3. For applied testing . Robust and easy to use, the iCAP TQe ICP-MS is a . compact and low maintenance instrument. Daily analysis . is elevated to a new level and the high matrix tolerance
Thermo Scientific iCAP TQe ICP-MS Redefining triple quadrupole ICP-MS with unique ease of use iCAP TQe ICP-MS Overcome unexpected interferences, reduce detection limits for critical contaminants and improve data quality Leverage superior interference removal using triple quadrupole (TQ) ICP-MS for uncomplicated analysis with incredible accuracy. Expand your applications and enhance your laboratory efficiency with this breakthrough technology, which is so easy to use that it can be operated by any analyst. · Reaction Finder method development assistant enables you to tackle challenging matrices without complex, time-consuming method development · Common Thermo ScientificTM QtegraTM Intelligent Scientific Data SolutionTM (ISDS) software platform allows analysts to switch easily between ICP techniques · Minimal installation and bench space requirements The Thermo ScientificTM iCAPTM TQe ICP-MS is the optimal solution for future-proofing elemental analysis in your laboratory, explore developing markets, increase productivity and meet the requirements of evolving legislation. · Right-first-time analysis with powerful interference removal, even in the toughest matrices · Reduced re-runs in the daily workload with assured accuracy and repeatability · Maintained flexibility of single quadrupole (SQ) mode for less challenging analyses 2 For applied testing Robust and easy to use, the iCAP TQe ICP-MS is a compact and low maintenance instrument. Daily analysis is elevated to a new level and the high matrix tolerance and exceptional interference removal, even in challenging sample matrices, open up new applications. Simplified operation from Qtegra ISDS software means operators do not need to be specialists. For research Improved interference removal leads to the lower detection limits that are essential for new scientific breakthroughs. Find out what is possible with the advanced performance of TQ-ICP-MS technology. 3 Inside TQ technology Highly effective interference removal for accurate and reliable results · The iCAP TQe ICP-MS achieves consistent interference removal regardless of the sample composition using just helium and oxygen as the collision/reaction cell gases. This simplifies operation and eliminates the need for special gas installation in the laboratory. · If SQ analysis is required, switching between preset Kinetic Energy Discrimination (KED) mode and TQ modes is possible in a single sample analysis for rapid and reliable results. · The Reaction Finder Method Development Assistant dramatically simplifies method development. No requirement for advance knowledge of complex reaction chemistry is necessary--Reaction Finder does it for you! Let Reaction Finder select the right mode for your analysis SQ mode: Comparable to SQ-ICP-MS instruments, Q1 transmits all masses TQ on mass mode: Q1 and Q3 set to the same mass TQ mass shift mode: Q1 and Q3 set to different masses 91[AsO] 111Cd Q3 set to product ion mass (m/z 91) 150Nd, 150Sm 40Ar35Cl Q3 set to product ion mass (m/z 111) MoO2 Q2 filled with reactive gas (O2 ) 75As is converted into 75As16O Q2 filled with reactive gas (O2 ) 95Mo16O forms higher oxide products such as MoO2 Q1 set to analyte mass (m/z 75) 150Nd, S 150 m, 91Zr 75As, 150Nd, S 150 m, 40Ar35Cl "Mass Shift" 4 Q1 set to analyte mass (m/z 111) 95Mo 111Cd, 95Mo16O "On Mass" Technology at a glance QCell CRC enables single mode analysis with complete interference removal using He KED and/or reactive chemistry with oxygen Innovative design with optimized ion transmission in Q1. Intelligent Mass Selection (iMS) allows effective suppression of unwanted side reactions whilst assuring sensitivity RAPID lens for effective and focused 90° ion deflection, enabling zero user maintenance beyond the interface Range of interfaces provide full instrument flexibility, from maximum robustness to highest sensitivity Instrument stability and reliability enabled by the solid state, swing frequency RF generator with virtual grounding and optimized electronics Quick-connect, self-aligning sample introduction system, no shield or bonnet required Drop-down door for easy interface access 5 Ultimate ease of use Qtegra Intelligent Scientific Data Solution Software Intuitive, cross-platform software enables easy and straightforward operation, from plasma ignition to data acquisition and from reporting to routine maintenance. Get up and running in just five clicks! Reaction Finder Method Development Assistant Streamline your workflow with Reaction Finder. Use this intuitive feature to achieve optimal interference removal for your target analytes via intelligent measurement mode selection. · Removes the complexity from TQ technology · Automatically selects the isotope, reaction gas and product ion · Dramatically decreases method development time · Enables accessibility to all users · Provides the confidence of accurate data Intelligent data assessment With the sheer volume of data generated in busy laboratories, result-dependent decisions cannot wait for manual data assessment. Qtegra ISDS software includes an intuitive set of tools (e.g., flexible Quality Control (QC) rules, analysis specific limits) to aid in data visualization, interpretation and fully automated run control. Enhance your productivity through automated sample handling, managed within the simple interface of Qtegra ISDS software. Routinely tackle advanced applications with hyphenated techniques to expand your application capabilities. 6 LIMS integration Qtegra ISDS software includes full integration with laboratory information management system (LIMS) software. Complete analysis descriptions can be directly imported into Qtegra ISDS software, eliminating additional user input, and full results (both analytical as well as metadata) are immediately available after analysis for rapid turnaround of results. 1. Choose method template for analysis 2. Import sample information 3. Perform analysis 4. Automatically export results Speciation The ChromControl plug-in for Qtegra ISDS software provides control of chromatography systems for automated sample analysis in a single software. Additionally, dedicated chromatographic data processing and compound quantification features deliver simple and reliable speciation analysis. Comprehensive regulatory compliance Full system qualification, comprehensive audit trails and integrated regulatory tools in the Qtegra ISDS software enable simplified system validation and performance qualification, total data security and audit assurance. Autodilution Fully integrated control of auto dilution peripherals in Qtegra ISDS software, delivering error-free prescriptive and intelligent dilution options. 7 Applied analytical testing Be ready to meet the most demanding challenges in protecting our future Environmental health The iCAP TQe ICP-MS is a powerful solution for accurately quantifying trace analytes in the most challenging environmental matrices. Avoid unwanted interruptions to the daily workplan with a combination of SQ and TQ interference removal modes. Food safety Remove uncertainty from food safety analysis and be prepared for future legislation with speciation and nanoparticle characterization capabilities. Even the most challenging matrices are no obstacle for the iCAP TQe ICP-MS, ensuring reliable elemental analysis to support production of safe, high quality food and beverage products. Pharmaceutical compliance Comply with confidence. Meet global regulatory standards, including FDA, U.S. Pharmacopeia chapters <232> / <233>, and ICH Q3D, and explore new areas such as extractables and leachables using the superior detection capability of the iCAP TQe ICP-MS. Clinical accuracy Advance your clinical research with total confidence provided by superior interference removal. Use Reaction Finder to determine the appropriate measurement mode for your specific application and easily obtain accurate results. Perform robust and rapid analyses, even with small volume or complex matrix samples, such as blood and urine. Analyte Challenge Solution Benefit Arsenic Selenium Abundant chlorine-based polyatomics and doubly charged interferences of samarium and neodymium Intense argon-based polyatomics on the most abundant isotope (selenium-80); doubly charged interferences of gadolinium Cadmium Mercury Higher concentrations of molybdenum, naturally occurring in a variety of foods, may lead to false positives Even low levels of tungsten can lead to incorrect results for this critical contaminant, due to formation of tungsten oxide interferences *Compared to the use of He KED mode on a single quadrupole ICP-MS Only TQ technology eliminates all these potential interferences Greater confidence in results Significantly improved sensitivity and detection limit * Reliable ultra-trace analysis in every sample matrix 8 9 Industrial applications Advance developments in metals, materials and chemical production Metallurgy Optimize geochemical exploration and mining profitability with accurate quantitation of trace elements and impurities essential to metallurgy research and industrial production. Confidently measure bulk and spatial distributions with laser ablation. Material science Ensure product quality and accurately determine impurities in raw materials for industrial applications. The iCAP TQe ICP-MS is the robust solution required to analyze complex samples quickly and accurately. Chemicals Directly measure impurities in aggressive mineral acids or organic solvents with the ultra-low detection limits delivered by high performance triple quadrupole technology. The robust plasma ensures reliable analysis in the toughest of matrices. Energy production Effectively monitor the fracking process or determine the ageing state and degradation of energy consumables. The iCAP TQe ICP-MS easily provides the required detection power. Take on new challenges with significantly reduced detection limits Eliminate mathematical correction and interference correction solutions from your workflow Leverage single mode analysis using triple quadrupole ICP-MS for full interference removal and accelerate sample turnaround times Reduced sample turnaround times Increased throughput Increased return on investment 10 11 Thermo ScientificTM iCAPTM Qnova Series ICP-MS For easy, powerful and routine SQ-ICP-MS and TQ-ICP-MS analysis. Find out more at thermofisher.com/TQ-ICP-MS For Research Use Only. Not for use in diagnostic procedures. © 2021 Thermo Fisher Scientific Inc. All rights reserved. CETAC is a trademark of Teledyne Instruments Incorporated. Teledyne is a trademark of Teledyne Technologies Incorporated. FDA is used in trade by the United States Food and Drug Administration. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. 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