Philips 89000 User Manual Rotational IVUS Image Interpretation Pocket Guide Revolution
User Manual: Philips 89000 Rotational IVUS image interpretation pocket guide Philips Volcano - Revolution 45 MHz rotational IVUS imaging catheter89000
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Catheter Rotational IVUS Image Interpretation Pocket Guide CONTENTS 4 Normal Vessel 6 Concentric Mixed Plaque 8 Eccentric Mixed Plaque 10 Fibrous Plaque 12 Plaque with Calcium 14 Under Expanded Stent 16 Stent with Complete Apposition 18 Stent with Malapposition 20 Vessel Branches Merging 22 Vein Graft Dissection 24 Intra Luminal Thrombus 26 Hi-Q™ Imaging Options 2 3 NORMAL VESSEL In a normal vessel, the lumen border is almost indistinguishable from the vessel border. While IVUS allows visualization of vessel and lumen, angiograms only provide a shadow of the lumen. In patients with diffuse disease, relying on the angiogram alone can potentially lead to underestimation of stenosis. The lumen border is drawn inside the intima or plaque. The intimal layer is normally not seen unless it has begun to thicken. The catheter mask (red area) indicates the location of the ultrasound transducer. The media is the dark band between the adventitia and the intima. Lumen Border Catheter Mask Vessel Border 4 5 CONCENTRIC MIXED PLAQUE Concentric plaques are distributed circumferentially in the vessel. Concentric plaques tend to occur in areas of negative remodeling; use of angiography alone could result in too large a stent diameter. Mixed plaque is a combination of tissues of varying echogenecity. The distribution of light and dark may be distinct, or light and dark variations may be intermingled as shown here. 6 1. Jasti, et al. Correlations between fractional flow reserve and intravascular ultrasound in patients with an ambiguous left main coronary artery stenosis Circulation, 2004;110:2831-2836. 2. Jose M. de la Torre Hernandez et al. Prospective Application of Pre-Defined Intravascular Ultrasound Criteria for Assessment of Minimum Lumen Area (MLA) can define a threshold for a significant stenosis to determine the need for catheter-based or surgical intervention. • MLA < 4 mm2 in LAD, LCX, and RCA vessels > 3 mm in diameter correlates with physiological significance1 • MLA < 6 mm2 in left main correlates with FFR < 0.75 indicating physiological significance1,2,3 Intermediate Left Main Coronary Artery Lesions: Results From the Multicenter LITRO Study, J Am Coll Cardiol, 2011 58: 351-358. 3. Levine et al. 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. J Am Coll Cardiol, 2011; 58:44-122. 7 ECCENTRIC MIXED PLAQUE Eccentric plaques are distributed noncircumferentially in the vessel; this makes the assessment of disease by angiography especially prone to underestimation or overestimation depending on the angle of view. Calcium is indicated by very bright areas with acoustic shadowing that blocks out the image behind. This shadowing occurs because the high density of calcium dampens the ultrasound echo. Nearby vessels on the periphery can be seen moving in and out of the field of view and can be used as landmarks. Side Branch Side Branch 8 Acoustic Shadowing 9 FIBROUS PLAQUE These plaques have an intermediate echogenicity between soft (echolucent) atheromas and highly echogenic calcific plaques. Fibrous plaques exhibit little or no acoustic shadowing. 10 11 PLAQUE WITH CALCIUM There are two large bands of calcium in this plaque with acoustic shadowing arcs behind them. Calcium is indicated by very bright areas with acoustic shadowing that blocks out the image behind it. Reverberations may also been seen. This shadowing occurs because the high density of calcium prevents the ultrasound from passing through. Detection of calcium is a critical factor in determining the optimal PCI strategy. Study data comparing IVUS and angiographic based assessments of calcium reported that IVUS detected calcium significantly more often.* Calcium Reverberation Shadowing Reverberation Calcium 12 *Mintz et al. Patterns of calcification in coronary artery disease. Circulation 1995; 91:1959-1965. 13 UNDER EXPANDED STENT Stent struts appear as bright marks spaced around the lumen (eleven struts seen here). Large presence of plaque behind stent struts may indicate under-expansion. Device size is an independent predictor of stent thrombosis* Area of Under Expansion 14 * Witzenbichler et al. Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents: The ADAPT-DES Study. Circulation. Published online November 26, 2013. 15 STENT WITH COMPLETE APPOSITION Complete apposition is indicated by consistent stent strut contact with tissue. Complete apposition does not guarantee that a stent is not under-sized or under-expanded. Area of Complete Apposition 16 17 STENT WITH MALAPPOSITION Malapposition is indicated by blood visible behind stent struts. Stents may be completely or only partially malapposed depending on how much of the stent is in contact with the lumen wall. Blood may appear as a very faint speckle or black on grayscale IVUS. Area of Malapposition 18 19 VESSEL BRANCHES MERGING Nearby side branches can act as landmarks. Side branches can be used to determine where or where not to stent within a vessel. Side Branches Merging 20 21 VEIN GRAFT DISSECTION A dissection, or tear in the vessel wall can be seen as a flap with blood flow behind it. Only the intimal layer is dissected. When detecting a dissection, the catheter may be flushed with contrast to reduce the blood speckle. Dissection Area 22 23 INTRA LUMINAL THROMBUS Thrombus is usually circular in appearance and non-stationary. When detecting a thrombus, the catheter may be flushed with contrast to highlight the contours. When viewed during a pullback, thrombus first appears small in size becoming larger and then smaller again. Thrombus 24 25 HI-Q™ IMAGING OPTIONS Hi-Q OFF Hi-Q™ Imaging1 Allows You to Customize Your Image to Better Identify Lumen Features Imaging equivalent to systems with software versions prior to v.3.3. Choose from three high quality 2, optimized imaging modes with different levels of darkness and fineness of blood speckle: May help differentiate between tissue and blood along the lumen border May help identify stent struts, dissection, or other lumen features Hi-Q LEVEL 1 Imaging with a darker and finer blood speckle appearance than in the Off mode. Level is also the default mode1 for new systems. Hi-Q LEVEL 2 Imaging with an even darker and finer blood speckle appearance than in the Level 1 mode. 26 1. Available on all Revolution® catheters when using v3.3 software or higher. 2. Catheter must be plugged in with Image On; Selection accessible via the Adjust Image Menu. 27 See What You’ve Been Missing With IVUS Stent Sizing Angiography Must rely on “eyeball” estimate. Calcium IVUS Enables you to make lumen and reference vessel measurements that can be used when selecting stent size. Stent Expansion and Apposition Dissection Angiography Cannot see the vessel wall to verify optimal placement. Angiography Cannot determine where the dissection begins. IVUS User-defined cross-sectional area measurements and views allow verification and documentation of stent placement. Normal Vessels vs. Diffuse Disease Angiography Tends to underestimate degree of stenosis in diffuse disease1 or with positive remodeling. IVUS Helps you distinguish normal from abnormal vessels and find the location of disease in patients with a normal angiogram. Concentric and Eccentric Plaques Angiography Must rely on “eyeball” estimate. Assessment of eccentric plaque lesion size especially prone to error based on angle of view. 28 Angiography Less sensitive than IVUS for detecting calcium1 IVUS Makes the presence of calcium clear, helping to identify lesions that need pre-treatment. IVUS Can be determined. Thrombus Angiography Difficult to determine. IVUS Can be determined. Side Branches Merging Angiography Cannot tell how diseased the vessels are. IVUS Helps to determine where to place or not place a stent as well as providing information on the disease state in the ostium and side branch. IVUS Helps you get an accurate lumen area to determine lesion significance and stent size. 1. Reference vessels are diseased 93% of the time. Mintz et al. Patterns of Calcification in Coronary Artery Disease A Statistical Analysis of Intravascular Ultrasound and Coronary Angiography in 1155 Lesions JACC 25; 7:1479-85, June 1995. 29 Volcano Corporation Corporate Headquarters 3721 Valley Centre Drive, Suite 500 San Diego, CA 92130 USA Phone: 800-228-4728 Fax: 858-720-0325 Volcano Corporation Manufacturing Headquarters 2870 Kilgore Road Rancho Cordova, CA 95670 USA Phone: 800-228-4728 Fax: 916-638-8812 Volcano Europe SPRL/BVBA Europe Headquarters Excelsiorlaan 41 B-1930 Zaventem Belgium Phone: +32-2-679-1076 Fax: +32-2-679-1079 Volcano Japan Co., Ltd Japan Headquarters Hamamatsucho Square 6F 1-30-5, Hamamatsucho, Minato-ku, Tokyo 105-0013, Japan Phone: +81-3-6430-9400 Fax: +81-3-6430-9401 Volcano, the Volcano logo, and Revolution are registered trademarks of Volcano Corporation. Hi-Q is a trademark of Volcano Corporation. 600-0000.01/002
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