DHM Allergy(2010)
User Manual: DHM
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TESTS FOR ALLERGY
In August 2009 we commissioned new allergy test systems that further extend our testing menu. Our new technology
detects Specic IgE to clinically important individual allergen molecules. We continue to offer testing for allergens to
whole food and inhalant allergens. The main analyser platforms and reagent systems are the Phadia ImmunoCAP 250,
ImmunoCAP 1000 and ISAC ImmunoCAP. Our comprehensive menu is included in this brochure. You may request the
allergens using their alphanumeric codes. Please precede these codes with “Specic IgE for”, or “Allergy serology for”,
or “RAST for”.
NEW TECHNOLOGY
Dear Colleague,
Welcome to our new Allergy Test Menu, one
of the largest internationally available allergy
testing menus. All our specic IgE testing is
now performed on the Phadia ImmunoCAP
250 and Phadia ImmunoCAP 1000 system
(pages 3-10). An advantage of the Phadia
ImmunoCAP system is that, for certain key
foods, the 95% probability of a positive
food challenge has been determined for
certain levels of allergen-specic IgE (see
Table below). We will continue to report
allergen specic IgE values in kU/L and a
semiquantitative class value. Please note
that some patients with a “negative” or “0”
class may have detectable traces of specic
IgE that can have clinical signicance as
a marker of early sensitisation or previous
signicant sensitisation to insect venoms
and drugs. In the most important practical
advance in laboratory allergy diagnostics,
the Phadia ImmunoCAP ISAC system now
allows us to determine a patient’s specic IgE
to 103 clinically important allergen molecules
from 47 different allergens. Tests that dene
the molecule in a food to which a patient
has signicant specic IgE, can provide
diagnostic and prognostic information
for patients with serious food allergy. Our
new technology allows us to do this with
recombinant ImmunoCAP allergens (page
10) or as a prole with the ISAC system
(page 11). We continue to offer other tests
important for assessing allergy problems:
Total IgE, Tryptase, Eosinophilic Cationic
Protein (ECP), C1 esterase and genetic
testing for Hereditary Angioedema Types I, II
and III (see next page).
We have always taken the view that we
should offer the best available allergy testing
systems and give patients the opportunity
to cover the cost of more denitive higher
quality testing that the government will not
meet. In May 2009, the Medicare Benets
Schedule reduced rebates for Allergy
testing by 1%: a reimbursement that is now
less than 20% of rebates in comparable
countries for laboratory allergy testing. It
is almost impossible to answer a simple,
sensible laboratory allergy testing request
within the constraints of the level of Medicare
reimbursement. Consequently, the laboratory
is unable to accept Medicare reimbursement
for more than very basic allergy testing
requests. In this menu, we seek to give
your patients clear options and choices
when it comes to allergy testing. You and
your patients will be pleased to know that
although some new allergens and mixes are
more expensive, core individual allergens and
extended panels are cheaper than previously.
Please send email enquiries to
kbaumgart@dhm.com.au or
Phone: 02 98 555 286
Karl W Baumgart
Director, Immunology
ALLERGEN SPECIFIC IgE
Specic IgE Levels Conferring Very High Risk
ALLERGEN kU/L PPV
Egg (<= 2yo) 2 95%
Egg (> 2yo) 7 98%
Milk (<=2 yo) 5 95%
Milk (>2 yo) 15 95%
Peanut 14 100%
Fish 20 100%
Tree nuts ~15 ~95%
Wheat 26 74%
This table was derived from several large studies in which
patients were challenged with the food. The positive predictive
value (PPV) of a specic IgE level for a positive challenge
was determined. It illustrates that specic IgE levels for
individual allergens are like “international currencies” and are
not necessarily comparable for a particular level for all the
allergens. It denes levels at which a challenge, or exposure,
would be highly hazardous for a patient. Importantly, many
patients could have serious reactions at much lower levels.
ORDERING ALLERGY TESTS
We ask that you specically nominate which allergens you
would like tested. Please do not write the allergens to be
tested in the clinical notes section of the request form. A
comprehensive menu of allergens that we stock and test for
is available in the following pages. If allergens are not available
we may use cross-reactive ones or advise you on the report.
Some “allergy symptoms” may result from intolerance
mechanisms (salicylates, amines, MSG, metabisulphite)
and detection of IgE to them is not useful or possible. You
can request the allergens using their alphanumeric codes.
To assist staff performing data entry, we appreciate it if you
precede these codes by “Specic IgE for” or “Allergy serology
for” or “RAST for”.
If you simply write “RAST” we will now test as follows:
Child 6 years or less: dust mite, egg white, cow’s milk,
peanut and soy (Panel A1)
Adult or child over 6 years: dust mite, cat, dog, grass pollen
and alternaria (Panel A2)
If you write “food and inhalant allergens”, we will test a staple
food mix (Fx5, that includes egg white, cow’s milk, peanut,
soy, wheat and codsh), dust mite, fescue grass pollen-which
cross-reacts with almost all other grasses and, alternaria-an
outdoor mould with small spores that can easily be inhaled
into the small airways (Panel A16). We do recommend some
extended panels of individual allergens and can specically
design panels for you and your patients.
INITIAL INVESTIGATION PANELS
If you write “RAST” or “Allergy serology”, but do not specify the allergens,
we will perform the tests listed under A1 (for a child 6 years or less) or
A2 (Adult, or child over 6 years). Any subsequently requested additional
allergens are charged according to the billing policy listed below.
A20 INHALANTS
D1 Dustmite
E1 Cat Epithelium
E5 Dog
E3 Horse Dander
D201 Blomia tropicalis
G2 Bermuda Grass
G4 Grass pollen (fescue)
G5 Perennial Rye Grass
E82 Rabbit Epithelium
W1 Common Ragweed
W9 English Plantain
W10 Lamb’s Quarters
W21 Parietaria judaica
T18 Eucalyptus
T19 Acacia
T21 Melaleuca
T73 Australian Pine
M2 Cladosporium herbarum
M3 Aspergillus fumigatus
M6 Alternaria alternata
A21 MOULD & STORAGE MITES
M1 Penicillium notatum
M2 Cladosporium herbarum
M3 Aspergillus fumigatus
M4 Mucor racemosus
M5 Candida albicans
M6 Alternaria alternata
M8 Helminthosporium
M9 Fusarium moniliforme
M10 Stemphylium botryosum
M13 Phoma betae
M14 Epicoccum purpurascens
M15 Trichoderma viride
M70 Pityrosporum orbiculare
D1 D. pteronyssinus
D70 Acarus siro
D71 Lepidoglyphus destructor
D72 Tyrophagus putrescentiae
D73 Glycyphagus domesticus
D74 Euroglyphus maynei
D201 Blomia tropicalis
A22 FOODS
F1 Egg White
F2 Milk
F3 Codfish
F4 Wheat
F5 Rye
F6 Barley
F9 Rice
F10 Sesame Seed
F13 Peanut
F14 Soybean
F17 Hazelnut
F20 Almond
F27 Beef
F33 Orange
F35 Potato
F44 Strawberry
F45 Yeast
F84 Kiwi Fruit
F91 Mango
F92 Banana
A23 ANAPHYLACTIC FOODS
F3 Codfish
F10 Sesame Seed
F13 Peanut
F17 Hazelnut
F18 Brazil Nut
F20 Almond
F23 Crab
F24 Prawn
F27 Beef
F36 Coconut
F40 Tuna
F41 Salmon
F80 Lobster
F84 Kiwi Fruit
F91 Mango
F92 Banana
F201 Pecan Nut
F256 Walnut
F290 Oyster
K82 Latex
D1 Dustmite
E1 Cat Epithelium
E82 Rabbit Epithelium
E5 Dog
E3 Horse Dander
G2 Bermuda Grass
G4 Grass Pollen (fescue)
G5 Perennial Rye Grass
W21 Parietaria judaica
M6 Alternaria alternata
F1 Egg White
F75 Egg Yolk
F2 Milk
F3 Codsh
F14 Soybean
F4 Wheat
F10 Sesame Seed
F13 Peanut
F202 Cashew
F17 Hazelnut
F35 Potato
F84 Kiwi Fruit
F91 Mango
F92 Banana
K82 Latex
M80 Staph. Enterotoxin A
M70 Pityrosporum orbiculare
A8 NATIVE TREES
T18 Eucalyptus
T19 Acacia
T21 Melaleuca
T73 Australian Pine
A9 FOOD SCREEN
FX1 Nut Mix
F23 Crab
F4 Wheat
F1 Egg
A10 NUTS
F13 Peanut
F17 Hazelnut
F20 Almond
F201 Pecan nut
A11 SEAFOOD
F3 Codfish
F23 Crab
F24 Prawn
F80 Lobster
OTHER COMMON INITIAL INVESTIGATION PANELS
* Please write the name and code of the panel on the request form. One (1) of our panels is within our allowance under Medicare
A3 CHILD ALLERGY ASSESSMENT PANEL (REQUEST “IgE AND RAST A3”)
This new panel is designed for the assessment of children at high risk of allergic disease, especially those with eczema, possible food and inhalant allergies.
The cost of this panel is $108, for which a Medicare rebate of $22.95 may be available.
EXTENDED ALLERGEN PANEL EXAMPLES
* Our charge for each of these panels is $80, for which a rebate of $22.95 may be available per episode. Each allergen may also be ordered separately by its
code or name. Other personalised extended panels are available on request. Please call Dr Karl Baumgart to discuss your requirements.
A1: CHILD 6 years or less
Total IgE
D1 Dustmite
F1 Egg white
F2 Cow’s milk
F13 Peanut
F14 Soy
A2: ADULT, or CHILD over 6 years
Total IgE
D1 Dustmite
G4 Grass pollen (Fescue)
E1 Cat
E5 Dog
M6 Alternaria
TOTAL IgE
Normal total IgE levels (< 100 kU/L) do not exclude significant allergies. Patients with normal total IgE levels can still be allergic to bee venom,
dustmite, and many other allergens.
Significant specific IgE levels are extraordinarily rare in individuals with total IgE values of less than 7 kU/L.
Persons with very elevated total IgE levels are more likely to have significant elevations in specific IgE. Very elevated levels of total IgE also occur in
persons with severe eczema, helminthic and parasitic infestations as well as allergobronchopulmonary aspergillosis (ABPA). Monitoring total IgE levels
is useful in patients on immunosuppression for their severe eczema as well as in ABPA.
TRYPTASE
Elevated levels of mast cell tryptase in peripheral blood indicate systemic mast cell degranulation or an increased number of mast cells which can
occur in patients with mastocytosis.
Tryptase is NOT ELEVATED in persons with anaphylaxis from foods or non-parenteral agents.
Elevated levels indicate an adverse reaction to a stinging insect or a reaction to an intravenous, intramuscular or subcutaneous diagnostic or
therapeutic agent. Any elevated tryptase levels should be repeated after a period of time (3-10 days) to document a return to normal levels.
Persistently elevated levels of tryptase are strongly suggestive of systemic mastocytosis which may not always manifest with urticaria pigmentosa.
Since mastocytosis is more common in persons with stinging insect reactions, persons who have had systemic reactions to stinging insects should
always have their tryptase level checked together with relevant venom specific IgE. The test is performed on serum. Normal values are < 13.5 ug/L.
For these indications, the test is Medicare rebatable.
EOSINOPHILIC CATIONIC PROTEIN (ECP)
ECP is elevated in persons with active eosinophilic inflammation. It is a useful marker in the diagnosis and management of hypereosinophilic
disorders. ECP is also a useful marker of allergic airways inflammation in young children.
The test is performed on serum. Normal values for children are < 20 ug/L and adults < 15 ug/L.
At present the test is only reimbursed by Medicare when requested in children under 12 years of age for assessment of airways inflammation (Please
write “asthma” on clinical notes). For all other requests, the fee is $50, non-rebatable.
Type I & II (C1 ESTERASE INHIBITOR) HEREDITARY ANGIOEDEMA
This should be considered in anyone with a family history of angioedema without urticaria. C1 esterase level and function, C3 and C4 should be
measured at the same time to facilitate interpretation of the results. Abnormal levels occur in persons with deficiency which has autosomal dominant
inheritance. Persons with this disorder usually experience symptoms from puberty onwards and may have life-threatening episodes which are not
responsive to adrenaline. Many patients also experience recurrent abdominal pain due to visceral angioedema. Functional deficiency may occur on a
genetic basis or in older persons it can result from an interfering autoantibody associated with lymphoma. Abnormal functional assay results should
always be repeated.
The C3, C4, quantitative and functional C1-esterase (C1-inhibitor) assays are performed on serum and reimbursed by Medicare. Sequencing for the
detection of mutations causing Type I and II HAE is performed by the laboratory and the fee is $395 (non-rebatable).
TYPE III (FACTOR XII) HEREDITARY ANGIOEDEMA
This should also be considered, mainly in women, who have angioedema without urticaria. Type III (Factor XII) Hereditary Angioedema is detected by
a real-time PCR assay which detects the most common mutation in Factor XII. This is a cause of angioedema without urticaria in women. This is the
only assay for this disorder which is thought to be at least as common as Type I and Type II HAE. At present there is a non-rebatable fee of $120.
The laboratory can also perform sequencing of Factor XII if required. The fee is $395 (non-rebatable).
A4 ANIMAL INHALANTS
E1 Cat
E5 Dog
D1 Dustmite
G4 Grass pollen
A5 RURAL INHALANTS
G17 Paspalum
WX1 Weed mix
MX1 Mould mix
A6 PETS
E1 Cat
E5 Dog
E6 Guinea pig
E82 Rabbit
A7 MOULDS
M2 Cladosporium
M3 Aspergillus
M5 Candida albicans
M6 Alternaria
OTHER COMMON INITIAL INVESTIGATION PANELS
* Please write the name and code of the panel on the request form. One (1) of our panels is within our allowance under Medicare
A12 CEREALS
F4 Wheat
F6 Barley
F9 Rice
F14 Soy
A13 STAPLE FOODS
F1 Egg white
F2 Milk
F13 Peanut
F14 Soybean
A14 INSECTS
I1 Honey bee venom
I4 Paper wasp venom
I3 Yellow Jacket
I70 Fire ant venom
I71 Mosquito
A15 LATEX & FOODS
K82 Latex
F84 Kiwi fruit
F87 Melon
F92 Banana
A16 FOOD & INHALANTS
FX5 Staple Foods G4 Grass Pollen (fescue) D1 Dust Mite M6 Alternaria
2 3
CORE INDIVIDUAL ALLERGENS
cCore individual allergens, $4 each
Note: Requests for more than ve of these will exceed our allowance under Medicare
FOOD
cF1 Egg white
cF2 Milk
cF3 Fish (cod)
cF4 Wheat
cF5 Rye
cF6 Barley
cF7 Oat
cF8 Maize (Corn)
cF9 Rice
cF10 Sesame seed
cF11 Buckwheat
cF12 Pea
cF13 Peanut
cF14 Soya bean
cF15 White bean
cF17 Hazel nut
cF18 Brazil nut
cF20 Almond
cF23 Crab
cF24 Shrimp
cF25 Tomato
cF26 Pork
cF27 Beef
cF31 Carrot
cF33 Orange
cF35 Potato
cF36 Coconut
cF37 Blue mussel
cF40 Tuna
cF41 Salmon
cF44 Strawberry
cF45 Yeast (S. cerevisiae)
cF47 Garlic
cF48 Onion
cF49 Apple
cF59 Octopus
cF75 Egg yolk
cF79 Gluten
cF80 Lobster
cF81 Cheese Cheddar-type
cF82 Cheese Mould-type
cF83 Chicken meat
cF84 Kiwi fruit
cF85 Celery
cF86 Parsley
cF87 Melons
cF88 Mutton
cF89 Mustard
cF90 Malt
cF91 Mango fruit
cF92 Banana
cF93 Cacao
cF94 Pear
cF95 Peach
cF96 Avocado
cF201 Pecan nut
cF202 Cashew nut
cF203 Pistachio
cF204 Trout
cF207 Clam
cF208 Lemon
cF209 Grapefruit
cF210 Pineapple
eF211 Blackberry
cF212 Mushroom (champignon)
cF214 Spinach
cF215 Lettuce
cF216 Cabbage
cF218 Paprika (sweet pepper)
cF220 Cinnamon
cF221 Coffee
cF222 Tea
cF224 Poppy seed
cF225 Pumpkin
cF226 Pumpkin seed
cF235 Lentil
cF237 Apricot
cF242 Cherry
cF244 Cucumber
cF247 Honey
cF253 Pine nut (pignoles)
cF255 Plum
cF256 Walnut
cF258 Squid
cF259 Grape
cF260 Broccoli
cF261 Asparagus
cF262 Aubergine (eggplant)
cF263 Green pepper (unripe seed)
cF267 Cardamon
cF270 Ginger
cF279 Chili pepper
cF280 Black pepper
cF281 Curry
cF284 Turkey meat
cF287 Red Kidney Bean
cF290 Oyster
cF291 Cauliower
cF293 Papaya
cF294 Passionfruit
cF299 Sweet Chestnut
cF300 Goat milk
cF302 Mandarin
cF309 Chickpea
cF315 Green bean
cF317 Coriander
cF322 Red currant
cF324 Hop (fruit cone)
cF329 Watermelon
cF333 Linseed
cF335 Lupin
cF338 Scallop
cF340 Cochineal (Carmine red, E120)
cF345 Macadamia nut
cF346 Abalone
cF347 Quinoa
CORE INDIVIDUAL ALLERGENS
cCore individual allergens, $4 each
Note: Requests for more than ve of these will exceed our allowance under Medicare
MITES (HOUSE DUST & STORAGE)
cD1 Dermatophagoides pteronyssinus
cD2 Dermatophagoides farinae
cD70 Acarus siro
cD71 Lepidoglyphus destructor
cD72 Tyrophagus putrescentiae
cD73 Glycyphagus domesticus
cD74 Euroglyphus maynei
cD201 Blomia Tropicalis
cH2 House dust
ANIMAL & AVIAN PROTEINS
cE1 Cat epithelium & dander
cE3 Horse dander
cE4 Cow dander
cE5 Dog dander
cE6 Guinea pig epithelium
cE7 Pigeon droppings
cE71 Mouse epithelium
cE73 Rat epithelium
cE77 Budgerigar droppings
cE78 Budgerigar feathers
cE79 Budgerigar serum proteins
cE81 Sheep epithelium
cE82 Rabbit epithelium
cE85 Chicken feathers
cE201 Canary bird feathers
cE213 Parrot feathers
cE215 Pigeon feathers
GRASS & GRAIN POLLENS
cG1 Sweet vernal grass
cG2 Bermuda grass
cG4 Grass pollen (Fescue)
cG5 Rye-grass
cG6 Timothy grass
cG8 Meadow grass
cG10 Johnson grass
cG11 Brome grass
cG15 Cultivated wheat
cG17 Paspalum
WEED POLLENS
cW1 Common ragweed
cW4 False ragweed
cW5 Wormwood
cW6 Mugwort
cW9 English plantain
cW10 Goosefoot (Lamb’s quarters)
cW18 Sheep sorrel
cW21 Parietaria judaica
TREE POLLENS
cT3 Birch
cT7 Oak
cT8 Elm
cT9 Olive
cT11 Sycamore, London plane
cT15 White ash
cT16 White pine
cT17 Japanese cedar
cT18 Eucalyptus
cT19 Acacia
cT21 Melaleuca
cT23 Italian cypress
cT57 Red Cedar
cT73 Australian pine
cT210 Privet pollen
MOULDS, YEASTS & TOXINS
cM1 Penicillium notatum
cM2 Cladosporium herbarum
cM3 Aspergillus fumigatus
cM4 Mucor racemosus
cM5 Candida albicans (yeast)
cM6 Alternaria alternata
cM8 Helminthosporium halodes
cM9 Fusarium moniliforme
cM10 Stemphylium botryosum
cM13 Phoma betae
cM14 Epicoccum purpurascens
cM15 Trichoderma viride
cM70 Pityrosporum orbiculare
cM80 Staphylococcus enterotoxin A
cM202 Cephalosporium acremonium
cM205 Trichophyton rubrum
cM227 Malassezia spp.
DRUGS
cC1 Penicilloyl G
cC2 Penicilloyl V
cC5 Ampicilloyl
cC6 Amoxicilloyl
cC7 Cefaclor
cC73 Insulin, human
cC74 Gelatin, bovine
VENOMS
cI1 Honey bee (Apis mellifera)
cI3 Yellow jacket (Vespula spp.
Common wasp)
cI4 Paper wasp (Polistes spp.)
cI5 Yellow hornet (Dolichovespula
arenaria)
INSECTS
cI6 Cockroach (Blatella germanica)
cI70 Fire ant (Solenopsis invicta)
cI71 Mosquito spp. (Aedes communis)
cI72 Green nimitti (Cladotanytarsus)
cI202 Grain weevil (Sitophilius granarius)
PARASITES
cP1 Ascaris
cP4 Anisakis
MISCELLANEOUS
cO1 Cotton crude bres
cO70 Seminal uid
OCCUPATIONALS
cK75 Isocyanate TDI
cK76 Isocyanate MDI
cK77 Isocyanate HDI
cK80 Formaldehyde/Formalin
cK82 Latex, Hevea braziliensis
cK84 Sunower seed
4 5
HOUSE DUST
cHX2 (H2 D1 D2 I6) Dust & Mite Mix
ANIMAL MIXES
cEX1 (E1 E3 E4 E5) Animal Mix 1 Cat dander, Horse
dander, Cow dander,
Dog dander
cEX2 (E1 E5 E6
E87 E88)
Animal Mix 2 Cat dander, Dog dander,
Guinea pig epithelium,
Rat, Mouse
cEX71 (E70 E85 E86
E89)
Feather Mix Goose feathers, Chicken
feathers, Duck feathers,
Turkey feathers
cEX72 (E78 E201
E196 E213
E214)
Bird Mix Budgerigar feathers,
Canary bird feathers,
Parakeet feathers, Parrot
feathers, Finch feathers
GRASS MIXES
cGX2 (G2 G5 G6
G8 G10 G17)
Grass Mix Bermuda grass, Rye
grass, Timothy grass,
Meadow grass, Johnson
grass, Bahia grass
TREE MIXES
cTX7 (T9 T12 T16
T18 T19 T21)
Tree Mix Olive, Willow, White Pine,
Eucalyptus, Acacia,
Melaleuca
WEED MIXES
cWX1 (W1 W6 W9
W10 W11)
Weed Mix Common ragweed,
Mugwort, English
Plantain, Goosefoot
Lamb’s Quarters,
Saltwort
cWX5 (W1 W6 W7
W8 W12)
Weed & Flower
Mix
Common ragweed,
Mugwort, Ox-eye Daisy,
Dandelion, Golden rod
MOULD MIXES
cMX2 (M1 M2 M3
M5 M6 M8)
Mould Mix Penicillium
chrysogenum,
Cladosporium herbarum,
Aspergillus fumigatus,
Candida albicans,
Alternaria alternata,
Setomelanomma
rostrata
FOOD MIXES
cFX1 (F13 F17 F18
F20 F36)
Nut Mix Peanut, Hazel nut, Brazil
nut, Almond, Coconut
cFX2 (F3 F24 F37
F40 F41)
Seafood Mix Fish, Shrimp, Blue
mussel, Tuna, Salmon
cFX3 (F4 F7 F8 F10
F11)
Cereal Mix Wheat, Oat, Maize,
Sesame seed,
Buckwheat
cFX5 (F1 F2 F3 F4
F13 F14)
Staple Food Mix Egg white, Milk, Fish,
Wheat, Peanut, Soybean
cFX15 (F33 F49 F92
F95)
Fruit Mix Orange, Apple, Banana,
Peach
cFX19 (F31 F35
F214 F244)
Vegetable Mix Carrot, Potato, Spinach,
Cucumber
cFX70 (F272 F274
F273 F275)
Spice Mix 1 Tarragon, Marjoram,
Thyme, Lovage
cFX71 (F265 RF266
F267 F268)
Spice Mix 2 Caraway, Mace,
Cardamom, Clove
cFX72 (F269 F219
F270 F271)
Spice Mix 3 Basil, Fennel seed,
Ginger, Anise
cFX73 (F26 F27 F83) Meat Mix Pork, Beef, Chicken
OCCUPATIONAL MIXES
cPAX5 (K75 K76
K77 K79)
Chemicals 1 Isocyanates (TDI, MDI,
HDI), Phthalic anhydride
cPAX6 (K78 K79
K80 K85)
Chemicals 2 Ethylene oxide,
Phthalic anhydride,
Formaldehyde,
Chloramin T
CORE ALLERGEN MIXES
cCore mixed allergens $8
Note: Requests for more than two of these will exceed our allowance under Medicare
MISCELLANEOUS
eO201 Tobacco leaf
eO202 Artemia salina sh feed
eO203 Tetramin sh feed
eO207 Daphnia sh feed
eO211 Mealworm Tenebrio mollitor
eO212 Streptavidin
GRASS & GRAIN POLLENS
eG3 Cocksfoot
eG7 Common reed
eG9 Redtop (Bentgrass)
eG12 Cultivated rye
eG13 Velvet grass
eG14 Cultivated oat
eG16 Meadow foxtail
eG70 Wild rye grass
eG71 Canary grass
eG201 Barley
eG202 Maize (Corn)
eG203 Salt grass
eG204 False oat-grass
TREE POLLENS
eT1 Box-elder
eT2 Grey alder
eT4 Hazel
eT5 American beech
eT6 Mountain juniper
eT10 Walnut
eT12 Willow
eT14 Cottonwood
eT20 Mesquite
eT22 Pecan Hickory
eT25 European ash
eT37 Bald cypress
eT41 White hickory
eT44 Hackberry
eT45 Cedar elm
eT54 Russian olive
eT55 Scotch broom
eT56 Bayberry
eT57 Red cedar
eT70 Mulberry
eT71 Red mulberry
eT72 Queen Palm
eT201 Spruce
eT203 Horse chestnut
eT205 Elder
eT206 Chestnut
eT207 Douglas r
eT208 Linden
eT209 Horn beam
eT211 Sweet gum
eT212 Cedar
eT213 Pine
eT214 Date
eT217 Peppertree
eT218 Virginia live oak
eT222 Cypress
eT223 Oil palm
WEED & CROP POLLENS
eW2 Western ragweed
eW3 Giant ragweed
eW7 Ox-eye daisy
eW8 Dandelion
eW11 Saltwort (Russian thistle)
eW12 Golden rod
eW13 Cocklebur
eW14 Common pigweed
eW15 Scale Lenscale
eW16 Rough marshelder
eW17 Firebush
eW19 Parietaria ofcinalis
eW20 Nettle
eW22 Japanese Hop
eW23 Yellow dock
eW45 Alfalfa
eW46 Dog fennel
eW82 Careless weed
eW203 Rape (Canola)
eW204 Sunower
eW206 Camomille
eW207 Lupin
eW210 Sugar-beet
DRUGS
eC8 Chlorhexidine
eC70 Insulin porcine
eC71 Insulin bovine
eC202 Suxamethonium (Succinylcholine)
eC208 Tetanus toxoid
MOULDS, YEASTS & TOXINS
eM7 Botrytis cinerea
eM11 Rhizopus nigricans
eM12 Aureobasidium pullulans
eM16 Curvularia lunata
eM36 Aspergillus terreus
eM81 Staphylococcus enterotoxin B
eM201 Tilletia tritici
eM203 Trichosporon pullulans
eM204 Ulocladium chartarum
eM207 Aspergillus niger
eM209 Penicillium frequentans
eM208 Chaetomium globosum
eM211 Trichophyton ment. var. interdigitale
eM226 Staphylococcus enterotoxin TSST
eM223 Staphylococcus enterotoxin C
eM228 Aspergillus avus
OCCUPATIONALS
eK70 Green coffee bean
eK71 Castor bean
eK72 Ispaghula
eK73 Silk waste
eK74 Silk
eK78 Ethylene oxide
eK79 Phthalic anhydride
eK81 Ficus spp.
eK83 Cotton seed
eK85 Chloramin T
eK86 Trimellitic Anhydride (TMA)
eK87 Alpha-amylase
eK201 Papain
eK202 Bromelin
eK203 Phosphlipase
eK204 Maxatase
eK205 Alkalase
eK206 Savinase
eK208 Lysozyme
eK209 Hexahydrophtalic anhydrid
eK211 MTHP Anhydrid
eK212 Abachi wood dust
eK213 Pepsin
eK214 Bougainvillea spp.
VENOMS
eI2 White-faced hornet (Dolichovespula
maculata)
eI77 European paper wasp (Polistes
dominulus)
eI75 European Hornet (Vespa crabro)
eI205 Bumblebee
INSECTS
eI8 Moth
eI73 Blood worm
eI76 Berlin beetle
eI201 Horse bot y
eI203 Mediterranean Flour Moth
eI204 Horse y
eI206 Cockroach, American
eI207 Cockroach, Oriental
ESOTERIC INDIVIDUAL ALLERGENS
eEsoteric individual allergens, $12 each
Note: Requests for more than one of these will exceed our allowance under Medicare.
Some esoteric allergen results may take up to ve weeks
ESOTERIC INDIVIDUAL ALLERGENS
eEsoteric individual allergens, $12 each
Note: Requests for more than one of these will exceed our allowance under Medicare.
Some esoteric allergen results may take up to ve weeks
MITES (HOUSE DUST & STORAGE)
eD3 Dermatophagoides microceras
ANIMAL & AVIAN PROTEINS
eE70 Goose feathers
eE72 Mouse urine proteins
eE74 Rat urine proteins
eE75 Rat serum proteins
eE76 Mouse serum proteins
eE80 Goat epithelium
eE83 Swine epithelium
eE84 Hamster epithelium
eE86 Duck feathers
eE87 Rat epithelium, serum & urine
proteins
eE88 Mouse epithelium, serum & urine
proteins
eE89 Turkey feathers
eE196 Parakeet feathers
eE197 Parakeet droppings
eE198 Parakeet serum
eE199 Canary bird serum
eE200 Canary bird droppings
eE202 Reindeer epithelium
eE203 Mink epithelium
eE204 BSA (bovine serum albumin)
eE205 Horse serum proteins
eE206 Rabbit serum proteins
eE208 Chinchilla epithelium
eE209 Gerbil epithelium
eE210 Fox epithelium
eE211 Rabbit urine proteins
eE214 Finch feathers
eE216 Deer epithelium
eE217 Ferret epithelium
eE218 Chicken droppings
eE219 Chicken serum proteins
eE220 Cat serum albumin
eE221 Dog serum albumin
eE222 Swine serum albumin
PARASITES
eP2 Echinococcus
6 7
ESOTERIC INDIVIDUAL FOOD ALLERGENS
eEsoteric individual food allergens, $12 each
Note: Requests for more than one of these will exceed our allowance under Medicare.
Some esoteric allergen results may take up to ve weeks
FOOD
eF42 Haddock
eF50 Chub (mackerel)
eF51 Bamboo shoot
eF54 Sweet potato
eF55 Common millet
eF56 Foxtail millet
eF57 Japanese millet
eF58 Pacic squid
eF60 Jack mackerel (Scad)
eF61 Sardine (Japanese) Pilchard
eF124 Spelt wheat
eF147 Gulf ounder
eF182 Lima bean
eF205 Herring
eF206 Mackerel
eF213 Rabbit meat
eF217 Brussel sprouts
eF219 Fennel seed
eF227 Sugar-beet seed
eF231 Milk boiled
eF234 Vanilla
eF236 Cow’s whey
eF245 Egg
eF246 Guar, guar gum (E412)
eF254 Plaice
eF264 Eel
eF265 Caraway
eF266 Mace
eF268 Clove
eF269 Basil
eF271 Anise
eF272 Tarragon
eF273 Thyme
eF274 Marjoram
eF275 Lovage
eF276 Fennel fresh
eF277 Dill
eF278 Bay leaf
eF283 Oregano
eF285 Elk-Moose meat
eF286 Mare’s Milk
eF288 Blueberry
eF289 Date
eF292 Guava
eF295 Carambola
eF296 Carob (E410)
eF297 Gum arabic (E414)
eF298 Tragacanth (E413)
eF301 Persimmon
eF303 Halibut
eF304 Langust (spiny lobster)
eF305 Fenugreek
eF306 Lime
eF307 Hake
eF308 Sardine(Pilchard)
eF310 Blue vetch
eF311 Megrim
eF312 Swordsh
eF313 Anchovy
eF314 Snail
eF316 Rape (Canola) seed
eF318 Jack fruit
eF319 Beetroot
eF320 Craysh
eF321 Horse meat
eF323 Conalbumin
eF325 Sheep milk
eF326 Sheep whey
eF328 Fig
eF330 Rose hip
eF331 Saffron
eF332 Mint
eF334 Bovine lactoferrin
eF336 Jujube
eF337 Sole
eF339 Allspice
eF342 Olive (black fresh)
eF343 Raspberry
eF344 Sage
eF348 Lychee
eF369 Catsh
eF381 Red Snapper
eF384 Whitesh
eF410 Grouper
eF412 Orange roughy
eF413 Pollock
eF414 Tilapia
eF415 Walleye pike
eRX3 (G2 G5 G17
W1 W9 W10)
Inhalant 3 Bermuda grass, Rye
grass, Bahia grass,
Common Ragweed,
English Plantain,
Goosefoot Lamb’s
Quarters
eRX4 (G2 G5 G1
W1 W6 W9)
Inhalant 4 Sweet Vernals grass,
Bermuda grass, Rye
grass, Common
Ragweed, Mugwort,
English Plantain,
eRX5 (D1 E1 M3 I6) Inhalant 5 Dermatophagoides
pteronyssinus, Cat
dander, Aspergillus
fumigatus, Cockroach
eRX6 (T3 G6 W6
M2 M6)
Inhalant 6 Birch, Timothy grass,
Mugwort, Cladosporium,
Alternaria alternata
eRX7 (D1 E1 E3 E5
E82)
Inhalant 7 Dermatophagoides
pteronyssinus, Cat
dander, Horse dander,
Dog dander, Rabbit
epithelium
TREE MIXES
eTX1 (T1 T3 T7 T8
T10)
Tree Mix 1 Box elder, Birch, Oak,
Elm, Walnut
eTX2 (T1 T7 T8
T14 T22)
Tree Mix 2 Box elder, Oak, Elm,
Cottonwood, Pecan
Hickory
eTX3 (T6 T7 T8
T14 T20)
Tree Mix 3 Mountain Juniper, Oak,
Elm, Cottonwood,
Mesquite
eTX4 (T7 T8 T11
T12 T14)
Tree Mix 4 Oak, Elm, Sycamore,
Willow, Cotttonwood
eTX5 (T2 T4 T8
T12 T14)
Tree Mix 5 Grey Alder, Hazel, Elm,
Willow, Cottonwood
eTX6 (T1 T3 T5 T7
T10)
Tree Mix 6 Box elder, Birch,
American Beech, Oak,
Walnut
eTX8 (T1 T3 T4 T7
T11)
Tree Mix 8 Box elder, Birch, Hazel,
Oak, Sycamore
eTX9 (T2 T3 T4 T7
T12)
Tree Mix 9 Grey Alder, Birch, Hazel,
Oak, Willow
eTX10 (T2 T3 T4
T15)
Tree Mix 10 Grey Alder, Birch,White
Ash
WEED MIXES
eWX2 (W2 W6 W9
W10 W15)
Weed Mix 2 Western ragweed,
Mugwort, English
Plantain, Goosefoot
Lamb’s Quarters, Scale
Lenscale
eWX3 (W6 W9 W10
W12 W20)
Weed Mix 3 Mugwort, English
Plantain, Goosefoot
Lamb’s Quarters, Golden
rod, Nettle
eWX6 (W9 W10
W11 W18)
Weed Mix 6 English Plantain,
Goosefoot Lamb’s
Quarters, Saltwort
Russian Thistle, Sheep
sorrel
eWX7 (W7 W8 W9
W10 W12)
Weed Mix 7 Ox-eye Daisy, Dandelion,
English Plantain,
Goosefoot Lamb’s
Quarters, Golden rod
eWX209 (W1 W2 W3) Weed Mix 209 Common ragweed,
Western ragweed, Giant
ragweed
MOULD MIXES
eMX1 (M1 M2 M3
M6)
Mould Mix 1 Penicillium chrysogenum,
Cladosporium herbarum,
Aspergillus fumigatus,
Alternaria alternata
eMX4 (M3 M207
M36 M228)
Mould Mix 4 A. fumigatus, A. niger, A.
terreus, A. avus
FOOD MIXES
eFX7 (F25 F45 F47
F48 F85)
Food Mix 7 Tomato, Yeast, Garlic,
Onion, Celery
eFX8 (F17 F18 F33
F49 F93)
Food Mix 8 Hazel nut, Brazil nut,
Orange, Apple, Cacao
eFX9 (F20 F84 F87
F92 F259)
Food Mix 9 Almond, Kiwi, Melons,
Banana, Grape
eFX10 (F26 F27 F75
F83 F284)
Food Mix 10 Pork, Beef, Egg yolk,
Chicken, Turkey
eFX11 (F8 F12 F15
F31 F260)
Food Mix 11 Maize, Pea, White
bean, Carrot, Broccoli
eFX12 (F5 F9 F35
F225 RF212)
Food Mix 12 Rye, Rice, Potato,
Mushroom, Pumpkin
eFX13 (F12 F15 F31
F35)
Food Mix 13 Pea, White bean,
Carrot, Potato
eFX14 (F25 F214 F216
F218)
Food Mix 14 Tomato, Spinach,
Cabbage, Paprika
eFX16 (F44 F94 F208
F210)
Food Mix 16 Strawberrry, Pear,
Lemon, Pineapple
eFX17 (F49 F92 F94
F95)
Food Mix 17 Apple, Banana, Pear,
Peach
eFX18 (F12 F13 F14) Food Mix 18 Pea, Peanut, Soybean
eFX20 (F4 F5 F6 F9) Food Mix 20 Wheat, Rye, Barley,
Rice
eFX21 (F84 F87 F92
F95 F210)
Food Mix 21 Kiwi fruit, Melon,
Banana, Peach,
Pineapple
eFX22 (F201 F202
F203 F256)
Food Mix 22 Pecan nut, Cashew
nut, Pistachio, Walnut
eFX23 (F26 F27 F83
F284)
Food Mix 23 Pork, Beef, Chicken
meat, Turkey meat
eFX24 (F17 F24 F84
F92)
Food Mix 24 Hazel nut, Shrimp, Kiwi
fruit, Banana
eFX25 (F10 F45 F47
F85)
Food Mix 25 Sesame seed, Yeast,
Garlic, Celery
eFX26 (F1 F2 F13 F89) Food Mix 26 Egg white, Cow’s milk,
Peanut, Mustard
eFX27 (F3 F4 F14 F17) Food Mix 27 Fish (cod), Wheat,
Soybean, Hazel nut
eFX28 (F10 F24 F27
F84)
Food Mix 28 Sesame seed, Shrimp,
Beef, Kiwi
eFX29 (F33 F208 F209
F302)
Food Mix 29 Orange, Lemon,
Grapefruit, Mandarin
eFX30 (F84 F91 F92
F293)
Food Mix 30 Kiwi, Mango, Banana,
Avocado, Papaya
eFX31 (F49 F94 F95
F242 F255)
Food Mix 31 Apple, Pear, Peach,
Cherry, Plum
eFX32 (F235 F12 F15
RF296)
Food Mix 32 Lentil, Pea, White
bean, Carob
eFX74 (F3 F205 F206
F254)
Food Mix 74 Cod, Herring,
Mackerel, Plaice
OCCUPATIONAL MIXES
ePAX1 (E3 E4 E70
E85)
Horse & Cow dander,
Goose & Chicken
feathers
ePAX3 (M3 M6 G12
G15)
Aspergillus, Alternaria,
Wheat & Rye pollen
ePAX4 (F4 F14 K87
I202)
Wheat & Soy our,
alpha-amylase,
Sitophilus granarius
ESOTERIC ALLERGEN MIXES
eEsoteric mixed allergens $12 each
Note: Requests for more than one of these will exceed our allowance under Medicare.
Some esoteric allergen results may take up to ve weeks
ESOTERIC ALLERGEN MIXES
eEsoteric mixed allergens $12 each
Note: Requests for more than one of these will exceed our allowance under Medicare.
Some esoteric allergen results may take up to ve weeks
ANIMAL MIXES
eEX70 (E6 E82 E84
E87 E88)
Animal Mix 3 Guinea pig epithelium,
Rabbit epithelium,
Hamster epithelium, Rat,
Mouse
eEX73 (E70 E85 E86
E213)
Animal Mix 4 Goose feathers, Chicken
feathers, Duck feathers,
Parrot feathers
GRASS MIXES
eGX1 (G3 G4 G5
G6 G8)
Grass Mix 1 Cocksfoot, Meadow
Fescue, Rye grass,
Timothy grass, Meadow
grass
eGX3 (G1 G5 G6
G12 G13)
Grass Mix 3 Sweet Vernal grass, Rye
grass, Timothy grass,
Cultivated Rye, Velvet
grass
eGX4 (G1 G5 G7
G12 G13)
Grass Mix 4 Sweet Vernal grass, Rye
grass, Common reed,
Cultivated rye,Velvet
grass
eGX6 (G2 G5 G10
G11 G13
G17)
Grass Mix 6 Bermuda grass, Rye
grass, Johnson grass,
Brome grass, Velvet
grass, Bahia grass
COMBINATION INHALANT MIXES
eRX1 (G6 W6 W9
W21 T3)
Inhalant 1 Timothy grass, Mugwort,
English Plantain,
Parietaria, Birch
eRX2 (D2 E1 E3 E5
M6)
Inhalant 2 Dermatophagoides
farinae, Cat dander,
Horse dander, Dog
dander, Alternaria
alternata
8 9
RECOMBINANT AND NATIVE INDIVIDUAL ALLERGEN MOLECULES
nIndividual Native (n) $40 each
rRecombinant (r) allergen molecules $40 each
ANIMALS
rE94 rFel d1 (recombinant cat)
rE220 nFel d 2 Cat serum albumin Felis
domesticus
rE101 rCan f1 (recombinant dog)
rE102 rCan f2 (recombinant dog)
nE221 nCan f 3 Dog serum albumin
Canis familiaris
nE204 nBos d 6 BSA, Cow Bos spp.
nE222 nSus s Pig serum albumin, Swine
Sus scrofa
GRASSES
rG205 rPhl p 1 (recombinant timothy)
rG206 rPhl p 2 (recombinant timothy)
rG208 rPhl p 4 (native timothy)
rG209 rPhl p 6 (recombinant timothy)
rG210 rPhl p 7 (recombinant timothy)
rG211 rPhl p 11 (recombinant timothy)
rG212 rPhl p 12 (recombinant timothy)
rG213 rPhl p1; rPhl p5b (recombinant
timothy)
rG214 rPhl p7;rPhl p12 (recombinant
timothy)
rG215 rPhl p 5b (recombinant timothy)
n G216 nCyn d 1 Bermuda grass,
Cynodon dactylon
FOODS
cF76 nBos d 4 a-lactalbumin, Milk Bos
spp.
cF77 nBos d 5 b-lactoglobulin, Milk
Bos spp.
cF78 nBos d 8 Casein, Milk Bos spp.
cCore individual allergens, $4 each
Note: These allergens are priced as core
individual allergens ($4 ea)
FOODS
nF232 nGal d 2 Ovalbumin, Egg Gallus
spp.
nF233 nGal d 1 Ovomucoid, Egg Gallus
spp.
nF323 nGal d 3 Conalbumin, Egg Gallus
spp.
nF334 nBos d Lactoferrin, Milk Bos spp.
rF351 rPen a 1 Tropomyosin, Shrimp
Penaeus aztecus
rF353 rGly m 4 PR-10, Soy Glycine
rF354 rBer e 1 Brazil nut, Bertholletia
excelsa
rF355 rCyp c 1 Carp Cyprinus carpio
rF417 rApi g 1.01 PR-10, Celery Apium
graveolens
rF418 rApi g 1.02 (recombinant Celery)
rF419 rPru p 1 PR-10, Peach Prunus
persica
rF420 rPru p 3 LTP, Peach Prunus
persica
rF421 rPru p 4 Prolin, Peach Prunus
persica
rF416 rTri a 19 Omega-5 Gliadin, Wheat
Triticum spp
rF422 rAra h 1 Peanut Arachis hypogaea
rF423 rAra h 2 Peanut Arachis hypogaea
rF424 rAra h 3 Peanut Arachis hypogaea
rF352 rAra h 8 PR-10, Peanut Arachis
hypogaea
rF427 rAra h 9 LTP, Peanut Arachis
hypogaea
rF425 rCor a 8 LTP, Hazel nut Corylus
avellana
rF426 rGad c 1 Cod Gadus morhua
rF428 rCor a 1 PR-10, Hazel nut Corylus
avellana
TREES
rT215 rBet v 1 PR-10, Birch Betula
verrucosa
rT216 rBet v 2 Prolin, Birch Betula
verrucosa
rT220 rBet v 4, Birch Betula verrucosa
rT221 rBet v 2, rBet v 4 Birch Betula
verrucosa
rT225 rBet v 6 Birch Betula verrucosa
nT224 nOle e 1 Olive Olea europaea
WEEDS
rW211 rPar j 2 (recombinant parietaria)
nW230 nAmb a 1, Ragweed Ambrosia
elatior
nW231 nArt v 1, Mugwort Artemisia
vulgaris
MOULDS
rM218 rAsp f1 (recombinant aspergillus)
rM219 rAsp f2 (recombinant aspergillus)
rM220 rAsp f 3 (recombinant aspergillus)
rM221 rAsp f4 (recombinant aspergillus)
rM222 rAsp f6 (recombinant aspergillus)
rM229 rAlt a 1 (component alternaria)
LATEX
rK215 rHev b 1, Latex Hevea brasiliensis
rK217 rHev b 3, Latex Hevea brasiliensis
rK218 rHev b 5, Latex Hevea brasiliensis
rK219 rHev b 6.01, Latex Hevea
brasiliensis
rK220 rHev b 6.02, Latex Hevea
brasiliensis
rK221 rHev b 8, Prolin, Latex Hevea
brasiliensis
rK222 rHev b 9, Latex Hevea brasiliensis
rK224 rHev b 11, Latex Hevea
brasiliensis
VENOM
nK203 nApi m 1, Phospholipase A2, Bee
Apis mellifera
OCCUPATIONAL ALLERGENS
nK205 Alkalase, Bacillus spp.
nK87 nAsp o 1, a-amylase Aspergillus
oryzae
nK201 nCar p 1, Papain, Papaya Carica
papaya
nK208 nGal d 4, Lysozyme, Egg Gallus
spp.
nK204 Maxatase, Bacillus licheniformis
nK206 Savinase, Bacillus spp.
nK213 nSus s Pepsin, Swine Sus scrofa
OTHERS (to exclude CCD reactivity)
nRo214 MUXF3 CCD, Bromelin
nK202 nAna c 2 Bromelin, Pineapple
Ananas comosus
ImmunoCAP ISAC® ($350 per profile)
The ISAC (Immuno Solid-phase Allergen Chip) is a microarray system developed by VBC Genomics and Phadia. ISAC can now allow laboratories
to reliably and simultaneously determine specic IgE levels to a wide range of clinically important individual allergen molecules more economically
than using many individual recombinant CAP allergens.
Clinical studies have shown that, for example, even modest levels of serum specic IgE level to ara h 2, one of the nine major peanut allergens,
are strongly predictive of more severe reactions and poor tolerance of oral challenges. Similarly, modest levels of serum specic IgE to ovomucoid,
an egg allergen which is heat resistant, are strongly predictive of poor tolerance to even cooked egg in a baked cake; the rst challenge usually
used by allergy clinics when one is condent that a child might be starting to lose their egg allergy.
The ISAC proles are performed in batches, and the results are reported semi-quantitatively and organised into both the individual allergen
molecule source, as well as the protein group from which it comes. These protein groups have particular patterns of clinical signicance. For
example, specic IgE to Lipid Transfer Proteins are often associated with systemic and more severe reactions in addition to oral allergy symptoms
and these molecules are usually not altered with food preparation and cooking (enzyme digestion and heat). Similarly, seed storage proteins
are also heat resistant and often associated with signicant symptoms with cooked foods. In contrast, PR-10 proteins are heat labile and are
associated with oral allergy symptoms with the raw, rather than cooked foods. Similarly, heat sensitive prolin proteins are more associated
with nuisance rather than severe symptoms. Tropomyosin proteins account for dustmite-crustacean cross-reactivity. Animal albumins and sh
parvalbumins are important causes of other food reactions.
A table of the allergens included in the ISAC prole is shown opposite.
ImmunoCAP ISAC® Allergen Components
Allergen
Component Allergen Source Protein Group
COMMON
NAME LATIN NAME
PLANTS
nCyn d 1 Bermuda grass Cynodon dactylon Grass group 1
rPhl p 1 Timothy Phleum pratense Grass group 1
rPhl p 2 Timothy Phleum pratense Grass group 2
nPhl p 4 Timothy Phleum pratense
rPhl p 5 Timothy Phleum pratense Grass group 5
rPhl p 6 Timothy Phleum pratense
rPhl p 11 Timothy Phleum pratense
rBet v 1 Birch Betula verrucosa PR-10 protein
rAln g 1 Alder Alnus glutinosa PR-10 protein
rCor a 1.0101 Hazel pollen Corylus avellana PR-10 protein
nCry j 1 Japanese ceder Cryptomeria japonica
nCup a 1 Cypress Cupressus arizonica
nOle e 1 Olive Olea europaea
rPla a 1 Plane tree Platanus acerifolia
nPla a 2 Plane tree Platanus acerifolia
nAmb a 1 Ragweed Ambrosia artemisiifolia
nArt v 1 Mugwort Artemisia vulgaris
nArt v 3 Mugwort Artemisia vulgaris Lipid transfer protein (nsLTP)
rPar j 2 Wall pellitory Parietaria Judaica Lipid transfer protein (nsLTP)
nSal k 1 Saltwort Salsola kali
nAct d 1 Kiwi Actinidia deliciosa
nAct d 2 Kiwi Actinidia deliciosa
nAct d 5 Kiwi Actinidia deliciosa
nAct d 8 Kiwi Actinidia deliciosa PR-10 protein
rApi g 1 Celery Apium graveolens PR-10 protein
rDau c 1 Carrot Daucus carota PR-10 protein
rMal d 1 Apple Malus domestica PR-10 protein
rPru p 1 Peach Prunus persica PR-10 protein
nPru p 3 Peach Prunus persica Lipid transfer protein (nsLTP)
rAna o 2 Cashew nut Anacardium occidentale
nAra h 1 Peanut Arachis hypogaea Storage protein, vicilin
nAra h 2 Peanut Arachis hypogaea Storage protein, Conglutin
nAra h 3 Peanut Arachis hypogaea Storage protein, 11S globulin
rAra h 8 Peanut Arachis hypogaea PR-10 protein
rBer e 1 Brazil nut Bertholletia excelsa Storage protein, 2S albumin
rCor a 1.0401 Hazelnut Corylus avellana PR-10 protein
rCor a 8 Hazelnut Corylus avellana Lipid transfer protein (nsLTP)
nCor a 9 Hazelnut Corylus avellana Storage protein, 11S globulin
rGly m 4 Soybean Glycine max PR-10 protein
nGly m 5 Soybean Glycine max Storage protein, b-conglycinin
nGly m 6 Soybean Glycine max Storage protein, glycinin
nSes i 1 Sesame seed Sesamum indicum Storage protein, 2S albumin
nTri a 18 Wheat Triticum aestivum
nTri a gliadin Wheat Triticum aestivum Crude gliadin
rTri a 19.0101 Wheat Triticum aestivum Omega-5 gliadin
nTri a aA_TI Wheat Triticum aestivum
rHev b 1 Latex Hevea brasiliensis
rHev b 3 Latex Hevea brasiliensis
rHev b 5 Latex Hevea brasiliensis
rHev b 6 Latex Hevea brasiliensis
CROSS REACTIVE MARKERS, PLANTS
rBet v 4 Birch Betula verrucosa Calcium binding protein,
Polcalcin
rPhl p 7 Timothy Phleum pratense Calcium binding protein,
Polcalcin
rBet v 2 Birch Betula verrucosa Profilin
rHev b 8 Latex Hevea brasiliensis Profilin
rMer a 1 Annual mercury Mercurialis annua Profilin
nOle e 2 Olive Olea europaea Profilin
rPhl p 12 Timothy Phleum pratense Profilin
nAna c 2 Bromelain Ananas comosus CCD marker
ImmunoCAP ISAC® Allergen Components
Allergen
Component Allergen Source Protein Group
COMMON
NAME LATIN NAME
NON-PLANTS
nBos d 6 BSA Bos domesticus Serum albumin
nBos d 8 Cow’s milk Bos domesticus Caseins
nBos d lactoferrin Bos domesticus Laktoferrin
nGal d 1 Egg Gallus domesticus Ovomucoid
nGal d 2 Egg Gallus domesticus Ovalbumin
nGal d 3 Egg Gallus domesticus Conalbumin
nGal d 5 CSA (Livetin) Gallus domesticus Serum albumin
rCyp c 1 Carp Cyprinus carpio Parvalbumin
rGad c 1 Cod Gadus callarias Parvalbumin
rDer f 1 House dust
mite
Dermatophagoides
farinae
rDer f 2 House dust
mite
Dermatophagoides
farinae
nDer p 1 House dust
mite
Dermatophagoides
pteronyssinus
nDer p 2 House dust
mite
Dermatophagoides
pteronyssinus
rEur m 2 Storage mite Euroglyphus maynei
rCan f 1 Dog Canis familiaris Lipocalin
rCan f 2 Dog Canis familiaris Lipocalin
nCan f 3 Dog Canis familiaris Serum albumin
nEqu c 3 Horse Equus caballus Serum albumin
rFel d 1 Cat Felis domesticus Uteroglobin
nFel d 2 Cat Felis domesticus Serum albumin
nMus m 1 Mouse Mus musculus Lipocalin
rAlt a 1 Alternaria Alternaria alternata
rAlt a 6 Alternaria Alternaria alternata
rAsp f 1 Aspergillus Aspergillus fumigatus
rAsp f 2 Aspergillus Aspergillus fumigatus
rAsp f 3 Aspergillus Aspergillus fumigatus
rAsp f 4 Aspergillus Aspergillus fumigatus
rAsp f 6 Aspergillus Aspergillus fumigatus
rCla h 8 Cladosporium Cladosporium
herbarum
nApi m 1 Honey bee
venom Apis mellifera Phospholipase A2
nApi m 4 Honey bee
venom Apis mellifera Melittin
rBla g 1 Cockroach Blattella germanica
rBla g 2 Cockroach Blattella germanica
rBla g 4 Cockroach Blattella germanica
rBla g 5 Cockroach Blattella germanica
rAni s 1 Anisakis Anisakis simplex
CROSS REACTIVE MARKERS, NON-PLANTS
rAni s 3 Anisakis Anisakis simplex Tropomyosin
nBla g 7 Cockroach Blattella germanica Tropomyosin
rDer p 10 House dust
mite
Dermatophagoides
pteronyssinus Tropomyosin
rPen a 1 Shrimp Penaeus aztecus Tropomyosin
nPen i 1 Shrimp Penaeus indicus Tropomyosin
nPen m 1 Shrimp Penaeus monodon Tropomyosin
10 11
For further information regarding allergy testing please contact Dr Karl Baumgart,
Director of Immunology on (02) 98 555 286 or email kbaumgart@dhm.com.au
14 GIFFNOCK AVENUE • MACQUARIE PARK • NSW 2113 • AUSTRALIA
TEL (02) 98 555 222 • (02) FAX 9878 5077
MAIL ADDRESS • LOCKED BAG 145 • NORTH RYDE • NSW 1670 • AUSTRALIA
DOUGLASS HANLY MOIR PATHOLOGY • ABN 80 003 332 858
A subsidiary of SONIC HEALTHCARE
31 LAWSON STREET • PENRITH • NSW 2750 • AUSTRALIA
TEL (02) 4734 6500 • FAX (02) 4732 2503
MAIL ADDRESS • PO BOX 443 • PENRITH • NSW 2751 • AUSTRALIA
BARRATT & SMITH PATHOLOGY • ABN 80 003 332 858
A trading name of DOUGLASS HANLY MOIR PATHOLOGY
A subsidiary of SONIC HEALTHCARE
DHMP/B&S-AV2-2010-Brochure
BILLING POLICY FOR ALLERGY TESTING
Our policy is to respect your request for the allergens and decode them according to our best practice. If you have requested
more allergens than our allowance under Medicare, we will bill your patient according to the pricing in this menu. If you have
nominated the patient to be bulk-billed or if the patient has signed a Medicare assignment form, this billing policy will still apply
for all tests above our allowance under Medicare.
You will see in our Allergy menu that we now list a price for each allergen reagent and that this is organised into different allergen
classes. Core individual allergens are $4, core mixed allergens are $8, esoteric individual allergens are $12 and esoteric mixed
allergens are also $12. Our highly specialised recombinant (r) or native (n) individual allergen molecules are $40, and the ISAC
prole, which tests 103 different individual allergen molecules from 47 different allergens, is $350.
If the price of the allergens requested is more than the Medicare rebate of $22.95, the laboratory will not accept bulk-billing
for the request and the patient will be billed according to the price on the menu and may claim a rebate, subject to coning.
Practically, this means we will not accept a bulk-billed request for more than ve core individual allergens, or two core mixed
allergens, or more than one esoteric individual or mixed allergens. However, one core mixed allergen plus three core individual
allergens would be covered by the Medicare rebate. Similarly, two core mixed allergens plus one core individual allergen would
be covered under our allowance under Medicare. One esoteric mixed or individual allergen plus two core individual allergens or
one core mixed allergen would be covered under our allowance under Medicare. A simple table summarises this for you and
your patients.
Please note that eligible patients may be able to claim a rebate on four occasions per year for testing
performed on separately collected blood, with each episode at least 14 days apart.
WHAT CAN YOU ORDER THAT IS MEDICARE REBATABLE?
Our Fee For Different Allergen Types
Core individual $4
Core mix $8
Esoteric Individual $12
Esoteric Mix $12
Recombinant/ Native $40
Medicare Rebatable Private Bill
Combinations beyond the black line will be privately billed but patients may be eligible for a Medicare rebate of $22.95.
Printed on re-cycled paper
