Release Notes Chromeleon 7.2.6 7.2.6m User Manual

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ReleaseNotes

Chromeleon7

ChromatographyDataSystem

SoftwareVersion7.2.6•August2017

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Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1

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ReleaseNotesPage2

Copyright

ForResearchUseOnly.Notforuseindiagnosticprocedures.Copyright©2009‐2017ThermoFisherScientific

Inc.Allrightsreserved.

Trademarks

ACQUITY,AllianceandWatersareregisteredtrademarksofWatersCorporation.ACQUITY,AllianceandWaters

areregisteredtrademarksofWatersCorporation.AgilentisaregisteredtrademarkofAgilentTechnologies.

Microsoft,Windows8.1Pro,.NETFrameworkandSQLServerareregisteredtrademarksofMicrosoft

Corporation.PerkinElmerandClarusareregisteredtrademarksofPerkinElmerInc.Shimadzuisatrademarkof

ShimadzuCorporation.AirServer‐xr,TD100‐xrUNITY‐xrandKori‐xraretrademarksofMarkesInternationalLtd.

WibuKeyisownedbyWibuSystems.

AllothertrademarksarepropertyofThermoFisherScientificInc.anditssubsidiaries.

ThermoFisherScientificInc.providesthisdocumenttoitscustomerswithaproductpurchasetouseinthe

productoperation.Thedocumentiscopyrightprotected;anyreproductionofthewholeoranypartofthis

documentisstrictlyprohibited,exceptwiththewrittenauthorizationofThermoFisherScientificInc.

Thisdocumentisprovided“asis”.Thecontentsofthisdocumentaresubjecttobeingchanged,withoutnotice,

infuturerevisions.

ThermoFisherScientificInc.makesnorepresentationsthatthisdocumentiscomplete,accurate,orerror‐free.

ThermoFisherScientificInc.assumesnoresponsibilityandwillnotbeliableforanyerrors,omissions,damage,

orlossthatmightresultfromanyuseofthisdocument,eveniftheinformationinthedocumentisfollowed

properly.

ThisdocumentisnotpartofanysalescontractbetweenThermoFisherScientificInc.andapurchaser.This

documentshallinnowaygovernormodifyanyTermsandConditionsofSale.TheTermsandConditionsofSale

shallgovernallconflictinginformationbetweenthetwodocuments.

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Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1

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ReleaseNotesPage3

TableofContents

1Introduction.............................................................................................................................5

2OtherDocumentation.............................................................................................................6

3What’sNewinChromeleon7.2.6...........................................................................................7

3.1NewandUpdatedThermoScientificInstrumentDrivers................................................7

3.1.1NewISQECMassSpectrometerDriver[SWFR‐1214]...............................................7

3.1.2UpdatedVanquishHorizonBinaryPump(VH‐A10)Driver[SWFR‐2700]...................7

3.1.3UpdatedTRACE1110FPD[SWFR‐2474]....................................................................7

3.1.4UpdatedTRACE1300GCDriver[SWFR‐1518,SWFR‐1512,SWFR‐1558]..................7

3.1.5FractionCollectionWizardSupportForMultipleChannels[SWFR‐1192].................7

3.2NewandUpdatedThirdPartyInstrumentDrivers...........................................................7

3.2.1NewMarkesThermalDesorberDriver[SWFR‐1234]................................................8

3.3IQ/OQ/PQ..........................................................................................................................8

3.3.1LinkinganIQTemplatetoMultipleSequences[SWFR‐2567]...................................8

3.3.2HPLCIQfornewISCECLC/ICMS[SWFR‐2649]..........................................................8

3.4ChromeleonXPS................................................................................................................8

3.4.1ChromeleonXPSOptionalUserInterface[SWFR‐2207]............................................8

3.4.2ChromeleonXPSUserPrivileges[SWFR‐2430]...........................................................9

3.5EmailNotificationEnhancements.....................................................................................9

3.5.1SendE‐MailonSequenceCompletionorAbort[SWFR‐2281]..................................9

3.5.2NotificationofLicenseGracePeriod[SWFR‐2841,SWFR‐1090]................................9

3.5.3NotificationofPendingExpirationforTemporaryLicenses[SWFR‐2899].................10

3.6ProcessingMethodEnhancements..................................................................................10

3.6.1IdentifyPeaksBasedonMassSpectrum[SWFR‐967]...............................................10

3.6.2SupportforTargetMassScreening[SWFR‐1483]......................................................10

3.6.3BioPharmaWorkbookImportwithExactiveAcquisitionList[SWFR‐2093]..............10

3.6.4PerformISTDquantitationBasedonRatio(Resp)vsRatio(Amt)[SWFR‐2374].......10

3.7OtherChromatographyStudioEnhancements................................................................10

3.7.1LabelingaChromatogramPeakwiththeDetectedMass[SWFR‐1482]....................10

3.7.2FixedAxisScalingForMSComponentsPlot[SWFR‐2655].........................................10

3.7.3RelativeStandardErrorasaReportVariable[SWFR‐2467].......................................10

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1

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ReleaseNotesPage4

4ResolvedIssues........................................................................................................................11

5LimitationsandKnownIssues.................................................................................................15

5.1LimitationswithThermoScientificInstruments...............................................................15

5.2CompatibilityofChromeleon7.2.6andSIIforXcalibur...................................................16

5.3MassSpectrometersandWindows10.............................................................................17

5.4UpgradingaWindows10PCFromChromeleon7.2SR5toChromeleon7.2.6...............17

5.5CompatibilitywithFoundation3.1...................................................................................17

5.6LimitationswiththeWatersDriverPack..........................................................................17

5.7LimitationswithAgilentICF..............................................................................................19

5.8LimitationswithOtherThirdPartyInstruments...............................................................21

5.9OtherLimitations..............................................................................................................22

5.10ObsoleteDrivers...............................................................................................................24

5.11DefectsUnderInvestigation.............................................................................................24

5.11.1EmptyInjectTimeandGUIDFieldsintheInjectionRecord[CM7‐22738]............25

5.11.2InstrumentAuditTrailsArenotProperlySaved/WrittenonthelocalDataVault

[CM7‐23051].........................................................................................................................25

5.12FunctionalDifferencesbetweenChromeleon7.2andChromeleon6.8..........................25

6Backward/ForwardCompatibilityIssues.................................................................................26

6.1ThermoScientificVanquishChargedAerosolDetector[CM6‐23499].............................26

6.2ThermoScientificVanquishAutosampler[CM6‐23405]..................................................26

6.3ThermoScientificTriPlusRSH...........................................................................................26

6.4ThermoScientificTriPlus300HS......................................................................................26

6.5ThermoScientificTriPlusLS‐100.......................................................................................26

6.6ThermoScientificTSQQuantiva.......................................................................................26

6.7ThermoScientificTSQQuantivaandEndura....................................................................26

6.8TSQQuantivaandEnduraInstrumentMethod[CM7‐18759]..........................................26

6.9SignedSequences[CM7‐16374].......................................................................................27

7Appendix..................................................................................................................................28

7.1ReleaseNotes...................................................................................................................28

7.2OnlineHelp.......................................................................................................................28

7.3ContributedContent.........................................................................................................28

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Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1

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ReleaseNotesPage5

1 Introduction

TheThermoScientific™Chromeleon™7ChromatographyDataSystem(CDS)isanew‐generation

chromatographydatasystemthatprovidesthefastestpathfromsamplestoresults.Buildingupon

market‐leadinginnovationsofpriorChromeleonsoftwarereleases–suchasdynamicinteractivedata

displays,anintegrateddatabaseforrapiddataretrieval,andspreadsheet‐basedreporting–

Chromeleon7featuresamodernuserinterface,comprehensivenewtoolsforpeakdetection,andan

innovativeworkflowmanagementframework,allofwhichspeeduplearning,simplifyoperation,and

deliverresultswithgreaterefficiencythananyotherchromatographydatasystem.

Thisnewversion,Chromeleon7.2.6CDS,providesupdatedandnewinstrumentcontrolfor

instrumentsfromThermoFisherScientificandothervendors.Improvementsandenhancements

havebeenmadeinanumberofareasrelatedtodataprocessingandvisualization.Inaddition,this

releaseintroducesChromeleonXPS‐ahighlystreamlinedandsimplifiedoptionaluserinterfacefor

Chromeleontosupportwalkupautomationlabenvironments.Pleaseseebelowformoredetailson

theseandotherenhancementspresentinthisrelease.

Thesoftwareisdevelopedusingmodernsoftwaredevelopmenttoolsandtechnologiesthatimprove

performance,sustainabilityandextendibility.

BackwardcompatibilitywithChromeleon6ismaintainedtothegreatestpracticableextent,to

provideaneasymigrationpath.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage6

2 OtherDocumentation

Chromeleonisprovidedwithmanyotherdocumentsthatwillhelpyoutolearnmoreaboutthe

software.TheirscopeisdescribedintheDocumentOverview,whichisdeliveredinprintedformwith

theChromeleoninstallationmedia,butalsoavailableinelectronicformontheinstallationdiskinthe

Documentsfolder.

PleaserefertotheInstallationGuideforinformationregarding:

 SystemRequirements

 SupportedOperatingSystemsandDatabases

 RequiredThird‐PartySoftware

 CompatibilitywithPreviousVersions

 InstallingandconfiguringtheChromeleonsoftware

Tip:TheGlossarydescribesChromeleon‐specifictermsandcommonabbreviationsused

throughoutthedocumentation.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage7

3 What’sNewinChromeleon7.2.6

Chromeleon7.2.6implementsanumberofnewfeatures,includingsupportfornewhardware,

ChromeleonXPS(anewsimplifieduserinterfaceforopenaccesswalkupautomationlabs)and

improvementstodatareviewandprocessingofMSdata.Thisdocumentwillonlygiveashort

overviewofallfeatureswithoutgoingintomuchdetail.Formoredetails,refertotheOnlineHelp.

3.1 NewandUpdatedThermoScientificInstrumentDrivers

ThischapterlistsnewandupdatedThermoScientific™driversaddedtoChromeleon7.2.6.For

detailsonsupportedoptions,requiredlicenses,installation,andcontrol,refertotheOnlineHelpor

theListofSupportedInstrumentsdocumentfoundontheChromeleon7.2.6DVD.

3.1.1 NewISQECMassSpectrometerDriver[SWFR‐1214]

ThisreleaseincludessupportforthenewThermoScientificISQEC,whichisasinglequadrupolemass

spectrometerforHPCandIC.

3.1.2 UpdatedVanquishHorizonBinaryPump(VH‐A10)Driver[SWFR‐2700]

TheVanquishHorizonBinaryPumpdriverandePanelhavebeenenhancedtoincludetheabilityto

performapumpleaktest.

3.1.3 UpdatedTRACE1110FPD[SWFR‐2474]

TheTRACE1110GCdriverhasbeenenhancedtosupportanupdatedFlamePhotometricDetector

withahighertemperaturerange.

3.1.4 UpdatedTRACE1300GCDriver[SWFR‐1518,SWFR‐1512,SWFR‐1558]

TheTRACE1300GCdriverhasbeenenhancedasfollows:

 AnoptionhasbeenaddedtotheconfigurationdialogtoallowtheGChardwarekeyboardto

remainunlockedwhilestillconnectedtoChromeleon.

 Anoptionhasbeenaddedtothemethodeditortorestoredefaultvaluesforallofthe

methodsettingsonapageorforanentiremethod.

 Itisnowpossibletostartdetectoracquisitionatatimeotherthan0.0min.

3.1.5 FractionCollectionWizardSupportForMultipleChannels[SWFR‐1192]

Theexistingfractioncollectionwizardhasbeenenhancedtoincludethesetupofmultiplechannels

andallfractioncollectionparameters.





3.2 NewandUpdatedThirdPartyInstrumentDrivers

ThischapterlistsnewandupdateddriversaddedtoChromeleon7.2.6.Fordetailsonsupported

options,requiredlicenses,installation,andcontrol,refertotheOnlineHelpandtheListofSupported

InstrumentsdocumentfoundontheChromeleon7.2.6DVD.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage8

3.2.1 NewMarkesThermalDesorberDriver[SWFR‐1234]

ThisreleaseincludesanewinstrumentdrivertocontrolthefollowingmodulesfromtheMarkes

ThermalDesorberproductline:

 TD‐100‐xrStandard(includingtheTubeISaccessory)

 TD‐100‐xrAdvanced(includingtheTubeISaccessory)

 Unity‐xr(includingtheAirServeraccessory)

 Kori‐xr





3.3 IQ/OQ/PQ

3.3.1 LinkinganIQTemplatetoMultipleSequences[SWFR‐2567]

Itisnowpossibletocreateandstoreasingleinstanceofthequalificationreporttemplatesina

folderoutsideofasequenceandlinkmultiplequalificationsequencestothattemplate.

3.3.2 HPLCIQfornewISCECLC/ICMS[SWFR‐2649]

TheHPLCIQtemplateshavebeenupdatedtosupportforthenewVanquishISQECMSmodule.





3.4 ChromeleonXPS

3.4.1 ChromeleonXPSOptionalUserInterface[SWFR‐2207]

ChromeleonXPSisahighlysimplifieduserinterfaceforChromeleonthatprovideswalk‐up,multi‐

useraccessforroutineanalysisbynon‐chromatographers.

Featuresinclude:

 Clean,streamlined“walk‐up”interface

 UtilizesthefullpowerofChromeleon’susermanagement,instrumentcontrol,data

processingandreporting

 ProvidesaccesstoallinstrumentsinanEnterpriseenvironment

 SupportsIC,LC,GC,LCMS,GCMSandICMSanalysis

 eMailnotificationofruncompletionandanalysisresults

 Managementconsolewithadvancedcustomizationoptions



Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage9



Important:ChromeleonXPSisalicensedoptionforChromeleon,Pleasecontactyourlocal

ThermoFisherScientificrepresentativefordetailsonenablingthisfunctionality.



3.4.2 ChromeleonXPSUserPrivileges[SWFR‐2430]

TheUserManagementpermissionssethavebeenenhancedtocontroltheabilitytouseandmanage

theChromeleonXPSsoftware.

Thenewpermissionsinclude:

 ManageUserInterface

AllowsalabmanagertocustomizetheChromeleonXPSuserinterface,specifyavailable

eWorkflowsanddefinedefaultbehaviors

 UseClientUserInterface

RequiredinorderforausertobeabletologintoChromeleonXPS







3.5 EmailNotificationEnhancements

3.5.1 SendE‐MailonSequenceCompletionorAbort[SWFR‐2281]

Withthisrelease,itisnowpossibletohaveane‐mailnotificationsenttooneormoreuserswhena

sequencecompletesorisaborted.Thee‐mailincludesbasicinformationsuchassequencename,

instrument,andtime/dateaswellasalinktothesequenceitself.

3.5.2 NotificationofLicenseGracePeriod[SWFR‐2841,SWFR‐1090]

Withthisrelease,whenthesoftwarelicensedongleisinaccessible(e.g.duetoanetworkproblem)a

notificationisdisplayedinthemessagebaroftheChromeleonConsole.

Inaddition,itispossibletoenableanemailnotificationbesenttoalertappropriatepeople.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage10

3.5.3 NotificationofPendingExpirationforTemporaryLicenses[SWFR‐2899]

Withthisrelease,itispossibletoenableanemailnotificationwhenatemporarysoftwarelicenseis

abouttoexpire.



3.6 ProcessingMethodEnhancements

3.6.1 IdentifyPeaksBasedonMassSpectrum[SWFR‐967]

ItisnowpossibletospecifyanMSspectrumandmatchcriteriaintheprocessingmethodwhichcan

beusedtoidentifyorconfirmtheidentificationofcomponents.

3.6.2 SupportforTargetMassScreening[SWFR‐1483]

Withthisrelease,itisnowpossibletospecifytargetscreeningmassesonaper‐injectionbasis.The

specificationalsoincludessupportforpositiveandnegativeadducts.Massspectrumplotsmaybe

taggedwiththetargetmass(ifdetected)andreportvariablescanbeusedtodisplayandtestifthe

targetmasswasdetected.

3.6.3 BioPharmaWorkbookImportwithExactiveAcquisitionList[SWFR‐2093]

TheCompoundImportfeatureoftheprocessingmethodhasbeenenhancedtosupportBiopharma

Finderworkbookexportfiles.

3.6.4 PerformISTDquantitationBasedonRatio(Resp)vsRatio(Amt)[SWFR‐

2374]

Withthisrelease,whenusingvariableinternalstandardamountsthedefaultcalibrationoptionfor

newsequencesisnowtocomputetheresponsefactorbasedonResponseRatiovs.AmountRatio.



3.7 OtherChromatographyStudioEnhancements

3.7.1 LabelingaChromatogramPeakwiththeDetectedMass[SWFR‐1482]

Whenperformingtargetedmassscreening,itisnowpossibletolabelachromatographicpeakwith

thedetectedmass.



3.7.2 FixedAxisScalingForMSComponentsPlot[SWFR‐2655]

TheMSComponentsreportobjecthasbeenenhancedtoallowspecificationofafixedsignalscale.

Thisresponserangemaybedirectlysuppliedbytheuserormaybeautomaticallyextractedfroma

referenceinjection.

3.7.3 RelativeStandardErrorasaReportVariable[SWFR‐2467]

RelativeStandardError(%RSE)isnowbeingrequiredinanumberofEPAstandardmethods.This

releaseincludes%RSEasastandardreportvariable.



Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage11

4 ResolvedIssues

ThischapterdescribestheissuesthathavebeenresolvedwiththereleaseofChromeleon7.2.6.

Manytrivialandminorissueshavebeenresolved,butarenotmentionedhere.Ifyourequire

informationaboutthestatusofanissueobservedinaChromeleon7release,butwhichisnotlisted

here,pleasecontactyourlocalThermoFisherScientificrepresentativeformoreinformation.

ThenumbersinthefirstcolumnofthetablebelowrefertotheThermoFisherScientifictrackingIDs.

IDDescription

CM7‐23867A2D:OccasionallywhenanA2DwasunpluggedfromanIPC,theAuditTrailwould

containrepeated"{A2D}Dataoutofsequence"errorsuntiltheA2Dwas

reconnected.TheAuditTrailnowshowstwonewmessages:"{A2D}A2DUSB

communicationerror"and"{A2D}Driverhasdisconnected",eachofwhichis

reportedjustonce.

CM7‐23552AS/AI1310Sampler:Occasionally,anewsamplerfromthefactorywasunableto

connecttoChromeleon.

CM7‐22328Calibration:InjectionsusedforfixedcalibrationwithMSwerenotwrittentothe

chromatogramcachesothatresultshadtoberecalculatedwheneveraccessed

causingpoorperformance.

CM7‐23893Calibration:Responseleveltoleranceswerealwayscomputedusingtheamounts

specifiedintheprocessingmethod,withouttakingintoaccountnormalizationfor

sampleweight,dilutionfactor,injectvolumeandamountratios.

CM7‐23925Calibration:Whencalculatingconfidencelimits,appliedinjectionweightordilution

factorcorrectionswerenottakenintoaccountmeaningthat

peak.confLowerLimit("computed")wasequivalentto

peak.confLowerLimit(peak.amount).Thesameappliedalsofortheupperlimits.

CM7‐8269ChromatogramPlot:IfaChromeleon6sequencedisplayingRetentionTimeand

ComponentNameasPeakLabelsontheChromatogramplotwasopenedin

Chromeleon7thePeakLabelswouldnotbeshowncorrectly.

CM7‐23995Console:Inrarecases,thedatacategorynavigationtreeiconswouldnotdisplay

properly.

CM7‐23771Copy/Paste:WhentheMSComponentsplotwassmartlinked,expandingasingleplot

thencopy‐and‐pastingtheplotresultedinpastingofthesmartlinkedplotratherthan

theexpandedplot.

CM7‐23852ElectronicReport:Thereportvariables'gen.reportTime'and'gen.reportOperator'did

notdisplaycurrentvaluewhenusedinareportvariableinthegrid,sincetheywere

notupdatedinreporttablesandplotsaftereachaction.Thereportvariablesarenow

properlyupdated.

CM7‐23833ElectronicSignatures:Whensigningasequencethatwascurrentlyintheprocessof

beinguploadedtotheEnterpriseDataVault,thedataaudittraildidnotcontain

entriesrecordingtheelectronicsignatureevent.Awarningisnowdisplayedandthe

userisnolongerpermittedtosignsequencesthatarebeinguploaded.

CM7‐23419eWorkflows:AddingadditionalsamplestoaSequencethatwascreatedfroman

eWorkflowwouldalwaysplacethenewsamplesaftertheFooterblock.Chromeleon

nowprovidesanoptionto"preserve"the[Header][Sample][Footer]layoutwhen

additionalsamplesareaddedbyre‐runningtheeWorkflow.

CM7‐6793eWorkflows:IntheeWorkflowseditor,anoptionhasbeenaddedtospecifyifthe

bracketblockshouldalsobeincludedbeforethefooterblock

CM7‐23401eWorkflows:Whenusingan eWorkflowtoappendinjectionstoasequencethatwas

createdbyadifferenteWorkflow,ifthesequencecontainedinjectioncustom

variables,anerrorstating"Differentfielddefinitionforanexistinginjectioncustom

variable"wasgenerated.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage12

IDDescription

CM7‐23950eWorkflows:XVaultsequencewasnotusedwhenappendinginjectionsusing

eWorkflows,toarunningsequence.

CM7‐23250ExtractedIonChromatograms:Insomeinstances,thestartorendtimesofa

componentextractedionchromatogramforaspecificinjectionwouldvary

dependingonwhichotherinjectioninthesequencewasselected.

CM7‐24036ExtractedIonChromatograms:WhenextractinganionchromatogramfromMSdata,

thedataextractedwascorrect,butthechannelnameindicatedanincorrect

extractionwindowbydefault.

CM7‐23895GCMSEnvironmentalExtensionPack:TheAdHocBFBTuneReportincorrectly

evaluatedm/z173criterion.

CM7‐23963HelpandManuals:ShimadzuLC‐20AandLC‐30A‐ Theonlinehelpdidnotdescribe

fullythenecessarystepsforusingInjectSynchronisation.

CM7‐23732Import/Export:ExportofsequencedatatoMicrosoftExceloccasionallycaused

ChromeleontogeneratevariouserrorsduetoexceedingGDIlimits.

CM7‐24083Import/Export:IfaSequenceimportedfromChromeleon6containedalargenumber

ofhistoryentries,attemptstocopytheSequence,orSendtoCMBXcouldresultinan

"Exceptionoftype'System.OutOfMemoryException'wasthrown"errormessage.

CM7‐24021Import/Export:Occasionally,afterimportingaChromeleon6.8CMBfile,Chromeleon

wouldreportanerror"Chromeleonisnolongerworkingandneedstobeclosed.

CM7‐21418Import/Export:ProducingPDFandExcelexportssimultaneouslyresultedinincorrect

pagenumberingintheexportedfiles.

CM7‐23600Installation:WhenupgradinganInstrumentPCfromChromeleon7.2SR4to7.2SR5,

ifthereweresequencesstillintheinstrumentqueuethathadnotbeenuploadedto

theremoteserver,an˜UploadFailure"errorwouldbedisplayedandreportedinthe

DataError.logandTxpStatistic.loglogfiles.

CM7‐24055InteractiveResults:WhendisplayingInteractiveResultsintheStudioforunknowns,if

calibration‐relatedsettings(e.g.dilutionfactor)arechangedintheconsolefora

calibrationstandard,theInteractiveResultstablewasnotautomaticallyrefreshedto

displaytheupdatedamounts.

CM7‐23567Non‐TargetedMSDataProcessing:Modifyingonlythetablefilterparametersdidnot

triggerasaveoption.

CM7‐23723Non‐TargetedMSDataProcessing:TheRelativeReferenceInjectionnumbersetting

nowstartsat1insteadof0.

CM7‐23883OQ/PQ:IftheStationPQwasrunmorethanoncewithinthesameclientsession,the

followingactionswereskippedafterthefirstrun:"ReadyCheckforQueue","Check

InstrumentStatus","CheckInstrumentState","StartQueue","StopQueue",and

"EditSequenceinQueue."

CM7‐23364OQ/PQ:IfanactionwassettobenotexecutedduringthePQ,anyactionsdepending

onthiswouldalsonotbeexecutedduringthePQ.

CM7‐23769Printing:Whenperforminganadhocprintoftheprocessingmethod,thesettingsfor

theConcentrationLevelToleranceswerenotincludedintheprintout.

CM7‐23843ProcessingMethod:Undercertaincircumstances,itwasnotpossibletodisplaythe

processingmethod(oropenasequencewiththeprocessingmethoddisplayed).This

occurredwhenthenumberoffrozencolumns=numberofcolumnsandthesizeof

theStudiowindowwastoosmalltoshowallcolumnsofthetable.

CM7‐23740Query:Whensearchingforinjectionsbydateusingtheoperator"IsNotDuring

Previous",thequeryresultwouldalsoreturninjectionscreated/modifiedduringthe

currentday.

CM7‐23009ReportDesigner:Whenclosingprintpreview,GDIobjectsforplotobjectswerenot

released,resultinginamemoryleak.

CM7‐23230ReportVariables:Anincorrectvaluewasreportedwhenextractingthe2ndand

higher“ByIntensity”massesfromalibraryspectrum.

CM7‐23724ReportVariables:Insomeinstances,theNon‐TargetedMSDataProcessingResult

Statusvariablewouldnotupdateinreal‐time,resultinginincorrectin‐spec/not‐in‐

specresultsbeingdisplayedinthereporttemplate.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage13

IDDescription

CM7‐23616ReportVariables:Thepeptidecategoryreportvariablesdisplayed"n.a."whenusedin

asummarytable.

CM7‐23306ReportVariables:Whenspecifyingacustompercentheightforthecalculationof

peakwidth,onlyintegervalueswereaccepted.Thishasbeenupdatedtosupport

decimalvalues.

CM7‐23749ReportVariables:Whenusingdifferentinjectionvolumesinacalibrationcurve,the

amountdeviationreportvariablewascalculatedincorrectly.

CM7‐23592Sequence:Appendinganewinjectiontoanexistingsequenceorinsertinganew

injectioninanexistingsequencecausedanerrormessagestating'Theprivilege"Copy

Injection"ismissing.'Theseoperationsnowrequireonlytheprivilege"AddNew

Injection".

CM7‐17326Sequence:Ifavaluewasenteredinatablecolumnthathadagreaternumberof

decimalplacesthantheprecisionspecifiedforthecolumn,anerrorthattherewere

toomanydigitswasdisplayed.Theenteredvalueisnowacceptedbutroundedto

matchthecolumn'sprecision.

CM7‐23911Sequence:IftheESCkeywaspressedveryquicklyafterstatingtheNewSequence

Wizard,itwaspossibleforaNullReferenceExceptionerrortooccur.

CM7‐23072Sequence:ImportingaChromeleon6.8reportintoChromeleon7thatcontainsa

largenumberofimages(plots,etc.),thenattemptingtosubmitthesequencein

Chromeleon7wouldcausethesoftwaretocrash.

CM7‐23913Sequence:Itwaspossibletomakeandsavechangestotheassociateditemsand

someotherfieldsinanunconvertedimportedsequence.

CM7‐24141Sequence:Useofdefaultexporttemplatedefinedpersequencewhenrunninga

multi‐sequencequeueresultedinonlytheuseofthedefaulttemplateforthefirst

sequencefortheentirequeue.

CM7‐24140Sequence:Useofdefaultreporttemplatedefinedpersequencewhenrunninga

multi‐sequencequeueresultedinonlytheuseofthedefaulttemplateforthefirst

sequencefortheentirequeue.

CM7‐18753SystemStatusReport:IftheSSRencounteredafilewhichhadtheRead‐onlyflagset,

itwouldfailwithanerror"Deletingtemporaryfiles:Unabletoremovethetemporary

files:Accesstopath<filepath>denied".

CM7‐18754SystemStatusReport:IftheSSRfailedtodeleteatemporaryfile,itwasnotincluded

inthereport.

CM7‐19607SystemStatusReport:IftheSSRwasnotabletoaccesstheInstrumentAuditTrails,

theInstrumentAuditTrailssectionoftheSummaryReportwouldreportthis,but

withanunclearmessage.

CM6‐23654TRACE1110GC:Althoughtheinstrumentfrontpanelsupportedvaluesfrom0to100

ml/minfortheinletflowrate,themaximumvalueallowedbytheinstrumentmethod

editorwas70foraPackedinletwithEPC,and25foraPTVinletwithEPC.

CM7‐20118TRACE1110GC:OnthePTVpageofthemethodeditor,theSplitRatioparameterwas

notcheckedtoensureavalidvaluewasentered.

CM7‐14454TRACE1300GC:Itwasnotpossibletousecustominjectionvariablesorcustom

sequencevariablesaspartoftheinstrumentmethodscript.

CM7‐23317TRACE1300GC:OntheAuxColumnsePanel,theColumnParametersforAux

Columnswassetincorrectlywhenmorethan2Inletswereconfigured.

CM6‐24124TRACE1300GC:OntheInletmethodpage,theHeSaverDelayTimewaslimitedtoa

maximumof0.5minutes,eventhoughthehardwaresupportedatimeupto2.0

minutes.

CM6‐23871TRACEGCUltra:Ifaninstrumentmethodwithanisothermalovensegmentatthe

beginningwasusedforasampletypeblank,theisothermalsectionwasignored.

CM6‐24109TriPlus300HS:Althoughthehardwaresupportsanoptionalbarcodereader,there

wasnowaytoreportthebarcodevaluethatwasread.

CM6‐24169TriPlusRSHandTriPlus100LS:AfterEditingCustomCycleParameters,itwasnot

possibletosavetheeditedmethoduntilachangewasmadeelsewhereinthe

method.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage14

IDDescription

CM7‐23177TriPlusRSHandTriPlus100LS:AfteropeningandclosingtheVirtualTerminal,itwas

notpossibletorestarttheChromeleonConsole.

CM6‐24212TriPlusRSHandTriPlus100LS:Ifasamplefishedacquiringbeforethesampler

finisheditsinjectioncycle(e.g.duetopost‐injectionwashes),thesequencewould

interruptwithfollowingerrorintheaudittrail:"Timeoutwhilewaitingforthe

instrumenttofinish,thecurrentinjectionwillbeaborted."

CM7‐23711TriPlusRSHandTriPlus100LS:Whenrunningsequencesonaninstrumentusing

version2.4ofthefirmware,occasionallythesequenceswouldabortwithanerror

messagestating"Thereisaproblemwithaccessingtheinstrument."

CM7‐21564TriPlusRSH:AlthoughitwaspossibletoconditiontheSPMEfiberaspartofan

instrumentmethod,itwasnotpossibletodosomanually.

CM6‐23479TriPlusRSH:WhenoperatinginSPMEmode,theTriPlusRSHwouldschedulesamples

soastooverlapovenprograms,butdidnotoptimizebasedonthevariousSPME

incubationsteps.

CM7‐24009TriPlusRSH:ItwasnotpossibletomanuallyconditiontheSPMEArrowtool

CM6‐24161TriPlusRSH:Itwasnotpossibletostartasequenceifoneoftheagitatorpositions

wasconfiguredasaReservedPositionusingadifferentvialtype.

CM6‐24168TriPlusRSH:WithaninstrumentconfigurationthatincludedbothaTriPlusRSHanda

ManualInjectmodule,occasionallythestateforaninjectionwouldnevertransition

to'Finished',effectivelyhangingthesequence.Theissuewasonlyseenforinjection

rowsthatusedtheManualInjectoption.

CM6‐24151TSPUV6000PDA,SurveyorPDA,SurveyorPlusPDAandAccelaPDA:Occasionally

duringacquisition,an"AccessViolation"errorwasgenerated,haltingthesequence.

CM7‐19507UltiMateAFC‐3000,WPS‐3000(FCvariants):Whencreatinganinstrumentmethod

withfractioncollection,theoptionforfractionpoolingwasalwaysdisabled.

CM7‐23624URG‐9000:WheninstalledontheFrenchversionofWindows7,aformaterrorwould

bedisplayedinsteadofthefloatingpointcalibrationvalues.

CM6‐23927VanquishAutosampler:WhenusingaWaters48Racktype,itwasnotpossibleto

addressthelasttwocolumnsoftherack(7/8).

CM7‐23178WatersAcquity:IfanAcquity instrumenthadpreviouslybeenconfiguredandthen

deleted,itwasnotpossibletoseethemoduleswhenattemptingtoconfigurean

Acquityinstrumentatalaterpoint.Whiletheproblemhasbeensolvedin

Chromeleon7.2SR5MUa,usersofversionsolderthanthisshouldcontactThermo

FisherScientificforfurtherinformation.











Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage15

5 LimitationsandKnownIssues

Thefollowingsectionslistknownissuesandlimitations.Thenumbersinthefirstcolumnofthetable

belowrefertotheThermoFisherScientifictrackingIDs.

5.1 LimitationswithThermoScientificInstruments

ID Description

CM7‐16851UltiMate3000MWD‐3000andDAD‐3000:IntheInstrumentMethodEditorforthese

devices,thescriptpageoffersoneadditionaloptionforthedatacollectionrate(20Hz)

thatisnotpresentintheInstrumentMethodWizard.Thisadditionaloptionisavalid

valueforthisparameter.

Althoughitispossibletomanuallytypeinavalueforthedatacollectionratethatisnot

inthelist,thesevalueswillberejectedbytheReadyCheckwhenasequenceis

submitted.

CM7‐17783UltiMate3000WPS‐3000FC:WhenusingtheWPS‐FC,theneedlewillnotautomatically

beflushedpriortocollectingthefirstfraction.Toworkaroundthislimitation,addthe

followinglinestotheinstrumentmethodcommandscript:

Sampler.EndFraction

Sampler.Collect

Delay10

Sampler.Drain

CM7‐21342VanquishVariableWavelengthDetector:Foracquiringdataonasinglechannelonly

usingtheVanquishVWDitisnecessarytousechannelUV_VIS_1.

CM6‐21321AccelaOpenAutosampler:Whenusingthisautosampler,adot(‘.’)mustbeusedas

decimalseparator.

CM7‐18098AccelaOpenAutosampler:Sequencescannotberunwhenthesamplerdoesnot

includetheDLWoption.Thisconfigurationisnotsupportedandrequiresacustom

script.

CM6‐22760TRACE1300GC:TheautozerofunctiondoesnotworkcorrectlyfortheFID,NPD,ECD

andFPDdetectortypes.

CM6‐23614TriPlusRSH:WhenusingtheTriPlusRSHinconstantdoubleproheadspacemode,

startingasequencethatincludesaconstantdoublepromethodwillgeneratea

validationerror.

CM7‐20295TSQ8000andISQSeries:WhenaGC‐MSinstrumentmethodincludesascanevent

containingmultipleSIMions(e.g.“SIM115,152,188”)thendatafrommatchingfilters

collectedatdifferenttimerangeswillnotbecombinedintoasinglefilterinthedatafor

thatinjection.

CM7‐23669TSQ8000Series:Ifyouattempttoabortanacquisitionofmultipletimedacquisitions

whiletheMSisacquiringdata,theMSwillnotcyclebacktoaReadystateandthe

sequencewillnotend.ItisnecessarytostopandrestarttheInstrumentControllerto

regainaccesstotheinstrument.

CM7‐15632TSQQuantivaandEndura:WhenremovingthesourcefromaTSQQuantivaorEndura

inmid‐acquisition,thesequencedoesnotabort.

CM7‐16030TSQQuantivaandEndura:Withtheseinstrumentsthestandbystatereportsthatthe

instrumentison,regardlessoftherealinstrumentstate.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage16

ID Description

CM7‐16154TSQQuantivaandEndura:WhencreatinganInstrumentMethodfortheTSQEnduraor

TSQQuantiva,theMSruntimeisnotthesameastheChromeleonruntime.Theuser

shouldenterthecorrectruntimeontheMSpageoftheWizard.

CM7‐17668TSQQuantivaandEndura:TSQEnduraandTSQQuantivainstrumentsareusually

shippedwithaPC(“Endura/QuantivaPC”)thatincludesallthenecessaryinstrument

datafiles,suchascalibrationfiles,foroperatingtheMSinstrument.Ifyouwantto

controlaninstrumentusingadifferentPC,makesurethatthespecificinstrumentdata

filesresidingontheEnduraorQuantivaPCarebackedupandtransferredtothenew

PC.Fordetailsonperformingthisprocess,pleaseconsultwithyourlocalMSfield

serviceengineer.

CM7‐18129TSQQuantivaandEndura:AfteranupgradeoftheTSQEndura/Quantivainstrument

driver,anerrormayoccurwhenopeningtheChromeleonInstrumentConfiguration.To

resolvetheerror,removetheChromeleonMassSpectrometerdriverfromthe

configurationandthenadditagain.Thiswillupdatetheconfigurationinformationin

ChromeleontomatchtheupdatedTSQEndura/Quantivainstrumentdriverversion.

CM7‐21967TSQQuantivaandEndura:TheTSQEnduraandQuantivamassspectrometermethod

editorissupportedonEnglishoperatingsystemswithEnglish/UnitedStatesregional

settingsonly.

CM7‐17500ExactiveSeries:ExactiveSeriesinstrumentsareusuallyshippedwithaPC(“Exactive

PC”)thatincludesallthenecessaryinstrumentdatafiles,suchascalibrationfiles,for

operatingtheinstrument.IfyouwanttocontrolanExactiveinstrumentusinga

differentPC,makesurethatthespecificinstrumentdatafilesresidingontheExactive

PCarebackedupandtransferredtothenewPC.Fordetailsonperformingthedata

backupontheExactivePC,refertotheThermoExactiveSeries2.5SP1ReleaseNotes,

sectionBackupprovidedontheChromeleoninstallationdiskinthePackages\Thermo

Exactive\Documentationfolder.

CM7‐22490ExactiveSeries:WhensettingthedivertvalveparametersforanExactiveSeriesMS

witha2‐positionvalve,thevalvepositionsarerecordedintheMSrawdataoppositeof

howthedivertvalveparameterswereconfigured.

CM7‐23295ExactiveSeries:DuetodifferencesinhowtheExactive2.8SP1driverwritesthescan

headerinMSdatafilesduringacquisition,non‐targetedpeakdetectionwillnotwork

correctlywhendatageneratedfromboththeExactive2.8SP1driverandolderdrivers

arepresentinthesamesequence.

CM7‐16557MSQPlusandTuneApplication:WhenusingtheMSQPluswithChromeleontheuser

hastowaitfortheChromeleonInstrumentControllertobeinidlemodebefore

openingtheTuneapplication.Withoutwaiting,theMSQPluswillnotbeabletochange

theoperatingmode(On,Off,Standby),oritwillnotbepossibletoruninjections.To

recoverfromthiserrorboththePCandtheMSQPluswouldhavetoberestarted.

CM7‐23138MSQPlus:ItisrecommendedtouseonlytheMSdriverprovidedontheChromeleon

installationmedium.OtherversionsoftheMSQPlusdrivermaynotbecompatiblewith

Chromeleon.Pleaseconsultyourlocalfieldserviceengineerforadditionaldetails.



5.2 CompatibilityofChromeleon7.2.6andSIIforXcalibur

Atcurrenttime,SIIforXcalibur(SII)hasnotbeenvalidatedforusewithChromeleon7.2.6.Assuch

anyinstallationcombiningSIIwithChromeleon7.2.6isnotsupported.AtatimewhenSIIis

compatiblewiththisrelease,documentationoutliningsupportwillbereleasedwhichwillsupersede

thisknownlimitation.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage17

5.3 MassSpectrometersandWindows10

ThermoScientificFoundation3.0SP2isrequiredformassspectrometersupportunderChromeleon.

AsFoundation3.0SP2isnotcompatiblewithWindows10,nomassspectrometersotherthanthe

ISQECaresupportedunderWindows10atthispointintime.

5.4 UpgradingaWindows10PCFromChromeleon7.2SR5to

Chromeleon7.2.6

WhenChromeleon7.2SR5isinstalledonaWindows10PC,upgradingthatPCtoChromeleon7.2.6

willappeartocompletesuccessfully,withnoIQerrorsorwarnings.However,attemptingtoexporta

sequencetoPDFwillfailwithanerrorstating“Printernotactivated,errorcode–30”.

Toresolvethisproblem,reruntheChromeleon7.2.6setup,selecting‘Repair’ontheopeningscreen

ofthesetupprogram.

5.5 CompatibilitywithFoundation3.1

ChromeleonisonlycompatiblewithThermoFoundation3.0SP2.Usersmayencountersituations

wherePCsprovidedwithmassspectrometerscomepre‐installedwithFoundation3.1ornewer.In

theseinstances,thefactoryproceduretouninstallanyMSinstrumentcontrolcomponentsoftware

mustfirstbefollowedbeforereinstallingFoundation3.0SP2andthemassspectrometerdriver.

Thisproceduremustonlybecarriedoutbyindividualsthathavecompletedthenecessarysoftware

andhardwaretraining.

5.6 LimitationswiththeWatersDriverPack

ID Description

CM6‐21040WatersAcquity:ShouldaWatersinstrumentdetectanIPaddressconflictduringstart

up,theChromeleonCDSdriverwilllogtheerrormessageintheAuditTrail.Ifthis

messageisignored,itwillbedisplayedagainafter2hours,whichcanresultinarunning

samplebeingaborted.

CM6‐21112Waters2998PDA:Localizationtoanon‐EnglishregionalsettingforthePC(e.g.,

German)doesnotfunctioncorrectlyforthetimedeventstable,e.g.,usingaWaters

2998PDAdetectorandsettingatimedeventintheprogramfile(e.g.,wavelength

changeat5minutes).Theeventisrecorded,butwithouttheeventtime.

CM6‐24158Waters2489PDA:AfterchangingtheInstrumentMethodfromsingletodual‐

wavelengthmode(withoutchangingChannelAwavelength),thedatarateforChannel

Bissetincorrectlyandincompletedatacollectionoccurs.

CM6‐23194AfterremovingtheSampleOrganizerfromtheInstrumentConfiguration,theplate

setupisnotupdatedcorrectly.Manuallyupdatingtheplatesettingsintheplatesetup

configurationdialogavoidsthisissue.Ifthetotallengthoftheinstrumentnameplus

detectornameismorethan32characters,thesequencewillabortshortlyafterinitial

injection.Theaffecteddetectorsare:2489,2998,andAcquityFLR.

CM7‐19830WhenusingtheWatersAcquitydriverinaCitrixenvironment,theAcquityconsoledoes

notupdatecorrectlyandthereforedoesn'tshowcurrentlogfileentries.Thisisduetoa

problemintheAcquityconsole,andcanbemitigatedbyusingtheinstrumentaudittrail

onremoteclients.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage18

ID Description

CM6‐24164WhentheWatersDriverPack4isinstalledinaCitrixenvironment,theWorldWIde

WebPublishingServiceisautomaticallydisabled,sothatafterrestartingthePC,the

Citrixwebapplicationisnolongerreachable.Theserviceshouldberesettoautomatic

start,afterwhichtheapplicationcanbereached

CM7‐22872WhenusingtheWatersAcquitydriver,someChromeleonscreensmaynotappear

properly,suchthattextfromthepreviousscreenisstillvisible.Thishasbeenobserved

withtheSequencePropertiesandtheChromeleonLogonscreen.

CM7‐23504InrarecircumstanceswhentheuserconfiguresandthendeletesanAcquityPDA,the

modulewillstillbeshownintheAcquityConsole.Ifacommandisthenexecuted(e.g.

lampon),themoduledisappearsfromtheconsole,afterwhichtheuserthenneedsto

reconfiguretheinstrumentintheChromeleonInstrumentConfigurationManagerin

ordere.g.toturnoffthelamp.

CM6‐24191InextremelyrarecasestheAcquityPDAserverstopsworking,whichthencausesthe

runningsequencetobeinterrupted.

CM7‐23730WhenusingtheWatersAcquityDriverPack4andtryingeithertocreateanew

instrumentmethod,ortoopentheAcquityconsolefromtheePanelaproblem

sometimesoccurs.Amessageappearsinformingtheuserthatlaunchingtheapplication

hadfailed,andthattheAcquitydriverpackmaynotbeinstalled.Ifthisoccurs,theuser

shouldcontactThermoFisherScientificforfurtheradvice.



Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage19

5.7 LimitationswithAgilentICF

ForageneraloverviewregardingtheAgilentInstrumentControlFramework,pleaserefertothe

documentChromeleonandAgilentICF‐QuickStartGuide‐Chromeleon7.2.pdf,foundinthe

\Documents\folderoftheChromeleon7.2CDSDVD.

ID Description

CM7‐19347AgilentG1312BDAD:WhenusingaG1312BDADincombinationwithanoldJetDirect

card,theusermayexperienceproblemscollectingdataat80Hz.Iftheuserobserves

this,theyshouldgetintouchwiththeirlocalThermoFisherScientificrepresentativefor

adviceonpossiblesolutions.

CM7‐20047AgilentVWDG1314B:WhenusingaG1314BVWD,occasionallythechromatogramis

halftheexpectedlength.

CM7‐20991AgilentICF:OccasionallywhenperforminginjectionswithICFcontrolledinstruments

theinjectionvolumeisincorrectlydisplayed,althoughtheinjectionitselfwas

performedcorrectly.

CM7‐21172AgilentICF:IftheuserhasthemonitorDPIsettingsontheirPCsetatgreaterthan

100%,thensomepartsoftheAgilentLCsystemdeviceePanelarenotvisible.

CM7‐23096AgilentICF:IfaFractionCollectorwithThermostatisinstalled,thechannelmappingis

notcorrect.Thiscanberesolvedbyremovingthe<Channelname="FC:DelaySensor">

nodefromDefaultConfiguration.xmlbeforeaddingthedriver.Afterthis,theusercan

configurethemappingforthetwochannelsmanuallyontheSignals(2D)tabofthe

configurationdialog.

CM7‐19540AgilentICF:TheAgilentGCSystemConfigurationdialogincludesentriestoconfigure

the7697AHeadspace,G1888AHeadspace,7890GC,6890GC,68550GC,and7820GC.

Currently,itisonlypossibletoconfigurethe7697AHeadspacesampler.Attemptingto

configureanyoftheothermoduleswillresultinamessageindicatingthatthemodules

arenotsupported.

CM7‐19863AgilentICF:TheAgilentLCSystemConfigurationdialogincludesentriestoconfigurethe

followingdevices,whicharenotsupportedbytherelease:

AllELSDetectors(Driversarenotincluded,sotheycannotbeconfigured)

Multi‐samplerandDADHDR(Althoughconfigurable,theyhaveseveralknownissues

andarethereforenotsupported)

CM7‐21427,

CM7‐18984

AgilentICFwith1100or1200LCDAD:WhenacquiringdatafromanAgilent1100or

1200LCDAD,thesignaltracemaybeshiftedtothestartoftherun,andtheendtimeis

inconsistent.Nodatapointsarelostwithadatarateof

10Hzandslower(>=0.025min0.5sec)

20Hzandalownumberofspectra(allotherthanALLSpectra)

20Hzandspectrumrange190‐400step2

CM6‐23980Agilent7697A:Whenstartingasequencewhilethe7697AHeadspaceSamplerisinan

‘Error’,‘Running’,or‘NotConnected’state,thereadycheckdoesnotgiveanerror

message.Afterthesequencestarts,thefollowinghappens:

Ifthesamplerisinerrorstate,thesequencestartswithoutgettinginterrupted

Ifthesamplerisrunning,thesequencestopswithaudittrailmessage“Sequence

stoppedbyuser”

Ifthesamplerisnotconnected,thesequenceinterruptswithaudittrailmessages“Lost

connectiontoAgilent7697AHeadspaceSampler",and"Theinstrumentisoffline.Check

powertoallmodules,cablingbetweenmodulesandwhethertheconfiguration

matchesthelistofmodules."

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage20

ID Description

CM6‐23992Agilent7697A:The7697HeadspaceSamplerhastwoversions;111‐and12‐vial

capacityconfigurations.TheChromeleondriveriswrittenandtestedwiththe111vial

capacityversion.Thoughnottested,thedriverisexpectedtoworkwiththe12‐vial

capacitymodule.Theusershouldnotusevialpositionsgreaterthan12inthiscase.The

rackviewalwaysshows111vialpositions.

CM6‐24004Agilent7697A:Usingtheinstrumentfrontpanel,theallowedrangeforTransferLine

Diameteris200‐600microns.However,whensettingthisvalueintheChromeleon

instrumentconfigurationthelimitis250‐530microns.

CM6‐24005Agilent7697A:When7697Aheadspaceinstrumentmethodparametersareincludedin

areport,the“fillpressure”parameterisroundedtothenearestinteger.

CM6‐24007Agilent7697A:Someparametersloggedtotheinstrumentaudittrailareroundedto

nearestinteger.However,allvaluesaredownloadedtotheinstrumentwiththeproper

precision.

CM6‐24008Agilent7697A:Wheneditinganexisting7697AHeadspaceinstrumentmethod,ifthe

valuesforPurgeFlow,PurgeTimeorLeakFlowarechanged,theSavebuttonisnot

enableduntiltheuserchangestabs.

CM6‐24009Agilent7697A:WhenconfiguringanAgilent7697A,thereisanoptionintheuser

interfaceto“UploadConfigfromInstrument”.Thisoptiondoesnotwork.Instead,you

willneedtomanuallyconfiguretheinstrumentsettings.

CM6‐23996,

CM7‐19940,

CM7‐21324

Agilent7697A:The7697HeadspaceAutosamplerhastwooptionsforhandlingmissing

vials:PauseandAbort.AnissuehasbeenobservedwhentheAbortoptionhasbeen

selected.Ineithermode,theautosampleroverlapssamplepreparation,i.e.:sample2

ispreparedwhilesample1isacquiring.Iftheautosamplerfindsthatthesample1vial

ismissing,itwillAbortorPausethesequenceatthepointitdiscoversthevialis

missing.However,iftheautosamplerfindsthatthesample2vialismissing,while

sample1isalreadyacquiring,andtheAbortoptionhasbeenselected,theentire

sequencewillbeaborted,includingtheacquiringsample1.

CM7‐19975,

CM7‐20451

Agilent7697A:TheSoftConfigoption,availableviatheICFforAgilentLCs,isnot

supportedfortheAgilent7697HS.ItshouldnotbeaddedtoanycustomePanelasits

usecancauseissuesbyallowingconfigurationchangestobeappliedtothesampler

duringacquisition.

CM7‐19993Agilent7697A:Ifthe7697Alosesitsconnectiontothenetwork,anaudittrailmessage

isaddedindicatingthisfact.However,theePanelwillstillshowtheunitas‘Ready’.

CM7‐20259Agilent7697A:Althoughthevialpositionmaybeassignedintheinstrumentmethod

script,unlessthisisdoneintheInstrumentSetupStage,thesequencetablewillnotbe

updated.Thiscanresultinmisleadinginformationinreportsandshouldbeavoided.

CM7‐23242Agilent7697A:Runningmultiple7697AHeadspaceautosamplersonasingle247

InstrumentControllercancauseWindows"OutOfMemory"errors,requiringareboot

ofthe247toresolve.ThermoFisherthereforerecommendsthatonlyone7697Ais

connectedtoany247InstrumentController.









Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage21

5.8 LimitationswithOtherThirdPartyInstruments

ID Description

CM7‐17948ShimadzuLC:Unlikemostdrivers,someShimadzuUVdetectorsrequirethatyouselect

theAdvancedfilterintheCommand(F8)windowinordertoaccesstheLampOn/Off

command.

CM7‐24042InstrumentConfigurationManager:The.NET4.7frameworkisinstalledbyWindows

Update.ForWindows7itisarecommendedupdate,butforWindows10itisa

mandatoryupdate.ThisreleaseofChromeleonhasbeenvalidatedagainst.NET4.7.

However,underrarecircumstances,theinstallationof.NET4.7couldleadto

malfunctioningorcrashesoftheinstrumentconfigurationmanagerorconfiguration

plug‐ins.Ifthisoccurs,pleasecontactyourChromeleonsupportdeskforassistancein

correctingtheproblem.

CM6‐23947ShimadzuLC‐10A,LC‐2010:Iftheusercancelsthekeylockstateofthefrontpanelofthe

instrumentandthen,forexample,stopsamanualacquisition,thisislikelytoleadto

unexpectedeffectsduringthenextoperationsuchassuddenabortofthesamplerun.

CM7‐15400,

CM7‐15556,

CM7‐15734,

CM7‐15736

PerkinElmerLC200Autosampler:WhenupgradingfromearlierversionsofChromeleon

7CDStoChromeleon7.2CDSSR3,itisnecessarytoreloadthePerkinElmerLC200

Autosamplerdriverandconfiguretheloopsizewithintheconfiguration.Theuser

shouldthencheckallinstrumentmethodsusingthisautosamplertoensurethatthey

continuetofunctioncorrectly.

CM7‐15716PerkinElmerClarus400GC:SomeusersmustselectAutosystemXLinconfigurationin

ordertocommunicatewiththePerkinElmerClarus™400.

CM7‐20464Varian3800GC:ItisnotpossibletostartamanualdataacquisitioniftheGCisnot

ready(i.e.alltemperatures,pressuresandsoonareattheirsetpoints).Tryingtodoso

willgenerateaReadyCheckmessagedetailingwhatisnotready.

CM7‐12366Agilent5890DICECard:Pleasenotethefollowingwhenusingthe19257DICEcardwith

theAgilent5890GC:

ControlandacquisitionusingtheDICEcardisonlysupportedviatheserialinterface.

TheGPIBinterfaceisnotsupported.

DigitaldataacquisitionviatheserialinterfaceoftheDICEcardisonlysupportedfora

singlechannel;dualchanneldigitalacquisitionisnotsupported.

Currently,itispossibletoselectcertainillegalcombinationsintheConfigurationDialog

suchas:

Digitalacquisitionwiththe19254card.Thisisnotsupported.

Digitalacquisitionononedetectorandanalogacquisitionontheother.Acquisition

needstobeexclusivelydigitalorexclusivelyanalog.

WhenusingtheDICEcardtoacquiredatadigitally,the5890INETmodemustbesetto

“GLOBAL”not“LOCAL”.Failuretodosowillresultina“NoresponsefromGC”message

followingtheAcqOncommandintheaudittrail.

Notethatwhenperforminganalogacquisition,the5890INETmodeshouldstillbeset

to“LOCAL”(asdescribedintheonlinehelp).

CM7‐9675Agilent7890GC:ThereisabackwardcompatibilityissuethataffectstheAgilent7890

GCSamplerPositions.Whenusinga7890GCincombinationwitha7693sampler,

certainpositionsinthesamplercouldgiveamisspelledvaluetoamovecommand.This

hasnowbeencorrectedandcouldinrarecasesleadtoInstrumentMethodfiles

needingtobeupdatedtoavoiderrors.

CM7‐15293,

CM7‐18463

Agilent1100ObsoleteDriver:Occasionally,whenusingacombinationofolderand

newermodules,therawdatawasnotcorrectlyacquired.



Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage22





5.9 OtherLimitations

ID Description

SWFR‐2543SamplingDevicesThatDoNotUseuLAsUnitsforVolume:Althoughmostliquid

injectiondevicesexpectvolumestobeenteredinuL,thereareafewdevices(e.g.

ThermoAS‐HVandPerkin‐ElmerGCAutosampler)whichdonotuseµLastheirdefault

volumeunit.Ifoneofthesedevicesisconfiguredinthesameinstrumentthatalso

includesaninjectiondevicethatusesµL,problemsmaybeobservedwithvolume

validationinthesequencetableaswellasunitsassociatedwithvolumesinreports.

CM7‐21780NISTMSSearchandDemoLibraryNoLongerAutomaticallyInstalled:Incompatibilities

oftheNIST2008MSDemoLibraryinstallerwithWindow7and10couldcausethemain

Chromeleoninstallertohangorcrash.Toaddressthis,theNISTDemolibrary,andthe

associatedAMDISandMSSearchsoftwarearenolongerautomaticallyinstalledwhen

youinstallChromeleon.Ifdesired,thispackagemaybeinstalledmanuallyusingthe

setupprogramfoundinthe/Tools/folderoftheChromeleonDVD.Alternatively,one

mayinstallAMDISandMSSearchusingthefull(licensed)NISTlibraryinstaller.

NotethatMSlibrarysearchingwithintheChromatographyStudioisnotaffectedbythis

issue.

CM7‐21783PerformanceWhenImportingFixedCalibrationStandardsforMSSequences:When

workingwithsequencesofMSdata,importinginjectionsforuseinafixedcalibration

cantake1‐2minutestocomplete,dependingonthedata.

CM7‐18252ExportMSRawData:WhenacquiringMSdata,ChromeleonacquiresMSdataandall

othersignaldata,suchasUV,FLD,andpumppressuresignals,inseparateformats.Asa

result,whenMSdataisexported,non‐MSdataisnotexportedwiththeMSrawdata

file.

CM7‐20335ComparisonofOldReportVersionsShowsChangeinCmbxExportParameters:Ifa

reportwhichwascreatedinChromeleon7.2SR2orearlier,andmodifiedinSR3,hasits

historycomparedinSR4,thehistorywillappeartoshowthatthe"CmbxExport

Parameters"valuehaschangedfromTruetoFalse.Thisisduetoachangeinthe

defaultvalueofthisfield,anddoesnotrepresentanyuser‐modificationofthereport.

CM7‐17203ReportDesigner:Withsomedate/timeformattingsettingsinthereport,theorderof

monthanddaychangesforsomeformatsautomatically.ThesettingsintheReport

Templatecanchangebasedonthewindowsregionalsettings.Forexampleitisnot

possibletosetm.d.yyasformatwithGermanregionalsettings.TheReportTemplate

replacesthiswithd.m.yyyy.Thesubstitutionoccursforreportvariablesandnon‐report

variableentries.

CM7‐17841ReportDesigner:Ifusinganon‐ChineseformatastheregionalsettinginWindows,and

ChineseasthesettingforNon‐Unicodeprograms,thentheheaderonaChromeleon

reportisnotcorrectlydisplayedforvariables.IftheformatischangedtoChinese,then

everythingiscorrectlydisplayed.

CM7‐21331ReportVariablechm.massSpectrum("...").resolutionalwaysshows"0,5000":Themass

spectrumresolutionreportvariablereturnsaninternallyusedprocessingvalueinstead

oftheresolutionsettingdefinedintheMSinstrumentmethod.Itisrecommendedto

discontinueuseofthisreportvariableuntilfurthernotice.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage23

ID Description

CM7‐20449UserManagement:Login"Role"dropdownboxbecomesemptyafterupgradingto

Chromeleon7.2SR4.ThisisduetothefixforCM7‐18178"Roleswereofferedinthe

Logondialogue,eveniftheywerenotspecifiedasLogonroles".Toworkaroundthis

issue,enablethe"LogonRole"propertyintheuserdatabaseforalllogonrolesthat

usersneedtobeabletoselect.

CM6‐23886ExceptionErrorWhenRemovingUSB‐>COMPortAdapter:IfaUSB‐to‐RS232adapteris

usedtoprovideCOMcommunicationbetweenanInstrumentPCor247Instrument

Controllerandaninstrument,andtheUSBconnectionisunplugged,Chromeleon

reportsaFatalErrorintheInstrumentAudittrail.TheUSB‐to‐RS232adaptershouldnot

bedisconnectedfromtheInstrumentPCor247InstrumentControllerwhileitis

powered‐on.

CM7‐19336Chromeleon6Import:DuetochangesinAuditingbetweenChromeleon6and

Chromeleon7,whenaChromeleon6SequenceisimportedintoChromeleon7,someof

thetextdisplayedintheInstrumentAudittrailwillnotappearexactlyasitdidin

Chromeleon6.Refertothetopic"ViewingChromeleon6Data"intheonlinehelpfor

furtherinformation.

CM7‐21399InjectionVariables'AutoDilutionRatio'and'RetentionTimeStandard':AutoDilution

RatioandRetentionTimeStandardcolumnsarenotavailableinthecustomfilter

conditionsforinjectionrecords(e.g.,intheIRCeditororsummaryreport).

CM7‐22111MixedInstallationswithChromeleon7.2SR5DomainController:Ifyouhaveanexisting

installationofChromeleon<7.2SR1,thefollowinglimitationsapplyduringanupgrade:

StationsthathaveChromeleon7.2orbelowinstalledwillnotseeanydatavaultsor

instrumentsthathavebeencreatedwithChromeleon7.2SR5,untilafterthosestations

areupgradedto7.2SR5.

ItisnotpossibleforaChromeleon7.2(andbelow)stationtojoinaChromeleon7.2SR5

domain.

StationsthathaveChromeleon7.2orbelowwillnotreceiveanyupdatesfromthe

DiscoveryServiceaftertheChromeleondomaincontrollerhasbeenupgradedto7.2

SR5,andwillonlyseeresourcesthatwerealreadyinexistenceandcached.

PleaserefertotheEnterpriseDocumentationforguidanceonupgradinganolder

installationofChromeleon7toChromeleon7.2SR5.

CM7‐22145Discrepancyin“LastModified”Time:Owingtodifferingroundingmethodsused,itis

possiblethatthevalueofthe"lastmodified"timeforanobjectinasequencehasa

differenceof1secondbetweentheclientdisplayandthevalueshowninareport.For

moredetails,pleaseseetheon‐linehelp.

CM7‐24058Console:TheneweWorkflowoption"PreserveLayout",introducedinChromeleon7.2.6

isnotbackwardscompatiblewitholderversionsofChromeleon.Ifaclientwithan

earlierversionattemptstoopenaneWorkflowforwhichthisoptionisenabled,the

errormessage"Cannotload,asthedatawascreatedwithanewerChromeleon

version.”Isdisplayed.

CM7‐20637LogonwithCurrentWindowsAccountafterDisconnectingNetworkFailswith

MisleadingErrorMessage:Intheeventofalossofnetworkconnectiononasystem

usingLDAPlogon,attemptingtologontoChromeleonagainwiththesameaccount

detailsresultsinamisleadingerrormessage"Theusernameorpasswordare

incorrect."

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage24

ID Description

CM7‐23033LegacyUpload:Withreplicationframeworkdisabled,whentryingtomodifyasequence

whiletheautomaticuploadisalreadyinprogresstheuploadmayfailinveryrarecases

anditisnotpossibletoremovethesequencefromtheinstrumentqueuebyretryof

theupload.Torecoverthesequenceacopyofthesequencehastobestoredmanually.

Chromeleon7.2SR5addsanaudittrailentrytothemanuallyuploadedsequencethat

referstotheoriginalsequencesothattraceabilityisensured.

ThermoFisherScientificrecommendstoenablethereplicationframeworkwith

Chromeleon7.2SR5toavoidtheproblem.

CM7‐23481FatalErrorinChromeleon7RealTimeKernelService:WhenleavingtheInstrument

ConfigurationManageropenoverextendedperiodsoftimetheChromeleonRealTime

KernelServicemightstopunexpectedlywithafatalerrorintheWindowsEventLog.







5.10 ObsoleteDrivers

Chromeleonincludesanumberofobsoletedriversinordertoprovidebackwardcompatibilityof

existinginstallations:

 Agilent/HP1200HPLCSystem

 AI1310/3000GCSampler‐10ul

 AI1310/3000GCSampler‐5ul

 AI1310/3000GCSampler‐5ul‐155Vials

 AI1310/3000GCSampler‐5ul‐105Vials

 AI1310/3000GCSampler‐10ul‐155Vials

 AI1310/3000GCSampler‐10ul‐105Vials

 PALSamplerforGC

 PALSamplerforLC

 TRACE1300SeriesGC(FirstgenerationdriverthathasbeensupersededbyTRACE1300SeriesGC

IIdriver)

Pleasenotethatissuesreportedforanyofthesedriverswillnolongerbeaddressed.Ifyouareusing

oneofthesedriversThermoFisherScientificrecommendsmigratingtoasupporteddriverassoonas

possible.

5.11 DefectsUnderInvestigation

Thefollowingdefectshaveonlyoccurredveryrarely,anddatanecessaryforinvestigation,suchas

logfilesandbackups,areinsufficienttoreproducetheproblem.Despitesignificanttestingeffortsin

variousconfigurationswecouldnotreproducethisbehaviorinsystemsthataresetupand

configuredasrecommendedbyThermoFisher.ThermoFisheristhereforeunabletoidentifytheroot

causeoftheproblemandprovidetechnicalmodificationsofthesoftwarethatwouldallowusto

confidentlystatethatwepreventfutureincidentsofsuchbehavior.Wearecontinuinginvestigation

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage25

oftheseissuesbutwouldliketosharesymptomsofthisbehaviorwithourcustomerbaseandgive

recommendationstoremediatefromthebehaviorifitoccurs.

Note:Ifyouareaffectedbyanyofthesedefects,pleasecollectaSystemStatusReport

immediatelyandcontactyourlocalThermoFisherrepresentativeforfurtherassistance.

5.11.1 EmptyInjectTimeandGUIDFieldsintheInjectionRecord[CM7‐22738]

EmptyInjectTimeandGUIDfieldshavebeenseeninafewsingleinjections.Rawdatahavebeen

successfullyacquiredandstoredonthelocalInstrumentPC.TheInjectionAuditTrailonthe

InstrumentPCcontainscompleteinformation,includingthemissingdetails.Toofewinstanceshave

beenreportedtoidentifytherootcauseofthisproblem.

Note:Ifyouareaffectedbythisproblem,pleasecontactyourlocalThermoFisherrepresentative

forassistancewithrecoveryofthemissinginjectiondetails.

5.11.2 InstrumentAuditTrailsArenotProperlySaved/WrittenonthelocalData

Vault[CM7‐23051]

Inoneinstallation,afewSequencesabortedwiththefollowingerrormessagesintheaudittrail:

“Theaudittrailwasunavailableforsometime.Severalaudittrailmessagesarelost.Theyhavebeen

loggedtothefile"Dionex\Chromeleon\Log\AuditTrailMessages.log"inthe(common)application

datafolder.”

DuringinvestigationofthelogfilesofaffectedInstrumentControllerPCserrorsofslowfile

operationsonthelocalharddrivehavebeenfound:

“SQLServerhasencountered1occurrence(s)ofI/Orequeststakinglongerthan15secondsto

completeonfile[C:\ProgramData\Dionex\Chromeleon\DataVaults\XVault\XVault_log.LDF]in

database[XVault](6)“

Ithasbeenconfirmedthatthefailurewascausedbypoordiskdriveperformanceandonlyoccurred

overalimitedperiodoftime.Chromeleon7.2SR5introducesadditionalerrorhandlingandreporting

sothatsimilarerrorscanbeidentifiedmoreeasily.

5.12 FunctionalDifferencesbetweenChromeleon7.2andChromeleon

6.8

Chromeleon7.2SR5MUaimplementsthevastmajorityofChromeleon6.8features,andingeneral,

hasaricherfeaturesetthanChromeleon6.8.However,afewChromeleon6.8featuresremaintobe

implementedontheChromeleon7platformandafewwillneverbeimplemented,sincetheyare

nowobsoleteornolongerrelevant.Ifaparticularmissingfeatureisimportanttoyou,please

contactyourlocalThermoFisherScientificrepresentativetofindoutifthatfeatureisintheproduct

developmentplans.



Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage26

6 Backward/ForwardCompatibilityIssues

6.1 ThermoScientificVanquishChargedAerosolDetector[CM6‐23499]

AnyInstrumentMethodscreatedfortheVanquishChargedAerosoldetectorwithChromeleon7.2

SR2MUaandearliermayneedtobeupdatedduetochangesinthedriverintroducedinChromeleon

7.2SR2MUb.

6.2 ThermoScientificVanquishAutosampler[CM6‐23405]

AnyInstrumentMethodscreatedfortheVanquishAutosamplercontainingtheWashSpeedproperty

willneedtobeupdated.TheWashSpeedvalueneedstobedividedby0.06inorderforthe

InstrumentMethodtoworkcorrectly.

6.3 ThermoScientificTriPlusRSH

Thecurrentdriverforthisinstrumentisincompatiblewithfirmwareolderthanversion2.4.

6.4 ThermoScientificTriPlus300HS

Thecurrentdriverforthisinstrumentisincompatiblewithfirmwareolderthan2001.9.0.

6.5 ThermoScientificTriPlusLS‐100

Thecurrentdriverforthisinstrumentisincompatiblewithfirmwareolderthanversion2.4.

6.6 ThermoScientificTSQQuantiva

Thedriverversion1.1QF1forthisinstrument,includedinthisServiceRelease,maynotbe

compatiblewithexistingTSQQuantivamassspectrometersrunningdriverversion1.0withouta

hardwareupdate.PleasecontactyourlocalMSserviceengineerbeforeattemptingtoupgradethe

unit.

Note: NewTSQQuantivamodulesfromthefactoryarenotaffectedbythisissue.

6.7 ThermoScientificTSQQuantivaandEndura

Thedriverversion1.1SP1fortheseinstrumentsmaynotbecompatiblewithexistingTSQQuantiva

andEnduramassspectrometersrunningdriverversion1.0withoutahardwareupdate.Please

contactyourlocalMSfieldserviceengineerbeforeattemptingtoupgradetheunit.

Note:NewTSQQuantivaandEnduramodulesfromthefactoryarenotaffectedbythisissue.

6.8 TSQQuantivaandEnduraInstrumentMethod[CM7‐18759]

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage27

InstrumentmethodscreatedwitholderversionsoftheTSQQuantivaandEndurainstrumentmethod

editorcannotbeopenedwithnewerversionsofthemethodeditor.Ifalargenumberofinstrument

methodshavealreadybeencreatedforregularuse,upgradeoftheTSQQuantivaandEnduradriver

isnotrecommended.ContactyourlocalThermoFisherScientificrepresentativeforadditional

details.

6.9 SignedSequences[CM7‐16374]

SequencesthathavebeensignedwithinChromeleon7.2SR1willfailverificationaftercopyingwithin

laterversionsofChromeleon7.2CDS.

Chromeleon7

TPL_Release‐Notes‐Chromeleon‐7_0571templatedated29‐Sep‐2016,version1.1



ReleaseNotesPage28

7 Appendix

ThischaptercontainsgeneralInformationaboutServiceReleases,ReleaseNotes,OnlineHelp,and

ContributedContent.

7.1 ReleaseNotes

TheReleaseNoteslistthenewfeaturesandimprovementsofthecurrentrelease.Includedinthese

ReleaseNotesareallofthefunctionalityandbugfixesfromChromeleon7.2SR5MUaand

Chromeleon7.2SR5MUb.FordetailsaboutChromeleon7.2SR5andotherpreviousreleases,refer

totherelevantreleasenoteswhichcanbefoundontheChromeleon7.2.6DVD.

7.2 OnlineHelp

Ingeneral,newfeatures,updatesanddriversthatareintroducedwiththisreleasearedescribedin

anupdatedOnlineHelpthatisdistributedwiththerelease.

7.3 ContributedContent

TheChromeleon7diskcontainsafoldertitledContributedContent.Thisfoldercontains:

 DemonstrationMaterial

 LocalizedDocuments

 LocalizedePanels

 LocalizedReportTemplates

 eWorkflowTemplates

 UserManagementExample

 CharlieMousePointer

Note:ThefilesintheContributedContentfolderhavenotbeentestedandvalidatedaccordingto

ThermoFisherScientificSoftwareDevelopmentCycleguidelinesmodeledafterISO9001:2008

standards.ThermoFisherScientificassumesnoresponsibilityforanyerrorsthatmayappearin

thecontentprovidedintheContributedContentfolder.





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USA

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