member
Grant Review
Medical Research Council (MRC),
United Kingdom
Ad hoc reviewer
R41/42/43/44 Study Section, Special
NIH
Emphasis Panel/Scientific Review Group Ad hoc member
2012/01 (Meeting Code: ZRG1 CVRS-B
10), Small Business: Cardiovascular
Sciences
RO1 Study Section, Epidemiology NIH
2012/01 (Meeting Code: ZRG1 PSE-K 03) Ad hoc member
RO1 Study Section, Request for
NIH
Application "Pulmonary Vascular-Right Ad hoc member
Ventricular Axis Research Program"
(Meeting Code: RFA HL-12-021)
Advanced Imaging Pilot Research Grants Harvard Catalyst
and Concept Development Awards Ad hoc member Program
Grant-in-Aid
Heart and Stroke Foundation of
Canada
Ad hoc member
Special Emphasis Panel Study Section NIH
(Cardiovascular and Respiratory Sciences Ad hoc member
ZRG1 CVRS-B 02)
Clinical Integrated Cardiovascular Science NIH
(CICS) Study Section
Permanent member
2016
Vice-Chair, Oct 2016 Study Section
4
Editorial Activities
Ad Hoc Reviewer American Journal of Cardiology (AJC) Circulation Circulation Cardiovascular Imaging Circulation, Electrophysiology Circulation Research European Heart Journal (EHJ) European Journal of Clinical Investigation International Journal of Cardiovascular Imaging Journal of Cardiovascular Magnetic Resonance (JCMR) Journal of the American College of Cardiology (JACC) JACC Cardiovascular Imaging Journal of the American Heart Association (JAHA) Journal of American Medical Association (JAMA) Cardiology The Lancet Magnetic Resonance in Medicine (MRM) New England Journal of Medicine (NEJM)
Other Editorial Roles
2004-2008 Editorial Board Member
Circulation
2006-2015 Co-Editor, Images in Cardiovascular Medicine Circulation
(Special Section)
2018-2019 Guest Editor
Circulation
2007-present Editorial Board Member
JACC
2017-present Guest Editor
JACC
2007-present Editorial Board Member
JCMR
2017-present Guest Editor
JCMR
2007-2015
Editor, Diagnostic and Therapeutic Intervention Circulation
Section
2008-present Editorial Board Member
Circulation Cardiovascular Imaging
2008-present Editorial Board Member
JACC Cardiovascular Imaging
2012-2015 Senior Guest Editor
JACC Cardiovascular Imaging
2016-present Associate Editor
JACC Cardiovascular Imaging
Honors and Prizes
1985 2008
Chias Knowlton Scholarship Fellow
University of Toronto, Canada American College of Cardiology (FACC)
5
2008 2010 2011 2012 2013 2019
Mentor, Early Career Award in Clinical Translational Research Mentor, Early Career Award in Clinical Translational Research Co-Mentor, Early Career Award in Basic Research Mentor, Finalist to Early Career Award in Clinical Research HMS Leadership Development for Physicians and Scientists Society for Cardiovascular Magnetic Resonance
SCMR
SCMR
SCMR
SCMR
HMS
Presidential Award (An Award Bestowed for Dedication and Sustained Service to SCMR in Advancing CMR towards Patient Care)
Report of Funded and Unfunded Projects
Funding Information
Past 2004-2007
Competent/Amadeus Trial, Cardiac Multi-detector Computed Tomography Core Laboratory Cardiac Dimensions® Director of Cardiac MRI core laboratory (PI: Scott Solomon) The major goal of this study was to perform core laboratory analyses of cardiac multidetector computed-tomography regarding appropriateness and safety of percutaneous mitral annuloplasty for patients with symptomatic moderate to severe mitral regurgitation.
2007-2010
Characterizing Carotid Plaque Inflammation and Neovascularization by MacrophageTargeted 3D High Field MRI and Contrast Enhanced Ultrasound in Patients and Compare to Histological Quantitative Analyses Donald W. Reynolds Foundation Grant Investigator (PI: Peter Libby) The major goal of this study was to quantify the region and extent of carotid plaque inflammation in patients using a novel MRI contrast enhanced dynamic technique and compare against histology and PET Flurodeoxyglucose (FDG) imaging.
2007-2010
Aliskiren on the Prevention of Left Ventricular Remodeling in High Risk Post-acute Myocardial Infarction (ASPIRE): Cardiac Magnetic Resonance Core Laboratory Novartis Pharmaceuticals Corporation Director of Cardiac MRI core laboratory (PI: Scott Solomon)
6
The major goal of this multicenter multinational study was to perform core laboratory analyses of cardiac MRI regarding cardiac remodeling and any modification from Aliskiren in patients who had experienced a high-risk myocardial infarction (MI).
2008-2013
Adjustable and Measurable Ventricular Restraint for Heart Failure NIH/NHLBI R01 HL090862-01 Co-Investigator (PI: Frederick Chen) The major goal of this study was to assess the feasibility and benefits of a cardiac constraint device against post-MI ventricular expansion. I was responsible for proper data acquisition, post-processing, and measurements from all cardiac MRI images.
2008-2013
Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease NIH/NHLBI R01HL 087060-01 Investigator (PI: Gail Adler) The major goal of this study was to use a novel MRI technique we developed in quantifying myocardial fibrosis due to diabetes and assessing for any beneficial role of mineralocorticoid receptor inhibition in reversing myocardial fibrosis in patients.
2008-2014
Prognostic Impact and Arrhythmic Potential of Peri-infarct Zone by Cardiac MRI NIH/NHLBI R01 HL091157-01 PI This 5-year study extended our previous work that infarct tissue characteristics and remodeling changes quantified by cardiac MRI predict arrhythmia and major cardiac events. This double-blind randomized study assessed infarct characteristics and effects from fish oil supplements in 414 MI patients through a new collaboration between BWH, Massachusetts General Hospital (MGH), and the Beth Israel Deaconess Medical Center (BIDMC).
2009-2012
Recovery Act Supplement Award, Prognostic Impact and Arrhythmic Potential of Periinfarct Zone by Cardiac MRI NIH/NHLBI R01 HL091157-02S1 PI The major goal of this study was to provide administrative support and develop evidence of high-risk biomarkers in parents enrolled in the parent grant R01 HL091157-01.
2010-2014
Novel Magnetic Resonance Imaging of Myocardial Fibrosis NIH R01HL090634 Co-Investigator (PI: Michael Jerosch-Herold) The major goal of this study was to quantify myocardial fibrosis developed as a result of pressure loading of the left ventricle in patients with severe aortic stenosis. The results also provided new insights in future surgical planning of aortic stenosis.
2011-2013 Diagnostic and prognostic values of Regadenoson stress cardiac magnetic resonance
7
(CMR) perfusion imaging in patients with suspected coronary artery disease (REGA11F04) Astellas Pharmaceuticals PI The major goal of this Phase 4 drug trial was to assess if the widespread use of regadenoson vasodilating stress is providing similar or better risk assessment of patients who have symptoms suspected of myocardial ischemia.
2011-2016
Blood Pressure in Dialysis Patients NIH/NIDDK 1RO1DK083424-01A1 Co-Investigator, Cardiac MRI core laboratory Director (PI: Philip Zager) The major goal of this multicenter study was to perform core laboratory analyses of cardiac MRI in patients with end-stage renal failure, to determine if tight blood pressure control will result in beneficial regression of left ventricular hypertrophy.
2012-2016
Improved Arrhythmia Imaging with MR Compatible 12-lead Electrocardiography (ECG) NIH R03 EB013873-01A1 Co-Investigator (PI: Ehud Jeruham Schmidt) The major goal of this study was to investigate the clinical effectiveness of an ECG filtering system our group developed, that eliminate the gating mis-triggering caused by the magnetohydrodynamic effects from aortic blood flow.
2013-2017
ALN-TTRSC-002 (A Phase 2, Open-Label Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Exploratory Clinical Activity of ALN-TTRSC in Patients with Transthyretin (TTR) Cardiac Amyloidosis. Alnylam Pharmaceuticals Co-PI and Director of Cardiac MRI Core Laboratory (Co-PI: Scott Solomon) The major goal of this multicenter study was to use cardiac MRI to assess for any therapeutic effects from ALN-TTRSC, by quantifying changes in myocardial extracellular volume fraction.
2014-2016 Small Business Innovation Research (SBIR) EXACT-COST Trial (Ohio State University) EXCMR, Ltd. Site PI (Overall PI: Orlando Simonetti) The major goals of this study were to investigate the clinical effectiveness of a MRI compatible exercise stress treadmill testing in the detection of myocardial ischemia and the cost effectiveness of this approach in guiding the utilization of downstream invasive catheterization.
2015-2017
ALN-TTRSC-004 (A Phase 3, Open-Label Randomized Control Multicenter Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Exploratory Clinical Activity of ALN-TTRSC in Patients with Transthyretin (TTR) Cardiac Amyloidosis. Alnylam Pharmaceuticals
8
Current 2013-2019
Co-PI and Director of Cardiac MRI Core Laboratory (Co-PI: Scott Solomon) The major goal of this multicenter study was to use cardiac MRI to assess for any therapeutic effects from ALN-TTRSC, by quantifying changes in myocardial extracellular volume fraction.
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA Trial). NIH/NHLBI 4U01HL105561-06 Investigator and Director of Cardiac MRI Core Laboratory (PI: Leslee Shaw)
The major goal of this multicenter multinational study is to assess if any or all of 3 major imaging strategies that guide subsequent invasive coronary intervention will lead to an improved patient outcome. I am conducting the cardiac MRI core laboratory in conjunction with the Montreal Heart Institute.
2013-2019
Plasma miRNA predictors of adverse mechanical and electrical remodeling after MI. NIH/NHLBI 1UH2 TR000901. Co-PI (Co-PIs: Saumya Das, Anthony Rosenzweig, Marc Sabatine) Total direct costs The major goals of this multicenter collaborative study were to develop and validate micro-RNA biomarkers for left ventricular mechanical failure and sudden cardiac death after acute myocardial infarction. This project extends the knowledge gained from the NIH-funded study RO1 HL091157-01 which I am the PI.
2013-2019
Novel Markers of Prognosis in Hypertrophy Cardiomyopathy (HCMR) NIH/NHLBI 5U01HL117006-05 Executive Committee Member, Director of Cardiac MRI Core Laboratory (Co-Pis: Chris Kramer, Stefan Neubauer) Cardiac MRI Core lab budget The main goal of this multicenter study is to characterize the structural cardiac changes in risk stratification of 2,750 HCM patients over a period of 4 years.
2014-2019
SCMR Global Registry Society for Cardiovascular Magnetic Resonance (SCMR) PI and Chair of Registry Steering Committee Total Direct Budget This is an effort provided to build the infrastructures of an international data and imaging registry in CMR.
2016-2019
The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Global Registry Multicenter Study. SCMR (Sponsors: Siemens Medical Systems and Bayer Pharmaceuticals) PI
9
Total Direct Budget This is a 13-center multicenter study with a target enrollment of 2,200 patients that tests the hypothesis that stress CMR performed in real-world setting provides cost-effective noninvasive assessment of patients with chest pain syndromes. Funding Source:
2016-2020
Women's Heart Attack Research Program (HARP): Multicenter Study American Heart Association/New York University School of Medicine Co-Investigator and Director of Cardiac MRI Core Laboratory (PI: Harmony Reynolds) Total Direct Budget This is an observation study evaluating the various causes of patients who experienced an MI without obstructive coronary artery disease (MINOCA).
2016-2020
Treating Ventricle and Valve: New Synergies For Ischemic LV Remodeling With MR NIH 1R01HL128099 Co-Investigator (PI: Robert Levine, Roger Hajjar) This is an animal study evaluating morphological changes of mitral valve with or without the effects of leaflet fibrosis.
2016-2020
Mineralocorticoid Receptor Antagonism for Cardiovascular Health in HIV. The MIRACLE HIV Study. NIH R01DK049302 Co-Investigator (PI: Steven Grinspoon, Gail Adler) This is a 12-month randomized, placebo-controlled study enrolling HIV-infected individuals to characterize the change in cardiovascular physiology as assessed by CMR to treatment with Eplerenone
2016-2020
Molecular Imaging of Primary Amyloid Cardiomyopathy NIH/NHLBI R01HL130563 Co-Investigator (PI: Sharmila Dorbala) This study (NCT02641145) serially image patients with primary light chain amyloidosis (AL) with MRI and PET before and after chemotherapy with the goal of improving our current understanding of AL amyloid cardiomyopathy. The results of these studies may form the foundation for drug discovery programs to prevent and cure this condition.
2017-2021
STOP-CA: Statins to Prevent Cardiotoxicity from Anthracyclines NIH 5R01HL130539-02 Co-Investigator (Co-Pis: Tomas Neilan, Marielle Scherrer-Crosbie) Total Direct Costs: This study evaluates the extent and severity of myocardial inflammation as a result of anthracyclines cardiac toxicities and its progression to diffuse myocardial fibrosis
2017-2022 Open-Label Multicenter Trial GSK 201464 GlaxoSmithKline
10
PI and Director of Cardiac MRI Core Laboratory Total Direct Budget A phase 2 clinical study of GSK2398852 administered following and together with GSK2315698 in cohorts of patients with cardiac amyloidosis.
2017-2022
MYK-461-005 (EXPLORER-HCM) MyoKardia Inc. Director of Cardiac MRI Core Laboratory Total Direct Budget A Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate Mavacamten (MYK-461) in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy.
2018-2021
MYK-461-007 (EXTENSION-HCM) MyoKardia Inc. Director of Cardiac MRI Core Laboratory Total Direct Budget A Follow-up Study using Cardiac MRI to Assess the Therapeutic Responses of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy.
Report of Local Teaching and Training
Teaching of Students in Courses
HMS 2002-2003
Introduction to Clinical Methods
HMS
Second Year Medical Students
4 hours/year for 1 year
Taught 6 medical students and assessed their
skills in obtaining medical history and
performing physical examination
2002-2003
Human Systems Module I:
HMS
Respiratory/Cardiovascular Section
2 hours/year for 1 year
First Year Medical Students
Taught 25 medical students in 2-hour session
on cardiopulmonary physiology
Formal Teaching of Residents, Clinical Fellows and Research Fellows (post-docs)
2001-present Cardiac magnetic resonance imaging
BWH
11
2009-2010
4-5 Fellows in Cardiology or Radiology, 1-2 Residents in Radiology, and occasionally 1 Medical Student per year Didactic teaching session in Cardiovascular Imaging to Medical Students of HMS (course RD500M.23)
8-10 hours
HMS 2 hours per year
Clinical Supervisory and Training Responsibilities
2001-2006
Attending reader, Clinical echocardiography/BWH Supervision of fellows in performance and interpretation of transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and stress echocardiographic studies; reviewed echocardiographic findings in detail of 5-10 TTE studies, and 2-5 TEE, with 1 or 2 fellows in each session.
4-8 sessions per month
2001-present Supervision of all clinical activities of CMR fellows in 15-25 hours per week training and clinical studies interpretation/BWH
2003-2008
Radiology, Cardiac Computed Tomography (CT)/BWH Supervision of fellows in performance and interpretation of all clinical cardiac CT cases
1 day per week
2003-2011
Radiology, Nuclear Cardiology/BWH Supervision of fellows in performance and interpretation of all clinical stress nuclear single-photon emission computed tomography (SPECT) and Positron Emission Tomography (PET) imaging
1 day per week
2007- 2008 Supervision of medical student as part of HMS mentoring 30 hours per year program/BWH 2008-present Supervision of 3 faculty (1 from Cardiology and 2 from 1-2 hours per week
Radiology) in clinical performance of CMR
Laboratory and Other Research Supervisory and Training Responsibilities (Selected Major Activities Only)
2001-present
Supervision of 18 clinical or research fellows in Cardiology conducting cardiac MRI related research projects. This includes 3 cardiology fellows supported by the T-32 training grant. My supervisory roles with these fellows last from 1-3 years. I provide various levels of mentorship (from daily to weekly) on many issues related to their career development, including support in grant writing, job search, and providing informal advice.
12
2001-present
Supervision of 4 clinical or research fellows in Radiology conducting cardiac MRI related research projects. My supervisory roles with these fellows are in general 1 year. I provide mentorship to these fellows on issues related to their career development including manuscript writing, formulation of research ideas, and job search. I also advise the fellows as they embark on starting their own cardiac MRI programs after receiving training from me.
2013-present Mentorship of approximately 20 HMS medical students at Asian Pacific Medical Student Association Mentorship Annual Dinner. 3 hours per year.
Mentored Trainees and Faculty 2003-2004 Servet Tatli, MD / Private practice, Allentown, PA.
Career stage: attending Radiologist. Mentoring role: fellowship mentor. Accomplishments: Published 2 first-authored manuscripts.
2003-2004
Anna K. Y. Chan, MBBS / Associate Physician, Division of Cardiology, Department of Medicine. Associate Professor of Medicine, The Chinese University of Hong Kong. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 1 peer-reviewed paper in Circulation.
2004-2005
Carmen W. S. Chan, MBBS / Associate Physician, Division of Cardiology, Department of Medicine, Associate Professor of Medicine, Hong Kong University. Career stage: Section Director, attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 2 peer-reviewed papers in Circulation.
2004-2006
Andrew T. Yan, MD, FRCPC / Associate Professor, Division of Cardiology, Department of Medicine, University of Toronto, Canada. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Received a 2-year training grant from the Canadian Institutes of Health Research (CIHR); published 2 manuscripts, including first-authored peerreviewed papers in Circulation and the JCMR.
2005-2006
Eric Larose, MD, FRCPC / Associate Professor, Laval University Medical School, Quebec City, Canada. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 2 manuscripts, including 1 first-authored and peerreviewed in JACC.
2005-2007
Maung Khin, MD / Assistant Professor, University of South Florida, Tampa, FL. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 2 manuscripts, including 1 first-authored.
13
2006-2007 2006-2007 2006-2007 2006-2007 2007-2008 2007-2008 2008
Afshin Farzaneh-Far, MD / Director of Cardiovascular MRI, Associate Professor of Clinical Medicine & Radiology, University of Illinois at Chicago. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 4 manuscripts including 1 peer-review in JACC Cardiovascular Imaging.
Kevin Steel, DO / Associate Professor, Uniformed Services University of the Health Sciences, San Antonio, Texas. Career stage: attending cardiologist, Director of Cardiovascular Imaging. Mentoring role: fellowship mentor. Accomplishments: Published 4 first-authored manuscripts, including 1 peer-reviewed original research paper in Circulation.
Hamid Sattar, MD / Assistant Professor of Medicine, Wayne State University School of Medicine, Detroit, MI. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 1 manuscript in Circulation; recipient of the Clinical Early Career Award of the Society of Cardiovascular Magnetic Resonance (SCMR).
Mouaz Al-Mallah, MD / Associate Professor of Medicine, Wayne State University, Detroit, MI; Consultant Cardiologist and Division Head, Cardiac Imaging, King AbdulAziz Cardiac Center, King Abdul-Aziz Medical City complex (Riyadh), Saudi Arabia. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 2 first-authored manuscripts.
Nicolao Tzemos, MD / Professor of Medicine, University of Western Ontario, Ontario, Canada. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 1 first-authored manuscript.
Henry Wu, MD / Assistant Professor in Medicine, Mount Sinai Hospital/School of Medicine, New York, NY. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 2 manuscripts, 1 of them first-authored.
Caroline Daly, MD / Assistant Professor of Medicine, St. James's Hospital, University of Dublin Trinity College, Ireland. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 2 first-authored manuscripts.
2008-2009
Sanjeev Francis, MD / Associate Professor in Medicine, Director of Education, Cardiovascular Institute, Director, Cardiovascular Disease Fellowship Program, Maine Medical Center
14
2008-2009 2008-2009 2008-2009 2008-2010 2009-2011
2009-2011
Career stage: attending cardiologist, Director of Medical Education. Mentoring role: research mentor. Accomplishments: Published 1 first-authored manuscript; finalist for Clinical Science Early Career Award during the Annual Scientific Meeting of the SCMR 2012.
Judith L. Meadows, MD / Assistant Professor of Medicine, Yale University School of Medicine, New Haven, Connecticut. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 2 manuscripts, 1 first-authored.
Edward Hsiao, MD / Associate Professor of Radiology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland OH. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Finalist for Early Career Award during the 2010 Society for Cardiovascular Magnetic Resonance(SCMR) Annual Scientific Meeting.
Krishna Nallamshetty, MD / Associate Professor of Radiology, University of South Florida, Tampa, FL. Career stage: attending radiologist, Director of Cardiovascular Imaging. Mentoring role: fellowship mentor. Accomplishments: Published 1 manuscript in Heart Failure Clinic of North America.
Shuaib M. Abdullah, MD / Assistant Professor of Medicine, University of Texas Southwestern Medical Center, Dallas. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Published 3 manuscripts including 2 in Circulation and 1 in JACC Cardiovascular Imaging
Otavio Coelho-Filho, MD / Associate Professor of Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, Brazil. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Published 6 manuscripts, 4 first-authored, including 1 in JACC Cardiovascular Imaging; recipient of 2011 Clinical Early Career Award of the SCMR; 11 abstract presentations; recipient of the 2012 Basic Science Early Career Award during the SCMR Annual Scientific Meeting.
Eri Watanabe, MD, PhD / Associate Professor of Medicine, Tokyo Women's Medical University, Japan Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: 2 abstract presentations; Finalist for SCMR Early Career Award 2011.
15
2010-2011
Francois-Pierre Mongeon, MD / Associate Professor of Medicine, Université de Montréal, Montreal Heart Institute, Canada. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: One first-authored manuscript in JACC Cardiovascular Imaging; 3 abstract presentations.
2010-2011 Damien Mandry, MD / Associate Professor of Radiology, Nancy University Hospital, Nancy, France. Career stage: attending radiologist. Mentoring role: research mentor. Accomplishments: 2 abstract presentations.
2010-2011
Yu-Cheng Chen, MD / Assistant Professor, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: 1 abstract presentation.
2010-2013
Tomas Neilan, MD / Assistant Professor of Medicine, HMS. Faculty of Department of Cardiology at Massachusetts General Hospital. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: 3 abstract presentations; received a 5-year AHA National Fellow-toFaculty Transition Award. 8 first-authored manuscripts in JAHA, AJC, JACC, and JACC Cardiovascular Imaging. Award recipient of the NIH/NHLBI K-23 Mentored Patient-Oriented Research Career Development Award in 2013.
2010-2014
Bobak Heydari, MD, MPH / Assistant Professor of Medicine, University of Calgary, Canada. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: Received training award from The Alberta Foundation for Health Research (a Canadian non-profit charitable funding agency that supports selected health research); published 4 manuscripts, including 1 in JACC Cardiovascular Imaging; MPH at HSPH. Provided 2 oral abstract presentations at international meetings. Junior faculty position at University of Calgary 2014.
2011-2013
Ravi Shah, MD / Instructor of Medicine, HMS. Faculty of Department of Cardiology at Massachusetts General Hospital. Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: Post-Doctoral Fellowship Training Award of the American Heart Association 2011-2013; 6 first-authored manuscripts in Radiology, Circulation, JAHA, JACC, and JACC Cardiovascular Imaging; finalist for Clinical Science Early Career Award, 2012 SCMR Annual Scientific Meeting.
2011-2014
Siddique Abbasi, MD / Assistant Professor of Medicine, Brown University. Faculty of Department of Cardiology at University Rhode Island Health Service.
16
2013-2014 2013-2014 2014-2017 2015-2016 2015-2016 2015-2017 2016-2017 2016-2018
Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: 1 abstract presentation; best abstract award at the Massachusetts Chapter of the American College of Cardiology 2012 Annual Meeting.
Hui Liu, MD / Assistant Professor, Department of Radiology, Guangdong General Hospital, Guangzhou, China. Career stage: attending radiologist. Mentoring role: research mentor. Accomplishments: 1 manuscript in Circulation CV imaging and 2 case reports
Jonathan Yuan-Hsiang Juan, MD / Assistant Professor, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou and Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan Career stage: attending radiologist. Mentoring role: research mentor. Accomplishments: first-authored a manuscript in Circulation CV Imaging
Tomas Vita, MD, MPH / Departamento de Resonancia Cardíaca-ELAS Career stage: attending cardiologist. Mentoring role: fellowship mentor. Accomplishments: first-authored 1 manuscript in Circulation CV Imaging and another in JACC CV Imaging; MPH from HSPH
Loïc Bière, MD / Assistant Professor, Cardiovascular Section, Department of Medicine, Angers Centre Hospitalier Universitaire, Angers, France Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: first-authored 1 manuscript in JACC CV imaging and co-authored 1 manuscript in JACC
Gokturk Ipek, MD / Assistant Professor, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Internal Medicine, Istanbul, Turkey Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: 1 manuscript in review.
Antonildes Nascimento Assunção Junior, MD / Assistant Professor, University of São Paulo, Internal Medicine, São Paulo, Brazil. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: 1 manuscript in review.
Christoph Gräaeni, MD / Assistant Professor of Medicine, Department of Medicine, University Hospital Bern and University Hospital Zurich, Zurich, Switzerland. Career stage: attending cardiologist. Mentoring role: research mentor. Accomplishments: first-authored 1 peer-reviewed manuscript in JACC; 2 other firstauthored manuscripts in review.
Kana Fujikura, MD, MPH / Clinical Fellow on T32 training grant, Radiology, BWH.
17
2016-2018
Staff Physician Scientist, Laboratory of Cardiac Energetics, NHLBI/NIH, Bethesda, MD Career stage: staff physician scientist. Mentoring role: fellowship mentor. Accomplishments: MPH from HSPH, multiple manuscripts in review
Kyoichi Kaneko, MD / Research Fellow, Cardiovascular Division, BWH Career stage: fellow. Mentoring role: research mentor. Accomplishments: co-authored 1 peer-reviewed manuscript in JACC, 1 peer-reviewed manuscript in JACC CV Imaging, and several other manuscripts in review including 1 first-authored
Formal Teaching of Peers (e.g., CME and other continuing education courses) No presentations below were sponsored by outside entities.
2002
Update on Cardiac Magnetic Resonance Imaging, Radiology Single presentation
Chest Course, BWH
Maui, HI
2003-present (every other year)
Cardiovascular Medicine: Review and Update for the Practitioner Breakout Session, Magnetic Resonance Imaging, BWH
Single presentation Boston, MA
2015-2018 (every other year)
Clinical Applications of Cardiac Magnetic Resonance Imaging Single presentation
Brigham Board Review in Cardiology, BWH
Boston, MA
Local Invited Presentations No presentations below were sponsored by outside entities.
2001
Detecting Acute Coronary Syndrome in the Emergency Department with Cardiac Magnetic Resonance Imaging / Cardiac MRI Seminar Beth Israel Deaconess Medical Center (BIDMC), Boston, MA.
2002
Detecting Acute Coronary Syndrome in the Emergency Department with Cardiac MRI / Grand Rounds in Cardiology BIDMC (West)
2002
Detecting Acute Coronary Syndrome in the Emergency Department with Cardiac MRI/ Invited lecture Joint Program in Nuclear Medicine, BIDMC (East)
2002
Myocardial Viability by Cardiac Magnetic Resonance Imaging / Grand Rounds in Radiology
18
MGH
2003
Myocardial Viability / Children's Hospital Cardiac MRI Seminar BWH
2003
Cardiac MRI Stress Testing / Children's Hospital Cardiac MRI Seminar BWH
2005 Use of Cardiac MRI for Evaluation of ACS Patients / Invited lecture TIMI Study Group, BWH
2005
Hybrid PET/CT Technology in Detecting Coronary Artery Disease / Moderating Chair Center for Integration of Medicine and Innovation (CIMIT) Meeting, MGH
2005
Assessment of Myocardial Ischemia and Viability by Cardiac Contrast Enhanced MRI Techniques, CIMIT Meeting Group, Massachusetts General Hospital, Boston, MA.
2005-present Review and Update of the Clinical Applications of Cardiovascular MRI / Grand Rounds Faulkner Hospital, Boston, MA.
2006
Prognostic Role of Delayed Hyperenhancement Imaging in Coronary Artery Disease, MGH Grand Rounds in Cardiology, Massachusetts General Hospital, Boston, MA.
2006
Peri-infarct Zone Characterized by Contrast-Enhanced Cardiac MRI Strongly Predicts Post-MI Mortality, BIDMC Cardiac MRI Seminar, Beth Israel Deaconess Medical Center (West), Boston, MA.
2006
Prognostic Role of Contrast Enhanced Cardiac MRI in Patients Suspected of Coronary Artery Disease (CAD), Beth Israel Deaconess Medical Center (East), Boston, MA
2007
Clinical Updates, New Techniques, and Patient Safety of Cardiac MRI, BWH Grand Rounds in Cardiology, Brigham and Women's Hospital, Boston, MA.
2007
Characterization of Hazards to Post-MI Mortality with Contrast Enhanced MRI / Invited lecture Brigham Research Institute Seminar Series, BWH
2007-present Technical Magnetic Resonance Education Series: BWH Department of Radiology, Brigham and Women's Hospital, Boston, MA.
2007-present BIDMC Cardiac MRI Seminar: Stress Cardiac MRI and Clinical Application, Beth Israel Deaconess Medical Center (West), Boston, MA.
19
2007-present Brigham Research Institute Research Retreat Session, Brigham and Women's Hospital, Boston, MA.
2010-present Role of Cardiac MRI in Clinical Trials and Novel Therapy Assessment, V.A. Medical Center, West Roxbury, MA
2011
Shaping the Future of Cardiac Magnetic Resonance Imaging in an Era of Cost Containment, Faulkner Hospital Grand Rounds in Cardiology, Faulkner Hospital, Boston, MA.
2011-present Presenter and Co-Moderator, First Semi-Annual Research Retreat of Non-Invasive Cardiovascular Imaging. Department of Radiology and Department of Medicine, BWH.
2012
Diagnosing Cardiac Sarcoidosis: A Mini Debate. Cardiovascular Imaging Grand Rounds, Department of Radiology and Department of Medicine, BWH.
2013
How to properly interpret stress CMR Imaging of Patients with CAD. Cardiovascular Imaging Grand Rounds, Department of Radiology and Department of Medicine, BWH.
2014
Harvard Catalyst Imaging in Clinical Translational Cardiovascular Research
2015
Research in Progress Seminar: The Trial Design and Preliminary Results of the OmegaRemodel Study. Department of Radiology and Department of Medicine, BWH.
2015
Clinical-Pathology Conference: Department of Medicine: A case report of a patient with deafness and heart failure. Department of Medicine, BWH.
2016
Fellowship Teaching Rounds: A Review of Clinical Applications Cardiovascular Medicine Division, Department of Medicine, BWH
2017
How to Find Funding Sources: The Art and Anatomy of Writing a Career Development Grant. Research Education Program, BWH. [Invited Lecture]
2018 2018
How CMR Improves Heart Failure Management: A Clinical Update. Heart Failure Section, Massachusetts General Hospital, Boston [Invited Lecture] Creation of the SCMR Registry and the Multicenter Stress Perfusion Imaging in the United States (SPINS) Study. Noninvasive Cardiovascular Imaging Section, Brigham and Women's Hospital
Report of Regional, National and International Invited Teaching and Presentations
Invited Presentations and Courses
20
No presentations below were sponsored by outside entities Regional 2001-present Clinical Applications of Cardiac Magnetic Resonance Imaging, Leonard Morse Hospital, (every other Natick, MA [Grand Rounds in Cardiology] year)
2009
Advanced Cardiac Imaging as a Tool in Clinical Research, The 23rd Northeast Region Conference and Exhibition (NERCE) meeting, Boxborough, MA. [Invited Lecture]
2009
Cardiac Prognostication by Contrast-enhanced Cardiac Magnetic Resonance Imaging, Brown University Medical School/Rhode Island Hospital, Providence, RI [Rhode Island Medical Center Visiting Professorship]
2010
Planning of the Future of Cardiac Magnetic Resonance Imaging, Grand Rounds in Cardiology, Tufts Medical Center, Boston, MA. [Invited Lecture]
2013
Clinical Applications of Cardiac Magnetic Resonance Imaging: South Shore Medical Center Attending: 30 participants, 2 hours contact time
2014
Current Clinical Applications of Cardiac MRI Cape Cod Hospital [Grand Rounds in Cardiology]
2015
Cardiology Grand Rounds: The Clinical role and Impact of Stress CMR Myocardial Perfusion Imaging: What it is practical and clinically relevant. Boston University Medical Center, Boston, MA [Invited Lecture]
2019
Keynote Presentation: Northeast Ohio Medical University, Harvey Lecture: Cardiology: The Next Thirty Years. Kent, Ohio [Invited Lecture]
National 2001
2001
2003
Current Clinical Applications of Cardiac Magnetic Resonance Imaging, Grand Rounds in Radiology, George Washington University Medical Center, Washington, DC. [Invited Lecture]
Grand Rounds in Cardiology: Current Cardiac MRI Assessment of Ischemia Heart Disease, George Washington University Medical Center, Washington, DC. [Invited Lecture]
Dobutamine Stress Function and Perfusion Imaging, Fourth International Workshop on Coronary MR and CT Angiography, The North American Society for Cardiac Imaging (NASCI), Dallas, TX. [Invited Lecture]
21
2003 2004 2004
2005 2005 2005 2006
2006
2006 2006 2006 2006 2007
Magnetic Resonance Myocardial Perfusion, The 5th Annual Cardiovascular Magnetic Resonance Imaging Summit, Oklahoma Heart Institute, Tulsa, OK. [Invited Lecture]
Characterization of Cardiac Inflammation in Cardiac Transplantation, University of Minnesota, Minneapolis, MN. [Visiting Professorship]
Characterization of Cardiac Inflammation in Allograft Rejection, Carnegie Mellon University/Pittsburgh NMR Center for Biomedical Research, Pittsburgh, PA. [Research Grand Rounds]
How to Set Up an Efficient Clinical Cardiac MRI Service? George Washington University Medical Center, Washington, DC. [Grand Rounds in Cardiology]
Managing Chest Pain in the ER with Cardiac MRI, AHA Annual Scientific Sessions, Dallas, Texas [Invited Lecture]
How to Combine Diagnostic Information from Cine, Perfusion, and Delayed Imaging, SCMR Annual Scientific Sessions, San Francisco, CA.[Plenary Presentation]
Peri-infarct Characterization by Cardiac MRI and Post-Myocardial Infarction Mortality, New York Presbyterian Hospital/Cornell University, New York, NY. [Grand Rounds in Cardiology]
Characterizing Patient Risk from Coronary Artery Disease (CAD) with Contrast Enhanced Cardiac MRI, Wake Forest School of Medicine, Winston Salem, NC. [Grand Rounds in Cardiology]
Current Applications of Cardiac MRI and CT, 12th Annual Interventional Cardiology Fellow Course, Cardiovascular Research Foundation, San Jose, CA. [Invited Lecture]
Cardiac MRI Case Symposium: ACC 2006 Scientific Sessions, Atlanta, GA. [Invited Lecture]
Dobutamine Stress Cardiac Magnetic Resonance Imaging, AHA Annual Scientific Sessions, Chicago, IL. [Invited Lecture]
Prognostic Implication of Late Gadolinium-Enhanced Cardiac MRI, AHA Annual Scientific Sessions, Chicago, IL. [Invited Lecture]
When is Cardiac MRI the Imaging Test of Choice? ACC Annual Scientific Meeting, New Orleans, LA. [Invited Lecture]
22
2007 2007 2007 2007
2007 2007 2007 2007 2007 2007 2007 2008 2008
Role of Cardiac MRI in Heart Failure. ACC Annual Scientific Meeting, New Orleans, LA. [Invited Lecture]
Current Clinical Roles of Cardiac MRI and CT Imaging, University of Rochester Medical Center, Rochester, NY. [Cardiology Division Grand Rounds]
Toshiba 256 Detector Cardiac Computed Tomography User Meeting, Toshiba Medical Imaging, Washington, DC. [Other] (Sponsored by Toshiba but I did not receive any honorarium for participating in this meeting.)
MRI Stress Testing and Viability. Review of the Current Medical Literature and Clinical Cases, Scripps Clinic Medical Center Continuing Medical Educational Program in Cardiac MRI, Scripps Clinic Medical Center, La Jolla, CA. [Invited Lecture]
Role of Advanced Cardiac Imaging in Management of Diabetic Patients, American Diabetes Association Annual Scientific Meeting, Chicago, IL. [Invited Lecture]
Viability Assessment in Clinical Practice, ACC Annual Scientific Meeting, New Orleans, LA [Invited Lecture]
What is the best test in evaluating acute coronary syndromes? An evidence based debate, Transcatheter Cardiovascular Therapeutics (TCT) Annual Scientific Meeting, Washington, DC [Invited Lecture]
MR workstation demonstration: Cardiac MRI Perfusion, TCT Annual Scientific Meeting, Washington, DC.[Invited Lecture]
Cardiac MRI myocardial perfusion: techniques and interpretation--a current review, TCT Annual Scientific Meeting, Washington, DC.[Invited Lecture]
Clinical cases of MRI assessment of chest pain patients, TCT Annual Scientific Meeting, Washington, DC.[Invited Lecture]
How to Integrate Radiology and Cardiology in Cardiac MRI/CT, AHA Annual Scientific Sessions, Orlando, FL.[Invited Lecture and Moderating Chair]
Technical Panel Participant as the SCMR Representative: Appropriateness Criteria for Cardiac Radionuclide Imaging. SCMR/ACC meeting, Chicago. IL. [Seminar]
GE Healthcare Cardiac MRI Medical Advisory Board Meeting. GE Healthcare, Milwaukee, WI. [Invited Lecture] (Sponsored by GE Healthcare but I did not receive any honorarium for participating in this meeting.)
23
2008 2008 2008 2008
2008 2008 2008 2009 2009 2009
2009 2010 2010
Assessment of Myocardial Viability by Cardiac MRI, ACC Annual Scientific Sessions Integrated Imaging Sessions, Chicago, IL. [Invited Lecture]
Potential Utility of Newer Imaging Modalities, ACC Annual Scientific Sessions Integrated Imaging Session, Chicago, IL. [Invited Lecture]
Cardiac MRI Case Review Session, Transcatheter Cardiovascular Therapeutics (TCT) Annual Scientific Meeting, Washington, DC. [Invited Lecture]
Cardiac MRI to Access Acute Chest Pain: Advantages and Limitations, Transcatheter Cardiovascular Therapeutics (TCT) Annual Scientific Meeting: Washington, DC. [Invited Lecture]
Role of Cardiac Magnetic Resonance in Determining the Risk of Diabetic Patients, AHA Annual Scientific Sessions, New Orleans, LA. [Invited Lecture]
Outcomes in Acute Myocardial Infarction, AHA Annual Scientific Sessions, New Orleans, LA. [Moderating Chair]
Late Gadolinium Enhancement, an Update in its Prognostic Implication, SCMR Annual Scientific Sessions, Los Angeles, CA. [Invited Lecture and Moderating Chair]
Myocardial Ischemia, SCMR Annual Scientific Sessions, Orlando, FL. [Plenary Presentation]
NHLBI Scientific Working Group: Role of Imaging in Risk Stratification of Sudden Cardiac Death, NHLBI/NIH, Washington, DC. [Invited Lecture]
NHLBI/NIH Mark F. Weinstein Memorial Lecture: 10 Years of NIH Translational Research--Cardiac/Stroke Imaging and Therapy (Cardiovascular MRI Outcomes Research--A Powerful Prognosticator), NHLBI/Suburban Hospital, Bethesda, MD. [Invited Lecture]
Sudden Cardiac Death: Grey Zone is the Best Index, SCMR Annual Scientific Sessions, Orlando, FL. [Plenary Presentation]
Cardiac MRI myocardial perfusion and patient prognosis, SCMR Annual Scientific Sessions, Phoenix, AZ. [Invited Lecture]
Cardiac MRI as endpoints for clinical trials, Society of Cardiovascular Magnetic Resonance, SCMR Annual Scientific Session, Phoenix, AZ. [Invited Lecture]
24
2010 2010 2010 2010 2010 2010 2011 2011 2011 2011 2011 2012 2012
Updates in Cardiac MRI 2010: Advanced Cardiovascular Imaging, New York, NY. [Invited Lecture]
The Future of Cardiovascular Magnetic Resonance Imaging in the Current Economic Environment, Departments of Radiology/Cardiology, University of South Florida, Tampa General Hospital, Tampa, FL. [Visiting Professorship]
CMR in acute coronary syndromes: Abstract summary presentation, ACC Annual Scientific Sessions, Atlanta, Georgia. [Invited Lecture]
Cardiac MRI in Patients with Heart Failure: Risk Stratification for Therapy and Prognosis, ACC Annual Scientific Sessions, Atlanta, Georgia. [Invited Lecture]
Cardiac MRI: Insights for Clinical Practice II, Annual Scientific Sessions of the AHA, Chicago, IL. [Moderator for Oral Abstract Session]
Imaging of Heart Failure, Late Gadolinium Enhancement Imaging (LGE) and Strain Imaging (Cardiac MRI/Echo), Annual Scientific Sessions of the AHA, Chicago, IL. [Invited Lecture]
Shaping the Future of Cardiac MRI: What We Have Learned in the Last 10 Years of Cardiovascular Imaging, Northwestern University Feinberg School of Medicine, Chicago, IL.[Grand Rounds in Cardiology]
ACC Meet the Experts: Outcomes and Cost-Effectiveness of CV Imaging, ACC Annual Scientific Sessions, New Orleans, LA. [Invited Lecture]
Myocardial Characterization in CAD: Ventricular Morphology and Delayed Hyper/Hypoenhancement and Heterogeneity, ACC Annual Scientific Sessions, New Orleans, LA. [Invited Lecture]
Appropriate Use of Cardiac MR: How to Apply in Daily Practice, ACC Annual Scientific Sessions, New Orleans, LA.[Invited Lecture]
Ischemia and Beyond Ischemia: CARDIAC MRI Indices of Prognosis, ACC Annual Scientific Sessions, New Orleans, LA [Invited Lecture]
The Fun and Challenges of Building Cardiac MRI: Our Experience from the First 10 Years, University of Pennsylvania Hospital System, Philadelphia, Pennsylvania [Grand Rounds in Cardiology]
Prognostic Impact and Arrhythmic Potential of Peri-infarct Zone by Cardiac Magnetic
25
2012 2012 2012 2013
2013
2013 2013 2013 2013
2013 2014 2014
Resonance Imaging (NHLBI PROSPECT-CMR Study), Health Diagnostic Laboratories, Richmond, Virginia [Invited Lecture]
Plenary session, SCMR Annual Scientific Sessions, Program Orlando, FL.[Program Chair and Moderator of the Opening Plenary Session]
How to Perform Cost-Effectiveness Analyses in Imaging Research, SCMR Annual Scientific Sessions, Orlando, FL [Invited Lecture]
Best Narrated Poster Session, SCMR Annual Scientific Sessions, Orlando, FL [Moderating Chair]
Stress Cardiac Magnetic Resonance Imaging for Ischemic Heart Disease: Why it is an Important Tool Amongst other Noninvasive Tools? New York University Medical Center, New York, NY [Grand Rounds in Cardiology]
Myocardial Scar: In Some Or All? Prognostic Value? Integrated Imaging of Heart Failure for Clinical Decision-Making, ACC Annual Scientific Meeting, San Francisco, CA.[Invited Lecture]
CMR Stress Perfusion: State of the Art. Prognostic Utility. ACC Annual Scientific Meeting, San Francisco, CA.[Invited Lecture]
In Search of the Culprit Lesion: Utility of Imaging: Is there a Role for MRI? AHA Annual Scientific Sessions, Dallas, Texas [Invited Lecture]
Cardiac MRI 2013: Putting Your Best Spin On It: Late Gadolinium Enhancement: Ten Shades of Grey? AHA Annual Scientific Sessions, Dallas, Texas [Invited Lecture]
Risk Stratification in Ischemic and Non-ischemic Cardiomyopathies: From Flow Reserve to Contrast Enhancement, SCMR Annual Scientific Sessions, San Francisco. [Invited Lecture]
Non-ischemic Heart and Multiorgan Diseases, SCMR Annual Scientific Sessions, San Francisco. [Invited Lecture]
The Multicenter Omega-Remodel Randomized Control Trial, University of Minnesota Medical Center, Minneapolis, MN [Grand Rounds in Cardiology]
Cardiac MR and Identification of Mechanisms in ACS Without Obstructive CAD. AHA Annual Scientific Sessions, Chicago, IL [Invited Lecture]
26
2014 2014 2014 2014 2015 2015 2015
2015 2015 2016
2016 2016 2016
Name that CMR Perfusion Defect. AHA Annual Scientific Sessions, Chicago, IL [Invited Lecture]
Imaging Cardiomyopathy, AHA Annual Scientific Sessions, Chicago, IL. [Moderator for Oral Abstract Session]
Global Cardiac Magnetic Resonance Registry (GCMR): Its concepts and planning. SCMR Annual Scientific Sessions, New Orleans, Louisiana. [Invited Lecture]
Challenges of Conducting Imaging-Based Outcome Research. SCMR Annual Scientific Sessions, New Orleans, Louisiana. [Invited Lecture]
Role of CMR in Outcomes of Diabetic Patients, Annual Scientific Sessions of the ACC 2015, San Diego, CA [Invited Lecture]
Imaging Cardiomyopathy, AHA Annual Scientific Sessions, San Diego, CA. [Moderator for Oral Abstract Session]
Stress Cardiac Magnetic Resonance Imaging for Ischemic Heart Disease: why it is a relevant and practical tool? Boston University Medical Center. [Grand Rounds in Cardiology]
Can Fish Oil Heal a Broken Heart? The OMEGA-REMODEL Study. Yale University Medical Center. [Grand Rounds in Cardiology 2015]
Cardiac MRI and the Development of Its Global Registry. University of Maryland Medical Center. [Grand Rounds in Cardiolog]
Can Fish Oil Heal a Broken Heart? The OMEGA-REMODEL Study. Molecular Imaging Program at Stanford (MIPS) Seminar Series. Stanford University Medical Center. [Grand Rounds in Cardiology]
Conference in Heart Failure Management. CMR and Congestive Heart Failure: Current and Future. Stanford University Medical Center. [Invited Lecture]
CMR Quantification in Clinical Research & Diagnosis. 19th SCMR Annual Scientific Meeting, Los Angeles, CA. [Invited Lecture]
Can Fish Oil Heal a Broken Heart? The OMEGA-REMODEL Study. University of Utah Medical Center. [Grand Rounds in Cardiology]
27
2016 2016 2016 2017 2017
2017 2017 2017 2017 2018 2018 2019
Can Fish Oil Heal a Broken Heart: A randomized control trial of Omega-3 Fatty Acids in Patients with a Recent Myocardial Infarction. Stanford University Conference in Heart Failure. Stanford, California [Invited Lecture]
Global CMR Registry (GCMR) of SCMR. ACC Annual Scientific Sessions, Chicago, IL [Invited Lecture]
All You Need is Cardiac MRI. Controversies and Advances in the Treatment of Cardiovascular Disease. The Sixteenth in the Series. Beverly Hills, CA [Invited Lecture]
Cardiovascular Magnetic Resonance In the Guidelines: United States. ACC Annual Scientific Session [Invited Lecture]
Can Fish Oil Heal a Broken Heart: A randomized control trial of Omega-3 Fatty Acids in Patients with a Recent Myocardial Infarction. Ohio State University Nutritional Science Section [Invited Lecture]
How Omega-3 Fatty Acid Treatment Affect Post-MI Cardiac Remodeling. Why the Discrepancy Between Outcome Trials? Organized by Wiley Finest Incorporation [Invited Lecture]
A Blinded Core-Lab Imaging Analysis is NOT Essential in Multicenter Clinical Trials. 20th SCMR Annual Scientific Meeting, Washington, DC. [Invited Lecture]
How Can Cardiac MRI Survive in a Multimodality Environment of Cardiac Imaging? 20th Annual SCMR Level I Course. Washington, DC [Invited Lecture] Personalized Drug Discovery Towards Better Infarct Healing. Saint Francis Hospital Cardiology Grand Rounds. Long Island, New York [Invited Lecture]
The Role of Genotype Polymorphism and Systemic Inflammation Towards Promotion of Infarct Healing with Omega-3 Fatty Acids. Iowa University, Iowa City [Cardiology Grand Rounds]
Personalized Medicine to Improve Infarct Healing: Lessons from the OMEGAREMODEL Trial. New York University, New York [Cardiology Grand Rounds]
The SCMR Registry and the SPINS Study. The 20th SCMR Annual Scientific Meeting, Seattle, Washington. [Opening Plenary]
28
2019
What are the CMR Indications in the Real-world, Lessons Learned from the SCMR Registry. The 20th SCMR Annual Scientific Meeting, Seattle, Washington. [Invited Lecture]
International
2004
SCMR Invited Panel Discussion: Clinical case reports in cardiac MRI, Society of Cardiovascular Magnetic Resonance, Barcelona, Spain [Invited Lecture]
2004
Stress Cardiac Magnetic Resonance, ISMRM 12th Scientific Meeting Weekend Educational Program, Kyoto, Japan [Invited Lecture]
2004
CV MRI Study Group: Controversy in Myocardial Viability, ISMRM 12th Scientific Meeting Weekend Educational Program, Kyoto, Japan [Invited Lecture]
2005
Status of Clinical MRI Perfusion Compared to Nuclear Imaging: Experience from a Tertiary Care Center, Multicenter MRI Perfusion Study Meeting Group, General Electric Healthcare, London, England [Invited Lecture]
2006
Cardiac MRI is Better for Assessing Patients with Congestive Heart Failure, Severance Cardiovascular Imaging Symposium, Yonsei University College of Medicine, Seoul, South Korea [Invited Lecture]
2006
Cardiac MRI Delayed Hyperenhancement Imaging for Myocardial Viability, Severance Cardiovascular Imaging Symposium, Yonsei University College of Medicine, Seoul, South Korea. [Invited Lecture]
2007
Small Foci of Late Enhancement Without Known MI, Society of Cardiovascular Magnetic Resonance, Rome, Italy. [Plenary Presentation]
2007
Cardiac MRI in Suspected Acute Coronary Syndrome, Society of Cardiovascular Magnetic Resonance, Rome, Italy. [Plenary Presentation]
2007
Fusion of Imaging Technology: 3D, 4D Echo, Cardiac CT and MRI, University of Toronto Fourth Annual Great Debates and Innovations, Mount Sinai Hospital/Toronto General Hospital, Toronto, Ontario, Canada. [Invited Lecture]
2007
Beyond Cardiac Morphology by Echocardiography: The Growing and Complementary Role of Cardiac Magnetic Resonance Imaging, Queen Mary Hospital, Hong Kong University, Hong Kong, China. [Visiting Professorship]
2008
Applications of Myocardial Viability Assessment by Cardiac MRI, International Society of Magnetic Resonance in Medicine meeting, Toronto, Ontario, Canada. [Invited Lecture]
29
2008 2010 2010
2010 2010 2011 2011 2011 2011 2011 2011
Novartis SPP100A2340 (ASPIRE Study) Investigator Meeting, Novartis, Sao Paulo, Brazil. [Invited Lecture] (Sponsored by Novartis, but I did not receive any honorarium for participating in this meeting.)
Myocardial Late Enhancement: Description, Application, and Current Update, Canadian Cardiovascular Society, The 19th Interventional Cardiology Symposium, Montreal, Quebec, Canada [Invited Lecture]
Visiting Professorship, Planning the Future of Cardiovascular Magnetic Resonance: Lessons Learned from the Past Decade, British Heart Foundation/Glasgow Cardiovascular Research Center, University of Glasgow, Scotland. [Visiting Professorship]
Visiting Professorship, Why Cardiac Magnetic Resonance Imaging Is a Practical Tool to Assess Novel Cardiovascular Therapies, Golden Jubilee National Hospital/ Glasgow Medical School, Clydebank, Scotland. [Visiting Professorship]
Visiting Professorship, Departments of Cardiology: How Far Have We Gone in Cardiac Magnetic Resonance in the Past 10 Years? Saint James's Hospital, Trinity College, Dublin, Ireland. [Visiting Professorship]
Visiting Professorship, Shaping the Future of Cardiac MRI: What We Have Learned in the Last 10 Years of Cardiovascular Imaging, Montreal Heart Institute, Montreal, Quebec, Canada. [Visiting Professorship]
What Are the Basic Steps in Assessing Cost Effectiveness of Cardiac MRI? SCMR/EuroCMR Joint Scientific Sessions, Nice, France. [Invited Lecture]
Controversies in Cardiac MRI, SCMR/EuroCMR Joint Scientific Sessions, Nice, France. [Moderator: Closing Plenary Session]
Why Cardiac MRI Should Be Our Noninvasive Modality of Choice for Cardiomyopathy of Unknown Etiology, São Paulo Radiology Meeting/Brazil-Chile Congress of Radiology, São Paulo, Brazil. [Invited Lecture]
Ischemic Heart Disease Assessment by Cardiac MRI, São Paulo Radiology Meeting 2011/Brazil-Chile Congress of Radiology, São Paulo, Brazil. [Invited Lecture]
Beyond Delayed Hyperenhancement: The Role of Tissue Characterization, São Paulo Radiology Meeting/Brazil-Chile Congress of Radiology, São Paulo, Brazil. [Invited Lecture]
30
2011 2011 2011
2012 2012 2012 2012 2013 2013 2014
Why Cardiac MRI Should be Utilized in Clinical Trials of Novel Therapy, São Paulo Radiology Meeting/Brazil-Chile Congress of Radiology, São Paulo, Brazil. [Invited Lecture]
A Workshop on Cardiac Magnetic Resonance Imaging Endorsed by the Society for Cardiovascular Magnetic Resonance (SCMR), 5th Congress of the Asian Society of Cardiovascular Imaging (ASCI) 2011, Hong Kong, China. [Course Director]
Perspectives on the Use of Magnetic Resonance Imaging for Coronary Disease, 13th Brazilian Congress of Atherosclerosis, Florianopolis, Santa Catarina. [Invited Lecture] (I could not attend in person due to the unexpected need to have surgery, but I provided my presentation using narrated PowerPoint slides.)
Use of Cardiac MRI in Imaging Myocardial Viability in Patients with Coronary Artery Disease, Medical Imaging of Beijing, First Scientific Session, Symposium in Cardiovascular Medical Resonance Imaging, Beijing, China. [Invited Web Lecture]
Clinical Applications, Novel Therapeutic Trials, and the Future Outlook of Cardiac Magnetic Resonance Imaging In the United States, Chinese Society of Magnetic Resonance in Medicine 2012 Annual Scientific Meeting, Xiamen, China [Invited Speaker and Session Moderator]
Myocardial Applications Using Cardiac Magnetic Resonance Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. [Visiting Professor and Speaker]
Stress Cardiac Magnetic Resonance Imaging: Diagnostic Utility, Cost Effectiveness, and Risk Reclassification Improvement in Coronary Artery Disease, Queen Mary Hospital, Hong Kong University, Hong Kong, China [Visiting Professorship]
Cardiac Magnetic Resonance Imaging Review Course Endorsed by the Society for Cardiovascular Magnetic Resonance (SCMR), Great Wall International Cardiology Convention 2013, Beijing, China. [Course Director]
Why Stress Cardiac MRI Should be Used in Assessing Patients with Suspected Ischemia in the Era of Cost Containment. Irish Cardiac Society Annual Scientific Meeting, Kerry Co, Ireland. [Invited Plenary Speaker]
Imaging of Patients with Arrhythmia and Assisting Radiofrequency Ablation Imaging of cardiomyopathy, Cardiovascular Imaging Symposium Joint HHCC/HHCR/SCMR, Hong Kong, China [Invited Lecture]
31
2014 2014 2014 2014 2014 2014 2014 2014
2014 2014 2015
2015
2015 2015
Imaging of cardiomyopathy, Cardiovascular Imaging Symposium Joint HHCC/HHCR/SCMR, Hong Kong, China [Invited Lecture]
3-day imaging symposium SCMR-Chinese Academic of Science. Shenzhen, Guangzhou, China [Course Organizer and Speaker]
Clinical Frontiers of Cardiac Imaging, International STACOM Boston 2014: Massachusetts Institute of Technology, Boston 2014 [Invited Lecture]
Can Fish Oil Heal a Broken Heart, London CMR Lecture, London Heart Center and St. Bartholomew's Hospital, London, UK [Visiting Professorship]
Can Fish Oil Heal a Broken Heart, the OMEGA-REMODEL Study. Grand Rounds in Cardiology, Oxford University Medical Center [Visiting Professorship]
Joint Symposium in CMR Review, Joint SCMR/Asian Society of Cardiovascular Imaging (ASCI) Annual Scientific Meeting, Jeju, South Korea
Current Status of Heart Failure Imaging, Asian Society of Cardiovascular Imaging (ASCI) Annual Scientific Meeting, Jeju, South Korea [Invited Lecture]
Can Stress CMR Perfusion Imaging Meet the Demands Compared to Other Imaging Options? Asian Society of Cardiovascular Imaging (ASCI) Annual Scientific Meeting, Jeju, South Korea [Invited Lecture]
Can Stress CMR Perfusion Imaging be Cost Effective? Asian Society of Cardiovascular Imaging (ASCI) Annual Scientific Meeting, Jeju, South Korea [Invited Lecture]
Why You Should Develop CMR for Patient Care in China. Guangzhou Province Hospital, Guangzhou, China [Radiology Grand Rounds]
Translating Imaging Technology to Improved Global Outcomes, 18th Annual SCMR/EuroCMR Joint Scientific Meeting, 2015, Nice, France. [Closing Plenary Session Presentation]
How Does Cardiac MRI Survive in a Multimodality Environment: 18th Annual SCMR/EuroCMR Joint Conference Level 1 Course. Nice, France. [Pre-Conference Clinical Course Lecture 1]
CMR for Management of Ischemic Heart Disease. 18th Annual SCMR/EuroCMR Joint Conference Level 1 Course. Nice, France. [Pre-Conference Clinical Course Lecture 2]
Case Review Session. 18th Annual SCMR/EuroCMR Joint Conference Level 1 Course.
32
2015 2015 2016 2017 2017 2017 2018 2018 2018 2018 2018
Nice, France. [Pre-Conference Clinical Course Lecture 3]
Global CMR Registry: An Update, its Successes and Challenges Ahead, 18th Annual SCMR/EuroCMR Joint Scientific Meeting, 2015, Nice, France. [Clinical Trial Workshop,]
How to perform Dobutamine Stress CMR, 18th Annual SCMR/EuroCMR Joint Scientific Meeting, 2015, Nice, France. [Technologist Workshop,]
How Cardiac MRI Can Shape Cardiac Care. The 75th Annual Meeting of the Japan Radiological Society, Yokohama, Japan [Plenary Presentation]
The OMEGA-REMODEL Trial: Rationale and Clinical Impact. The Inaugural Symposium of the International Society of Omega-3 Research, Boston, MA [Invited Lecture]
Is Personalized Reversal of adverse Post MI Remodeling Possible? Department of Clinical Sciences, Lund University, Sweden [Invited Lecture]
Faculty Opponent to PhD Dissertation of Dr. David Nordlund, Department of Clinical Sciences, Lund University, Sweden [Visiting Professorship]
How Imaging Can Become a Key Player in the Future of Clinical Trial and Drug Development. 21st Annual SCMR/EuroCMR Joint Scientific Meeting, Barcelona, Spain. [Invited Lecture]
Personalized Medicine with Omega-3 Fatty Acid Genotype and Metabolomics to Improve Infarct Remodeling: Lessons from the OMEGA-REMODEL Trial. Montreal Heart Institute, Montreal, Quebec, Canada [Cardiology Grand Rounds]
Cardiovascular Imaging: from Structure to Function, Tissue Characterization in the Human Heart. International Society for Magnetic Resonance in Medicine (ISMRM), Paris, France. [Plenary Session]
The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Registry Study. European Society of Cardiology Congress, Munich, Germany [Late-Breaking Science in Imaging Session]
The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Registry Study. American Heart Association Annual Scientific Meeting, Chicago, Illinois
33
Report of Clinical Activities and Innovations
Current Licensure and Certification
1992 1992 1993 1997 1997 1998 1999 2001 2002
Ontario Medical License, Canada Licentiate of Medical Council of Canada Medical License of British Columbia, Canada Diplomate, American Board of Internal MedicineInternal Medicine Medical License of the District of Columbia Diplomate, American Board of Internal MedicineCardiovascular Diseases Maryland Medical License Massachusetts Medical License Course Certificate, Nuclear Cardiology Health and Radiological Seminars, Nuclear Regulatory Commission (NRC)
Practice Activities
2001-2007 Performance and Echocardiography Service, 2 half-day sessions per
interpretation of transthoracic BWH week and transesophageal studies
2002-2010 Inpatient consult
Cardiac Surgery, BWH
2 weeks per year
2007-2012 Performance and Exercise Laboratory and 2 half-day sessions per interpretation
of cardiac Nuclear Cardiology Service, week
nuclear scintigraphy and
BWH
exercise stress testing studies
2001-2017 Outpatient clinic Cardiology, BWH 6 hours per week 2001-
Performance and Cardiology/Radiology,
3 days per week present
interpretation of clinical BWH CMRI studies
2001- Interpretation of clinical Cardiology, BWH 4 sessions per month present
electrocardiography studies
2002- Inpatient attending Cardiology, BWH 4 weeks per year present
2016- Inpatient cardiac and Cardiology, BWH 2 weeks per year present vascular medicine consult
Clinical Innovations
Bridging Novel CMR Technique to Management of Patients with Coronary Artery Disease (2006-present)
Using clinical data from BWH, I described the prognostic utility and management implication of CMR late gadolinium enhancement (LGE) imaging of myocardial infarction in patients with suspected CAD, patients with diabetes, and in survivors of cardiac arrests. This established that CMR imaging provided unique prediction of adverse cardiac events incremental to clinical tools and offered guidance to clinicians to use CMR in the appropriate clinical settings. The publications resulting from this work remain relevant supporting the appropriate use of CMR in clinical management of cardiac patients and continue to be cited by other groups.
34
Discovery of Novel Treatment to Acute Myocardial Infarction: The Multicenter OMEGAREMODEL Randomized Controlled Clinical Trial (2008-2013)
Our trial supported the notion that suppression of systemic and myocardial inflammation using omega-3 fatty acids provides a safe and unique treatment promoting inflammatory resolution and myocardial healing after an acute myocardial infarction. These results were published in Circulation in Aug 2016. We further discovered that genetic polymorphism exists in the response to omega-3 fatty acids. These results may have implication in reducing the high burden of post-MI heart failure and personalized treatment using patients' genotypes and biomarker profiles. A patent has been filed by BWH using these results.
Novel CMR Method I collaborated with Michael Jerosch-Herold, Ph.D. in developing a novel
of Fibrosis andquantitative method of myocardial fibrosis using serial T1-mapping imaging. I
Determining its
then evaluated its clinical impact in a wide array of cardiac diseases in patients.
Clinical Impact
This effort had resulted in 13 peer-reviewed publications illustrating the clinical
(2008-present)
impact of T1 mapping method in the diagnosis of causes of cardiomyopathy and prognosticating patients' risks. This effort had also helped establish the
role of CMR imaging as a unique method of tissue characterization and in
testing the therapeutic effects of novel drug treatments before planning of
largescale outcome trials. Our efforts had led to establishment of a CMR core
laboratory at BWH. Clinical outcome studies by my team assessing the clinical
diagnostic and prognostic impact of T1 mapping had contributed to the now
widespread application of T1 mapping in clinical diagnosis and research by
CMR in a wide array of cardiac conditions. In addition, my work represents a
proof-of-concept foundation of myocardial tissue characterization by CMR and
it has inspired the development of several other T1-mapping methods by other
CMR centers.
Development of ACC/AHA Practice and Training Guidelines (2009-present)
I was a member the writing groups of 4 major ACC/AHA Task Force Panels. These established current appropriate-use criteria of advance CV imaging techniques, practice guidelines of stable ischemic heart disease or prevention of sudden cardiac deaths, and COCATS training criteria in cardiovascular imaging. These efforts established the role of CMR imaging as evidenced by current literature, incremental to conventional non-imaging-based risk stratifying methods. The COCATS training criteria set the metrics and goals that are required for imaging training in CMR. I am currently working on 3 other practice guidelines in imaging for various governing societies.
CMR Imaging Core
Laboratory Towards
an
Innovative
Platform for Rapid
Therapeutic
Discoveries
(2012-present)
With its high quantitative reproducibility, tomographic coverage, and tissue characterizing features, CMR is a remarkable surrogate marker that can expedite the pace of therapeutic discoveries. I established the BWH CMR imaging core laboratory (https://cmrcore.bwh.harvard.edu) and standardized all core lab procedures for the purposes of using CMR in testing novel treatments for cardiac disorders. The BWH CMR imaging core laboratory currently has supported 12 clinical trials and generated a total direct funding of $3.9 million
35
Creation and Expansion of a Global CMR Registry (2013-present)
sponsored by NIH or pharmaceutical industries, focuses on testing of novel therapies or management strategies.
Given the complexities of CMR imaging, evaluation the clinical impact of this technology requires a guideline-supported standardized data collection infrastructure. I created a web-based de-identified international collaborative group promoting multicenter outcome research of CMR and cardiac CT (https://cmrcoop.partners.org). Since 2013, I have been appointed and served as the Chair of the SCMR global registry committee (http://www.scmr.org) and continue to oversee all aspects of its growth and development. This international registry has currently more than 40 participating centers and collected more than 65,000 CMR studies. This registry will provide evidence of real-world impact that will shape the proper and cost-effective adaptation of this novel imaging technology in patient care. Between 2014-2019, I led the registry to secure funding and completed a multicenter study to examine the current prognostic implications and cost-effectiveness of stress CMR imaging of stable chest pain patients in the United States (SPINS study of the SCMR registry).
Report of Teaching and Education Innovations
Founding of NonInvasive Cardiovascular Imaging (NCVI) program and NIH T32 Training (2008-present)
As a founding member of the NCVI program under the leadership of Dr. Marcelo Di Carli, I have developed and provided advanced clinical imaging training of more than 60 fellows, many of whom have become successful imaging experts in leading institutions. In 2013 we secured funding of a NIH T32 training grant in cardiovascular imaging towards imaging training of future academically and research-focused cardiovascular investigators.
Report of Technological and Other Scientific Innovations
Genotype Guided
Treatment Using Omega-3 Fatty Acids in Improving Survival of Patients with Acute Myocardial Infarction
US Patent Application (Appl no.: 62582608, EFS ID: 30879814) Inventor: Raymond Y. Kwong In this patent application, my research team described the genotyping of RS1535 polymorphism as an effect modifier to cardiac remodeling response to oral omega-3 fatty acids treatment, with implications to patient mortality, in patients who suffered an acute myocardial infarction.
36
Report of Education of Patients and Service to the Community
Educational Material for Patients and the Lay Community No materials below were sponsored by outside entities.
1. Kwong RY, Yucel EK. Cardiology patient pages. Computed tomography scan and magnetic resonance imaging. Circulation. 2003;108(15): e104-6. This article serves as an introductory level educational material for patients and primary care physicians at the time when advanced cardiac imaging techniques like cardiac MRI and CT were being introduced into patient care.
Recognition
Selected examples of related media coverage:
Study published as Research Investigation 100, Heydari B et al. Circulation 2016
American Heart Karen Astle. Omega-3 fatty acids
2016
Omega-3 fatty acids from fish oil, may Association Rapid from fish oil, may aid healing after
aid healing after heart attack
Access Journal heart attack. August 01, 2016. Report
https://newsroom.heart.org/
2016 High Doses of Fish Oil Might Help Healing After Heart Attack
U.S. News & World Report
James Bernstein. High Doses of Fish Oil Might Help Healing After Heart Attack. August 02, 2016 http://health.usnews.com/
2016 2016
Omega-3 Fatty Acids May Aid Heart Attack Healing
High Doses of Fish Oil Might Help Healing After Heart Attack
Reuters Health Kathryn Doyle. Omega-3 Fatty
Information
Acids May Aid Heart Attack
Healing. August 02, 2016
Thomson Reuters http://www.reuters.com/ -
UK
Http://uk.reuters.com/
Drugs.com
https://www.drugs.com/news/doses
-fish-oil-mighthelp-healing-
afterheart-attack-62170.html/
2016
CBS Boston Mallika Marshall, MD. Omega-3
Omega-3 Fatty Acids May Help Heart Channel 4 WBZ Fatty Acids May Help Heart Attack
Attack Survivors Heal
Survivors Heal. TV Interview.
http://boston.cbslocal.com/
2016 Fish Oil Has Benefits After a Heart Attack
Time
37
Alice Park. Fish Oil Has Benefits After a Heart Attack. August 02, 2016 http://www.time.com/
2018
The Clinical Impact of Stress CMR Perfusion Imaging in the United States
Report of Scholarship
(SPINS): A SCMR Registry Study. Talley Lauren Schoener-Gaynor.
Stress
Management CMR Impacts Patient Care in the
Group on Behalf US. of the Society for
Cardiovascular
Magnetic
Resonance
Peer reviewed publications in print or other media
Research Investigations
1. Freeman HJ, Kwong RY, Sacks SL. Granulomatous vaginal ulceration due to metastatic cutaneous Crohn's disease. Can J Gastroenterol. 1995;9(4):183-86.
2. Kwong RY, Carere RG, Thompson CR, Lichtenstein S. Ventricular rupture during coronary angioplasty for acute reinfarction. Cathet Cardiovasc Diagn. 1998;43(2):190-4.
3. Kwong RY, Schussheim AE, Rekhraj S, Aletras AH, Geller N, Davis J, Christian TF, Balaban RS, Arai AE. Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging. Circulation. 2003;107(4):531-7.
4. Tatli S, O'Gara PT, Lambert J, Kwong RY, Byrne JG, Yucel EK. MRI of atypical lipomatous hypertrophy of the interatrial septum. Am J Roentgenol. 2004;182(3):598-600.
5. Tatli S, Zou KH, Fruitman M, Reynolds HG, Foo T, Kwong R, Yucel EK. Three-dimensional magnetic resonance imaging technique for myocardial-delayed hyperenhancement: a comparison with the two-dimensional technique. J Magn Reson Imaging. 2004;20(3):378-82.
6. Ingkanisorn WP, Kwong RY, Bohme NS, Geller NL, Rhoads KL, Dyke CK, Paterson DI, Syed MA, Aletras AH, Arai AE. Prognosis of negative adenosine stress magnetic resonance in patients presenting to an emergency department with chest pain. J Am Coll Cardiol. 2006;47(7):1427-32.
7. Kwong RY, Chan AK, Brown KA, Chan CW, Reynolds HG, Tsang S, Davis RB. Impact of Unrecognized Myocardial Scar Detected by Cardiac Magnetic Resonance Imaging on EventFree Survival in Patients Presenting With Signs or Symptoms of Coronary Artery Disease. Circulation. 2006;113(23):2733-2743.
8. Yan AT, Shayne AJ, Brown KA, Gupta SN, Chan CWS, Luu TM, Di Carli MF, Reynolds HG, Stevenson WG, Kwong RY. Characterization of the Peri-Infarct Zone By Contrast-Enhanced Cardiac Magnetic Resonance Imaging Is a Powerful Predictor of Post-Myocardial Infarction Mortality. Circulation. 2006;114(1):32-39.
9. Yan AT, Gibson CM, Larose E, Anavekar NS, Tsang S, Solomon SD, Reynolds HG, Kwong RY. Characterization of Microvascular Dysfunction After Acute Myocardial Infarction by Cardiac Magnetic Resonance First-pass Perfusion and Late Gadolinium Enhancement Imaging. J Cardiovasc Magn Reson. 2006;8(6):831-837.
10. Larose E, Ganz P, Reynolds HG, Dorbala S, Di Carli MF, Brown KA, Kwong RY. Right Ventricular Dysfunction Assessed by Cardiovascular Magnetic Resonance Imaging Predicts Poor Prognosis Late After Myocardial Infarction. J Am Coll Cardiol. 2007;49(8):855-862.
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11. Dorbala S, Vangala D Sampson U, Limaye A, Kwong RY, Di Carli MF. Value of vasodilator left ventricular ejection fraction reserve in evaluating the magnitude of myocardium at risk and the extent of angiographic coronary artery disease: a 82Rb PET/CT study. J Nucl Med. 2007;48(3):349-58.
12. Sampson UK, Dorbala S, Limaye A, Kwong RY, Di Carli MF. Diagnostic Accuracy of Rubidium-82 Myocardial Perfusion Imaging With Hybrid Positron Emission Tomography/Computed Tomography (PET-CT) in the Detection of Coronary Artery Disease. J Am Coll Cardiol. 2007;49(10):1052-8.
13. Anavekar NS, Gerson D, Skali H, Kwong RY, Yucel EK, Solomon SD. Two-Dimensional Assessment of Right Ventricular Function: An Echocardiographic-MRI Correlative Study. Echocardiography. 2007;24(5):452-56.
14. Joffe HV, Kwong RY, Gerhard-Herman MD, Rice K, Feldman K, Adler GK. Beneficial Effects of Eplerenone Versus Hydrochlorothiazide on Coronary Circulatory Function in Patients with Diabetes Mellitus. J Clin Endocrinol Metab. 2007;92(7):2552-8.
15. Di Carli MF, Dorbala S, Curillova Z, Kwong RY, Goldhaber SZ, Rybicki FJ, Hachamovitch R. Relationship Between CT Coronary Angiography and Stress Perfusion Imaging in Patients with Suspected Ischemic Heart Disease Assessed by Integrated PET-CT Imaging. J Nucl Cardiol. 2007;14:799-809.
16. Tse HF, Thambar S, Kwong YL, Rowlings P, Bellamy G, McCrohon J, Thomas P, Bastian B, Chan JKF, Lo G, Ho CL, Chan WS, Kwong RY, Parker JA, Hauser TH, Chan J, Fong DYT, Lau CP. Prospective Randomized Trial of Direct Endomyocardial Implantation of Bone Marrow Cells for Therapeutic Angiogenesis in Severe Coronary Artery Diseases (PROTECTCAD Trial). Eur Heart J. 2007;28(24):2998-3005.
17. Schenker M. Dorbala S, Rybicki FJ, Kwong RY, Di Carli MF. Interrelation of coronary calcification, myocardial ischemia, and outcomes in patients with intermediate likelihood of coronary artery disease: a combined positron emission tomography/computed tomography study. Circulation. 2008;117(13): 1693-700.
18. Folkesson J, Samset E, Kwong RY, Westin CF. Unifying statistical classification and geodesic active regions for segmentation of cardiac MRI. IEEE Trans Inf Technol Biomed. 2008; 12(3):328-34.
19. Kwong RY, Sattar H, Wu H, Vorobiof G, Gandla V, Steel K, Siu S, Brown KA. Incidence and prognostic implication of unrecognized myocardial scar characterized by cardiac magnetic resonance in diabetic patients without clinical evidence of myocardial infarction. Circulation. 2008;118(10):1011-20.
20. Curillova Z, Yaman BF, Dorbala S, Kwong RY, Sitek A, El Fakhri G, Anagnostopoulos C, Di Carli MF. Quantitative relationship between coronary calcium content and coronary flow reserve as assessed by integrated PET/CT imaging. Eur J Nucl Med Mol Imaging. 2009;36(10):1603-10.
21. Schofer J, Siminiak T, Haude M, Herrman JP, Vainer J, Wu JC, Levy W, Mauri L, Feldman T, Kwong RY, Kaye D, Duffy S, Tübler T, Degen H, Brandt M, Van Bibber R, Goldberg S, Reuter DG, Hoppe U. Percutaneous Mitral Annuloplasty for Functional Mitral Regurgitation: Results of the AMADEUS Trial. Circulation. 2009; 120(4): 326-33.
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22. Dorbala S, Hachamovitch R, Curillova Z, Thomas D, Vangala D, Kwong RY, Di Carli MF. Incremental prognostic value of gated Rb-82 positron emission tomography myocardial perfusion imaging over clinical variables and rest LVEF. JACC Cardiovasc Imaging. 2009;2(7):846-54.
23. Steel K, Broderick R, Gandla V, Larose E, Resnic F, Jerosch-Herold M, Brown KA, Kwong RY. Complementary Prognostic Values of Stress Myocardial Perfusion and Late Gadolinium Enhancement Imaging by Cardiac Magnetic Resonance in Patients with Known or Suspected Coronary Artery Disease. Circulation. 2009; 120(14): 1390-1400.
24. Chan WSC, Kwong YL, Kwong RY, Lau CP, Tse HF. Improvement of myocardial perfusion reserve detected by cardiovascular magnetic resonance after direct endomyocardial implantation of autologous bone marrow cells in patients with severe coronary artery diseases. J Cardiovasc Magn Reson. 2010;12:6.
25. Lee LS, Ghanta RK, Mokashi SA, Coelho-Filho O, Kwong RY, Bolman RM, Chen FY. Ventricular restraint therapy for heart failure: the right ventricle is different from the left ventricle. J Thorac Cardiovasc Surg. 2010;139(4):1012-8.
26. Ho CY, López B, Coelho-Filho OR, Lakdawala NK, Cirino AL, Jarolim P, Kwong RY, González A, Colan SD, Seidman JG, Díez J, Seidman CE. Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy. N Engl J Med. 2010;363(6):552-63.
27. Schmitto JD, Mokashi SA, Lee LS, Laurence R, Schotola H, Coelho-Filho O, Rajab TK, Kwong RY, Bolman RM, Quintel M, Cohn LH, Chen FY. A novel, innovative ovine model of chronic ischemic cardiomyopathy induced by multiple coronary ligations. Artif Organs. 2010;34(11):918-22.
28. Coelho-Filho OR, Seabra L, Mongeon FP, Abdullah S, Francis S, Blankstein R, Di Carli M, Jerosch-Herold M, Kwong RY. Stress Myocardial Perfusion Imaging by Cardiac Magnetic Resonance Provides Strong Prognostic Value to Cardiac Events Regardless of Patient's Sex. JACC Cardiovasc Imaging. 2011;4(8): 850-861.
29. Farzaneh-Far A, Ariyarajah V, Shenoy C, Dorval J, Curillova Z, Wu H, Brown KB, Kwong RY. Left Atrial Passive Emptying Function During Dobutamine Magnetic Resonance Stress Imagingis a Predictor of Cardiac Events in Patients with Suspected Myocardial Ischemia. JACC Cardiovasc Imaging. 2011;4(4):378-88.
30. Armand P, Kim HT, Rhodes J, Sainvil MM, Cutler C, Ho VT, Koreth J, Alyea EP, Hearsey D, Neufeld EJ, Fleming MD, Steen H, Anderson D, Kwong RY, Soiffer RJ, Antin JH. Iron Overload in Patients with Acute Leukemia or MDS Undergoing Myeloablative Stem Cell Transplantation. Biol Blood Marrow Transplant. 2011;17(6):852-60.
31. Kaminski M, Steel K, Jerosch-Herold M, Khin M, Tsang S, Hauser T, Kwong RY. Strong cardiovascular prognostic implication of quantitative left atrial contractile function assessed by cardiac magnetic resonance imaging in patients with chronic hypertension. J Cardiovasc Magn Reson. 2011;13:42.
32. Lakdawala NK, Thune JJ, Maron BJ, Cirino AL, Havndrup O, Bundgaard H, Christiansen M, Carlsen CM, Dorval JF, Kwong RY, Colan SD, Køber LV, Ho CY. Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathy. Am J Cardiol. 2011;108(11):1606-13.
40
33. Armand P, Sainvil M, Kim HT, Rhodes J, Cutler C, Ho VT, Koreth J, Alyea EP, Neufeld EJ, Kwong RY, Soiffer RJ, Antin JH. Does iron overload really matter in stem cell transplantation? Am J Hematol. 2012;87(6):569-72.
34. Gottumukkala R, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA. Myocardial infarction triggers chronic cardiac autoimmunity in Type 1 diabetes. Sci Transl Med. 2012; 4(138):138ra80.
35. Mongeon FP, Jerosch-Herold M, Coelho-Filho OR, Blankstein R, Falk RH, Kwong RY. Quantification of Extracellular Matrix Expansion by CMR in Infiltrative Heart Disease. JACC Cardiovasc Imaging. 2012;5(9):897-907.
36. Lee LS, Ghanta RK, Mokashi SA, Coelho-Filho O, Kwong RY, Kwon M, Guan J, Liao R, Chen FY. Optimized ventricular restraint therapy: Adjustable restraint is superior to standard restraint in an ovine model of ischemic cardiomyopathy. J Thorac Cardiovasc Surg. 2013;145(3):824-31.
37. Armand P, Sainvil MM, Kim HT, Rhodes J, Cutler C, Ho VT, Koreth J, Alyea EP, Neufeld EJ, Kwong RY, Soiffer RJ, Antin JH. Pre-transplantation iron chelation in patients with MDS or acute leukemia and iron overload undergoing myeloablative allo-SCT. Bone Marrow Transplant. 2013;48(1):146-7.
38. Neilan TG, Coelho-Filho OR, Pena-Herrera D, Shah RV, Jerosch-Herold M, Francis SA, Moslehi J, Kwong RY. Left Ventricular Mass in Patients with a Cardiomyopathy after Treatment with Anthracyclines. Am J Cardiol. 2012;110(11):1679-86. PubMed PMID: 22917553; PubMed Central PMCID: PMC3496816.
39. Neilan TG, Coelho-Filho OR, Shah RV, Feng JH, Pena-Herrera D, Mandry D, Pierre-Mongeon F, Heydari B, Francis SA, Moslehi J, Kwong RY, Jerosch-Herold M. Myocardial Extracellular Volume by Cardiac Magnetic Resonance Imaging in Patients Treated With AnthracyclineBased Chemotherapy. Am J Cardiol. 2013;111(5):717-22.PubMed PMID: 23228924.
40. Coelho-Filho OR, Mongeon FP, Mitchell R, Moreno H Jr, Nadruz W Jr, Kwong RY, JeroschHerold M. Role of transcytolemmal water-exchange in magnetic resonance measurements of diffuse myocardial fibrosis in hypertensive heart disease. Circ Cardiovasc Imaging. 2013;6(1):134-41. PubMed PMID: 23159497.
41. Sharma B, Neilan TG, Kwong RY, Mandry D, Owens R, McSharry D, Bakker J, Malhotra A. Evaluation of right ventricular remodeling using cardiac magnetic resonance imaging in coexistent chronic obstructive pulmonary disease and obstructive sleep apnea. COPD. 2013 Feb;10(1):4-10. PubMed PMID:23272670
42. Welt FG, Gallegos R, Connell J, Kajstura J, D'Amario D, Kwong RY, Coelho-Filho O, Shah R, Mitchell R, Leri A, Foley L, Anversa P, Pfeffer MA. Effect of cardiac stem cells on leftventricular remodeling in a canine model of chronic myocardial infarction. Circ Heart Fail. 2013;6(1):99-106. PubMed PMID: 23212553.
43. Rao AD, Shah RV, Garg R, Abbasi SA, Neilan TG, Perlstein TS, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Relation of Aldosterone and Myocardial Extracellular Matrix Expansion in Patients with Type 2 Diabetes Mellitus. Am J Cardiol. 2013;112(1):73-8.
44. Shah RV, Abbasi SA, Heydari B, Rickers C, Jacobs DR Jr, Wang L, Kwong RY, Bluemke DA, Lima JA, Jerosch-Herold M. Insulin Resistance, Subclinical Left Ventricular Remodeling, and
41
the Obesity Paradox: The Multi-Ethnic Study of Atherosclerosis. J Am Coll Cardiol. 2013;61(16):1698-706. 45. Ho C, Abbasi SA, Neilan TG, Shah RV, Chen YC, Heydari B, Cirino AL, Lakdawala NK, Orav EJ, Gonzalez A, Lopez B, Diez J, Jerosch-Herold M, Kwong RY. T1 Measurements Identify Extracellular Volume Expansion in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy. Circulation Cardiovasc Imaging. 2013;6(3):415-22. 46. Neilan TG, Coelho-Filho OR, Shah RV, Abbasi SA, Heydari B, Watanabe E, Chen YC, Mandry D, Mongeon FP, Blankstein R, Kwong RY, Jerosch-Herold M. Myocardial extracellular volume fraction from T1 measurements in healthy volunteers and mice: relationship to aging and cardiac dimensions. JACC Cardiovasc Imaging. 2013;6(6):672-83. PMID: 23643283 47. Neilan TG, Coelho-Filho OR, Danik SB, Daly CA, Shah RV, Dodson JA, Verdini DJ, Tokuda M, Tedrow UB, Stevenson WG, Jerosch-Herold M, Ghoshhajra BB, Kwong RY. Late gadolinium enhancement and risk stratification in patients with a non-ischemic dilated cardiomyopathy undergoing insertion of an implantable cardioverter defibrillator. JACC Cardiovasc Imaging. 2013;6(9):944-54. 48. Schmidt EJ, Tse ZT, Reichlin TR, Michaud GF, Watkins RD, Butts-Pauly K, Kwong RY, Stevenson W, Schweitzer J, Byrd I, Dumoulin CL. Voltage-based device tracking in a 1.5 tesla MRI during imaging: initial validation in swine models. Magn Reson Med. 2013 Apr 11. Doi: 10.1002/mrm.24742. PMID: 23580479 49. Shah RV, Heydari B, Coelho-Filho O, Murthy V, Abbasi S, Feng JH, Pencina MJ, Neilan TG, Meadows JL, Francis S, Blankstein R, Steigner M, Di Carli MF, Jerosch-Herold M, Kwong RY. Stress Cardiac Magnetic Resonance Imaging Provides Effective Cardiac Risk Reclassification in Patients with Known or Suspected Stable Coronary Artery Disease. Circulation. 2013;128(6):605-14. PMID:23804252 50. Neilan TG, Shah RV, Abbasi SA, Farhad H, Groarke JD, Dodson JA, Coelho-Filho O, McMullan CJ, Heydari B, Michaud GF, John RM, van der Geest R, Steigner ML, Blankstein R, Jerosch-Herold M, Kwong RY. The Incidence, Pattern, and Prognostic value of Left Ventricular Myocardial Scar by Late Gadolinium Enhancement in Patients with Atrial Fibrillation. J Am Coll Cardiol. 2013;62(23):2205-14 . Neilan TG, Kwong RY. Reply: prognostic value of myocardial scar in atrial fibrillation. J Am Coll Cardiol. 2014 May 20;63(19):2055. doi: 10.1016/j.jacc.2014.01.027. Epub 2014 Feb 19. No abstract available. PMID: 24561138 51. Shah RV, Abbasi SA, Neilan TG, Hulten E, Coelho-Filho O, Hoppin A, Levitsky L, de Ferranti S, Rhodes ET, Traum A, Goodman E, Feng H, Heydari B, Harris WS, Hoefner DM, McConnell JP, Seethamraju R, Rickers C, Kwong RY, Jerosch-Herold M. Myocardial tissue remodeling in adolescent obesity. J Am Heart Assoc. 2013 Aug 20;2(4):e000279. 52. Coelho-Filho OR, Shah RV, Mitchell R, Neilan TG, Moreno H Jr, Simonson B, Kwong RY, Rosenzweig A, Das S, Jerosch-Herold M. Quantification of cardiomyocyte hypertrophy by cardiac magnetic resonance: implications for early cardiac remodeling. Circulation. 2013;128(11):1225-33. Doi: 10.1161/ PMID: 23912910
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53. Phillips LM, Hachamovitch R, Berman DS, Iskandrian AE, Min JK, Picard MH, Kwong RY, Friedrich MG, Scherrer-Crosbie M, Hayes SW, Sharir T, Gosselin G, Mazzanti M, Senior R, Beanlands R, Smanio P, Goyal A, Al-Mallah M, Reynolds H, Stone GW, Maron DJ, Shaw LJ. Lessons learned from MPI and physiologic testing in randomized trials of stable ischemic heart disease: COURAGE, BARI 2D, FAME, and ISCHEMIA. J Nucl Cardiol. 2013;20(6):969-75.
54. Hsiao E, Ali B, Blankstein R, Skali H, Ali T, Bruyere J Jr, Kwong RY, Di Carli MF, Dorbala S. Detection of Obstructive Coronary Artery Disease Using Regadenoson Stress and 82Rb PET/CT Myocardial Perfusion Imaging. J Nucl Med. 2013;54(10):1748-54.
55. Neilan TG, Coelho-Filho OR, Danik SB, Shah RV, Dodson JA, Verdini DJ, Tokuda M, Daly CA, Tedrow UB, Stevenson WG, Jerosch-Herold M, Ghoshhajra BB, Kwong RY. CMR Quantification of Myocardial Scar Provides Additive Prognostic Information in Nonischemic Cardiomyopathy. JACC Cardiovasc Imaging. 2013;6(9):944-54.
56. Neilan TG, Farhad H, Dodson JA, Shah RV, Abbasi SA, Bakker JP, Michaud GF, van der Geest R, Blankstein R, Steigner M, John RM, Jerosch-Herold M, Malhotra A, Kwong RY. Effect of sleep apnea and continuous positive airway pressure on cardiac structure and recurrence of atrial fibrillation. J Am Heart Assoc. 2013;2(6):e000421. Doi: 10.1161/JAHA.113.000421. PubMed PMID: 24275628.
57. Tse ZT, Dumoulin CL, Clifford GD, Schweitzer J, Qin L, Oster J, Jerosch-Herold M, Kwong RY, Michaud G, Stevenson WG, Schmidt EJ. A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention. Magn Reson Med. 2014;71(3):1336-47.
58. Abbasi SA, Ertel A, Shah RV, Dandekar V, Chung J, Bhat G, Desai AA, Kwong RY, Farzaneh-Far A. Impact of Cardiovascular Magnetic Resonance on Management and Clinical Decision-Making in Heart Failure Patients. J Cardiovasc Magn Reson. 2013;15(1):89. PMID: 24083836. Erratum in: J Cardiovasc Magn Reson. 2014;16:20 [reversed legends for Figures 2 and 3].
59. Shaw LJ, Berman DS, Picard MH, Friedrich MG, Kwong RY, Stone GW, Senior R, Min JK, Hachamovitch R, Scherrer-Crosbie M, Mieres JH, Marwick TH, Phillips LM, Chaudhry FA, Pellikka PA, Slomka P, Arai AE, Iskandrian AE, Bateman TM, Heller GV, Miller TD, Nagel E, Goyal A, Borges-Neto S, Boden WE, Reynolds HR, Hochman JS, Maron DJ, Douglas PS National Institutes of Health/National Heart, Lung, and Blood Institute-Sponsored ISCHEMIA Trial Investigators. Comparative Definitions for Moderate-Severe Ischemia in Stress Nuclear, Echocardiography, and Magnetic Resonance Imaging. 2014;7(6):593-604. Erratum in: JACC Cardiovasc Imaging. 2014;7(7):748 [revised text in Figure 4].
60. Blankstein R, Osborne M, Naya M, Waller A, Kim CK, Murthy VL, Kazemian P, Kwong RY, Tokuda M, Skali H, Padera R, Hainer J, Stevenson WG, Dorbala S, Di Carli MF. Cardiac Positron Emission Tomography Enhances Prognostic Assessments of Patients with Suspected Cardiac Sarcoidosis. J Am Coll Cardiol. 2014;63(4):329-36. .
61. Neilan TG, Mongeon FP, Shah RV, Coelho-Filho O, Abbasi SA, Dodson JA, McMullan CJ, Heydari B, Michaud GF, John RM, Blankstein R, Jerosch-Herold M, Kwong RY. Myocardial Extracellular Volume Expansion and the Risk of Recurrent Atrial Fibrillation After Pulmonary Vein Isolation. JACC Cardiovasc Imaging. 2014;7(1):1-11. PMID: 24290570
62. Shah RV, Heydari B, Coelho-Filho O, Abbasi S, Feng JH, Neilan TG, Francis S, Blankstein R, Steigner M; Jerosch-Herold M, Kwong RY. Vasodilator Stress Perfusion Cardiac Magnetic
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Resonance Imaging is Feasible and Prognostic in Obese Patients. JACC Cardiovasc Imaging. 2014;7(5):462-72. PMID: 24726254 63. Shah RV, Abbasi SA, Heydari B, Farhad H, Dodson JA, Bakker JP, John RM, Veves A, Malhotra A, Blankstein R, Jerosch-Herold M, Kwong RY, Neilan TG. Obesity and sleep apnea are independently associated with adverse left ventricular remodeling and clinical outcome in patients with atrial fibrillation and preserved ventricular function. Am Heart J. 2014;167(4):620-6.
64. Cevasco M, Kwon M, Fiedler A, Lee LS, Shiao J, Shah RV, Worthington AH, Fox JA, Kwong RY, Chen FY. Right Heart Failure: An Ischemic Model and Restraint Therapy for Treatment. Ann Thorac Surg. 2014;97(4):1356-62; discussion 1362-3. PubMed PMID: 24462414.
65. Watanabe E, Abbasi SA, Heydari B, Coelho-Filho OR, Shah R, Neilan TG, Murthy VL, Mongeon FP, Barbhaiya C, Jerosch-Herold M, Blankstein R, Hatabu H, van der Geest RJ, Stevenson WG, Kwong RY. Infarct Tissue Heterogeneity by Contrast-Enhanced Magnetic Resonance Imaging Is A Novel Predictor of Mortality in Patients with Chronic Coronary Artery Disease and Left Ventricular Dysfunction. Circ Cardiovasc Imaging. 2014;7(6):887-894.
66. Gregory TS, Schmidt EJ, Zhang SH, Kwong RY, Stevenson WG, Murrow JR, Tse ZT. LeftVentricular Mechanical Activation and Aortic-Arch Orientation Recovered from MagnetoHydrodynamic Voltages Observed in 12-Lead ECGs Obtained Inside MRIs: A Feasibility Study. Ann Biomed Eng. 2014;42(12):2480-9.
67. Abbasi SA, Heydari B, Shah RV, Murthy VL, Zhang YY, Blankstein R, Steigner M, JeroschHerold M, Kwong RY. Risk stratification by regadenoson stress magnetic resonance imaging in patients with known or suspected coronary artery disease. Am J Cardiol. 2014;114(8):1198203.
68. Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P. Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata. Circ Cardiovasc Imaging. 2014;7(6):920-9.
69. Liu H, Juan YH, Wang Q, Xie Z, Chen J, Huang H, Zhang X, Yang L, Liang C, Chung T, Kwong RY, Saboo SS. Evaluation of malposition of the branch pulmonary arteries using cardiovascular computed tomography angiography. Eur Radiol. 2014;24(12):3300-7.
70. Coelho-Filho OR, Shah RV, Neilan TG, Mitchell R, Moreno H Jr, Kwong R, Jerosch-Herold M. Cardiac magnetic resonance assessment of interstitial myocardial fibrosis and cardiomyocyte hypertrophy in hypertensive mice treated with spironolactone. J Am Heart Assoc. 2014;3(3):e000790.
71. Groarke JD, Waller AH, Vita TS, Michaud GF, Di Carli MF, Blankstein R, Kwong RY, Steigner M. Feasibility study of electrocardiographic and respiratory gated, gadolinium enhanced magnetic resonance angiography of pulmonary veins and the impact of heart rate and rhythm on study quality. J Cardiovasc Magn Reson. 2014;16:43.
72. Dodson JA, Neilan TG, Shah RV, Farhad H, Blankstein R, Steigner M, Michaud GF, John R, Abbasi SA, Jerosch-Herold M, Kwong RY. Left atrial passive emptying function determined by cardiac magnetic resonance predicts atrial fibrillation recurrence after pulmonary vein isolation. Circ Cardiovasc Imaging. 2014;7(4):586-92. PMID: 24902586
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73. Bittencourt MS, Christman MP, Hulten E, Divakaran S, Skali H, Kwong RY, Hainer J, Forman DE, Kirshenbaum JM, Dorbala S, Di Carli MF, Blankstein R. Comparison of the use of downstream tests after exercise treadmill testing by cardiologists versus noncardiologists. Am J Cardiol. 2014;114(2):305-11.
74. Christman MP, Bittencourt MS, Hulten E, Saksena E, Hainer J, Skali H, Kwong RY, Forman DE, Dorbala S, O'Gara PT, Di Carli MF, Blankstein R. Yield of downstream tests after exercise treadmill testing: a prospective cohort study. J Am Coll Cardiol. 2014 Apr 8;63(13):1264-74. Doi: 10.1016/j.jacc.2013.11.052. Epub 2014 Feb 5. PMID: 24509269
75. Shah RV, Murthy VL, Abbasi SA, Blankstein R, Kwong RY, Goldfine AB, Jerosch-Herold M, Lima JA, Ding J, Allison MA. Visceral adiposity and the risk of metabolic syndrome across body mass index: the MESA Study. JACC Cardiovasc Imaging. 2014;7(12):1221-35.
76. Neilan TG, Bakker JP, Sharma B, Owens RL, Farhad H, Shah RV, Abbasi SA, Kohli P, Wilson J, DeMaria A, Jerosch-Herold M, Kwong RY, Malhotra A. T1 measurements for detection of expansion of the myocardial extracellular volume in chronic obstructive pulmonary disease. Can J Cardiol. 2014;30(12):1668-75.
77. Ho CY, Lakdawala NK, Cirino AL, Lipshultz SE, Sparks E, Abbasi SA, Kwong RY, Antman EM, Semsarian C, González A, López B, Diez J, Orav EJ, Colan SD, Seidman CE. Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression. JACC Heart Fail. 2015;3(2):180-8.
78. Garg R, Rao AD, Baimas-George M, Hurwitz S, Foster C, Shah RV, Jerosch-Herold M, Kwong RY, Di Carli MF, Adler GK. Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals with Type 2 Diabetes Mellitus. Diabetes. 2015;64(1):236-42.
79. Shah RV, Murthy VL, Abbasi SA, Eng J, Wu C, Ouyang P, Kwong RY, Goldfine A, Bluemke DA, Lima J, Jerosch-Herold M. Weight loss and progressive left ventricular remodeling: The Multi-Ethnic Study of Atherosclerosis (MESA). Eur J Prev Cardiol. 2015;22(11):1408-18.
80. Neilan TG, Farhad H, Mayrhofer T, Shah RV, Dodson JA, Abbasi SA, Danik SB, Verdini DJ, Tokuda M, Tedrow UB, Jerosch-Herold M, Hoffmann U, Ghoshhajra BB, Stevenson WG, Kwong RY. Late Gadolinium Enhancement Among Survivors of sudden cardiac arrest. JACC Cardiovasc Imaging. 2015;8(4):414-23. PMID: 25797123
81. Liu H, Juan YH, Chen J, Xie Z, Wang Q, Zhang X, Liang C, Huang H, Kwong RY, Saboo SS. Anomalous Origin of One Pulmonary Artery Branch From the Aorta: Role of MDCT Angiography. AJR Am J Roentgenol. 2015;204(5):979-87.
82. Kwong RY, Heydari B, Abbasi S, Steel K, Al-Mallah M, Wu H, Falk R. Characterization of Cardiac Amyloidosis by Atrial Late Gadolinium Enhancement Using Contrast Enhanced Cardiac Magnetic Resonance Imaging and Correlation with Left Atrial Conduit and Contractile Function. Am J Cardiol. 2015;116(4):622-9. PMID: 26076990
83. Suinesiaputra A, Bluemke DA, Cowan BR, Friedrich MG, Kramer CM, Kwong R, Plein S, Schulz-Menger J, Westenberg JJ, Young AA, Nagel E. Quantification of LV function and mass by cardiovascular magnetic resonance: multi-center variability and consensus contours. J Cardiovasc Magn Reson. 2015;17(1):63.
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84. Kramer CM, Appelbaum E, Desai MY, Desvigne-Nickens P, DiMarco JP, Friedrich MG, Geller N4, Heckler S, Ho CY, Jerosch-Herold M, Ivey EA7, Keleti J, Kim DY, Kolm P, Kwong RY, Maron MS, Schulz-Menger J, Piechnik S, Watkins H, Weintraub WS, Wu P, Neubauer S. Hypertrophic Cardiomyopathy Registry: The rationale and design of an international, observational study of hypertrophic cardiomyopathy. Am Heart J. 2015;170(2):223-30.
85. Gregory TS, Oshinski J, Schmidt EJ, Kwong RY, Stevenson WG, Ho Tse ZT. Continuous Rapid Quantification of Stroke Volume Using Magnetohydrodynamic Voltages in 3T Magnetic Resonance Imaging. Circ Cardiovasc Imaging. 2015;8(12). pii: e003282.
86. Zhang SH, Tse ZT, Dumoulin CL, Kwong RY, Stevenson WG, Watkins R, Ward J, Wang W, Schmidt EJ. Gradient-induced voltages on 12-lead ECGs during high duty-cycle MRI sequences and a method for their removal considering linear and concomitant gradient terms. Magn Reson Med. 2016;75(5):2204-16.
87. Moschetti K, Petersen SE, Pilz G, Kwong RY, Wasserfallen JB, Lombardi M, Korosoglou G, Van Rossum AC, Bruder O, Mahrholdt H, Schwitter J. Cost-minimization analysis of three decision strategies for cardiac revascularization: results of the "suspected CAD" cohort of the european cardiovascular magnetic resonance registry. J Cardiovasc Magn Reson. 2016;18(1):3.
88. Heydari B, Juan YH, Liu H, Abbasi S, Shah RV, Blankstein R, Steigner M, Jerosch-Herold M, Kwong RY. Stress Perfusion Cardiovascular Magnetic Resonance Imaging Effectively Risk Stratifies Diabetic Patients With Suspected Myocardial Ischemia. Circ Cardiovasc Imaging. 2016;9(4):e004136.
89. Freedman JE, Gerstein M, Mick E, Rozowsky J, Levy D, Kitchen R, Das S, Shah R, Danielson K, Beaulieu L, Navarro FC, Wang Y, Galeev TR, Holman A, Kwong RY, Murthy V, Tanriverdi SE, Koupenova M, Mikhalev E, Tanriverdi K. Diverse human extracellular RNAs are widely detected in human plasma. Nat Commun. 2016;7:11106. Corrigendum in: Nat Commun. 2016;7:11902 [corrected name of author Koupenova M].
90. Heydari B, Abdullah SA, Pottala J, Shah RV, Abbasi SA, Mandry D, Francis SA, Lumish H, Ghoshhajra BB, Hoffmann U, Appelbaum E, Feng JH, Blankstein R, Steigner M, McConnell JP, Harris W, Antman EM, Jerosch-Herold M, Kwong RY. Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGAREMODEL Randomized Clinical Trial. Circulation. 2016;134(5):378-91. Author response to correspondence: Circulation. 2014 Apr 15;129(15):e451. Doi: 10.1161/CIRCULATIONAHA.114.008031. Results of this randomized controlled trial were articled in > 162 major news outlets (including Reuters Health, NPR, Times, WebMD) and viewed by > 151 million viewers in the first 4 months of publication. I was interviewed by CBS Boston Channel WBZ.
91. Hulten E, Agarwal V, Cahill M, Cole G, Vita T, Parrish S, Bittencourt MS, Murthy VL, Kwong RY, DiCarli MF, Blankstein R. Presence of Late Gadolinium Enhancement by Cardiac Magnetic Resonance Among Patients With Suspected Cardiac Sarcoidosis Is Associated With Adverse Cardiovascular Prognosis: A Systematic Review and Meta-Analysis. Circ Cardiovasc Imaging. 2016;9(9):e005001.
92. Hiremath P, Lawler PR, Ho JE, Correia AW, Abbasi SA, Kwong RY, Jerosch-Herold M, Ho CY, Cheng S. Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic
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Cardiomyopathy Carcomere Mutation Carriers With and Without Left Ventricular Hypertrophy. Circ Heart Fail. 2016;9(9) pii: e003026. 93. Addison D, Farhad H, Shah RV, Mayrhofer T, Abbasi SA, John RM, Michaud GF, JeroschHerold M, Hoffmann U, Stevenson WG, Kwong RY, Neilan TG. Effect of Late Gadolinium Enhancement on the Recovery of Left Ventricular Systolic Function After Pulmonary Vein Isolation. J Am Heart Assoc. 2016;5(9). pii: e003570. 94. Abbasi SA, Shah RV, McNulty SE, Hernandez AF, Semigran MJ, Lewis GD, Jerosch-Herold M, Kim RJ, Redfield MM, Kwong RY. Left Atrial Structure and Function in Heart Failure with Preserved Ejection Fraction: A RELAX Substudy. PLoS One. 2016;11(11):e0164914. PMID: 27812147 95. Kwong RY, Petersen SE, Schulz-Menger J, Arai AE, Bingham SE, Chen Y, Choi YL, Cury RC, Ferreira VM, Flamm SD, Steel K, Bandettini P, Martin ET, Nallamshetty L, Neubauer S, Raman S, Schelbert EB, Valeti US, Cao J, Reichek N, Young A, Fexon L, Pivovarov MS, Ferrari V, Simonetti OP. The Global Cardiovascular Magnetic Resonance Registry (GCMR) of the Society for Cardiovascular Magnetic Resonance (SCMR): Its Goals, Rationale, Data Infrastructure, and Current Developments. J Cardiovasc Magn Reson. 2017;19(1):23. PMID:28187739 96. Farhad H, Staziaki PV, Addison D, Coelho-Filho OR, Shah RV, Mitchell RN, Szilveszter B, Abbasi SA, Kwong RY, Scherrer-Crosbie M, Hoffmann U, Jerosch-Herold M, Neilan TG. Characterization of the Changes in Cardiac Structure and Function in Mice Treated with Anthracyclines Using Serial Cardiac Magnetic Resonance Imaging. Circ Cardiovasc Imaging. 2016;9(12). pii: e003584. 97. Bière L, Behaghel V, Mateus V, Assunção A Jr, Gräni C, Ouerghi K, Grall S, Willoteaux S, Prunier F, Kwong RY, Furber A. Relation of Quantity of Subepicardial Adipose Tissue to Infarct Size in Patients With ST-Elevation Myocardial Infarction. Am J Cardiol. 2017;119(12):1972-78. 98. Bayomy O, Rao AD, Garg R, Vaidya A, Kotin AR, Reiber B, Nijmeijer S, Di Carli MF, Jerosch-Herold M, Kwong RY, Adler GK. Plasminogen Activator Inhibitor-1 and Pericardial Fat in Individuals with Type 2 Diabetes Mellitus. Metab Syndr Relat Disord. 2017;15(6):26975. 99. Gräni C, Bière L, Murthy VL, Agarwal V, Kaneko K, Cuddy S, Aghayev A, Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Prognostic Value of Cardiac Magnetic Resonance Tissue Characterization in Risk Stratifying Patients with Suspected Myocarditis. J Am Coll Cardiol. 2017;70(16):1964-76. Erratum in: J Am Coll Cardiol. 2017;70(21):2736 [corrected formula on page 1967]. 100. Miskulin DC, Gassman J, Schrader R, Gul A, Jhamb M, Ploth DW, Negrea L, Kwong RY, Levey AS, Singh AK, Harford A, Paine S, Kendrick C, Rahman M Zager P. Blood Pressure in Dialysis: Results of a Pilot Study. J Am Soc Nephrol. 2018;29(1):307-316. 101. Chin MS, Steigner M, Yin W, Kwong RY, Siedlecki AM. Intraluminal Assessment of Coronary Arteries With Ferumoxytol-Enhanced Magnetic Resonance Angiography. JACC Cardiovasc Imaging. 2018;11(3):505-508. 102. Danielson KM, Shah R, Yeri A, Liu X, Camacho Garcia F, Silverman M, Tanriverdi K, Das A,
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Xiao C, Jerosch-Herold M, Heydari B, Abbasi S, Van Keuren-Jensen K, Freedman JE, Wang YE, Rosenzweig A, Kwong RY, Das S. Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction. EBioMedicine. 2018;32:172-81.
103. Vita T, Okada DR, Veillet-Chowdhury M, Bravo PE, Mullins E, Hulten E, Agrawal M, Madan R, Taqueti VR, Steigner M, Skali H, Kwong RY, Stewart GC, Dorbala S, Di Carli MF, Blankstein R. Complementary Value of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography/Computed Tomography in the Assessment of Cardiac Sarcoidosis. Circ Cardiovasc Imaging. 2018;11(1):e007030.
104. Shamir AR, Karembeikar A, Yabes J, Yao Y, Miskullin D, Gassman J, Ploth D, Negrea L, Rahman M, Kwong RY, Zager P, Jhamb M. Association of Intradialytic Hypertension with Left Ventricular Mass in Hypertensive Hemodialysis Patients Enrolled in the Blood Pressure in Dialysis (BID) Study. Kidney Blood Press Res. 2018;43(3):882-92.
105. Heydari B, Abdullah S, Shah R, Abbasi S, Francis S, Lumish H, Feng JH, McConnell J, Harris W, Antman EM, Jerosch-Herold M, Kwong RY. High-Dose Omega-3 Fatty Acids Attenuate Post-Myocardial Infarction ST2 Levels Relating to Heart Failure Outcomes and Myocardial Fibrosis. J Am Coll Cardiol. 2018;72(8):953-955
106. Puntmann VO, Valbuena S, Hinojar R, Petersen SE, Greenwood JP, Kramer CM, Kwong RY, McCann GP, Berry C, Nagel E. SCMR Clinical Trial Writing Group. Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification. J Cardiovasc Magn Reson. 2018 Sep 20;20(1):67
107. Bravo PE, Fujikura K, Kijewski MF, Jerosch-Herold M, Jacob S, El-Sady MS, Sticka W, Dubey S, Belanger A, Park MA, Di Carli MF, Kwong RY, Falk RH, Dorbala S. Relative Apical Sparing of Myocardial Longitudinal Strain Is Explained by Regional Differences in Total Amyloid Mass Rather Than the Proportion of Amyloid Deposits. JACC Cardiovasc Imaging. 2018 Aug 15. pii: S1936-878X(18)30546-1
108. Muthalaly RG*, Kwong RY*, John RM, van der Geest RJ, Tao Q, Schaeffer B, Tanigawa S, Nakamura T, Kaneko K, Tedrow UB, Stevenson WG, Epstein LM, Kapur S, Zei PC, Koplan BA. Left Ventricular Entropy is a Novel Predictor of Arrhythmic Events in Dilated Cardiomyopathy Patients Receiving a Primary Prevention Defibrillator. JACC Cardiovasc Imaging. 2018 Aug 9. pii: S1936-878X(18)30548-5. [Epub ahead of print]. *co-first authors.
109. Vita T, Gräni C, Abbasi S, Neilan T, Rowin E, Coelho-Filho O, Watanabe E, Mongeon FP, Farhad H, Rassi CH, Choi C, Cheng K, Givertz M, Blankstein R, Steigner M, Aghayev A, Jerosch-Herold M, Kwong RY. Comparing CMR Mapping Methods and Myocardial Patterns Towards Heart Failure Outcomes in Non-Ischemic Dilated Cardiomyopathy. JACC Cardiovasc Imaging. 2018 Nov 8. pii: S1936-878X(18)30749-6 (Epub ahead of print]
110. Indorkar R, Romano S, White BE, Salazar P, Chia RC, Trybula M, Evans K, Kwong RY, Farzaneh-Far A. Global Coronary Flow Reserve Measured during Stress Cardiac Magnetic Resonance Imaging is an Independent Predictor of Adverse Cardiovascular Events. JACC Cardiovasc Imaging 2018 Oct 22. pii: S1936-878X(18)30745-9. [Epub ahead of print]
111. Haas AV, Rosner BA, Kwong RY, Rao AD, Garg R, Di Carli MF, Adler GK. Sex Differences in Coronary Microvascular Function in Individuals with Type 2 Diabetes Mellitus. Diabetes. 2018 Nov 8. pii: db180650. doi: 10.2337/db18-0650. [Epub ahead of print]
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112. Mousavi N, Cheezum MK, Aghayev A, Padera R, Vita T, Steigner M, Hulten E, Bittencourt MS, Dorbala S, Di Carli MF, Kwong RY, Dunne R, Blankstein R. Assessment of Cardiac Masses by Cardiac Magnetic Resonance Imaging: Histological Correlation and Clinical Outcomes. J Am Heart Assoc. 2019 Jan 8;8(1):e007829. doi: 10.1161/JAHA.117.007829.
113. Gräni C, Eichhorn C, Bière L, Kyoichi Kaneko, Murthy VL, Agarwal V, Aghayev A, Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Comparison of Myocardial Fibrosis Quantification Methods by Cardiovascular Magnetic Resonance Imaging for Risk Stratification of Patients with Suspected Myocarditis. Journal of Cardiovascular Magnetic Resonance 2019 Feb 28;21(1):14. doi: 10.1186/s12968-019-0520-0
114. Gräni C, Bière L, Eichhorn C, Kaneko K, Agarwal V, Aghayev A, Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Incremental value of extracellular volume assessment by cardiovascular magnetic resonance imaging in risk stratifying patients with suspected myocarditis. Int J Cardiovasc Imaging. 2019 Feb 12. doi: 10.1007/s10554-019-01552-6. [Epub ahead of print]
115. Romano S, Romer B, Trybula M, Evans K, Shenoy C, Kwong RY, Farzaneh-Far A. Prognostic implications of blunted feature-tracking global longitudinal strain during vasodilator cardiovascular magnetic resonance stress imaging. JACC Cardiovasc Imaging 2019 Mar 15. pii: S1936-878X(19)30226-8. doi: 10.1016/j.jcmg.2019.03.002. [Epub ahead of print] PMID: 31005520
Other Peer-Reviewed Publications
1. Madore B, Hoge WS, Kwong R. Extension of the UNFOLD method to include free breathing. Magn Reson Med. 2006;55(2):352-62.
2. Ariyarajah V, Jassal DS, Kirkpatrick I, Kwong RY. The utility of cardiovascular magnetic resonance in constrictive pericardial disease. Cardiol Rev. 2009;17(2):77-82.
3. Partington SL, Seabra LF, Kwong RY. Cardiac magnetic resonance imaging as a prognostic tool in patients with nonischemic cardiomyopathy. Hosp Pract (Minneap). 2010;38(4):75-82.
4. Buckley O, Doyle L, Padera R, Lakdawala N, Dorbala S, Di Carli M, Kwong RY, Desai A, Blankstein R. Cardiomyopathy of uncertain etiology: Complementary role of multimodality imaging with cardiac MRI and 18FDG PET. J Nucl Cardiol. 2010; 17(2): 328-32.
5. Stillman AE, Oudkerk M, Bluemke D, Bremerich J, Esteves FP, Garcia EV, Gutberlet M, Hundley WG, Jerosch-Herold M, Kuijpers D, Kwong RY, Nagel E, Lerakis S, Oshinski J, Paul JF, Underwood R, Wintersperger BJ, Rees MR. Assessment of acute myocardial infarction: current status and recommendations from the North American society for cardiovascular imaging and the European society of cardiac radiology. Int J Cardiovasc Imaging. 2011;27(1):724.
6. Heydari B, Jerosch-Herold M, Kwong RY. Assessment of myocardial ischemia with cardiovascular magnetic resonance. Prog Cardiovasc Dis. 2011; 54(3):191-203.
7. Heydari B, Jerosch-Herold M, Kwong RY. Imaging for Planning of Cardiac Resynchronization Therapy. State-of-the-Art Paper. JACC Cardiovascular Imaging. 2012;5(1):93-110.
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8. Francis SA, Daly C, Heydari B, Abbasi S, Shah RV, Kwong RY. Cost-effectiveness analysis for imaging techniques with a focus on cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2013;15:52. PMID: 23767423
9. Friedrich MG, Bucciarelli-Ducci C, White JA, Plein S, Moon JC, Almeida AG, Kramer CM, Neubauer S, Pennell DJ, Petersen SE, Kwong RY, Ferrari VA, Schulz-Menger J, Sakuma H, Schelbert EB, Larose É, Eitel I, Carbone I, Taylor AJ, Young A, de Roos A, Nagel E., Simplifying cardiovascular magnetic resonance pulse sequence terminology. J Cardiovasc Magn Reson. 2014;16:3960. doi: 10.1186/s12968-014-0103-z.
10. Juan YH, Waller AH, Saboo SS, Lin YC, Liu H, Kwong RY, Steigner ML. Myocardial crypts: role of modified two-chamber view. QJM. 2015;108(2):139-40. PMID: 24811548
11. Fontana M, Treibel TA, Martinez-Naharro A, Rosmini S, Kwong RY, Gillmore JD, Hawkins PN, Moon JC. A case report in cardiovascular magnetic resonance: the contrast agent matters in amyloid. BMC Med Imaging. 2017 Jan 7;17(1):3. doi: 10.1186/s12880-016-0173-5.
12. Gräni C, Buechel RR, Kaufmann PA, Kwong RY. Multimodality Imaging in Individuals With Anomalous Coronary Arteries. JACC Cardiovasc Imaging. 2017;10(4):471-481.
13. Stillman AE, Oudkerk M, Bluemke D, Jan de Boer M, Bremerich J, Garcia EV, Gutberlet M, van der Harst P, Hundley G, Jerosch-Herold M, Kuijpers D, Kwong RY, Nagel E, Lerakis Stamatios, Oshinshi J, Paul JF, Slart R, Thourani V, Vliegenthart R, Wintersperger B. Imaging the Myocardial Ischemic Cascade. I J Cardiovasc Imaging. 2018;34(8):1249-63. Corrigendum in: Int J Cardiovasc Imaging. 2018 Jul 24. doi: 10.1007/s10554-018-1408-z. [Epub ahead of print] [corrected spelling of author Gutberlet M]
14. Muthalaly R, Herlekar N, Kwong RY, Nasis A. Magnetic Resonance Imaging in Patients with Cardiac Implantable Electronic Devices. Radiology. 2018 Nov;289(2):281-292. doi: 10.1148/radiol.2018180285. Epub 2018 Sep 25.
Non-peer reviewed scientific or medical publications/materials in print or other media Reviews, Chapters, Monographs, and Editorials
1.
Wasserman A, Kwong RY. Glycoprotein Iib/IIIa Inhibitors for Acute Coronary Syndrome.
Cardiology Review. 1998;15(11):61-62.
2.
Wasserman A, Kwong RY. Dofetilide- A New Class III Antiarrhythmic Agent. Cardiology
Review. 1999;12(2):44-45.
3.
Wasserman A, Kwong RY. New Thrombolytic Agents for Acute Myocardial Infarction.
Cardiology Review. 1999;15(2):55-65.
4.
Boxt LM, Lipton MJ, Kwong RY, Rybicki F, Clouse ME. Computed tomography for
assessment of cardiac chambers, valves, myocardium and pericardium. Cardiol Clin.
2003;21(4):561-85.
5.
Arai AE, Kwong RY. Detecting Acute Coronary Syndrome in the Emergency Department
with Cardiac Magnetic Resonance Imaging. Cardiovascular Reviews and Reports.
2004;25(4):149-154.
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6. Kwong RY, Arai AE. Detecting Patients with Acute Coronary Syndromes in the Chest Pain Center of the Emergency Department With Cardiac Magnetic Resonance Imaging. Crit Pathw Cardiol. 2004;3(1):25-31.
7. Kwong RY, Falk RH. Cardiovascular magnetic resonance in cardiac amyloidosis. Circulation. 2005;111(2):122-4.
8. Baim DS, Kwong RY. Is magnetic resonance image guidance the key to opening chronic total occlusions? Circulation. 2006;113(8):1053-5.
9. Kwong RY. Assessment of Myocardial Viability by Cardiac MRI. In: Di Carli MF, Lipton MJ, editors. Cardiac PET and PET/CT Imaging. Secaucus, NJ: Springer Science and Business Media, Inc.;2006. P. 283-94.
10. Khin MM, Kwong RY. Assessment of Cardiac and Pericardial Tumor by Cardiovascular Magnetic Resonance. In: Kwong RY, Editor. Cardiovascular Magnetic Resonance. Totowa, New Jersey: Humana Press, Inc.;2006. P429-466.
11. Al-Mallah M, Kwong RY. Cardiac MRI Assessment of Pericardial Disease. In: Kwong RY, editor. Cardiovascular Magnetic Resonance. Totowa, New Jersey: Humana Press, Inc.;2006. P. 467-490.
12. Ariyarajah V, Kwong RY. Valvular Heart Disease by Cardiac MRI. In: Kwong RY, editor. Cardiovascular Magnetic Resonance. Totowa, New Jersey: Humana Press, Inc.;2006. P. 491504.
13. Wu HD, Kwong RY. Cardiac Magnetic Resonance Imaging in Patients with Coronary Disease. Current Treatment Options in Cardiovascular Medicine. 2008;10(1):83-92.
14. Kwon S, Wu HD, Kwong RY. Myocardial Imaging in CAD: Beyond Ischemia and Viability. In: Di Carli MF, Kwong RY, editors. Novel Techniques in Imaging of the Heart. Hoboken, NJ: American Heart Association/Wiley-Blackwell, 2008. P. 295-304.
15. Steel K, Kwong RY. Pericardial Diseases. In: Manning WJ, editor. Atlas of Cardiovascular Magnetic Resonance Imaging, Imaging Companion to Braunwald's Heart Disease. Philadelphia, PA: Springer; 2008. P. 173-80.
16. Korlakunta H, Kwong RY. The Diagnostic and Prognostic Value of Cardiac MRI in Assessing Myocardial Viability. Topics in Magnetic Resonance Imaging. 2008;19(1):15-24.
17. Jerosch-Herold M, Kwong RY. Magnetic Resonance Imaging in the Assessment of Ventricular Remodeling and Viability. Curr Heart Fail Rep. 2008;5(1):5-10.
18. Steel KE, Kwong RY. Application of cardiac magnetic resonance imaging in cardiomyopathy. Curr Heart Fail Rep. 2008;5(3):128.
19. Kwong RY. Imaging the Physiology of the Ischemic Cascade: Are 2 Tools Better Than 1? Circ Cardiovasc Imaging. 2008;1(2):92-3.
20. Jerosch-Herold M, Kwong RY. Optimal Imaging Strategies to Assess Coronary Blood Flow and Risk for Patients with Coronary Artery Disease. Curr Opin Cardiol. 2008;23(6):599.
21. Kwong RY. Can Cardiac Magnetic Resonance Myocardial Scar Features Affect Treatment Decisions for Patients with Coronary Artery Disease and Heart Failure? JACC Cardiovasc Imaging. 2009;2:45-47.
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22. Tzemos N, Vorobiof G, Kwong RY. Dilated Cardiomyopathy and Myocardial Infarction. In: Kramer C, Hundley WG, editors. Atlas of Cardiac MR: Imaging Companion to Braunwald's Heart Disease. Philadelphia: Saunders Elsevier;2009. P. 121-32.
23. Kwong RY, Pfeffer MA. Infarct haemorrhage detected by cardiac magnetic resonance imaging: are we seeing the latest culprit in adverse left ventricular remodeling? Eur Heart J. 2009;30(12):1431-3.
24. Daly CA, Coelho-Filho OR, Kwong RY. Chronic Myocardial Ischemia and Viability. In: Kramer C, editor. Multimodality Imaging in Cardiovascular Medicine. New York: Demos Medical; 2009. P. 138-157.
25. Curillova Z, Kwong RY. MR and CT Imaging of Myocardial Viability.In: Ho V, Reddy GP, editors. Cardiovascular Imaging: Expert Radiology Series. St. Louis, MO: Elsevier Saunders;2010. P. 781-89.
26. Mercado K, Kwong RY. MR and CT Imaging of Myocardial Function. In: Ho V, Reddy GP, editors. Cardiovascular Imaging: Expert Radiology Series. St. Louis, MO: Elsevier Saunders;2010. P.751-70.
27. Coelho-Filho OR, Nallamshetty L, Kwong RY. Risk Stratification for Therapeutic Management and Prognosis. Heart Fail Clin. 2009;5(3):437-55, vii.
28. Meadows JL, Carballo D, Kwong RY. The prognostic value of cardiac MRI. Current Cardiovascular Imaging Reports: Cardiac Magnetic Resonance. 2009;2(2):145-56.
29. Carballo D, Meadows JL, Coelho O, Kwong RY. Cardiac Magnetic Resonance Imaging. In: Toth PP, Cannon CP, editors. Comprehensive Cardiovascular Medicine in the Primary Care Setting. New York: Humana /Springer; 2009. P. 567-80.
30. Francis SA, Coelho-Filho OR, Kwong RY. Classic images in cardiac MRI: a case-based atlas highlighting current applications of cardiac MRI. Curr Probl Cardiol. 2009;34(7):303-22.
31. Al-Mallah M, Kwong RY. Clinical Application of Cardiac CMR. Rev Cardiovasc Med. 2009;10(3):134-41.
32. Kwong RY. Magnetic Resonance Imaging. In: Libby P, editor. Essential Atlas of Heart Diseases. Newark, NJ: Springer; 2009. P. 359-375.
33. Gupta S, Kwong RY. MDCT Characterization of Microinfarction: Is it ready for clinical use? Radiology. 2010;254(3):637.
34. Kwong RY, Neilan TG. Characterizing post-myocardial infarction microvascular obstruction by ECG: we could learn more from cardiac magnetic resonance imaging. Rev Esp Cardiol. 2010;63(10):1120-2.
35. Daly CA, Coelho-Filho OR, Kwong RY. Recent Developments in Outcomes Research in Cardiovascular MRI. Curr Cardiovasc Imaging Rep. 2010;3:175-86.
36. Farzaneh-Far A, Kwong RY. Detecting Acute Coronary Syndromes by MRI. Heart and Metabolism. 2011;50:14-19.
37. Buckley O, Madan R, Kwong RY, Rybicki FJ, Hunsaker A. Cardiac masses, part 1: imaging strategies and technical considerations. Am J Roentgenol. 2011;197(5):W837-41.
38. Buckley O, Madan R, Kwong RY, Rybicki FJ, Hunsaker A. Cardiac masses, part 2: key imaging features for diagnosis and surgical planning. Am J Roentgenol. 2011;197(5):W842-51.
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39. Partington SL, Kwong RY, Dorbala S. Multimodality imaging in the assessment of myocardial viability. Heart Fail Rev. 2011;16(4):381-95.
40. Shah RV, Kwong RY. Tissue Characterization with Cardiac MR Imaging: A New Hope for Improving the Cardiac Outlook of Patients with Impaired Fasting Glucose? Radiology 2012;262(3):742-5.
41. Di Carli MF, Kwong RY, Jerosch-Herold M. Insights into left ventricular remodeling through noninvasive measures of myocardial matrix expansion with cardiovascular magnetic resonance, Circulation. 2012;126(10):1179-81.
42. Mongeon FP, Coelho-Filho O, Kwong RY. Cardiac MRI: Techniques and Protocols 2011. In: Abbara S, Kalva S, editors. Problem Solving in Radiology: Cardiovascular Imaging. Philadelphia: Elsevier; 2012. p. 79-90
43. Coelho-Filho OR, Rickers C, Kwong RY, Jerosch-Herold M. Magnetic Resonance Myocardial Perfusion Imaging. Radiology. 2013; 266(3):701-15. PMID: 23431226
44. Gupta D, Kwong RY, Pfeffer MA. Cardiovascular imaging in clinical practice: what does late gadolinium enhance? JAMA. 2013; 309(9):929-30
45. Daly C, Kwong RY. Cardiac MRI for Myocardial Ischemia. Methodist Debakey Cardiovasc J. 2013;9(3):123-131. Review. PMID:24066194
46. Farzaneh-Far A, Steigner M, Kwong RY. Applications and limitations of cardiac computed tomography in the evaluation of coronary artery disease. Coron Artery Dis. 2013;24(7):606-12. PMID: 24077228
47. Heydari B, Kwong RY. Cardiac magnetic resonance infarct heterogeneity: is it ready to be used on patients for the prevention of sudden cardiac death? Eur Heart J Cardiovasc Imaging. 2014;15(1):108-9 PMID: 24174301
48. Kwong RY, Jerosch-Herold M. Cardiac Magnetic Resonance And Amyloid Cardiomyopathy: Are We Getting Closer To The Biology? JACC Cardiovasc Imaging. 2014;7(2):166-168.
49. Heydari B, Kwong RY. Cardiac magnetic resonance imaging for ischemic heart disease: Update on Diagnosis and Prognosis. Top Magn Reson Imaging. 2014;23(1):21-31.
50. Shah RV, Abbasi SA, Kwong RY. Role of Cardiac MRI in Diabetes. Curr Cardiol Rep. 2014;16(2):449.
51. Heydari B, Kwong RY. Fractal dimension of hypertrophic cardiomyopathy trabeculation: a window to an unpredictable future? Circ Cardiovasc Genet. 2014;7(3):228-9.
52. Ghosh N, Kwong RY. It's time to study cardiac magnetic resonance imaging as a strategic tool in nonischemic cardiomyopathy. Circ Heart Fail. 2014;7(3):391-3.
53. Waller AH, Blankstein R, Kwong RY, Di Carli MF. Myocardial blood flow quantification for evaluation of coronary artery disease by positron emission tomography, cardiac magnetic resonance imaging, and computed tomography. Curr Cardiol Rep. 2014;16(5):483.
54. Jerosch-Herold M, Kwong RY. Cardiac T(1) imaging. Top Magn Reson Imaging. 2014 Feb;23(1):3-11. Review. PMID: 24509619
55. Kwong RY. MY APPROACH to selecting cardiac computed tomography vs cardiac magnetic resonance imaging vs. echocardiography. Trends Cardiovasc Med. 2015;25(1):70-1.
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56. Heydari B, Kwong RY, Jerosch-Herold M. Technical advances and clinical applications of quantitative myocardial blood flow imaging with cardiac MRI. Prog Cardiovasc Dis. 2015;57(6):615-22.
57. Kwong RY, Farzaneh-Far A. Assessment of LV Myocardial Scar Before Atrial Fibrillation Ablation. JACC Cardiovasc Imaging. 2015;8(7):801-3.
58. Morgan R, Kwong RY. Role of cardiac MRI in the assessment of cardiomyopathy. Current Treatment Options in Cardiovascular Medicine. 2015;17(11):53
59. Kwong RY. Chapter 18: Cardiovascular magnetic resonance imaging. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, editors. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Ninth Edition. Philadelphia: Saunders, 2012. page 340-361.
60. Kwong RY. Chapter 17: Cardiovascular magnetic resonance imaging. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, editors. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Tenth Edition. Philadelphia: Saunders, 2014. Page 320-340.
61. Di Carli MF, Kwong RY, Solomon SD. Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and Magnetic Resonance/Computed Tomography Imaging. In: Kasper DL, Fauci AS, Longo DL, Hauser SL, Jameson JL, Loscalzo J, editors. Harrison's Principles of Internal Medicine, 19th Edition. New York: McGraw-Hill Education, 2015. Chapter 270e: page 1459.
62. Di Carli MF, Kwong RY, Solomon SD. Atlas of Noninvasive Imaging. In: Kasper DL, Fauci AS, Longo DL, Hauser SL, Jameson JL, Loscalzo J, editors. Harrison's Principles of Internal Medicine, 19th Edition. New York: McGraw-Hill Education, 2015. Chapter 271e: page 1460.
63. Farzaneh-Far A, Kwong RY. Cardiovascular PET/MRI: We Need Evidence, Not Hype. J Nucl Cardiol. 2017;24(3):1032-1035.
64. Kwong RY, Shaw LJ, Nagel E. Can Stress CMR Impact Care in the Era After COURAGE and FAME-2? JACC Cardiovasc Imaging. 2017;10(5):538-540.
65. Morgan RB, Kwong RY. CMR in Phenotyping the Arrhythmic Substrate. Curr Cardiovasc Imaging Rep. 2017;10:19.
66. Kwong RY. Global Coronary Blood Flow Reserve at the Coronary Sinus: Can Old Tricks Find New Roles? J Am Coll Cardiol. 2017;70(7):880-2. PMID: 28797358
67. Kwong RY, Kramer CM, Chandrashekhar Y. ECV for Patients with Aortic Stenosis: Which Patient Will Benefit? JACC Cardiovasc Imaging. 2017;10(11):1408-9.
68. Kwong RY. T1 mapping in comparison to non-CMR methods of cardiac fibrosis. In: Yang PC, editor. T-1 Mapping in Myocardial Disease: Principles and Applications. London: Springer, 2018.
69. Kwong RY. Chapter 17: Cardiovascular magnetic resonance imaging. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, editors. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Eleventh Edition. Philadelphia: Saunders, 2018.
70. Morgan RB, Kwong RY. Role of cardiac MRI in assessment of cardiomyopathy: Cardiovascular Magnetic Resonance Imaging, Springer 2018.
71. Morgan R, Kwong RY. Assessment of Heart Failure By Cardiac MRI: Cardiovascular Magnetic Resonance Imaging, Springer 2018.
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72. Galazka P, Kwong RY. Valvular Heart Disease By Cardiac MRI, Cardiovascular Magnetic Resonance Imaging, Springer 2018.
73. Kwong RY, Ge Y, Nagel E. Are We Ready to Treat Dilated Cardiomyopathy Differently, Using LGE Guidance? JACC Cardiovasc Imaging. 2018 2018 Sep 6. pii: S1936878X(18)30726-5.
74. Kwong RY, Kramer CM, Chandrashekhar Y. CMR Global Longitudinal Strain: A Better Tool for Unraveling the Links to Heart Failure Mortality. JACC Cardiovascular Imaging 2018 Oct;11(10):1554-1555
75. Kwong RY, Ge Y. Cardiac Magnetic Resonance as a Window Into Cardiac Allograft Tissue Health: A Step Toward Freedom from Endomyocardial Biopsies. JACC Cardiovasc Imaging. 2019 Mar 8. pii: S1936-878X(19)30157-3. doi: 10.1016/j.jcmg.2018.12.030. [Epub ahead of print] No abstract available. PMID: 30878426
76. Kwong RY, Bax JJ. Unraveling the Complex Process of Adverse Cardiac Remodeling. Circulation Cardiovascular Imaging. 2019 May;12(5): e009086. doi: 10.1161/CIRCIMAGING.119.009086. No abstract available. PMID: 31109183
Books/Textbooks for the medical or scientific community
1. Kwong RY (Editor). Cardiovascular Magnetic Resonance Imaging. First Edition. Contemporary Cardiology Series. Totowa, New Jersey: Humana Press; 2007.
2. Di Carli MF, Kwong RY (Editors). Novel Techniques in Imaging of the Heart. Hoboken, NJ: American Heart Association/Wiley-Blackwell, 2008.
3. Kwong RY, Jerosch-Herold M, Heydari B (Editors). Cardiovascular Magnetic Resonance Imaging. Second Edition. New York: Springer; 2018. Case Reports
1. Yan AT, Coffey DM, Li Y, Chan WS, Shayne AJ, Luu TM, Skorstad RB, Khin MM, Brown KA, Lipton MJ, Kwong RY. Myocardial Fibroma in Gorlin Syndrome by Cardiac Magnetic Resonance Imaging. Circulation, Images in Cardiovascular Medicine. 2006;114:32-39.
2. Ates M, Kwong RY, Lipton MJ, Tatli S. Apical Hypertrophic Cardiomyopathy Diagnosed by Cardiac Magnetic Resonance Imaging. Tex Heart Inst J. 2006;33(3):408-9.
3. Sah R, Epstein LM, Kwong RY. Images in Cardiovascular Medicine: Intramural Atrial Hematoma following Catheter Ablation for Atrial Tachyarrhythmias. Circulation. 2007;115(18):e446-447.
4. Thomas D, Grant FD, Kwong RY, Nose V, Di Carli MF, Dorbala S. Multimodality imaging of an unusual case of cardiac paraganglioma. J Nucl Cardiol. 2009; 16(4):644-7.
5. Basic D, Gupta S, Kwong RY. Parvovirus b19-induced myocarditis mimicking acute myocardial infarction: clarification of diagnosis by cardiac magnetic resonance imaging. Circulation. 2010;121(7): e40-2.
6. Coelho-Filho OR, Rajaram M, Jerosh-Herold M, Abdullah S, Carballo D, Feitosa L, Francis S, John R, Blankstein R, Kwong RY. Images in Cardiovascular Medicine: Solitary fatty
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infiltration within the left ventricle detected by cardiac magnetic resonance imaging in a patient presenting with ventricular tachycardia. Circulation. 2009; 120(11): 1008-10. 7. Partington SL, Ali B, Daly RP, Koplan BA, Lilly LS, Solomon SD, Kwong RY, Blankstein R. Images in Cardiovascular Medicine: Initial presentation of an accessory left ventricle in a patient with syncope. Circulation. 2010;121(19):e401-3.
8. Coelho-Filho OR, Mongeon FP, Mitchell RN, Blankstein R, Jerosch-Herold M, Kwong RY. Images in Cardiovascular Medicine. Loeffler endocarditis presenting with recurrent polymorphic ventricular tachycardia diagnosed by cardiac magnetic resonance imaging. Circulation. 2010; 122(1):96-9.
9. Buckley O, DeVore A, Ersoy H, Sobieszczyk P, Auger WR, Kwong R, Rybicki FJ, Goldhaber SZ. Embolism after inferior vena cava filter mesh fragmentation. J Vasc Interv Radiol. 2010;21(11):1782-4.
10. Azran MS, Kwong RY, Chen FY, Shernan SK. A potential use for intraoperative threedimensional transesophageal echocardiography in predicting left ventricular chamber dimensions and ejection fraction after aneurysm resection. Anesth Analg. 2010;111(6):1362-5.
11. Partington SL, Givertz MM, Gupta S, Kwong RY. Cardiac magnetic resonance aids in the diagnosis of mitochondrial cardiomyopathy. Circulation. 2011;123(6):e227-9.
12. Lee MS, Pande RL, Rao B, Landzberg MJ, Kwong RY. Cerebral abscess due to persistent left superior vena cava draining into the left atrium. Circulation. 2011;124(21):2362-4
13. Mousavi N, Shook D, Kilcullen N. Aranki S, Kwong RY, Landzberg MJ, Blankstein R. Multimodality Imaging of a Gerbode Defect. Circulation. 2012; 126(1): e1-e2.
14. Robinson BL, Kwong RY, Varma PK, Wolfe M, Couper G. Magnetic resonance imaging of complex partial anomalous pulmonary venous return in adults. Circulation. 2014;129(1):e1-2. PubMed PMID: 24396018.
15. Liu H, Juan YH, Liang C, Chen J, Liang S, Xie Z, Kwong RY, Saboo SS. Multidetector computed tomographic angiography imaging of pentalogy of Cantrell. Circulation. 2014;129(15):1618-20.
Letters to the Editor 1. Selvadurai BSN, Puntmann VO, Bluemke DA, Ferrari VA, Friedrich MG, Kramer CM, Kwong RY, Lombardi M, Prasad SK, Rademakers FE, Young AA, Kim RJ, Nagel E. Definition of Left Ventricular Segments for Cardiac Magnetic Resonance Imaging. JACC Cardiovasc Imaging. 2018;11(6):926-28.
Professional educational materials or reports, in print or other media 1. Kwong RY. Pericardium: Pericardial disease. American College of Cardiology (ACC) Cardiac MRI Self Assessment Program (CMR-SAP). 2004.
2. Sanz J, Bax J, Kwong RY. Medical Round Table Discussion: Evolving Diagnostic and Prognostic Imaging (MR, CT) of the Various Cardiomyopathies: Myocarditis, Dilated, Infiltrative (Amyloid, Sarcoid), Hypertrophic, Noncompaction. September 28, 2011. Med Roundtable Cardiovasc Ed. 2011;2(4):216-223.
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3. Cardiosource Video Network Interview for JACC Cardiovascular Imaging: Stress Myocardial Perfusion Imaging by Cardiac Magnetic Resonance Provides Strong Prognostic Value to Cardiac Events Regardless of Patient's Gender. April 3, 2011. Annual Scientific Session of the American College of Cardiology. Full interview can be viewed at www.cardiosource.org.
4. Cardiosource Video Network Interview for JACC Cardiovascular Imaging: Late Gadolinium Enhancement Among Survivors of sudden cardiac arrest. Annual Scientific Session of the American College of Cardiology 2015, San Diego, CA. Full interview can be viewed at www.cardiosource.org.
5. Interview for American College of Cardiology's international audio journal of contemporary cardiovascular medicine and surgery. The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Registry Study. European Society of Cardiology Congress, Munich, Germany.
6. Video interview for Radcliff Cardiology. The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Registry Study. European Society of Cardiology Congress, Munich, Germany.
Clinical Guidelines and Reports
1. Kwong RY. Dobutamine Stress Magnetic Resonance Imaging. Radiology Today. 2003;3(7). 2. Fishman GI, Chugh SS, Dimarco JP, Albert CM, Anderson ME, Bonow RO, Buxton AE, Chen
PS, Estes M, Jouven X, Kwong R, Lathrop DA, Mascette AM, Nerbonne JM, O'Rourke B, PageRL, Roden DM, Rosenbaum DS, Sotoodehnia N, Trayanova NA, Zheng ZJ. Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation. 2010;122(22):2335-48. 3. Hendel RC, Berman DS, Di Carli MF, Heidenreich PA, Henkin RE, Pellikka PA, Pohost GM, Williams KA, Wolk MJ, Alagona P Jr, Bateman TM, Cerqueira MD, Corbett JR, Dean AJ, Dehmer GJ, Goldbach P, Gordon L, Kushner FG, Kwong RY, Min J, Quinones MA, Ward RP, Yang SH, Allen J, Brindis RG, Douglas PS, Patel M, Peterson E. ACCF/ASNC/ACR/AHA/ ASE/ SCCT/SCMR/SNM 2009 appropriate use criteria for cardiac radionuclide imaging: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine: endorsed by the American College of Emergency Physicians. Circulation. 2009;119(22):e561-87. 4. Hundley WG, Bluemke D, Bogaert JG, Friedrich MG, Higgins CB, Lawson MA, McConnell MV, Raman SV, van Rossum AC, Flamm S, Kramer CM, Nagel E, Neubauer S. Society for Cardiovascular Magnetic Resonance guidelines for reporting cardiovascular magnetic resonance examinations. J Cardiovasc Magn Reson. 2009,11:5. (I assisted in Chinese translation of this document for the Society for Cardiovascular Magnetic Resonance) 5. Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, Douglas PS, Foody JM, Gerber TC, Hinderliter AL, King SB 3rd, Kligfield PD, Krumholz HM, Kwong RY, Lim MJ, Linderbaum JA, Mack MJ, Munger MA, Prager RL, Sabik JF, Shaw LJ, Sikkema JD, Smith
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CR Jr, Smith SC Jr, Spertus JA, Williams SV. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/ STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: Executive Summary. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2012;60(24):2564-603. Also published in: Circulation. 2012;126(25):3097-137.
6. Kramer CM, Hundley WG, Kwong RY, Martinez MW, Raman SV, Ward RP. COCATS 4 Task Force 8: Training in Cardiovascular Magnetic Resonance Imaging. J Am Coll Cardiol. 2015;65(17):1822-31.
7. Shaw LJ, Blankstein R, Jacobs JE, Leipsic JA, Kwong RY, Taqueti VR, Beanlands RS, Mieres JH, Flamm S, Gerber TC, Spertus J, Di Carli MF. Defining Quality in Cardiovascular Imaging: A Scientific Statement From the American Heart Association. Circ Cardiovasc Imaging. 2017;10(12). pii: e000017.
Abstracts, Poster Presentations and Exhibits Presented at Professional Meetings
1.
Hsiao E, Abdullah S, Carballo D, Gupta S, Coelho OR, Seabra L, Mongeon FP, Blankstein R,
Kwong RY. Fragmented QRS complex and late gadolinium enhancement characterization of
unrecognized myocardial scar provided complementary prognosis of cardiac death in patients
with suspected coronary artery disease. Oral presentation by Dr. Hsiao. Finalist for Clinical
Early Career Award at SCMR Scientific Sessions, Phoenix, AZ, 2010.
2.
Coelho-Filho OR, Seabra FL, Gupta S, Francis SA, Blankstein R, Jerosch-Herold M, Kwong
RY. Combined stress myocardial perfusion and late gadolinium enhancement imaging by
cardiac magnetic resonance provides robust prognostic data to cardiac events. Oral presentation by Dr. Coelho-Filho at 14th Annual SCMR Scientific Sessions, Nice, France,
2011. Recipient of the Clinical Early Career Award of SCMR, 2011.
3.
Abbasi S, Kwong RY. Infarct Tissue Heterogeneity by Contrast-Enhanced MRI Is a Novel
Predictor of Mortality in Patients with Chronic Coronary Artery Disease and Left Ventricular Dysfunction. Massachusetts Chapter, American College of Cardiology (ACC) Annual Meeting, 2012, Waltham, MA. Recipient of Fellow abstract award, 2012.
4.
Gräni C, Eichhorn C, Bière L, Murthy VL, Agarwal V, Kaneko K, Cuddy S, Aghayev A,
Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Prognostic Value of Cardiac
Magnetic Resonance Imaging Tissue Characterization in Risk Stratification of Patients Presenting with Suspected Myocarditis, Poster presentation European Society of Cardiology, Barcelona, Spain 2017.
5.
Gräni C, Eichhorn C, Bière L, Murthy VL, Agarwal V, Kaneko K, Cuddy S, Aghayev A,
Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Risk stratifying patients with
suspected myocarditis with extracellular volume assessment by cardiovascular magnetic
resonance imaging. Oral Presentation by Gräni C. ACC Annual Scientific Sessions, 2018
6.
Gräni C, Eichhorn C, Bière L, Murthy VL, Agarwal V, Kaneko K, Cuddy S, Aghayev A,
Steigner M, Blankstein R, Jerosch-Herold M, Kwong RY. Comparing Myocardial Fibrosis
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Quantification Methods For Risk Stratification in Patients With Suspected Myocarditis Using Cardiac Magnetic Resonance Imaging. Oral Presentation by Gräni C. EuroCMR/SCMR, Barcelona. 2018
Narrative Report
As a clinical cardiologist, I have dedicated my clinical skills to providing general cardiology care to patients across a full range of cardiac conditions. Since I joined faculty in 2001, I have enhanced clinical care at BWH by creating and growing the capabilities of the cardiovascular magnetic resonance (CMR) program to all caring clinicians. I was able to channel the anatomical and physiological knowledge gained by CMR to serve clinicians and patients in need, incremental to existing imaging methods such as echocardiography and nuclear scintigraphy. Our CMR program was the first and remains the only such program in New England that provides stress CMR assessment for risk stratifying patients with chest pain syndromes.
Combining my skills in clinical cardiology, CMR imaging, and software development, I created a webbased de-identified secure CMR and CT reporting system (https://cmrcoop.partners.org) that allows accurate quantitative imaging reporting that adheres to all governing guidelines. This effort had since then transformed into an international collaborative consortium promoting consistency of performance and reporting of CMR/CT imaging with an ongoing vision in shaping multicenter research assessing imaging cost-effectiveness, cardiovascular outcomes, and real-world impact in patient care. This effort has attracted the attention of the Society for Cardiovascular Magnetic Resonance (SCMR), which officially endorsed our consortium towards development of an international imaging registry. I have been appointed and served as the Chair of the SCMR global registry committee (https://gcmr.bwh.harvard.edu) and continue to oversee all aspects of its growth and directions, with currently 40 international tertiary centers actively participating. As a key effort of the SCMR registry, we initiated a multicenter study in 2016 assessing the clinical impact and cost-effectiveness of CMR imaging of patients with stable chest pain syndromes: The Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A SCMR Registry Study. The results of this 13-center, 2,371 patient study demonstrated the real-world clinical impact and cost-effectiveness of stress CMR imaging in the United States. The results of the SPINS study were presented at the European Society of Cardiology Congress in Munich, Germany in August 2018.
I have received international recognition in my work and have represented BWH in numerous capacities. I served as the Program Co-Chair and Program Chair of the Annual Scientific Meeting of the Society for Cardiovascular Magnetic Resonance (SCMR). I also served SCMR as a voting member of the Board of Trustees for a 3-year term as well as Chair or co-Chair of various international committees. I have represented BWH over the past 10 years in various NIH study sections, including the past 4 years as a permanent member of the Clinical Integrated Cardiovascular Science (CICS) Study Section. I had served for many years as an Editorial Board member for Circulation, Circulation Cardiovascular
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Imaging, the Journal of the American College of Cardiology (JACC), and the Journal of Cardiovascular Magnetic Resonance (JCMR). In addition, I am currently an Associate Editor of JACC Cardiovascular Imaging and the JCMR.
My clinical research focuses on treatment and imaging approaches for coronary artery disease and other forms of cardiomyopathy. I led the BWH CMR program in investigating and publishing landmark manuscripts that informed the CMR imaging community regarding the prognostic utility and management implication of LGE imaging of myocardial infarction. As PI of a NIH R01 study, I aligned the efforts of 3 teaching centers (BWH, MGH, and BIDMC) and conducted a randomized control trial of survivors of acute myocardial infarction. We observed significant beneficial effects of high dose omega3 fatty acids in attenuating adverse cardiac remodeling incremental to guideline-based optimized interventional and medical therapies. Our results supported the notion that suppression of systemic and myocardial inflammation using omega-3 fatty acids provides a safe and unique treatment promoting inflammatory resolution and myocardial healing after an acute myocardial infarction. These results were published in Circulation and were cited in > 162 news outlets (including Reuters Health, Times, WebMD, Drugs.com) and viewed by > 151 million viewers in the first 4 months of publication. We further discovered supporting evidence that genetic polymorphism exists in the response to omega-3 fatty acids, leading to a patent application. These results may have strong implication in reducing the high burden of post-MI heart failure and personalized treatment using patients' genotypes and biomarker profiles. Other investigations I had led include risk stratification of diabetic patients with respect to coronary artery disease and survivors of cardiac arrests. I have led efforts to develop an extensive CMR core laboratory at BWH, and we have been able to provide high-quality CMR analyses for 12 funded clinical trials towards discovery of novel drug therapies.
I was a founding member of the Noninvasive Cardiovascular Imaging (NCVI) program, a joint effort of the Division of Cardiovascular Medicine and the Department of Radiology at BWH. I provide not only imaging consultation to clinicians but also training of future imaging experts in both radiology and cardiology. The NCVI program has been recognized internationally as a fertile environment for innovative research, training, and patient care. My other teaching activities include clinical supervision of medical students, residents, fellows, and faculty in CMR and echocardiography. I have taught in BWH/HMS CME courses, and I have mentored numerous trainees who have published papers in highimpact journals and secured faculty positions at major academic institutions.
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