Leica ISH User Manual To The 7a52d343 Fd5e 431a 9fc4 541efd96bf3f
User Manual: Leica ISH to the manual
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Leica BOND RX
– Fully Automated IHC & ISH
Quality. Speed. Flexibility.
Research Use Only. Not for use in diagnostic procedures.
Choose the ideal reagents
There are no limits to the reagents
you can use on the truly open
Leica BOND RX . Freely select
Novocastra BOND reagents
or any other antibody, probe
or detection component.
•Novocastra BOND reagents
•Novocastra manual reagents
Total Freedom
Create a total research solution
Because researchers need specialized
instruments and consumables,
Leica Biosystems supports you with
research-specific histology and
microscopy systems including:
•Cryostats and microtomes
•Microscopes
•Scanning and imaging solutions
Total Research
Receive unrivalled support
Call Leica Biosystems’ IHC and
ISH research experts for help with
instrument setup, applications
knowledge and responsive service.
•Training and protocol development
•Applications advice
•Flexible maintenance contracts
Total Assistance
Quality
Clarity that enhances insight
Speed
More slides, more opportunities
Flexibility
The freedom of open research
Leica BOND RX is part of a complete research
solution that gives you the freedom to discover.
Leica BOND RX
With over 12 million people diagnosed
with cancer every year*, new insights
that lead to better treatments will
significantly improve many lives.
The answers are there to be
discovered if the barriers to innovation
are removed.
You need the flexibility to explore new
possibilities, clear results to ensure
nothing is missed and rapid,
cost-effective systems that let you
perform more tests.
Clear the path to discovery and
life-changing breakthroughs become
closer than ever before.
* GLOBOCAN 2008
Cancer Incidence and Mortality Worldwide in 2008
Leica BOND RX
Research Use Only. Not for use in diagnostic procedures.
Choose Novocastra BOND reagents to
make it easier to deliver high-quality
staining. Specifically developed for
Leica BOND using Leica’s in-house
Novocastra staining science,
these pre-optimized reagents
deliver exceptional performance
with minimal preparation.
No matter what reagents you choose,
the fully automated Leica BOND RX
will standardize your staining to
remove process variation and
deliver unrelenting consistency.
Leica BOND RX provides full onboard
IHC and ISH automation with both
Leica and laboratory protocols.
Protect valuable tissue. The unique
Leica BOND Covertile™ system
provides the utmost care for valuable
specimens. Unlike other automated
stainers, Leica BOND has very gentle
reagent application and incubation
protection that minimizes the potential
for tissue damage and costly repeats.
Clarity and Accuracy Complete Consistency Total Tissue Care
Make sure you see the whole picture. Leica BOND RX consistently provides the high-quality
results that let you clearly analyze every stain so vital information is not overlooked, and
every section gets you one step closer to new insights.
QUALITY
Leica BOND RX
Research Use Only. Not for use in diagnostic procedures.
Finish slides earlier. Leica BOND RX
is 50% faster than previous
generation stainers. So you can
process more slides in a day,
gain a rapid understanding of the
possibilities of your latest trials, and
reach critical answers sooner.
Faster
Your work flows when you are
both flexible and organized. With
three independent slide trays, each
Leica BOND RX is effectively three
stainers in one instrument. So you
have the flexibility of continuous
processing while keeping your
slides together to reduce sorting.
Continuous
As your research program grows, so
does Leica BOND. With the ability
to connect up to five Leica BOND RX
instruments to a single data collection
point, you are free to expand capacity
so your research never slows down.
Ready for More
Find answers sooner. With speed and organization, Leica BOND RX lets you stain more
slides daily. This gives you the freedom to explore more possibilities, test more theories,
and make that critical breakthrough sooner.
SPEED
Leica BOND RX
Research Use Only. Not for use in diagnostic procedures.
Always use the antibodies, probes
and detection components that best
suit your research. Leica BOND RX
is a truly open system so you are
free to choose the reagents that
provide the most accurate results in
in the most cost-effective manner.
Truly Open
You are free to explore with the
easy-to-use Leica BOND RX software.
You can use Leica protocols for
pre-defined consistency, or freely
create your own custom protocols
when your research calls for
something special. New insights
require innovative thinking and with
Leica BOND RX you’re not locked
into conventional methods.
Fully Flexible
Control costs and do more
research with your existing budget.
Leica BOND RX requires virtually
no daily maintenance and has
extremely small reagent dispense
volumes so you can spend less time
and money on overheads, and more
on making critical discoveries.
Cost Effective
Eliminate barriers to discovery. Important research should never be held up by mandated
reagents. So Leica BOND RX has truly open reagents and allows protocol customization.
With Leica BOND RX dispensing your reagents in the sequence you choose, you are free
to uncover scientific breakthroughs faster, and more cost-efficiently.
FLEXIBILITY
Leica BOND RX
Research Use Only. Not for use in diagnostic procedures.
4. Continuous Processing
Leica BOND RX is effectively
three independent stainers in one
instrument - the ideal balance
of flexibility and organization.
2. Custom Protocols
Control dispense sequences,
incubation times and temperature
settings with the Leica BOND RX
protocol editor. This flexibility,
along with open reagents, gives
you complete freedom over your
IHC and ISH staining.
1. Open Reagents
Leica BOND RX open containers
make loading and running your
reagents easy and cost-effective.
This truly open system lets you
choose antibodies, probes and
detection components from any
source.
Flexibility
3. Covertile Technology
Unlike other systems,
Leica BOND RX is gentle on the
tissue and ensures total tissue
care with exceptionally low
dispense and waste volumes.
Quality
System Specifications
Dimensions 775 mm (W) x 1359 mm (H) x 785 mm (D)
30.5 in (W) x 53.5 in (H) x 30.9 in (D)
Weight (dry) 246 kg
542 lb.
Slide capacity 30 slides
Finished trays (10 slides) may be replaced
continuously
Reagent container capacity 7 mL and 30 mL
Number of reagent containers 36 reagents
Bulk reagent container capacity 2 L or 5 L
Hazardous waste container capacity 5 L
Standard waste container capacity 2 x 5 L
Operating voltage 100 to 240 V~
Mains frequency 50/60 Hz
Power consumption 1200 VA
Maximum operating temperature 35 °C (95 °F)
Minimum operating temperature 5 °C (41 °F)
Temperature required to meet 18–26 °C (64–79 °F)
staining performance requirements
Operating humidity (noncondensing) 10 to 80% RH
Operating altitude 0 to 1600 m (5250 ft.) above sea level
Sound pressure level output (at 1 m) < 85 dBA maximum
< 65 dBA normal operation
5
2
3
4
1
5. Parallel Automation
Inside Leica BOND RX there
are four very active robots
simultaneously moving, dispensing
and ensuring high throughput and
rapid turnaround.
Speed
Leica BOND RX
Research Use Only. Not for use in diagnostic procedures.
TOTAL HISTOLOGY SOLUTIONS
High-quality IHC and ISH staining depends upon expert tissue preparation
and sectioning. With a broad range of histology instruments, consumables
and applications knowledge, Leica Biosystems offers research-specific
histology solutions that will help you efficiently prepare high-quality
sections for advanced staining.
· Tissue preparation
· Sample identification and tracking
· Tissue processors, cassettes and paraffin wax
· Embedding centers, accessories and paraffin wax
· Microtomes, blades and slides
· Coverslippers, mountants and coverslips
· Microscopy and imaging solutions
· Expert service and support
· Ongoing maintenance support
Use your smart phone to find out
more about Leica BOND RX .
Download the free mobile app at
http://gettag.mobi, then scan this tag.
LEICA BIOSYSTEMS
Leica Biosystems is a global leader in workflow solutions bringing
histopathology laboratories and researchers the highest quality, most
comprehensive product range in anatomical pathology. With complete
histology systems featuring innovative automation, NovocastraTM
reagents and Surgipath® consumables, Leica Biosystems offers the ideal
product for each histology step and high-productivity workflow solutions
for the entire laboratory.
Leica Biosystems – an international company with a strong network of
worldwide customer services:
North America Sales and Customer Support
North America 800 248 0123
Asia/Pacific Sales and Customer Support
Australia 1800 625 286
China +85 2 2564 6699
Japan +81 3 5421 2804
South Korea +82 2 514 65 43
New Zealand 0800 400 589
Singapore +65 6779 7823
Europe Sales and Customer Support
For detailed contact information about European sales offices or distributors please
visit our website.
95.10599 Rev B - Order no. 1195.10599 · 09/2012 · Copyright © by Leica Biosystems
Melbourne Pty Ltd, Melbourne, Australia, 2012. Subject to modifications. LEICA and the
Leica Logo are registered trademarks of Leica Microsystems IR GmbH.
Leica Biosystems brings
together products, quality and
support. Offering a complete
solution that helps you advance
workflows, enhance diagnostic clarity and
deliver what really matters – better patient care.
www.LeicaBiosystems.com
