SDS / TDS
838 Total Ground Carbon Conductive Coating MG Chemicals UK Limited Version No: A-1.01 Safety Data Sheet (Conforms to Regulation (EU) No 2015/830) Issue Date: 28/10/2019 Revision Date: 17/03/2020 L.REACH.GBR.EN SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING 1.1. Product Identifier Product name Synonyms Other means of identification 838 SDS Code 838-Liquid; 838-900ML, 838-1G Total Ground Carbon Conductive Coating 1.2. Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses Uses advised against Electrically conductive coating for preventing static buildups and providing EMI/RFI shielding Not Applicable 1.3. Details of the supplier of the safety data sheet Registered company name Address Telephone Fax Website Email MG Chemicals UK Limited Heame House, 23 Bilston Street, Sedgely Dudley DY3 1JA United Kingdom +(44) 1663 362888 Not Available Not Available sales@mgchemicals.com MG Chemicals (Head office) 9347 - 193 Street Surrey V4N 4E7 British Columbia Canada +(1) 800-201-8822 +(1) 800-708-9888 www.mgchemicals.com Info@mgchemicals.com 1.4. Emergency telephone number Association / Organisation Emergency telephone numbers Other emergency telephone numbers Verisk 3E (Access code: 335388) +(44) 20 35147487 +(0) 800 680 0425 SECTION 2 HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture Classification according to regulation (EC) No 1272/2008 [CLP] [1] Legend: H336 - Specific target organ toxicity - single exposure Category 3 (narcotic effects), H373 - Specific target organ toxicity - repeated exposure Category 2, H225 - Flammable Liquid Category 2, H315 - Skin Corrosion/Irritation Category 2, H319 - Eye Irritation Category 2, H361 Reproductive Toxicity Category 2, H304 - Aspiration Hazard Category 1, H351 - Carcinogenicity Category 2 1. Classified by Chemwatch; 2. Classification drawn from Regulation (EU) No 1272/2008 - Annex VI 2.2. Label elements Hazard pictogram(s) SIGNAL WORD DANGER Hazard statement(s) H336 H373 H225 H315 H319 H361 H304 H351 May cause drowsiness or dizziness. May cause damage to organs through prolonged or repeated exposure. Highly flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. Suspected of damaging fertility or the unborn child. May be fatal if swallowed and enters airways. Suspected of causing cancer. Continued... Page 2 of 24 838 Total Ground Carbon Conductive Coating Supplementary statement(s) Not Applicable Precautionary statement(s) Prevention P201 P210 P260 P271 P280 P240 P241 P242 P243 Obtain special instructions before use. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not breathe mist/vapours/ spray. Use in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Ground and bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/intrinsically safe equipment. Use non-sparking tools. Take action to prevent static discharges. Precautionary statement(s) Response P301+P310 P308+P313 P321 P331 P370+P378 P305+P351+P338 P312 P337+P313 P302+P352 P303+P361+P353 P304+P340 P332+P313 P362+P364 IF SWALLOWED: Immediately call a POISON CENTER/doctor/physician/first aider. IF exposed or concerned: Get medical advice/ attention. Specific treatment (see advice on this label). Do NOT induce vomiting. In case of fire: Use alcohol resistant foam or normal protein foam to extinguish. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER/doctor/physician/first aider/if you feel unwell. If eye irritation persists: Get medical advice/attention. IF ON SKIN: Wash with plenty of water. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. IF INHALED: Remove person to fresh air and keep comfortable for breathing. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash it before reuse. Precautionary statement(s) Storage P403+P235 P405 Store in a well-ventilated place. Keep cool. Store locked up. Precautionary statement(s) Disposal P501 Dispose of contents/container to authorised hazardous or special waste collection point in accordance with any local regulation. SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS 3.1.Substances See 'Composition on ingredients' in Section 3.2 3.2.Mixtures 1.CAS No 2.EC No 3.Index No 4.REACH No 1.108-88-3 2.203-625-9 3.601-021-00-3 4.01-2119471310-51XXXX|01-2120766415-50-XXXX 1.110-19-0 2.203-745-1 3.607-026-00-7 4.01-2119488971-22-XXXX 1.110-43-0 2.203-767-1 3.606-024-00-3 4.01-2119902391-49XXXX|01-2120752829-39-XXXX 1.67-64-1 2.200-662-2 3.606-001-00-8 4.01-2119471330-49-XXXX %[weight] Name 27 toluene * 8 isobutyl acetate 8 amyl methyl ketone * 7 acetone * Classification according to regulation (EC) No 1272/2008 [CLP] Flammable Liquid Category 2, Reproductive Toxicity Category 2, Specific target organ toxicity - single exposure Category 3 (narcotic effects), Specific target organ toxicity repeated exposure Category 2, Skin Corrosion/Irritation Category 2, Aspiration Hazard Category 1; H225, H361d ***, H336, H373 **, H315, H304 [2] Flammable Liquid Category 2; H225, EUH066 [2] Flammable Liquid Category 3, Acute Toxicity (Oral) Category 4, Acute Toxicity (Inhalation) Category 4; H226, H302, H332 [2] Flammable Liquid Category 2, Specific target organ toxicity - single exposure Category 3 (narcotic effects), Eye Irritation Category 2; H225, H336, H319, EUH066 [2] Continued... Page 3 of 24 838 Total Ground Carbon Conductive Coating 1.64-17-5 2.200-578-6 3.603-002-00-5 4.01-2119457610-43-XXXX 7 ethanol Flammable Liquid Category 2; H225 [2] 1.141-78-6 2.205-500-4 3.607-022-00-5 4.01-2119475103-46XXXX|01-2120767619-37-XXXX Flammable Liquid Category 2, Specific target organ toxicity - single exposure Category 3 4 ethyl acetate * (narcotic effects), Eye Irritation Category 2; H225, H336, H319, EUH066 [2] 1.108-65-6 2.203-603-9 3.603-064-00-3|607-195-00-7|603-106-00-0 1 4.01-2119457435-35XXXX|01-2119475791-29-XXXX propylene glycol monomethyl ether mixture of isomers * Flammable Liquid Category 3; H226 [2] Legend: 1. Classified by Chemwatch; 2. Classification drawn from Regulation (EU) No 1272/2008 - Annex VI; 3. Classification drawn from C&L; * EU IOELVs available SECTION 4 FIRST AID MEASURES 4.1. Description of first aid measures Eye Contact If this product comes in contact with the eyes: Wash out immediately with fresh running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. Skin Contact If skin or hair contact occurs: Immediately flush body and clothes with large amounts of water, using safety shower if available. Quickly remove all contaminated clothing, including footwear. Wash skin and hair with running water. Continue flushing with water until advised to stop by the Poisons Information Centre. Transport to hospital, or doctor. Inhalation If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay. Ingestion If spontaneous vomiting appears imminent or occurs, hold patient's head down, lower than their hips to help avoid possible aspiration of vomitus. If swallowed do NOT induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. Observe the patient carefully. Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious. Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink. Seek medical advice. Avoid giving milk or oils. Avoid giving alcohol. 4.2 Most important symptoms and effects, both acute and delayed See Section 11 4.3. Indication of any immediate medical attention and special treatment needed Any material aspirated during vomiting may produce lung injury. Therefore emesis should not be induced mechanically or pharmacologically. Mechanical means should be used if it is considered necessary to evacuate the stomach contents; these include gastric lavage after endotracheal intubation. If spontaneous vomiting has occurred after ingestion, the patient should be monitored for difficult breathing, as adverse effects of aspiration into the lungs may be delayed up to 48 hours. Following acute or short term repeated exposures to toluene: Toluene is absorbed across the alveolar barrier, the blood/air mixture being 11.2/15.6 (at 37 degrees C.) The concentration of toluene, in expired breath, is of the order of 18 ppm following sustained exposure to 100 ppm. The tissue/blood proportion is 1/3 except in adipose where the proportion is 8/10. Metabolism by microsomal mono-oxygenation, results in the production of hippuric acid. This may be detected in the urine in amounts between 0.5 and 2.5 g/24 hr which represents, on average 0.8 gm/gm of creatinine. The biological half-life of hippuric acid is in the order of 1-2 hours. Primary threat to life from ingestion and/or inhalation is respiratory failure. Patients should be quickly evaluated for signs of respiratory distress (eg cyanosis, tachypnoea, intercostal retraction, obtundation) and given oxygen. Patients with inadequate tidal volumes or poor arterial blood gases (pO2 <50 mm Hg or pCO2 > 50 mm Hg) should be intubated. Arrhythmias complicate some hydrocarbon ingestion and/or inhalation and electrocardiographic evidence of myocardial damage has been reported; intravenous lines and cardiac monitors should be established in obviously symptomatic patients. The lungs excrete inhaled solvents, so that hyperventilation improves clearance. A chest x-ray should be taken immediately after stabilisation of breathing and circulation to document aspiration and detect the presence of pneumothorax. Epinephrine (adrenaline) is not recommended for treatment of bronchospasm because of potential myocardial sensitisation to catecholamines. Inhaled cardioselective bronchodilators (e.g. Alupent, Salbutamol) are the preferred agents, with aminophylline a second choice. Lavage is indicated in patients who require decontamination; ensure use. BIOLOGICAL EXPOSURE INDEX - BEI These represent the determinants observed in specimens collected from a healthy worker exposed at the Exposure Standard (ES or TLV): Determinant Index Sampling Time o-Cresol in urine 0.5 mg/L End of shift Hippuric acid in urine 1.6 g/g creatinine End of shift Toluene in blood 0.05 mg/L Prior to last shift of workweek Comments B B, NS NS: Non-specific determinant; also observed after exposure to other material Continued... Page 4 of 24 838 Total Ground Carbon Conductive Coating B: Background levels occur in specimens collected from subjects NOT exposed SECTION 5 FIREFIGHTING MEASURES 5.1. Extinguishing media Foam. Dry chemical powder. BCF (where regulations permit). Carbon dioxide. Water spray or fog - Large fires only. 5.2. Special hazards arising from the substrate or mixture Fire Incompatibility Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result 5.3. Advice for firefighters Fire Fighting Alert Fire Brigade and tell them location and nature of hazard. May be violently or explosively reactive. Wear breathing apparatus plus protective gloves in the event of a fire. Prevent, by any means available, spillage from entering drains or water course. Consider evacuation (or protect in place). Fight fire from a safe distance, with adequate cover. If safe, switch off electrical equipment until vapour fire hazard removed. Use water delivered as a fine spray to control the fire and cool adjacent area. Avoid spraying water onto liquid pools. Do not approach containers suspected to be hot. Cool fire exposed containers with water spray from a protected location. If safe to do so, remove containers from path of fire. Fire/Explosion Hazard Liquid and vapour are highly flammable. Severe fire hazard when exposed to heat, flame and/or oxidisers. Vapour may travel a considerable distance to source of ignition. Heating may cause expansion or decomposition leading to violent rupture of containers. On combustion, may emit toxic fumes of carbon monoxide (CO). Combustion products include: carbon dioxide (CO2) other pyrolysis products typical of burning organic material. Contains low boiling substance: Closed containers may rupture due to pressure buildup under fire conditions. SECTION 6 ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures See section 8 6.2. Environmental precautions See section 12 6.3. Methods and material for containment and cleaning up Minor Spills Remove all ignition sources. Clean up all spills immediately. Avoid breathing vapours and contact with skin and eyes. Control personal contact with the substance, by using protective equipment. Contain and absorb small quantities with vermiculite or other absorbent material. Wipe up. Collect residues in a flammable waste container. Chemical Class: aromatic hydrocarbons For release onto land: recommended sorbents listed in order of priority. SORBENT TYPE RANK APPLICATION COLLECTION LIMITATIONS LAND SPILL - SMALL Major Spills Feathers - pillow 1 throw pitchfork DGC, RT cross-linked polymer - particulate 2 shovel shovel R,W,SS cross-linked polymer- pillow 2 throw pitchfork R, DGC, RT sorbent clay - particulate 3 shovel shovel R, I, P, treated clay/ treated natural organic - particulate 3 shovel shovel R, I wood fibre - pillow 4 throw pitchfork R, P, DGC, RT LAND SPILL - MEDIUM cross-linked polymer -particulate 1 blower skiploader R, W, SS Continued... Page 5 of 24 838 Total Ground Carbon Conductive Coating treated clay/ treated natural organic - particulate 2 blower skiploader R, I sorbent clay - particulate 3 blower skiploader R, I, P polypropylene - particulate 3 blower skiploader W, SS, DGC feathers - pillow 3 throw skiploader DGC, RT expanded mineral - particulate 4 blower skiploader R, I, W, P, DGC Legend DGC: Not effective where ground cover is dense R; Not reusable I: Not incinerable P: Effectiveness reduced when rainy RT:Not effective where terrain is rugged SS: Not for use within environmentally sensitive sites W: Effectiveness reduced when windy Reference: Sorbents for Liquid Hazardous Substance Cleanup and Control; R.W Melvold et al: Pollution Technology Review No. 150: Noyes Data Corporation 1988 Clear area of personnel and move upwind. Alert Fire Brigade and tell them location and nature of hazard. May be violently or explosively reactive. Wear breathing apparatus plus protective gloves. Prevent, by any means available, spillage from entering drains or water course. Consider evacuation (or protect in place). No smoking, naked lights or ignition sources. Increase ventilation. Stop leak if safe to do so. Water spray or fog may be used to disperse /absorb vapour. Contain spill with sand, earth or vermiculite. Use only spark-free shovels and explosion proof equipment. Collect recoverable product into labelled containers for recycling. Absorb remaining product with sand, earth or vermiculite. Collect solid residues and seal in labelled drums for disposal. Wash area and prevent runoff into drains. If contamination of drains or waterways occurs, advise emergency services. 6.4. Reference to other sections Personal Protective Equipment advice is contained in Section 8 of the SDS. SECTION 7 HANDLING AND STORAGE 7.1. Precautions for safe handling Safe handling Fire and explosion protection Other information Containers, even those that have been emptied, may contain explosive vapours. Do NOT cut, drill, grind, weld or perform similar operations on or near containers. Contains low boiling substance: Storage in sealed containers may result in pressure buildup causing violent rupture of containers not rated appropriately. Check for bulging containers. Vent periodically Always release caps or seals slowly to ensure slow dissipation of vapours Electrostatic discharge may be generated during pumping - this may result in fire. Ensure electrical continuity by bonding and grounding (earthing) all equipment. Restrict line velocity during pumping in order to avoid generation of electrostatic discharge (<=1 m/sec until fill pipe submerged to twice its diameter, then <= 7 m/sec). Avoid splash filling. Do NOT use compressed air for filling discharging or handling operations. Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs. Use in a well-ventilated area. Prevent concentration in hollows and sumps. DO NOT enter confined spaces until atmosphere has been checked. Avoid smoking, naked lights, heat or ignition sources. When handling, DO NOT eat, drink or smoke. Vapour may ignite on pumping or pouring due to static electricity. DO NOT use plastic buckets. Earth and secure metal containers when dispensing or pouring product. Use spark-free tools when handling. Avoid contact with incompatible materials. Keep containers securely sealed. Avoid physical damage to containers. Always wash hands with soap and water after handling. Work clothes should be laundered separately. Use good occupational work practice. Observe manufacturer's storage and handling recommendations contained within this SDS. Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions. DO NOT allow clothing wet with material to stay in contact with skin See section 5 Store in original containers in approved flame-proof area. No smoking, naked lights, heat or ignition sources. DO NOT store in pits, depressions, basements or areas where vapours may be trapped. Keep containers securely sealed. Store away from incompatible materials in a cool, dry well ventilated area. Protect containers against physical damage and check regularly for leaks. Continued... Page 6 of 24 838 Total Ground Carbon Conductive Coating Observe manufacturer's storage and handling recommendations contained within this SDS. 7.2. Conditions for safe storage, including any incompatibilities Suitable container Packing as supplied by manufacturer. Plastic containers may only be used if approved for flammable liquid. Check that containers are clearly labelled and free from leaks. For low viscosity materials (i) : Drums and jerry cans must be of the non-removable head type. (ii) : Where a can is to be used as an inner package, the can must have a screwed enclosure. For materials with a viscosity of at least 2680 cSt. (23 deg. C) For manufactured product having a viscosity of at least 250 cSt. (23 deg. C) Manufactured product that requires stirring before use and having a viscosity of at least 20 cSt (25 deg. C): (i) Removable head packaging; (ii) Cans with friction closures and (iii) low pressure tubes and cartridges may be used. Where combination packages are used, and the inner packages are of glass, there must be sufficient inert cushioning material in contact with inner and outer packages In addition, where inner packagings are glass and contain liquids of packing group I there must be sufficient inert absorbent to absorb any spillage, unless the outer packaging is a close fitting moulded plastic box and the substances are not incompatible with the plastic. Storage incompatibility Heptanones: react violently with strong oxidisers, aldehydes, nitric acid, perchloric acid form a variety of unstable peroxides following reaction with hydrogen peroxide are incompatible with aliphatic amines, aldehydes, strong bases Toluene: reacts violently with strong oxidisers, bromine, bromine trifluoride, chlorine, hydrochloric acid/ sulfuric acid mixture, 1,3-dichloro-5,5-dimethyl2,4-imidazolidindione, dinitrogen tetraoxide, fluorine, concentrated nitric acid, nitrogen dioxide, silver chloride, sulfur dichloride, uranium fluoride, vinyl acetate forms explosive mixtures with strong acids, strong oxidisers, silver perchlorate, tetranitromethane is incompatible with bis-toluenediazo oxide attacks some plastics, rubber and coatings may generate electrostatic charges, due to low conductivity, on flow or agitation. Avoid oxidising agents, acids, acid chlorides, acid anhydrides, chloroformates. For alkyl aromatics: The alkyl side chain of aromatic rings can undergo oxidation by several mechanisms. The most common and dominant one is the attack by oxidation at benzylic carbon as the intermediate formed is stabilised by resonance structure of the ring. Following reaction with oxygen and under the influence of sunlight, a hydroperoxide at the alpha-position to the aromatic ring, is the primary oxidation product formed (provided a hydrogen atom is initially available at this position) - this product is often short-lived but may be stable dependent on the nature of the aromatic substitution; a secondary C-H bond is more easily attacked than a primary C-H bond whilst a tertiary C-H bond is even more susceptible to attack by oxygen Monoalkylbenzenes may subsequently form monocarboxylic acids; alkyl naphthalenes mainly produce the corresponding naphthalene carboxylic acids. Oxidation in the presence of transition metal salts not only accelerates but also selectively decomposes the hydroperoxides. Hock-rearrangement by the influence of strong acids converts the hydroperoxides to hemiacetals. Peresters formed from the hydroperoxides undergo Criegee rearrangement easily. Alkali metals accelerate the oxidation while CO2 as co-oxidant enhances the selectivity. Microwave conditions give improved yields of the oxidation products. Photo-oxidation products may occur following reaction with hydroxyl radicals and NOx - these may be components of photochemical smogs. Oxidation of Alkylaromatics: T.S.S Rao and Shubhra Awasthi: E-Journal of Chemistry Vol 4, No. 1, pp 1-13 January 2007 Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic rings and strong oxidising agents. Aromatics can react exothermically with bases and with diazo compounds. 7.3. Specific end use(s) See section 1.2 SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION 8.1. Control parameters Ingredient toluene isobutyl acetate DNELs Exposure Pattern Worker Dermal 384 mg/kg bw/day (Systemic, Chronic) Inhalation 192 mg/m³ (Systemic, Chronic) Inhalation 192 mg/m³ (Local, Chronic) Inhalation 384 mg/m³ (Systemic, Acute) Inhalation 384 mg/m³ (Local, Acute) Dermal 226 mg/kg bw/day (Systemic, Chronic) * Inhalation 56.5 mg/m³ (Systemic, Chronic) * Oral 8.13 mg/kg bw/day (Systemic, Chronic) * Inhalation 56.5 mg/m³ (Local, Chronic) * Inhalation 226 mg/m³ (Systemic, Acute) * Inhalation 226 mg/m³ (Local, Acute) * Dermal 10 mg/kg bw/day (Systemic, Chronic) Inhalation 300 mg/m³ (Systemic, Chronic) Inhalation 300 mg/m³ (Local, Chronic) Dermal 10 mg/kg bw/day (Systemic, Acute) Inhalation 600 mg/m³ (Systemic, Acute) Inhalation 600 mg/m³ (Local, Acute) Dermal 5 mg/kg bw/day (Systemic, Chronic) * Inhalation 35.7 mg/m³ (Systemic, Chronic) * Oral 5 mg/kg bw/day (Systemic, Chronic) * Inhalation 35.7 mg/m³ (Local, Chronic) * Dermal 5 mg/kg bw/day (Systemic, Acute) * Inhalation 300 mg/m³ (Systemic, Acute) * Oral 5 mg/kg bw/day (Systemic, Acute) * PNECs Compartment 16.39 mg/kg sediment dw (Sediment (Marine)) 0.0877 mg/kg sediment dw (Sediment (Marine)) Continued... Page 7 of 24 838 Total Ground Carbon Conductive Coating amyl methyl ketone acetone ethanol ethyl acetate propylene glycol monomethyl ether - mixture of isomers * Values for General Population Inhalation 300 mg/m³ (Local, Acute) * Dermal 54.27 mg/kg bw/day (Systemic, Chronic) Inhalation 394.25 mg/m³ (Systemic, Chronic) Inhalation 1 516 mg/m³ (Systemic, Acute) Dermal 23.32 mg/kg bw/day (Systemic, Chronic) * Inhalation 84.31 mg/m³ (Systemic, Chronic) * Oral 23.32 mg/kg bw/day (Systemic, Chronic) * Dermal 186 mg/kg bw/day (Systemic, Chronic) Inhalation 1 210 mg/m³ (Systemic, Chronic) Inhalation 2 420 mg/m³ (Local, Acute) Dermal 62 mg/kg bw/day (Systemic, Chronic) * Inhalation 200 mg/m³ (Systemic, Chronic) * Oral 62 mg/kg bw/day (Systemic, Chronic) * Dermal 343 mg/kg bw/day (Systemic, Chronic) Inhalation 950 mg/m³ (Systemic, Chronic) Dermal 206 mg/kg bw/day (Systemic, Chronic) * Inhalation 114 mg/m³ (Systemic, Chronic) * Oral 87 mg/kg bw/day (Systemic, Chronic) * Dermal 63 mg/kg bw/day (Systemic, Chronic) Inhalation 734 mg/m³ (Systemic, Chronic) Inhalation 734 mg/m³ (Local, Chronic) Inhalation 1 468 mg/m³ (Systemic, Acute) Inhalation 1 468 mg/m³ (Local, Acute) Dermal 37 mg/kg bw/day (Systemic, Chronic) * Inhalation 367 mg/m³ (Systemic, Chronic) * Oral 4.5 mg/kg bw/day (Systemic, Chronic) * Inhalation 367 mg/m³ (Local, Chronic) * Inhalation 734 mg/m³ (Systemic, Acute) * Inhalation 734 mg/m³ (Local, Acute) * Dermal 183 mg/kg bw/day (Systemic, Chronic) Inhalation 275 mg/m³ (Systemic, Chronic) Inhalation 553.5 mg/m³ (Systemic, Acute) Inhalation 550 mg/m³ (Local, Acute) Dermal 78 mg/kg bw/day (Systemic, Chronic) * Inhalation 33 mg/m³ (Systemic, Chronic) * Oral 33 mg/kg bw/day (Systemic, Chronic) * Inhalation 33 mg/m³ (Local, Chronic) * Not Available Not Available 2.9 (Sediment (Marine)) 0.72 g/kg food (Oral) 0.125 mg/kg sediment dw (Sediment (Marine)) 0.2 g/kg food (Oral) 0.329 mg/kg sediment dw (Sediment (Marine)) OCCUPATIONAL EXPOSURE LIMITS (OEL) INGREDIENT DATA Source Ingredient EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) toluene UK Workplace Exposure Limits (WELs) toluene UK Workplace Exposure Limits (WELs) isobutyl acetate EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) amyl methyl ketone UK Workplace Exposure Limits (WELs) amyl methyl ketone EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) acetone UK Workplace Exposure Limits (WELs) acetone UK Workplace Exposure Limits (WELs) ethanol EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) ethyl acetate UK Workplace Exposure Limits (WELs) ethyl acetate EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) propylene glycol monomethyl ether mixture of isomers EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) propylene glycol monomethyl ether mixture of isomers UK Workplace Exposure Limits (WELs) propylene glycol monomethyl ether mixture of isomers UK Workplace Exposure Limits (WELs) propylene glycol monomethyl ether mixture of isomers Material name Toluene Toluene Isobutyl acetate Heptan-2-one Heptan-2-one Acetone Acetone Ethanol Ethyl acetate Ethyl acetate 1-Methoxypropyl2-acetate TWA 50 ppm / 192 mg/m3 50 ppm / 191 mg/m3 150 ppm / 724 mg/m3 50 ppm / 238 mg/m3 50 ppm / 237 mg/m3 500 ppm / 1210 mg/m3 500 ppm / 1210 mg/m3 1000 ppm / 1920 mg/m3 200 ppm / 734 mg/m3 200 ppm / 734 mg/m3 50 ppm / 275 mg/m3 STEL 384 mg/m3 / 100 ppm 384 mg/m3 / 100 ppm 903 mg/m3 / 187 ppm 475 mg/m3 / 100 ppm 475 mg/m3 / 100 ppm Not Available 3620 mg/m3 / 1500 ppm Not Available 1 468 mg/m3 / 400 ppm 1468 mg/m3 / 400 ppm 550 mg/m3 / 100 ppm Peak Not Available Not Available Not Available Not Available Not Available Not Available Not Available Not Available Not Available Not Available Not Available 1-Methoxypropan-2-ol 1-Methoxypropan-2-ol 1-Methoxypropyl acetate 100 ppm / 375 mg/m3 100 ppm / 375 mg/m3 50 ppm / 274 mg/m3 568 mg/m3 / 150 ppm 560 mg/m3 / 150 ppm 548 mg/m3 / 100 ppm Not Available Not Available Not Available Notes Skin Sk Not Available Skin Sk Not Available Not Available Not Available Not Available Not Available Skin Skin Sk Sk Continued... Page 8 of 24 838 Total Ground Carbon Conductive Coating EMERGENCY LIMITS Ingredient toluene isobutyl acetate amyl methyl ketone acetone ethanol ethyl acetate propylene glycol monomethyl ether - mixture of isomers propylene glycol monomethyl ether - mixture of isomers Material name Toluene Isobutyl acetate Methyl n-amyl ketone Acetone Ethyl alcohol; (Ethanol) Ethyl acetate Propylene glycol monomethyl ether; (Ucar Triol HG-170) Propylene glycol monomethyl ether acetate, alpha-isomer; (1-Methoxypropyl-2-acetate) TEEL-1 Not Available 450 ppm 150 ppm Not Available Not Available 1,200 ppm 100 ppm TEEL-2 Not Available 1300 ppm 670 ppm Not Available Not Available 1,700 ppm 160 ppm TEEL-3 Not Available 7500 ppm 4000 ppm Not Available 15000 ppm 10000 ppm 660 ppm Not Available Not Available Not Available Ingredient toluene isobutyl acetate amyl methyl ketone acetone ethanol ethyl acetate propylene glycol monomethyl ether - mixture of isomers Original IDLH 500 ppm 1,300 ppm 800 ppm 2,500 ppm 3,300 ppm 2,000 ppm Not Available Revised IDLH Not Available Not Available Not Available Not Available Not Available Not Available Not Available MATERIAL DATA for isobutyl acetate: Odour Threshold Value: 0.40-0.44 ppm (recognition) The TLV-TWA is identical with that of n-butyl acetate and is thought to minimise the potential for ocular and upper respiratory tract irritation. IFRA Prohibited Fragrance Substance The International Fragrance Association (IFRA) Standards form the basis for the globally accepted and recognized risk management system for the safe use of fragrance ingredients and are part of the IFRA Code of Practice. This is the self-regulating system of the industry, based on risk assessments carried out by an independent Expert Panel For ethanol: Odour Threshold Value: 49-716 ppm (detection), 101 ppm (recognition) Eye and respiratory tract irritation do not appear to occur at exposure levels of less than 5000 ppm and the TLV-TWA is thought to provide an adequate margin of safety against such effects. Experiments in man show that inhalation of 1000 ppm caused slight symptoms of poisoning and 5000 ppm caused strong stupor and morbid sleepiness. Subjects exposed to 5000 ppm to 10000 ppm experienced smarting of the eyes and nose and coughing. Symptoms disappeared within minutes. Inhalation also causes local irritating effects to the eyes and upper respiratory tract, headaches, sensation of heat intraocular tension, stupor, fatigue and a need to sleep. At 15000 ppm there was continuous lachrymation and coughing. For ethyl acetate: Odour Threshold Value: 6.4-50 ppm (detection), 13.3-75 ppm (recognition) The TLV-TWA provides a significant margin of safety from the standpoint of adverse health effects. Unacclimated subjects found the odour objectionably strong at 200 ppm. Mild nose, eye and throat irritation was experienced at 400 ppm. Workers exposed regularly at concentrations ranging from 375 ppm to 1500 ppm for several months showed no unusual signs or symptoms. Odour Safety Factor(OSF) OSF=51 (ETHYL ACETATE) Odour Threshold Value: 3.6 ppm (detection), 699 ppm (recognition) Saturation vapour concentration: 237000 ppm @ 20 C NOTE: Detector tubes measuring in excess of 40 ppm, are available. Exposure at or below the recommended TLV-TWA is thought to protect the worker against mild irritation associated with brief exposures and the bioaccumulation, chronic irritation of the respiratory tract and headaches associated with long-term acetone exposures. The NIOSH REL-TWA is substantially lower and has taken into account slight irritation experienced by volunteer subjects at 300 ppm. Mild irritation to acclimatised workers begins at about 750 ppm - unacclimatised subjects will experience irritation at about 350-500 ppm but acclimatisation can occur rapidly. Disagreement between the peak bodies is based largely on the view by ACGIH that widespread use of acetone, without evidence of significant adverse health effects at higher concentrations, allows acceptance of a higher limit. Half-life of acetone in blood is 3 hours which means that no adjustment for shift-length has to be made with reference to the standard 8 hour/day, 40 hours per week because body clearance occurs within any shift with low potential for accumulation. A STEL has been established to prevent excursions of acetone vapours that could cause depression of the central nervous system. Odour Safety Factor(OSF) OSF=38 (ACETONE) for propylene glycol monomethyl ether (PGME) Odour Threshold: 10 ppm. The TLV-TWA is protective against discomfort caused by odour, against eye and skin irritation, and chronic effects (including possible liver and kidney damage). Individuals exposed to 100 ppm reported a transient unpleasant odour with slight eye irritation after about 1 or 2 hours. At 300 ppm, mild irritation of the eyes and nose developed within 5 minutes; some individuals found the irritation hardly bearable after about an hour. A concentration of 750 ppm was highly irritating. Signs of central nervous system depression developed at 1000 ppm. Neurological, clinical chemical and general medical examinations showed no other conspicuous toxicity. Concentrations of the beta-isomer, 2-methoxy-1-propyl acetate are low in commercial grades of PGME and teratogenic effects associated with this isomer are expected to be absent. Odour Safety Factor(OSF) OSF=10 (propylene glycol monomethyl ether) For toluene: Odour Threshold Value: 0.16-6.7 (detection), 1.9-69 (recognition) NOTE: Detector tubes measuring in excess of 5 ppm, are available. High concentrations of toluene in the air produce depression of the central nervous system (CNS) in humans. Intentional toluene exposure (glue-sniffing) at maternally-intoxicating concentration has also produced birth defects. Foetotoxicity appears at levels associated with CNS narcosis and probably occurs only in those with chronic toluene-induced kidney failure. Exposure at or below the recommended TLV-TWA is thought to prevent transient headache and irritation, to provide a measure of safety for possible disturbances to human reproduction, the prevention of reductions in cognitive responses reported amongst humans inhaling greater than 40 ppm, and the significant risks of hepatotoxic, behavioural and nervous system effects (including impaired reaction time and incoordination). Although toluene/ethanol interactions are well recognised, the degree of protection afforded by the TLV-TWA among drinkers is not known. Odour Safety Factor(OSF) OSF=17 (TOLUENE) Continued... Page 9 of 24 838 Total Ground Carbon Conductive Coating For amyl methyl ketone: Odour Threshold Value: 0.18 ppm (detection) The TLV-TWA is well below the highest level of vapour (1025 ppm) reported to be associated with adverse effects in animals including dermal irritation. Odour Safety Factor (OSF) OSF=1.4E2 (2-HEPTANONE) 8.2. Exposure controls Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well-designed engineering controls can be highly effective in protecting workers and will typically be independent of worker interactions to provide this high level of protection. The basic types of engineering controls are: Process controls which involve changing the way a job activity or process is done to reduce the risk. Enclosure and/or isolation of emission source which keeps a selected hazard 'physically' away from the worker and ventilation that strategically 'adds' and 'removes' air in the work environment. Ventilation can remove or dilute an air contaminant if designed properly. The design of a ventilation system must match the particular process and chemical or contaminant in use. Employers may need to use multiple types of controls to prevent employee overexposure. For flammable liquids and flammable gases, local exhaust ventilation or a process enclosure ventilation system may be required. Ventilation equipment should be explosion-resistant. Air contaminants generated in the workplace possess varying 'escape' velocities which, in turn, determine the 'capture velocities' of fresh circulating air required to effectively remove the contaminant. 8.2.1. Appropriate engineering controls Type of Contaminant: solvent, vapours, degreasing etc., evaporating from tank (in still air). aerosols, fumes from pouring operations, intermittent container filling, low speed conveyer transfers, welding, spray drift, plating acid fumes, pickling (released at low velocity into zone of active generation) direct spray, spray painting in shallow booths, drum filling, conveyer loading, crusher dusts, gas discharge (active generation into zone of rapid air motion) Air Speed: 0.25-0.5 m/s (50-100 f/min.) 0.5-1 m/s (100-200 f/min.) 1-2.5 m/s (200-500 f/min.) Within each range the appropriate value depends on: Lower end of the range Upper end of the range 1: Room air currents minimal or favourable to capture 1: Disturbing room air currents 2: Contaminants of low toxicity or of nuisance value only. 2: Contaminants of high toxicity 3: Intermittent, low production. 3: High production, heavy use 4: Large hood or large air mass in motion 4: Small hood-local control only Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example, should be a minimum of 1-2 m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from the extraction point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used. 8.2.2. Personal protection Eye and face protection Skin protection Hands/feet protection Safety glasses with side shields. Chemical goggles. Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of lenses or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. Medical and first-aid personnel should be trained in their removal and suitable equipment should be readily available. In the event of chemical exposure, begin eye irrigation immediately and remove contact lens as soon as practicable. Lens should be removed at the first signs of eye redness or irritation - lens should be removed in a clean environment only after workers have washed hands thoroughly. [CDC NIOSH Current Intelligence Bulletin 59], [AS/NZS 1336 or national equivalent] See Hand protection below Wear chemical protective gloves, e.g. PVC. Wear safety footwear or safety gumboots, e.g. Rubber The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from manufacturer to manufacturer. Where the chemical is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. The exact break through time for substances has to be obtained from the manufacturer of the protective gloves and.has to be observed when making a final choice. Personal hygiene is a key element of effective hand care. Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of a non-perfumed moisturiser is recommended. Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include: · frequency and duration of contact, · chemical resistance of glove material, · glove thickness and · dexterity Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739, AS/NZS 2161.1 or national equivalent). · When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time Continued... Page 10 of 24 838 Total Ground Carbon Conductive Coating Body protection Other protection greater than 240 minutes according to EN 374, AS/NZS 2161.10.1 or national equivalent) is recommended. · When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374, AS/NZS 2161.10.1 or national equivalent) is recommended. · Some glove polymer types are less affected by movement and this should be taken into account when considering gloves for long-term use. · Contaminated gloves should be replaced. As defined in ASTM F-739-96 in any application, gloves are rated as: · Excellent when breakthrough time > 480 min · Good when breakthrough time > 20 min · Fair when breakthrough time < 20 min · Poor when glove material degrades For general applications, gloves with a thickness typically greater than 0.35 mm, are recommended. It should be emphasised that glove thickness is not necessarily a good predictor of glove resistance to a specific chemical, as the permeation efficiency of the glove will be dependent on the exact composition of the glove material. Therefore, glove selection should also be based on consideration of the task requirements and knowledge of breakthrough times. Glove thickness may also vary depending on the glove manufacturer, the glove type and the glove model. Therefore, the manufacturers' technical data should always be taken into account to ensure selection of the most appropriate glove for the task. Note: Depending on the activity being conducted, gloves of varying thickness may be required for specific tasks. For example: · Thinner gloves (down to 0.1 mm or less) may be required where a high degree of manual dexterity is needed. However, these gloves are only likely to give short duration protection and would normally be just for single use applications, then disposed of. · Thicker gloves (up to 3 mm or more) may be required where there is a mechanical (as well as a chemical) risk i.e. where there is abrasion or puncture potential Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of a non-perfumed moisturiser is recommended. See Other protection below Overalls. PVC Apron. PVC protective suit may be required if exposure severe. Eyewash unit. Ensure there is ready access to a safety shower. Some plastic personal protective equipment (PPE) (e.g. gloves, aprons, overshoes) are not recommended as they may produce static electricity. For large scale or continuous use wear tight-weave non-static clothing (no metallic fasteners, cuffs or pockets). Non sparking safety or conductive footwear should be considered. Conductive footwear describes a boot or shoe with a sole made from a conductive compound chemically bound to the bottom components, for permanent control to electrically ground the foot an shall dissipate static electricity from the body to reduce the possibility of ignition of volatile compounds. Electrical resistance must range between 0 to 500,000 ohms. Conductive shoes should be stored in lockers close to the room in which they are worn. Personnel who have been issued conductive footwear should not wear them from their place of work to their homes and return. Recommended material(s) GLOVE SELECTION INDEX Glove selection is based on a modified presentation of the: 'Forsberg Clothing Performance Index'. The effect(s) of the following substance(s) are taken into account in the computergenerated selection: 838 Total Ground Carbon Conductive Coating Material CPI PE/EVAL/PE A BUTYL C BUTYL/NEOPRENE C CPE C HYPALON C NATURAL RUBBER C NATURAL+NEOPRENE C NEOPRENE C NEOPRENE/NATURAL C NITRILE C NITRILE+PVC C PVA C PVC C PVDC/PE/PVDC C SARANEX-23 C SARANEX-23 2-PLY C TEFLON C VITON C VITON/CHLOROBUTYL C VITON/NEOPRENE C * CPI - Chemwatch Performance Index A: Best Selection B: Satisfactory; may degrade after 4 hours continuous immersion C: Poor to Dangerous Choice for other than short term immersion NOTE: As a series of factors will influence the actual performance of the glove, a final selection must be based on detailed observation. - Respiratory protection Type AX Filter of sufficient capacity. (AS/NZS 1716 & 1715, EN 143:2000 & 149:2001, ANSI Z88 or national equivalent) Where the concentration of gas/particulates in the breathing zone, approaches or exceeds the 'Exposure Standard' (or ES), respiratory protection is required. Degree of protection varies with both face-piece and Class of filter; the nature of protection varies with Type of filter. Required Minimum Protection Factor up to 5 x ES up to 25 x ES up to 50 x ES 50+ x ES Half-Face Respirator Full-Face Respirator AX-AUS / Class 1- Air-line* - AX-2 AX-3 Air-line** Powered Air Respirator AX-PAPR-AUS / Class 1 AX-PAPR-2 - ^ - Full-face A(All classes) = Organic vapours, B AUS or B1 = Acid gasses, B2 = Acid gas or hydrogen cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E = Sulfur dioxide(SO2), G = Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = Methyl bromide, AX = Low boiling point organic compounds(below 65 degC) Cartridge respirators should never be used for emergency ingress or in areas of unknown vapour concentrations or oxygen content. The wearer must be warned to leave the contaminated area immediately on detecting any odours through the respirator. The odour may indicate that the mask is not functioning properly, that the vapour concentration is too high, or that the mask is not properly fitted. Because of these limitations, only restricted use of cartridge respirators is considered appropriate. Cartridge performance is affected by humidity. Cartridges should be changed after 2 hr of continuous use unless it is determined that the humidity is less than 75%, in which case, cartridges can be used for 4 hr. Used cartridges should be discarded daily, regardless of the length of time used Continued... Page 11 of 24 838 Total Ground Carbon Conductive Coating * Where the glove is to be used on a short term, casual or infrequent basis, factors such as 'feel' or convenience (e.g. disposability), may dictate a choice of gloves which might otherwise be unsuitable following long-term or frequent use. A qualified practitioner should be consulted. 8.2.3. Environmental exposure controls See section 12 SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES 9.1. Information on basic physical and chemical properties Appearance Liquid Physical state Liquid Odour Not Available Odour threshold pH (as supplied) Melting point / freezing point (°C) Initial boiling point and boiling range (°C) Flash point (°C) Evaporation rate Flammability Not Available Not Available Not Available >56 -17 Not Available HIGHLY FLAMMABLE. Upper Explosive Limit (%) 12 Lower Explosive Limit (%) Vapour pressure (kPa) Solubility in water Vapour density (Air = 1) 2 Not Available Partly miscible >1.6 9.2. Other information Not Available SECTION 10 STABILITY AND REACTIVITY 10.1.Reactivity See section 7.2 10.2. Chemical stability 10.3. Possibility of hazardous reactions 10.4. Conditions to avoid Unstable in the presence of incompatible materials. Product is considered stable. Hazardous polymerisation will not occur. See section 7.2 See section 7.2 10.5. Incompatible materials 10.6. Hazardous decomposition products See section 7.2 See section 5.3 SECTION 11 TOXICOLOGICAL INFORMATION 11.1. Information on toxicological effects Relative density (Water = 1) Partition coefficient n-octanol / water Auto-ignition temperature (°C) Decomposition temperature 0.90 Not Available >315 Not Available Viscosity (cSt) >34 Molecular weight (g/mol) Not Available Taste Explosive properties Oxidising properties Surface Tension (dyn/cm or mN/m) Volatile Component (%vol) Gas group pH as a solution (1%) VOC g/L Not Available Not Available Not Available Not Available Not Available Not Available Not Available Not Available Inhaled Strong evidence exists that exposure to the material may produce very serious irreversible damage (other than carcinogenesis, mutagenesis and teratogenesis) following a single exposure by inhalation. The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified by EC Directives using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by narcosis, reduced alertness, loss of reflexes, lack of coordination and vertigo. The most common signs of inhalation overexposure to ethanol, in animals, include ataxia, incoordination and drowsiness for those surviving narcosis. The narcotic dose for rats, after 2 hours of exposure, is 19260 ppm. Acute effects from inhalation of high concentrations of vapour are pulmonary irritation, including coughing, with nausea; central nervous system depression - characterised by headache and dizziness, increased reaction time, fatigue and loss of co-ordination Central nervous system (CNS) depression may include nonspecific discomfort, symptoms of giddiness, headache, dizziness, nausea, anaesthetic effects, slowed reaction time, slurred speech and may progress to unconsciousness. Serious poisonings may result in respiratory depression and may be fatal. Continued... Page 12 of 24 838 Total Ground Carbon Conductive Coating The acute toxicity of inhaled alkylbenzenes is best described by central nervous system depression. As a rule, these compounds may also act as general anaesthetics. Systemic poisoning produced by general anaesthesia is characterised by lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting and sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness and respiratory depression and arrest. Cardiac arrest may result from cardiovascular collapse. Bradycardia, and hypotension may also be produced. Inhaled alkylbenzene vapours cause death in animals at air levels that are relatively similar (typically LC50s are in the range 5000 -8000 ppm for 4 to 8 hour exposures). It is likely that acute inhalation exposure to alkylbenzenes resembles that to general anaesthetics. Alkylbenzenes are not generally toxic other than at high levels of exposure. This may be because their metabolites have a low order of toxicity and are easily excreted. There is little or no evidence to suggest that metabolic pathways can become saturated leading to spillover to alternate pathways. Nor is there evidence that toxic reactive intermediates, which may produce subsequent toxic or mutagenic effects, are formed Material is highly volatile and may quickly form a concentrated atmosphere in confined or unventilated areas. The vapour may displace and replace air in breathing zone, acting as a simple asphyxiant. This may happen with little warning of overexposure. The use of a quantity of material in an unventilated or confined space may result in increased exposure and an irritating atmosphere developing. Before starting consider control of exposure by mechanical ventilation. Inhalation of vapours or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to the health of the individual. Strong evidence exists that exposure to the material may produce very serious irreversible damage (other than carcinogenesis, mutagenesis and teratogenesis) following a single exposure by swallowing. Swallowing of the liquid may cause aspiration of vomit into the lungs with the risk of haemorrhaging, pulmonary oedema, progressing to chemical pneumonitis; serious consequences may result. Signs and symptoms of chemical (aspiration) pneumonitis may include coughing, gasping, choking, burning of the mouth, difficult breathing, and bluish coloured skin (cyanosis). Ingestion of ethanol may produce nausea, vomiting, gastrointestinal bleeding, abdominal pain and diarrhoea. Systemic effects: Ingestion Blood concentration: <1.5 g/l 1.5-3.0 g/l 3-5 g/l Effects: Mild: Impaired visual acuity, coordination and reaction time, emotional lability Moderate: Slurred speech, confusion, ataxia, emotional lability, perceptual and sensation disturbances possible blackout spells, and incoordination with impaired objective performance in standardised tests. Possible diplopia, flushing, tachycardia, sweating and incontinence. Bradypnoea may occur early and tachypnoea may develop in cases of metabollic acidosis, hypoglycaemia and hypokalaemia. CNS depression may progress to coma. Severe: Cold clammy skin, hypothermia and hypotension. Atrial fibrillation and atrioventricular block have been reported. Respiratory depression may occur, respiratory failure may follow serious intoxication, aspiration of vomitus may result in pneumonitis and pulmonary oedema. Convulsions due to severe hypoglycaemia may also occur Acute hepatitis may develop. The material has NOT been classified by EC Directives or other classification systems as 'harmful by ingestion'. This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern. Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. Skin Contact Strong evidence exists that exposure to the material may produce very serious irreversible damage (other than carcinogenesis, mutagenesis and teratogenesis) following a single exposure by skin contact. The material may accentuate any pre-existing dermatitis condition Skin contact is not thought to have harmful health effects (as classified under EC Directives); the material may still produce health damage following entry through wounds, lesions or abrasions. Open cuts, abraded or irritated skin should not be exposed to this material Entry into the blood-stream through, for example, cuts, abrasions, puncture wounds or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. Skin contact with the material may damage the health of the individual; systemic effects may result following absorption. The material produces moderate skin irritation; evidence exists, or practical experience predicts, that the material either produces moderate inflammation of the skin in a substantial number of individuals following direct contact, and/or produces significant, but moderate, inflammation when applied to the healthy intact skin of animals (for up to four hours), such inflammation being present twenty-four hours or more after the end of the exposure period. Skin irritation may also be present after prolonged or repeated exposure; this may result in a form of contact dermatitis (nonallergic). The dermatitis is often characterised by skin redness (erythema) and swelling (oedema) which may progress to blistering (vesiculation), scaling and thickening of the epidermis. At the microscopic level there may be intercellular oedema of the spongy layer of the skin (spongiosis) and intracellular oedema of the epidermis. Direct contact of the eye with ethanol may cause immediate stinging and burning with reflex closure of the lid and tearing, transient injury of the corneal epithelium and hyperaemia of the conjunctiva. Foreign-body type discomfort may persist for up to 2 days but healing is usually spontaneous and complete. Evidence exists, or practical experience predicts, that the material may cause severe eye irritation in a substantial number of individuals and/or may produce significant ocular lesions which are present twenty-four hours or more after instillation into the eye(s) of experimental animals. Eye Eye contact may cause significant inflammation with pain. Corneal injury may occur; permanent impairment of vision may result unless treatment is prompt and adequate. Repeated or prolonged exposure to irritants may cause inflammation characterised by a temporary redness (similar to windburn) of the conjunctiva (conjunctivitis); temporary impairment of vision and/or other transient eye damage/ulceration may occur. The liquid produces a high level of eye discomfort and is capable of causing pain and severe conjunctivitis. Corneal injury may develop, with possible permanent impairment of vision, if not promptly and adequately treated. Continued... Page 13 of 24 838 Total Ground Carbon Conductive Coating Repeated or long-term occupational exposure is likely to produce cumulative health effects involving organs or biochemical systems. On the basis, primarily, of animal experiments, concern has been expressed that the material may produce carcinogenic or mutagenic effects; in respect of the available information, however, there presently exists inadequate data for making a satisfactory assessment. There is sufficient evidence to provide a strong presumption that human exposure to the material may result in the development of heritable genetic damage, generally on the basis of - appropriate animal studies, - other relevant information There is sufficient evidence to provide a strong presumption that human exposure to the material may result in impaired fertility on the basis of: clear evidence in animal studies of impaired fertility in the absence of toxic effects, or evidence of impaired fertility occurring at around the same dose levels as other toxic effects but which is not a secondary non-specific consequence of other toxic effects. There is sufficient evidence to provide a strong presumption that human exposure to the material may result in developmental toxicity, generally on the basis of: - clear results in appropriate animal studies where effects have been observed in the absence of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not secondary non-specific consequences of the other toxic effects. Chronic Exposure to the material may cause concerns for humans owing to possible developmental toxic effects, generally on the basis that results in appropriate animal studies provide strong suspicion of developmental toxicity in the absence of signs of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not a secondary non-specific consequence of other toxic effects. Long-term exposure to ethanol may result in progressive liver damage with fibrosis or may exacerbate liver injury caused by other agents. Repeated ingestion of ethanol by pregnant women may adversely affect the central nervous system of the developing foetus, producing effects collectively described as foetal alcohol syndrome. These include mental and physical retardation, learning disturbances, motor and language deficiency, behavioural disorders and reduced head size. Consumption of ethanol (in alcoholic beverages) may be linked to the development of Type I hypersensitivities in a small number of individuals. Symptoms, which may appear immediately after consumption, include conjunctivitis, angioedema, dyspnoea, and urticarial rashes. The causative agent may be acetic acid, a metabolite (1). (1) Boehncke W.H., & H.Gall, Clinical & Experimental Allergy, 26, 1089-1091, 1996 Chronic toluene habituation occurs following intentional abuse (glue sniffing) or from occupational exposure. Ataxia, incoordination and tremors of the hands and feet (as a consequence of diffuse cerebral atrophy), headache, abnormal speech, transient memory loss, convulsions, coma, drowsiness, reduced colour perception, frank blindness, nystagmus (rapid, involuntary eye-movements), hearing loss leading to deafness and mild dementia have all been associated with chronic abuse. Peripheral nerve damage, encephalopathy, giant axonopathy electrolyte disturbances in the cerebrospinal fluid and abnormal computer tomographic (CT scans) are common amongst toluene addicts. Although toluene abuse has been linked with kidney disease, this does not commonly appear in cases of occupational toluene exposures. Cardiac and haematological toxicity are however associated with chronic toluene exposures. Cardiac arrhythmia, multifocal and premature ventricular contractions and supraventricular tachycardia are present in 20% of patients who abused toluene-containing paints. Previous suggestions that chronic toluene inhalation produced human peripheral neuropathy have been discounted. However central nervous system (CNS) depression is well documented where blood toluene exceeds 2.2 mg%. Toluene abusers can achieve transient circulating concentrations of 6.5 %. Amongst workers exposed for a median time of 29 years, to toluene, no subacute effects on neurasthenic complaints and psychometric test results could be established. The prenatal toxicity of very high toluene concentrations has been documented for several animal species and man. Malformations indicative of specific teratogenicity have not generally been found. Neonatal toxicity, described in the literature, takes the form of embryo death or delayed foetal growth and delayed skeletal system development. Permanent damage of children has been seen only when mothers have suffered from chronic intoxication as a result of 'sniffing'. 838 Total Ground Carbon Conductive Coating TOXICITY Not Available IRRITATION Not Available toluene TOXICITY dermal (rat) LD50: >2000 mg/kg[1] Inhalation (rat) LC50: 49 mg/l/4H[2] Oral (rat) LD50: 636 mg/kg[2] IRRITATION Eye (rabbit): 2mg/24h - SEVERE Eye (rabbit):0.87 mg - mild Eye (rabbit):100 mg/30sec - mild Eye: adverse effect observed (irritating)[1] Skin (rabbit):20 mg/24h-moderate Skin (rabbit):500 mg - moderate Skin: adverse effect observed (irritating)[1] Skin: no adverse effect observed (not irritating)[1] isobutyl acetate TOXICITY Dermal (rabbit) LD50: >5000 mg/kg[2] Oral (rat) LD50: 13400 mg/kg[2] IRRITATION Skin(rabbit): 500 mg open mild amyl methyl ketone TOXICITY dermal (rat) LD50: >2000 mg/kg[1] Inhalation (rat) LC50: 3995.436 mg/l/4h[2] Oral (rat) LD50: 1600 mg/kg[2] IRRITATION Eye: adverse effect observed (irritating)[1] Skin (rabbit): 14 mg/24h Mild Skin (rabbit): Primary Irritant Skin: adverse effect observed (irritating)[1] Skin: no adverse effect observed (not irritating)[1] acetone TOXICITY IRRITATION Continued... Page 14 of 24 838 Total Ground Carbon Conductive Coating Dermal (rabbit) LD50: =20 mg/kg[2] Inhalation (rat) LC50: 100.2 mg/l/8hr[2] Oral (rat) LD50: 1800-7300 mg/kg[2] Eye (human): 500 ppm - irritant Eye (rabbit): 20mg/24hr -moderate Eye (rabbit): 3.95 mg - SEVERE Eye: adverse effect observed (irritating)[1] Skin (rabbit): 500 mg/24hr - mild Skin (rabbit):395mg (open) - mild Skin: no adverse effect observed (not irritating)[1] ethanol TOXICITY Inhalation (rat) LC50: 124.7 mg/l/4H[2] Oral (rat) LD50: =1501 mg/kg[2] IRRITATION Eye (rabbit): 500 mg SEVERE Eye (rabbit):100mg/24hr-moderate Eye: adverse effect observed (irritating)[1] Skin (rabbit):20 mg/24hr-moderate Skin (rabbit):400 mg (open)-mild Skin: no adverse effect observed (not irritating)[1] ethyl acetate TOXICITY Dermal (rabbit) LD50: >18000 mg/kg[2] Inhalation (mouse) LC50: 22.5 mg/l/2H[2] Oral (rat) LD50: 5620 mg/kg[2] IRRITATION Eye (human): 400 ppm Eye: no adverse effect observed (not irritating)[1] Skin: no adverse effect observed (not irritating)[1] propylene glycol monomethyl ether - mixture of isomers TOXICITY dermal (rat) LD50: >2000 mg/kg[1] Inhalation (rat) LC50: 6510.0635325 mg/l/6h[2] Oral (rat) LD50: 5155 mg/kg[1] IRRITATION Eye (rabbit) 230 mg mild Eye (rabbit) 500 mg/24 h. - mild Eye: no adverse effect observed (not irritating)[1] Skin (rabbit) 500 mg open - mild Skin: no adverse effect observed (not irritating)[1] Legend: 1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS. Unless otherwise specified data extracted from RTECS - Register of Toxic Effect of chemical Substances ISOBUTYL ACETATE ACETONE PROPYLENE GLYCOL MONOMETHYL ETHER MIXTURE OF ISOMERS 838 Total Ground Carbon Conductive Coating & PROPYLENE GLYCOL MONOMETHYL ETHER MIXTURE OF ISOMERS The material may produce moderate eye irritation leading to inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis. Inhalation (rat): 8000ppm/4h Skin(rabbit): 500 mg/24hr moderate for acetone: The acute toxicity of acetone is low. Acetone is not a skin irritant or sensitiser but is a defatting agent to the skin. Acetone is an eye irritant. The subchronic toxicity of acetone has been examined in mice and rats that were administered acetone in the drinking water and again in rats treated by oral gavage. Acetone-induced increases in relative kidney weight changes were observed in male and female rats used in the oral 13-week study. Acetone treatment caused increases in the relative liver weight in male and female rats that were not associated with histopathologic effects and the effects may have been associated with microsomal enzyme induction. Haematologic effects consistent with macrocytic anaemia were also noted in male rats along with hyperpigmentation in the spleen. The most notable findings in the mice were increased liver and decreased spleen weights. Overall, the no-observed-effect-levels in the drinking water study were 1% for male rats (900 mg/kg/d) and male mice (2258 mg/kg/d), 2% for female mice (5945 mg/kg/d), and 5% for female rats (3100 mg/kg/d). For developmental effects, a statistically significant reduction in foetal weight, and a slight, but statistically significant increase in the percent incidence of later resorptions were seen in mice at 15,665 mg/m3 and in rats at 26,100 mg/m3. The no-observable-effect level for developmental toxicity was determined to be 5220 mg/m3 for both rats and mice. Teratogenic effects were not observed in rats and mice tested at 26,110 and 15,665 mg/m3, respectively. Lifetime dermal carcinogenicity studies in mice treated with up to 0.2 mL of acetone did not reveal any increase in organ tumor incidence relative to untreated control animals. The scientific literature contains many different studies that have measured either the neurobehavioural performance or neurophysiological response of humans exposed to acetone. Effect levels ranging from about 600 to greater than 2375 mg/m3 have been reported. Neurobehavioral studies with acetone-exposed employees have recently shown that 8-hr exposures in excess of 2375 mg/m3 were not associated with any dose-related changes in response time, vigilance, or digit span scores. Clinical case studies, controlled human volunteer studies, animal research, and occupational field evaluations all indicate that the NOAEL for this effect is 2375 mg/m3 or greater. NOTE: Exposure of pregnant rats and rabbits to the substance did not give rise to teratogenic effects at concentrations up to 3000 ppm. Fetotoxic effects were seen in rats but not in rabbits at this concentration; maternal toxicity was noted in both species. No significant acute toxicological data identified in literature search. The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis. for propylene glycol ethers (PGEs): Typical propylene glycol ethers include propylene glycol n-butyl ether (PnB); dipropylene glycol n-butyl ether (DPnB); dipropylene glycol methyl ether acetate (DPMA); tripropylene glycol methyl ether (TPM). Testing of a wide variety of propylene glycol ethers Testing of a wide variety of propylene glycol ethers has shown that propylene glycol-based ethers are less toxic than some ethers of the ethylene series. The common toxicities associated with the lower molecular weight homologues of the ethylene series, such as adverse effects on reproductive organs, the developing embryo and fetus, blood (haemolytic effects), or thymus, are not seen with the commercial-grade propylene glycol ethers. In the ethylene series, metabolism of the terminal hydroxyl group produces an alkoxyacetic acid. The reproductive and developmental toxicities of the lower molecular weight homologues in the ethylene series are due specifically to the formation of methoxyacetic and ethoxyacetic acids. Longer chain length homologues in the ethylene series are not associated with the reproductive toxicity but can cause haemolysis in sensitive Continued... Page 15 of 24 838 Total Ground Carbon Conductive Coating 838 Total Ground Carbon Conductive Coating & TOLUENE species, also through formation of an alkoxyacetic acid. The predominant alpha isomer of all the PGEs (thermodynamically favored during manufacture of PGEs) is a secondary alcohol incapable of forming an alkoxypropionic acid. In contrast beta-isomers are able to form the alkoxypropionic acids and these are linked to teratogenic effects (and possibly haemolytic effects). This alpha isomer comprises greater than 95% of the isomeric mixture in the commercial product. Because the alpha isomer cannot form an alkoxypropionic acid, this is the most likely reason for the lack of toxicity shown by the PGEs as distinct from the lower molecular weight ethylene glycol ethers. More importantly, however, very extensive empirical test data show that this class of commercial-grade glycol ether presents a low toxicity hazard. PGEs, whether mono, di- or tripropylene glycol-based (and no matter what the alcohol group), show a very similar pattern of low to non-detectable toxicity of any type at doses or exposure levels greatly exceeding those showing pronounced effects from the ethylene series. One of the primary metabolites of the propylene glycol ethers is propylene glycol, which is of low toxicity and completely metabolised in the body. As a class, the propylene glycol ethers are rapidly absorbed and distributed throughout the body when introduced by inhalation or oral exposure. Dermal absorption is somewhat slower but subsequent distribution is rapid. Most excretion for PGEs is via the urine and expired air. A small portion is excreted in the faeces. As a group PGEs exhibits low acute toxicity by the oral, dermal, and inhalation routes. Rat oral LD50s range from >3,000 mg/kg (PnB) to >5,000 mg/kg (DPMA). Dermal LD50s are all > 2,000 mg/kg (PnB, & DPnB; where no deaths occurred), and ranging up to >15,000 mg/kg (TPM). Inhalation LC50 values were higher than 5,000 mg/m3 for DPMA (4-hour exposure), and TPM (1-hour exposure). For DPnB the 4-hour LC50 is >2,040 mg/m3. For PnB, the 4-hour LC50 was >651 ppm (>3,412 mg/m3), representing the highest practically attainable vapor level. No deaths occurred at these concentrations. PnB and TPM are moderately irritating to eyes while the remaining category members are only slightly irritating to nonirritating. PnB is moderately irritating to skin while the remaining category members are slightly to non-irritating None are skin sensitisers. In repeated dose studies ranging in duration from 2 to 13 weeks, few adverse effects were found even at high exposure levels and effects that did occur were mild in nature. By the oral route of administration, NOAELs of 350 mg/kg-d (PnB 13 wk) and 450 mg/kg-d (DPnB 13 wk) were observed for liver and kidney weight increases (without accompanying histopathology). LOAELs for these two chemicals were 1000 mg/kg-d (highest dose tested). Dermal repeated-dose toxicity tests have been performed for many PGEs. For PnB, no effects were seen in a 13-wk study at doses as high as 1,000 mg/kg-d. A dose of 273 mg/kg-d constituted a LOAEL (increased organ weights without histopathology) in a 13-week dermal study for DPnB. For TPM, increased kidney weights (no histopathology) and transiently decreased body weights were found at a dose of 2,895 mg/kg-d in a 90-day study in rabbits. By inhalation, no effects were observed in 2-week studies in rats at the highest tested concentrations of 3244 mg/m3 (600 ppm) for PnB and 2,010 mg/m3 (260 ppm) for DPnB. TPM caused increased liver weights without histopathology by inhalation in a 2-week study at a LOAEL of 360 mg/m3 (43 ppm). In this study, the highest tested TPM concentration, 1010 mg/m3 (120 ppm), also caused increased liver weights without accompanying histopathology. Although no repeated-dose studies are available for the oral route for TPM, or for any route for DPMA, it is anticipated that these chemicals would behave similarly to other category members. One and two-generation reproductive toxicity testing has been conducted in mice, rats, and rabbits via the oral or inhalation routes of exposure on PM and PMA. In an inhalation rat study using PM, the NOAEL for parental toxicity is 300 ppm (1106 mg/m3) with decreases in body and organ weights occurring at the LOAEL of 1000 ppm (3686 mg/m3). For offspring toxicity the NOAEL is 1000 ppm (3686 mg/m3), with decreased body weights occurring at 3000 ppm (11058 mg/m3). For PMA, the NOAEL for parental and offspring toxicity is 1000 mg/kg/d. in a two generation gavage study in rats. No adverse effects were found on reproductive organs, fertility rates, or other indices commonly monitored in such studies. In addition, there is no evidence from histopathological data from repeated-dose studies for the category members that would indicate that these chemicals would pose a reproductive hazard to human health. In developmental toxicity studies many PGEs have been tested by various routes of exposure and in various species at significant exposure levels and show no frank developmental effects. Due to the rapid hydrolysis of DPMA to DPM, DPMA would not be expected to show teratogenic effects. At high doses where maternal toxicity occurs (e.g., significant body weight loss), an increased incidence of some anomalies such as delayed skeletal ossification or increased 13th ribs, have been reported. Commercially available PGEs showed no teratogenicity. The weight of the evidence indicates that propylene glycol ethers are not likely to be genotoxic. In vitro, negative results have been seen in a number of assays for PnB, DPnB, DPMA and TPM. Positive results were only seen in 3 out of 5 chromosome aberration assays in mammalian cells with DPnB. However, negative results were seen in a mouse micronucleus assay with DPnB and PM. Thus, there is no evidence to suggest these PGEs would be genotoxic in vivo. In a 2-year bioassay on PM, there were no statistically significant increases in tumors in rats and mice. For toluene: Acute Toxicity Humans exposed to intermediate to high levels of toluene for short periods of time experience adverse central nervous system effects ranging from headaches to intoxication, convulsions, narcosis, and death. Similar effects are observed in short-term animal studies. Humans - Toluene ingestion or inhalation can result in severe central nervous system depression, and in large doses, can act as a narcotic. The ingestion of about 60 mL resulted in fatal nervous system depression within 30 minutes in one reported case. Constriction and necrosis of myocardial fibers, markedly swollen liver, congestion and haemorrhage of the lungs and acute tubular necrosis were found on autopsy. Central nervous system effects (headaches, dizziness, intoxication) and eye irritation occurred following inhalation exposure to 100 ppm toluene 6 hours/day for 4 days. Exposure to 600 ppm for 8 hours resulted in the same and more serious symptoms including euphoria, dilated pupils, convulsions, and nausea . Exposure to 10,000-30,000 ppm has been reported to cause narcosis and death Toluene can also strip the skin of lipids causing dermatitis Animals - The initial effects are instability and incoordination, lachrymation and sniffles (respiratory exposure), followed by narcosis. Animals die of respiratory failure from severe nervous system depression. Cloudy swelling of the kidneys was reported in rats following inhalation exposure to 1600 ppm, 18-20 hours/day for 3 days Subchronic/Chronic Effects: Repeat doses of toluene cause adverse central nervous system effects and can damage the upper respiratory system, the liver, and the kidney. Adverse effects occur as a result from both oral and the inhalation exposures. A reported lowest-observed-effect level in humans for adverse neurobehavioral effects is 88 ppm. Humans - Chronic occupational exposure and incidences of toluene abuse have resulted in hepatomegaly and liver function changes. It has also resulted in nephrotoxicity and, in one case, was a cardiac sensitiser and fatal cardiotoxin. Neural and cerebellar dystrophy were reported in several cases of habitual 'glue sniffing.' An epidemiological study in France on workers chronically exposed to toluene fumes reported leukopenia and neutropenia. Exposure levels were not given in the secondary reference; however, the average urinary excretion of hippuric acid, a metabolite of toluene, was given as 4 g/L compared to a normal level of 0.6 g/L Animals - The major target organs for the subchronic/chronic toxicity of toluene are the nervous system, liver, and kidney. Depressed immune response has been reported in male mice given doses of 105 mg/kg/day for 28 days. Toluene in corn oil administered to F344 male and female rats by gavage 5 days/week for 13 weeks, induced prostration, hypoactivity, ataxia, piloerection, lachrymation, excess salivation, and body tremors at doses 2500 mg/kg. Liver, kidney, and heart weights were also increased at this dose and histopathologic lesions were seen in the liver, kidneys, brain and urinary bladder. The no-observed-adverse effect level (NOAEL) for the study was 312 mg/kg (223 mg/kg/day) and the lowestobserved-adverse effect level (LOAEL) for the study was 625 mg/kg (446 mg/kg/day) . Developmental/Reproductive Toxicity Exposures to high levels of toluene can result in adverse effects in the developing human foetus. Several studies have indicated that high levels of toluene can also adversely effect the developing offspring in laboratory animals. Humans - Variable growth, microcephaly, CNS dysfunction, attentional deficits, minor craniofacial and limb abnormalities, and developmental delay were seen in three children exposed to toluene in utero as a result of maternal solvent abuse before and during pregnancy Animals - Sternebral alterations, extra ribs, and missing tails were reported following treatment of rats with 1500 mg/m3 toluene 24 hours/day during days 9-14 of gestation. Two of the dams died during the exposure. Another group of rats received 1000 mg/m3 8 hours/day during days 1-21 of gestation. No maternal deaths or toxicity occurred, however, minor skeletal retardation was present in the exposed fetuses. CFLP Mice were exposed to 500 or 1500 mg/m3 toluene continuously during days 6-13 of pregnancy. All dams died at the high dose during the first 24 hours of exposure, however none died at 500 mg/m3. Decreased foetal weight was reported, but there were no differences in the incidences of skeletal Continued... Page 16 of 24 838 Total Ground Carbon Conductive Coating TOLUENE & ISOBUTYL ACETATE & ETHANOL AMYL METHYL KETONE & ACETONE & PROPYLENE GLYCOL MONOMETHYL ETHER - MIXTURE OF ISOMERS malformations or anomalies between the treated and control offspring. Absorption - Studies in humans and animals have demonstrated that toluene is readily absorbed via the lungs and the gastrointestinal tract. Absorption through the skin is estimated at about 1% of that absorbed by the lungs when exposed to toluene vapor. Dermal absorption is expected to be higher upon exposure to the liquid; however, exposure is limited by the rapid evaporation of toluene . Distribution - In studies with mice exposed to radiolabeled toluene by inhalation, high levels of radioactivity were present in body fat, bone marrow, spinal nerves, spinal cord, and brain white matter. Lower levels of radioactivity were present in blood, kidney, and liver. Accumulation of toluene has generally been found in adipose tissue, other tissues with high fat content, and in highly vascularised tissues . Metabolism - The metabolites of inhaled or ingested toluene include benzyl alcohol resulting from the hydroxylation of the methyl group. Further oxidation results in the formation of benzaldehyde and benzoic acid. The latter is conjugated with glycine to yield hippuric acid or reacted with glucuronic acid to form benzoyl glucuronide. o-cresol and p-cresol formed by ring hydroxylation are considered minor metabolites Excretion - Toluene is primarily (60-70%) excreted through the urine as hippuric acid. The excretion of benzoyl glucuronide accounts for 10-20%, and excretion of unchanged toluene through the lungs also accounts for 10-20%. Excretion of hippuric acid is usually complete within 24 hours after exposure. The material may cause skin irritation after prolonged or repeated exposure and may produce a contact dermatitis (nonallergic). This form of dermatitis is often characterised by skin redness (erythema) and swelling the epidermis. Histologically there may be intercellular oedema of the spongy layer (spongiosis) and intracellular oedema of the epidermis. The material may cause skin irritation after prolonged or repeated exposure and may produce a contact dermatitis (nonallergic). This form of dermatitis is often characterised by skin redness (erythema) and swelling epidermis. Histologically there may be intercellular oedema of the spongy layer (spongiosis) and intracellular oedema of the epidermis. ETHYL ACETATE & PROPYLENE GLYCOL MONOMETHYL ETHER MIXTURE OF ISOMERS Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key criteria for the diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms within minutes to hours of a documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without eosinophilia, have also been included in the criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that occurs as result of exposure due to high concentrations of irritating substance (often particulate in nature) and is completely reversible after exposure ceases. The disorder is characterised by dyspnea, cough and mucus production. Acute Toxicity Skin Irritation/Corrosion Serious Eye Damage/Irritation Respiratory or Skin sensitisation Mutagenicity Carcinogenicity Reproductivity STOT - Single Exposure STOT - Repeated Exposure Aspiration Hazard Legend: Data either not available or does not fill the criteria for classification Data available to make classification SECTION 12 ECOLOGICAL INFORMATION 12.1. Toxicity 838 Total Ground Carbon Conductive Coating ENDPOINT Not Available TEST DURATION (HR) Not Available SPECIES Not Available VALUE Not Available SOURCE Not Available toluene ENDPOINT LC50 EC50 EC50 BCF NOEC TEST DURATION (HR) 96 48 72 24 168 SPECIES Fish Crustacea Algae or other aquatic plants Algae or other aquatic plants Crustacea VALUE 0.0073mg/L 3.78mg/L 12.5mg/L 10mg/L 0.74mg/L SOURCE 4 5 4 4 5 isobutyl acetate ENDPOINT LC50 EC50 EC50 NOEC TEST DURATION (HR) 96 48 96 504 SPECIES Fish Crustacea Algae or other aquatic plants Crustacea VALUE 16.6mg/L 24.6mg/L 1.843mg/L 23.2mg/L SOURCE 2 2 3 2 amyl methyl ketone ENDPOINT LC50 EC50 EC50 NOEC TEST DURATION (HR) 96 48 72 72 SPECIES Fish Crustacea Algae or other aquatic plants Algae or other aquatic plants VALUE 30.530mg/L >90.1mg/L 75.5mg/L 42.68mg/L SOURCE 3 2 2 2 Continued... Page 17 of 24 838 Total Ground Carbon Conductive Coating acetone ENDPOINT LC50 EC50 EC50 NOEC TEST DURATION (HR) 96 48 96 240 SPECIES Fish Crustacea Algae or other aquatic plants Crustacea VALUE 5-540mg/L >100mg/L 20.565mg/L 1-866mg/L SOURCE 2 4 4 2 ethanol ENDPOINT LC50 EC50 EC50 NOEC TEST DURATION (HR) 96 48 96 2016 SPECIES Fish Crustacea Algae or other aquatic plants Fish VALUE 11-mg/L 2mg/L 17.921mg/L 0.000375mg/L SOURCE 2 4 4 4 ethyl acetate ENDPOINT LC50 EC50 EC50 BCF NOEC TEST DURATION (HR) 96 48 96 24 48 SPECIES Fish Crustacea Algae or other aquatic plants Algae or other aquatic plants Algae or other aquatic plants VALUE 54.314mg/L 1-350mg/L 4.146mg/L 0.05mg/L >1-mg/L SOURCE 3 2 3 4 2 propylene glycol monomethyl ether - mixture of isomers ENDPOINT LC50 EC50 EC50 NOEC TEST DURATION (HR) 96 48 72 96 SPECIES Fish Crustacea Algae or other aquatic plants Algae or other aquatic plants VALUE 100mg/L 373mg/L >1-mg/L >=1-mg/L SOURCE 1 2 2 2 Legend: Extracted from 1. IUCLID Toxicity Data 2. Europe ECHA Registered Substances - Ecotoxicological Information - Aquatic Toxicity 3. EPIWIN Suite V3.12 (QSAR) - Aquatic Toxicity Data (Estimated) 4. US EPA, Ecotox database - Aquatic Toxicity Data 5. ECETOC Aquatic Hazard Assessment Data 6. NITE (Japan) - Bioconcentration Data 7. METI (Japan) - Bioconcentration Data 8. Vendor Data Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Do NOT allow product to come in contact with surface waters or to intertidal areas below the mean high water mark. Do not contaminate water when cleaning equipment or disposing of equipment wash-waters. Wastes resulting from use of the product must be disposed of on site or at approved waste sites. Within an aromatic series, acute toxicity increases with increasing alkyl substitution on the aromatic nucleus. For example, there is an increase in toxicity as alkylation of the naphthalene structure increases. The order of most toxic to least in a study using grass shrimp (Palaemonetes pugio) and brown shrimp (Penaeus aztecus) was dimethylnaphthalenes > methylnaphthalenes >naphthalenes. Studies conclude that the toxicity of an oil appears to be a function of its di-aromatic and tri-aromatic hydrocarbons, which includes three-ring hydrocarbons such as phenanthrene. The heavier (4-, 5-, and 6-ring) PAHs are more persistent than the lighter (2- and 3-ring) PAHs and tend to have greater carcinogenic and other chronic impact potential. PAHs in general are more frequently associated with chronic risks. These risks include cancer and often are the result of exposures to complex mixtures of chronic-risk aromatics (such as PAHs, alkyl PAHs, benzenes, and alkyl benzenes), rather than exposures to low levels of a single compound. Anthrcene is a phototoxic PAH . UV light greatly increases the toxicity of anthracene to bluegill sunfish. . Benchmarks developed in the absence of UV light may be under-protective, and biological resources in strong sunlight are at more risk than those that are not. When ethanol is released into the soil it readily and quickly biodegrades but may leach into ground water; most is lost by evaporation. When released into water the material readily evaporates and is biodegradable. Ethanol does not bioaccumulate to an appreciable extent. The material is readily degraded by reaction with photochemically produced hydroxy radicals; release into air will result in photodegradation and wet deposition. Environmental Fate: TERRESTRIAL FATE: An estimated Koc value of 1 indicates that ethanol is expected to have very high mobility in soil. Volatilisation of ethanol from moist soil surfaces is expected to be an important fate process given a Henry's Law constant of 5X10-6 atm-m3/mole. The potential for volatilisation of ethanol from dry soil surfaces may exist based upon an extrapolated vapor pressure of 59.3 mmHg. Biodegradation is expected to be an important fate process for ethanol based on half-lives on the order of a few days for ethanol in sandy soil/groundwater microcosms. AQUATIC FATE: An estimated Koc value of 1 indicates that ethanol is not expected to adsorb to suspended solids and sediment. Volatilisation from water surfaces is expected based upon a Henry's Law constant of 5X10-6 atm-m3/mole. Using this Henry's Law constant and an estimation method, volatilisation half-lives for a model river and model lake are 3 and 39 days, respectively.An estimated BCF= 3, from a log Kow of -0.31 suggests bioconcentration in aquatic organisms is low. Hydrolysis and photolysis in sunlit surface waters is not expected to be an important environmental fate process for ethanol since this compound lacks functional groups that hydrolyse or absorb light under environmentally relevant conditions. Ethanol was degraded with half-lives on the order of a few days in aquatic studies conducted using microcosms constructed with a low organic sandy soil and groundwater, indicating it is unlikely to be persistent in aquatic environments(8). ATMOSPHERIC FATE: Ethanol, which has an extrapolated vapor pressure of 59.3 mm Hg at 25 deg C, is expected to exist solely as a vapor in the ambient atmosphere. Vapour-phase ethanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 5 days, calculated from its rate constant of 3.3X10-12 m3/molecule-sec at 25 deg C. Ecotoxicity: log Kow: -0.31- -0.32 Half-life (hr) air: 144 Half-life (hr) H2O surface water: 144 Henry's atm m3 /mol: 6.29E-06 BOD 5 if unstated: 0.93-1.67,63% COD: 1.99-2.11,97% ThOD: 2.1 For ketones: Ketones, unless they are alpha, beta--unsaturated ketones, can be considered as narcosis or baseline toxicity compounds Hydrolysis may also involve the addition of water to ketones to yield ketals under mild acid conditions. However, this addition of water is thermodynamically favorable only for low molecular weight ketones. This addition is an equilibrium reaction that is reversible upon a change of water concentration and the reaction ultimately leads to no permanent change in the structure of the ketone substrateThe higher molecular weight ketones do no form stable ketals. Therefore, the ketones are stable to water under ambient environmental conditions Another possible reaction of ketones in water involves the enolic hydrogen on the carbons bonded to the carbonyl function. Under conditions of high pH (pH greater than 10), the Continued... Page 18 of 24 838 Total Ground Carbon Conductive Coating enolic proton is abstracted by base (OH-) forming a carbanion intermediate that may react with other organic substrates (e.g., ketones, esters, aldehydes) containing a center for nucleophilic attack. The reactions, commonly recognized as condensation reactions, produce higher molecular weight products. Under ambient conditions of temperature, pH, and low concentration, these condensation reactions are unfavorable. Based on its reactions in air, it seems likely that ketones undergo photolysis in water. It is probable that ketones will be biodegraded to an appreciable degree by micro-organisms in soil and water. They are unlikely to bioconcentrate or biomagnify. For toluene: log Kow : 2.1-3 log Koc : 1.12-2.85 Koc : 37-260 log Kom : 1.39-2.89 Half-life (hr) air : 2.4-104 Half-life (hr) H2O surface water : 5.55-528 Half-life (hr) H2O ground : 168-2628 Half-life (hr) soil : <48-240 Henry's Pa m3 /mol: 518-694 Henry's atm m3 /mol: 5.94E-03 BOD 5 0.86-2.12, 5% COD : 0.7-2.52,21-27% ThOD : 3.13 BCF : 1.67-380 log BCF : 0.22-3.28 Environmental fate: Transport: The majority of toluene evaporates to the atmosphere from the water and soil.It is moderately retarded by adsorption to soils rich in organic material (Koc = 259), therefore, transport to ground water is dependent on the soil composition. In unsaturated topsoil containing organic material, it has been estimated that 97% of the toluene is adsorbed to the soil and only about 2% is in the soil-water phase and transported with flowing groundwater. There is little retardation in sandy soils and 2-13% of the toluene was estimated to migrate with flowing water; the remainder was volatilised, biodegraded, or unaccounted for. In saturated deep soils with no soil-air phase, about 48% may be transported with flowing groundwater. Transformation/Persistence: Air - The main degradation pathway for toluene in the atmosphere is reaction with photochemically produced hydroxyl radicals. The estimated atmospheric half life for toluene is about 13 hours. Toluene is also oxidised by reactions with atmospheric nitrogen dioxide, oxygen, and ozone, but these are minor degradation pathways. Photolysis is not considered a significant degradative pathway for toluene Soil - In surface soil, volatilisation to air is an important fate process for toluene. Biodegradation of toluene has been demonstrated in the laboratory to occur with a half life of about 1 hour. In the environment, biodegradation of toluene to carbon dioxide occurs with a typical half life of 1-7 days. Water - An important fate process for toluene is volatilization, the rate of which depends on the amount of turbulence in the surface water .The volatilisation of toluene from static water has a half life of 1-16 days, whereas from turbulent water the half life is 5-6 hours. Degradation of toluene in surface water occurs primarily by biodegradation with a half life of less than one day under favorable conditions (presence of microorganisms, microbial adaptation, and optimum temperature). Biodegradation also occurs in shallow groundwater and in salt water at a reduced rate). No data are available on anaerobic degradation of toluene in deep ground water conditions where aerobic degradation would be minimal . Biota - Bioaccumulation in most organisms is limited by the metabolism of toluene into more polar compounds that have greater water solubility and a lower affinity for lipids. Bioaccumulation in the food chain is predicted to be low. Ecotoxicity: Toluene has moderate acute toxicity to aquatic organisms; several toxicity values are in the range of greater than 1 mg/L and 100 mg/L. Fish LC50 (96 h): fathead minnow (Pimephales promelas) 12.6-72 mg/l; Lepomis macrochirus 13-24 mg/l; guppy (Poecilia reticulata) 28.2-59.3 mg/l; channel catfish (Ictalurus punctatus) 240 mg/l; goldfish (Carassius auratus): 22.8-57.68 mg/l Crustaceans LC50 (96 h): grass shrimp (Palaemonetes pugio) 9.5 ppm, crab larvae stage (Cancer magister) 28 ppm; shrimp (Crangon franciscorum) 4.3 ppm; daggerblade grass shrimp (Palaemonetes pugio) 9.5 mg/l Algae EC50 (24 h): green algae (Chlorella vulgaris) 245 mg/l (growth); (72 h) green algae (Selenastrum capricornutum) 12.5 mg/l (growth) for acetone: log Kow: -0.24 Half-life (hr) air: 312-1896 Half-life (hr) H2O surface water: 20 Henry's atm m3 /mol: 3.67E-05 BOD 5: 0.31-1.76,46-55% COD: 1.12-2.07 ThOD: 2.2 BCF: 0.69 Environmental fate: Acetone preferentially locates in the air compartment when released to the environment. A substantial amount of acetone can also be found in water, which is consistent with the high water to air partition coefficient and its small, but detectable, presence in rain water, sea water, and lake water samples. Very little acetone is expected to reside in soil, biota, or suspended solids. This is entirely consistent with the physical and chemical properties of acetone and with measurements showing a low propensity for soil absorption and a high preference for moving through the soil and into the ground water In air, acetone is lost by photolysis and reaction with photochemically produced hydroxyl radicals; the estimated half-life of these combined processes is about 22 days. The relatively long half-life allows acetone to be transported long distances from its emission source. Acetone is highly soluble and slightly persistent in water, with a half-life of about 20 hours; it is minimally toxic to aquatic life. Acetone released to soil volatilises although some may leach into the ground where it rapidly biodegrades. Acetone does not concentrate in the food chain. Acetone meets the OECD definition of readily biodegradable which requires that the biological oxygen demand (BOD) is at least 70% of the theoretical oxygen demand (THOD) within the 28-day test period Drinking Water Standard: none available. Soil Guidelines: none available. Air Quality Standards: none available. Ecotoxicity: Testing shows that acetone exhibits a low order of toxicity Fish LC50: brook trout 6070 mg/l; fathead minnow 15000 mg/l Bird LC0 (5 day): Japanese quail, ring-neck pheasant 40,000 mg/l Daphnia magna LC50 (48 h): 15800 mg/l; NOEC 8500 mg/l Aquatic invertebrate 2100 - 16700 mg/l Aquatic plant NOEC: 5400-7500 mg/l Daphnia magna chronic NOEC 1660 mg/l Acetone vapors were shown to be relatively toxic to two types insects and their eggs. The time to 50% lethality (LT50) was found to be 51.2 hr and 67.9 hr when the flour beetle (Tribolium confusum) and the flour moth (Ephestia kuehniella) were exposed to an airborne acetone concentration of 61.5 mg/m3. The LT50 values for the eggs were 30-50% lower than for the adult. The direct application of acetone liquid to the body of the insects or surface of the eggs did not, however, cause any mortality. The ability of acetone to inhibit cell multiplication has been examined in a wide variety of microorganisms. The results have generally indicated mild to minimal toxicity with NOECs greater than 1700 mg/L for exposures lasting from 6 hr to 4 days. Longer exposure periods of 7 to 8 days with bacteria produced mixed results; but overall the data indicate a low degree of toxicity for acetone. The only exception to these findings were the results obtained with the flagellated protozoa (Entosiphon sulcatum) which yielded a 3-day NOEC of 28 mg/L. DO NOT discharge into sewer or waterways. 12.2. Persistence and degradability Continued... Page 19 of 24 838 Total Ground Carbon Conductive Coating Ingredient toluene isobutyl acetate amyl methyl ketone acetone ethanol ethyl acetate propylene glycol monomethyl ether - mixture of isomers Persistence: Water/Soil LOW (Half-life = 28 days) LOW LOW LOW (Half-life = 14 days) LOW (Half-life = 2.17 days) LOW (Half-life = 14 days) LOW (Half-life = 56 days) 12.3. Bioaccumulative potential Ingredient Bioaccumulation toluene LOW (BCF = 90) isobutyl acetate LOW (LogKOW = 1.78) amyl methyl ketone LOW (LogKOW = 1.98) acetone LOW (BCF = 0.69) ethanol LOW (LogKOW = -0.31) ethyl acetate HIGH (BCF = 3300) propylene glycol monomethyl ether - mixture of isomers LOW (BCF = 2) 12.4. Mobility in soil Ingredient toluene isobutyl acetate amyl methyl ketone acetone ethanol ethyl acetate propylene glycol monomethyl ether - mixture of isomers Mobility LOW (KOC = 268) LOW (KOC = 17.48) LOW (KOC = 24.01) HIGH (KOC = 1.981) HIGH (KOC = 1) LOW (KOC = 6.131) HIGH (KOC = 1) 12.5.Results of PBT and vPvB assessment Relevant available data P Not Applicable PBT Criteria fulfilled? Not Applicable Persistence: Air LOW (Half-life = 4.33 days) LOW LOW MEDIUM (Half-life = 116.25 days) LOW (Half-life = 5.08 days) LOW (Half-life = 14.71 days) LOW (Half-life = 1.7 days) B Not Applicable Not Applicable T Not Applicable Not Applicable 12.6. Other adverse effects No data available SECTION 13 DISPOSAL CONSIDERATIONS 13.1. Waste treatment methods Product / Packaging disposal Containers may still present a chemical hazard/ danger when empty. Return to supplier for reuse/ recycling if possible. Otherwise: If container can not be cleaned sufficiently well to ensure that residuals do not remain or if the container cannot be used to store the same product, then puncture containers, to prevent re-use, and bury at an authorised landfill. Where possible retain label warnings and SDS and observe all notices pertaining to the product. Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. In some areas, certain wastes must be tracked. A Hierarchy of Controls seems to be common - the user should investigate: Reduction Reuse Recycling Disposal (if all else fails) This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use. If it has been contaminated, it may be possible to reclaim the product by filtration, distillation or some other means. Shelf life considerations should also be applied in making decisions of this type. Note that properties of a material may change in use, and recycling or reuse may not always be appropriate. DO NOT allow wash water from cleaning or process equipment to enter drains. It may be necessary to collect all wash water for treatment before disposal. In all cases disposal to sewer may be subject to local laws and regulations and these should be considered first. Where in doubt contact the responsible authority. Recycle wherever possible. Consult manufacturer for recycling options or consult local or regional waste management authority for disposal if no suitable treatment or disposal facility can be identified. Dispose of by: burial in a land-fill specifically licensed to accept chemical and / or pharmaceutical wastes or Incineration in a licensed Continued... Page 20 of 24 838 Total Ground Carbon Conductive Coating Waste treatment options Sewage disposal options apparatus (after admixture with suitable combustible material). Decontaminate empty containers. Observe all label safeguards until containers are cleaned and destroyed. Not Available Not Available SECTION 14 TRANSPORT INFORMATION Labels Required Limited Quantity: 838-900ML, 838-1G Land transport (ADR) 14.1. UN number 14.2. UN proper shipping name 14.3. Transport hazard class(es) 14.4. Packing group 14.5. Environmental hazard 14.6. Special precautions for user 1263 PAINT or PAINT RELATED MATERIAL Class Subrisk 3 Not Applicable II Not Applicable Hazard identification (Kemler) Classification code Hazard Label Special provisions Limited quantity Tunnel Restriction Code 33 F1 3 163 367 640C 640D 650 5 L 2 (D/E) Air transport (ICAO-IATA / DGR) 14.1. UN number 14.2. UN proper shipping name 1263 PAINT or PAINT RELATED MATERIAL 14.3. Transport hazard class(es) ICAO/IATA Class ICAO / IATA Subrisk ERG Code 3 Not Applicable 3L 14.4. Packing group 14.5. Environmental hazard II Not Applicable 14.6. Special precautions for user Special provisions Cargo Only Packing Instructions Cargo Only Maximum Qty / Pack Passenger and Cargo Packing Instructions Passenger and Cargo Maximum Qty / Pack Passenger and Cargo Limited Quantity Packing Instructions Passenger and Cargo Limited Maximum Qty / Pack A3 A72 A192 364 60 L 353 5 L Y341 1 L Sea transport (IMDG-Code / GGVSee) 14.1. UN number 14.2. UN proper shipping name 1263 PAINT or PAINT RELATED MATERIAL 14.3. Transport hazard class(es) IMDG Class IMDG Subrisk 3 Not Applicable 14.4. Packing group 14.5. Environmental hazard II Not Applicable 14.6. Special precautions for user EMS Number Special provisions Limited Quantities F-E , S-E 163 367 5 L Continued... Page 21 of 24 838 Total Ground Carbon Conductive Coating Inland waterways transport (ADN) 14.1. UN number 14.2. UN proper shipping name 1263 PAINT or PAINT RELATED MATERIAL 14.3. Transport hazard class(es) 3 Not Applicable 14.4. Packing group 14.5. Environmental hazard II Not Applicable 14.6. Special precautions for user Classification code Special provisions Limited quantity Equipment required Fire cones number F1 163; 367; 640C; 650; 640D 5 L PP, EX, A 1 14.7. Transport in bulk according to Annex II of MARPOL and the IBC code Not Applicable SECTION 15 REGULATORY INFORMATION 15.1. Safety, health and environmental regulations / legislation specific for the substance or mixture TOLUENE IS FOUND ON THE FOLLOWING REGULATORY LISTS EU Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products - Annex III - List of Substances which cosmetic products must not contain except subject to the restrictions laid down EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) EU European Chemicals Agency (ECHA) Community Rolling Action Plan (CoRAP) List of Substances EU REACH Regulation (EC) No 1907/2006 - Annex XVII - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, mixtures and articles Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Trade Union Confederation (ETUC) Priority List for REACH Authorisation European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO MARPOL (Annex II) - List of Noxious Liquid Substances Carried in Bulk IMO Provisional Categorization of Liquid Substances - List 3: (Trade-named) mixtures containing at least 99% by weight of components already assessed by IMO, presenting safety hazards International Agency for Research on Cancer (IARC) - Agents Classified by the IARC Monographs International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations ISOBUTYL ACETATE IS FOUND ON THE FOLLOWING REGULATORY LISTS Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO MARPOL (Annex II) - List of Noxious Liquid Substances Carried in Bulk International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations AMYL METHYL KETONE IS FOUND ON THE FOLLOWING REGULATORY LISTS Continued... Page 22 of 24 838 Total Ground Carbon Conductive Coating EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO MARPOL (Annex II) - List of Noxious Liquid Substances Carried in Bulk International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations ACETONE IS FOUND ON THE FOLLOWING REGULATORY LISTS EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Trade Union Confederation (ETUC) Priority List for REACH Authorisation European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO IBC Code Chapter 18: List of products to which the Code does not apply IMO MARPOL 73/78 (Annex II) - List of Other Liquid Substances International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations ETHANOL IS FOUND ON THE FOLLOWING REGULATORY LISTS Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO IBC Code Chapter 18: List of products to which the Code does not apply IMO MARPOL 73/78 (Annex II) - List of Other Liquid Substances IMO Provisional Categorization of Liquid Substances - List 2: Pollutant only mixtures containing at least 99% by weight of components already assessed by IMO IMO Provisional Categorization of Liquid Substances - List 3: (Trade-named) mixtures containing at least 99% by weight of components already assessed by IMO, presenting safety hazards International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations ETHYL ACETATE IS FOUND ON THE FOLLOWING REGULATORY LISTS EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO MARPOL (Annex II) - List of Noxious Liquid Substances Carried in Bulk International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations PROPYLENE GLYCOL MONOMETHYL ETHER - MIXTURE OF ISOMERS IS FOUND ON THE FOLLOWING REGULATORY LISTS Continued... Page 23 of 24 838 Total Ground Carbon Conductive Coating EU Consolidated List of Indicative Occupational Exposure Limit Values (IOELVs) EU REACH Regulation (EC) No 1907/2006 - Annex XVII (Appendix 6) Toxic to reproduction: category 1B (Table 3.1)/category 2 (Table 3.2) Europe ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways Europe AeroSpace and Defence Industries Association of Europe (ASD) REACH Implementation Working Group Priority Declarable Substances List (PDSL) Europe EC Inventory Europe ECHA Registered Substances - Classification and Labelling - DSD-DPD Europe European Agreement concerning the International Carriage of Dangerous Goods by Road Europe European Customs Inventory of Chemical Substances European Chemical Agency (ECHA) Classification & Labelling Inventory - Chemwatch Harmonised classification European Trade Union Confederation (ETUC) Priority List for REACH Authorisation European Union - European Inventory of Existing Commercial Chemical Substances (EINECS) European Union (EU) Annex I to Directive 67/548/EEC on Classification and Labelling of Dangerous Substances - updated by ATP: 31 European Union (EU) Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures - Annex VI European Union (EU) Transport of Dangerous Goods by Road - Dangerous Goods List GESAMP/EHS Composite List - GESAMP Hazard Profiles IMO IBC Code Chapter 17: Summary of minimum requirements IMO MARPOL (Annex II) - List of Noxious Liquid Substances Carried in Bulk International Air Transport Association (IATA) Dangerous Goods Regulations International Maritime Dangerous Goods Requirements (IMDG Code) Regulations concerning the International Carriage of Dangerous Goods by Rail - Table A: Dangerous Goods List - RID 2019 (English) UK Workplace Exposure Limits (WELs) United Nations Recommendations on the Transport of Dangerous Goods Model Regulations This safety data sheet is in compliance with the following EU legislation and its adaptations - as far as applicable - : Directives 98/24/EC, - 92/85/EEC, - 94/33/EC, - 2008/98/EC, 2010/75/EU; Commission Regulation (EU) 2015/830; Regulation (EC) No 1272/2008 as updated through ATPs. 15.2. Chemical safety assessment No Chemical Safety Assessment has been carried out for this substance/mixture by the supplier. National Inventory Status National Inventory Australia - AICS Canada - DSL Canada - NDSL China - IECSC Europe - EINEC / ELINCS / NLP Japan - ENCS Korea - KECI New Zealand - NZIoC Philippines - PICCS USA - TSCA Taiwan - TCSI Mexico - INSQ Vietnam - NCI Russia - ARIPS Legend: Status Yes Yes No (toluene; acetone; ethyl acetate; ethanol; isobutyl acetate; amyl methyl ketone) Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes = All CAS declared ingredients are on the inventory No = One or more of the CAS listed ingredients are not on the inventory and are not exempt from listing(see specific ingredients in brackets) SECTION 16 OTHER INFORMATION Revision Date Initial Date 17/03/2020 12/03/2014 Full text Risk and Hazard codes H226 H302 H332 H361d H373 Flammable liquid and vapour. Harmful if swallowed. Harmful if inhaled. Suspected of damaging the unborn child. May cause damage to organs through prolonged or repeated exposure. SDS Version Summary Version 2.7.1.1.1 Issue Date 28/10/2019 Sections Updated Acute Health (eye), Acute Health (inhaled), Acute Health (skin), Acute Health (swallowed), Advice to Doctor, Chronic Health, Classification, Environmental, Exposure Standard, First Aid (eye), First Aid (inhaled), First Aid (skin), Handling Procedure, Ingredients, Physical Properties, Spills (major), Storage (storage incompatibility), Synonyms, Use Other information Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. The SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered. For detailed advice on Personal Protective Equipment, refer to the following EU CEN Standards: EN 166 Personal eye-protection EN 340 Protective clothing EN 374 Protective gloves against chemicals and micro-organisms Continued... Page 24 of 24 838 Total Ground Carbon Conductive Coating EN 13832 Footwear protecting against chemicals EN 133 Respiratory protective devices Definitions and abbreviations PCTWA: Permissible Concentration-Time Weighted Average PCSTEL: Permissible Concentration-Short Term Exposure Limit IARC: International Agency for Research on Cancer ACGIH: American Conference of Governmental Industrial Hygienists STEL: Short Term Exposure Limit TEEL: Temporary Emergency Exposure Limit IDLH: Immediately Dangerous to Life or Health Concentrations OSF: Odour Safety Factor NOAEL :No Observed Adverse Effect Level LOAEL: Lowest Observed Adverse Effect Level TLV: Threshold Limit Value LOD: Limit Of Detection OTV: Odour Threshold Value BCF: BioConcentration Factors BEI: Biological Exposure Index Reason for Change A-1.01 - Update to the emergency phone number information. end of SDSUcorp Pty Ltd t/as Chemwatch using ABCpdf